Urinary tract infection(UTI) is one of the most common complications in the patients who have neurogenic bladder, and if proper management were not given, there could be serious complication, such as vesicoureteral reflux, hydronephrosis, urinary stone, and renal failure. An early and appropriate antibiotic treatment is crucial to avoid these cmplications, and the guidelines of antibiotic choice depend on the type of causative microorganisms and results of sensitivity test to various antibiotics. But the incidence of causative microorganism of UTI and their antibiotic sensitivity may change over time. So I retrospectively analysed the change of causative microorganism and antibiotic sensitivity pattern during 5 years(1990-1994 year). The results are as followed:

1) The incidence of Gram(-) rods was gradually decreased, and Gram(+) cocci increased.

2) Pseudomonas aeruginosa and Escherichia coli were still one of the most common causative microorganisms but their incidence was decreased, and the incidence of Enterococcus, Staphylococcus increased.

3) Antibiotic sensitivity of causative microorganism had not changed statistically over 5 years.