The usefulness of performing late response studies for the detection of uremic polyneuropathy has been demonstrated. It has been shown that significant prolongation of the minimal latencies of the H-reflexes and the F-responses and significant correlation with conventional method of motor and sensory conduction. The 30 cases of uremic polyneuropathies are studies, as possible as, with conventional and late response study comparing to 25 cases of normal controls.

The conclusions are as followings.

1) Statistically significant(p<0.001) prolongation of motor and sensory conduction velocities of tibial nerve in uremic polyneuropathies.

2) The late response study performing on uremic polyneuropathies revealed statistically significant (p<0.005 in F-reponses and p<0.001 in H-reflex) prolongation of latency and slowing of their conduction velocities compared to normal controls.

3) The H-reflex latency and conduction velocity of its pathway would be taken significant role in the effect of treatment(Hemodialysis) and prognosis of uremic polyneuropathies.

4) The significant prolongation of minimal latencies of H-reflex is present at a time of when conventional methods of motor and sensory conduction do not show an abnormality in individual patients.