Scapuloperoneal syndrome is a rare disease entity characterized by weakness and atrophy of proximal shoulder girdle and distal anterolateral leg muscles. The disease is inherited by a variable mode. Electromyography and muscle biopsy show denervation and dystrophic changes.

We report one case of scapuloperoneal syndrome with clinical, electrophysiological, and muscle biopsy findings. Twenty two year-old male patient was admitted because of progressive gait disturbance. Weakness and atrophy of scapuloperoneal area muscles were noted without sensory loss. The Gower's sign was positive and pes cavus deformity was developed due to achilles tightness on both sides. The deep tendon reflexes were hypoactive and pathologic reflexes was absent. The muscle enzyme study and nerve conduction study was normal. The electromyographic study revealed combined peripheral motor neuropathy (axonal type) and myopathy. The muscle biopsy study revealed myopathic predominant findings. This case was considered as mixed pattern scapuloperoneal syndrome of sporadic form.