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Journal of the Korean Academy of Rehabilitation Medicine 1999;23(6):1110-1117.
A Functional MRI Study of Brain Language Network in Korean Adult.
Kim, Yun Hee , Kim, Seong Yong , Kim, Hyoung Ihl , Hong, In Ki , Parrish, Todd B , Chung, Chang Oh , Shin, Hyun Ho , Kim, Hyun Gi
1Department of Rehabilitation Medicine, Chonbuk University Medical School, Chonju.
2Epilepsy Surgery Program Honam Medical Center.
3Department of Information and Communications, Kwangju Institute of Science and Technology, Kwangju.
4Department of Radiology, Northwestern University Medical School, Chicago, USA.
5Faculty of European Language and Literature, College of Humanities, Chonbuk National University, Chonju.
기능적 뇌 자기공명영상을 이용한 한국 성인의 뇌 언어신경망 연구
김연희1, 김성용1, 김형일2, 홍인기3, Todd B. Parrish4, 정창오2, 신현호2, 김현기5
1전북대학교 의과대학 재활의학교실, 2호남병원 간질수술팀, 3광주과학기술원 정보 및 통신공학과, 4Department of Radiology, Northwestern University Medical School, 5전북대학교 인문과학대학 유럽어문학부
Abstract

Objectives: To report the results of functional magnetic resonance imaging (fMRI) experiment to delineate brain network for auditory language tasks in normal Korean adults.


Method
Five normal right-handed Korean males, aged 20∼33 years, were investigated using fMRI technique. Language tasks consisted of auditory listening and verb generation tasks. In fMRI, twenty slices were obtained for each functional volume using single shot echoplanar image sequences. Eighty-four volumes were obtained for each functional run. Data were motion corrected, coregistered, normalized, and statistically analyzed using SPM-96 software (Wellcom Department of Cognitive Neurology, Oxford, UK).


Results
Functional activation were detected in superior temporal region (coordinates: x=⁣64, y=⁣42, z=2) in the left side and superior to middle temporal lobe (coordinates: x=50, y=⁣20, z=2) in the right side for auditory listening task. Auditory verb generation task activated inferior frontal gyrus (coordinates: x=⁣56, y=16, z=14), superior temporal region, and medial frontal region in the left side. Right temporal lobe was also activated in the superior to middle temporal areas. Activation was more extensive in the left side for both language tasks.


Conclusion
Our results can remarkably delineate cortical and subcortical regions subserved for auditory language processing. These results can be contributing to understand the underlying mechanism of language disorders in brain-injured patients and to investigate the pattern of reorganization of language network after rehabilitation.

Key Words: Functional MRI, Brain network, Auditory language


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