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Journal of the Korean Academy of Rehabilitation Medicine 1999;23(5):893-898.
Effects of Electrical Stimulation on Nerve Regeneration in Peripheral Nerve Injured Rats.
Kim, Yeung Ki , Ahn, Sang Ho , Jang, Seung Ho , Park, Hea Woon , Sin, Hyun Jin
1Department of Rehabilitation Medicine, Yeungnam University College of Medicine.
2Department of Medical Engineering, Yeungnam University College of Medicine.
흰쥐의 말초신경 손상 후 전기자극이 신경 재생에 미치는 효과
김영기, 안상호, 장성호, 박해운, 신현진1
영남대학교 의과대학 재활의학과 및 1의공학과
Abstract

Objective
To evaluate the efficacy of direct current electrical fields and peripheral external electrical stimulation to promote regeneration of the transected rat sciatic nerve.


Method
Four groups were studied: three experimental groups and one control group. Cathod distal (CD) group; nerves were treated with 1.0 μA direct current with the cathode oriented distally to the lesion, anode distal (AD) group; nerves were treated with the anode oriented distally to the lesion, external stimulation (ES) group; nerves were treated with 3 mA, 60 Hz, galvanic current, using a ring electrode at ankle joint 3 times per day. No current was delivered in control group. Electrophysiologic and functional assessments were conducted at 3 weeks postoperatively.


Results
All experimental groups showed significantly higher electrophysiologic and functional improvement than the control group. However, there is no significant differece in improvement among experimental groups.


Conclusion
Both direct current electrical field and peripheral external electrical stimulation can effectively promote peripheral nerve regeneration.

Key Words: Electrical stimulation, Nerve regeneration, Nerve injury


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