The purpose of present study is to compare the results about urinary tract infection between the antibiotic (ofloxacin) administration and bladder irrigation using KM_nO₄ solution in patients with neurogenic bladder.

The most common kind of infectious bacteria was Pseudomonas aeruginosa but Klebsiella pneumonia and Escherichia coli were also common. When ofloxacin was administered, the rate of successive treatment was 70.0%. But when bladder irrigations with KM_nO₄ solution were tried, the rate of successive treatment was only 16.7%. The results were stastically significant.

The treatment results concerned with bladder tone(positive and negative ice water test), voiding method(self-voiding or intermittent catheterization and indwelling catheterization or condom drainage) and disability type(cerebrovascular accident and spinal cord injury) were not statistically significant.

When we treat the urinary tract infection associated with neurogenic bladder, ofloxacin administration is better than bladder irrigation using KM_nO₄ solution.