Fifteen spinal cord injured patient with neurogenic bladder dysfunction were treated with intermittent catheterization and pharmacotherapy. Clinical approach of pharmacotherapy for neurovesical disorders is aimed to promote bladder emptying and storage.

Six patients showed neurogenic bladder dysfunction of detrusor sphincter dyssynergia. There of them were treated with pharmacological inhibition of the smooth sphincter and one patient was treated with pharmacological inhibition of both sphincters. Mean duration of bladder retraining of the 6 patients was 13.8 days with 100 percent succesful bladder retraining with 150cc of acceptable maximal residual urine volume.

Rest of patients showed incontinence. Eight of 9 patients were treated with pharmacological combination of inhibition of bladder contractility and increase of outlet resistence. One patient was treated with only pharmacological increase of outlet resistence. Mean duration of bladder retraining for incontinence was 11.5 days with good results.