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Journal of the Korean Academy of Rehabilitation Medicine 2001;25(5):795-802.
Nerve Conduction Study on Patients with Severe Liver Disease and Its Change after Transplantation.
Lee, Jung Hwan , Jung, Woo Jung , Cho, Sung Chan , Choi, Kyoung Hyo , Lee, Seung Kyu , Ha, Sang Bae
1Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine.
2Department of General Surgery, Asan Medical Center, University of Ulsan College of Medicine.
중증 간질환 환자의 신경전도검사 소견과 간이식술 후의 변화
이정환, 정우정, 조성찬, 최경효, 이승규1, 하상배
울산대학교 의과대학 서울중앙병원 재활의학과 및 1일반외과
Abstract

Objective
To investigate the character of peripheral neuropathy associated with end-stage liver disease and the effect of liver transplantation on peripheral neuropathy.


Method
Twenty five patients admitted for a liver transplantation were involved in this study. All patients underwent nerve conduction study before liver transplantation and 6 months after liver transplantation. Based on results of this study, motor amplitude (MAS), motor velocity (MVS), sensory amplitude (SAS), and sensory velocity score (SVS) were calculated. Neuropathy symptom score (NSS), and neuropathy disability score (NDS) were estimated. The scores from the nerve conduction study were compared with NSS and NDS to find out the correlation between them. The changes in nerve conduction study, NSS and NDS after liver transplantation were evaluated.


Results
All patients had abnormalities on their nerve conduction study preoperatively, but 10 patients (40%) showed normal findings 6 months after transplantation. Only SAS disclosed significant correlation with NDS preoperatively. SAS, SVS, and MVS showed significant correlation with NDS after transplantation. SAS and MVS substantially increased after transplantation.


Conclusion
Nerve conduction study showed the improvement both in sensory and motor nerve after liver transplantation. The correlation between the nerve conduction study and clinical estimates after liver transplantation was closer than before the transplantation.

Key Words: Liver transplantation, Nerve conduction study


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