| The Effect of Paratendinous Aprotinin Injection in Patients with Rotator Cuff Tendinitis. |
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Jung, Hyun , Seo, Jeong Hwan , Ko, Myeng Hwan , Sim, Young Joo |
1Department of Rehabilitation Medicine and Institute for Medical Sciences, Chonbuk National University Medical School, Korea. vivaseo@chonbuk.ac.kr
2Department of Rehabilitation Medicine, Kosin University College of Medicine, Korea. |
| 어깨 회전근 건염 환자에서 아프로티닌 주사 후 통증 및 기능의 호전 |
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정현, 서정환, 고명환, 심영주1 |
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전북대학교 의과대학 재활의학교실 및 임상의학연구소, 1고신대학교 의과대학 재활의학교실 |
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| Abstract |
Objective
To determine the therapeutic effect of paratendinous injection of aprotinin, a polyvalent inhibitor of inflammatory proteolytic enzyme, in patients with shoulder tendinitis.
Method
Thirty patients with shoulder tendinitis diagnosed with ultrasonography were included. Patients were assigned to one of two groups at random to receive paratendinous injection. One group received a paratendinous aprotinin 1.5 ml and 1% lidocaine 2 ml injection of shoulder 2∼5 times at 1 week apart. The other group received a paratendinous injection one time with mixture of triamcinolone 40 mg and 1% lidocaine 2.5 ml. The effect of treatment was assessed with the visual analogue scale (VAS), and the patients' life activities were assessed with the Western Ontario rotator cuff (WORC) index.
Results
The VAS of the two groups showed improvement at 1 week (aprotinin group: 2.9±0.7, triamcinolone group: 3.7±1.2) and 4 weeks (aprotinin group: 2.1±1.0, triamcinolone group: 2.4±1.0) after injection compared with pre- injection status (aprotinin group: 8.6±1.3, triamcinolone group: 8.2±1.3)(p＜0.01) and the WORC index of the two groups showed improvement at 1 week (aprotinin group: 36.5±7.8, triamcinolone group: 53.2±12.3) and 4 weeks (aprotinin group: 33.4±6.2, triamcinolone group: 31.4±8.8) after injection compared with pre-injection status (aprotinin group: 116.2±29.1, triamcinolone group: 123.5±37.0)(p＜ 0.01). There was no significant difference in the improvement of the VAS scores and WORC index between the two groups.
Conclusion
The short term effect of paratendinous aprotinin injection in patients with shoulder tendinitis was as good as triamcinolone injection, although more frequent injection was necessary. (J Korean Acad Rehab Med 2008; 32: 56-61) |
| Key Words:
Shoulder tendinitis, Aprotinin, Steroid |
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