J Korean Acad Rehabil Med Search

CLOSE


Journal of the Korean Academy of Rehabilitation Medicine 2004;28(4):352-357.
Protective Effect of Exercise on Peripheral Nerve Injury Induced by Ischemia/Reperfusion in Rats.
Yoon, Joon Shik , Kim, Sei Ju , Choi, Jong Woo , Moon, Jun
Department of Rehabilitation Medicine, Korea University College of Medicine, Korea. rehab46@medimail.co.kr
백서 말초신경의 허혈-재관류 손상 후 운동치료의 예방적 효과
윤준식, 김세주, 최종우, 문준
고려대학교 의과대학 재활의학교실
Abstract
Objective
To investigate the effect of swimming exercise on the recovery after ischemia/reperfusion injury.
Method
Forty male Sprague-Dawley rats were tested. Two groups of 20 rats were formed: 1- and 3-hours ischemia groups. Finally the groups were further divided into 2 groups that went through swimming (swimming groups) and those not (control groups). Baseline recordings of electromyographic and sciatic function index (SFI) were performed, then the femoral vessels of the rat were ligated for the complete ischemia. The reperfusion process was done according to the preset time. The methods to evaluate the functional status of nerve were the nerve conduction study (NCS), SFI and histologic study.
Results
On the fourth week of experiment, amplitude of compound muscle action potentials was large in swimming groups compared to the control groups (p<0.05). On the third week, amplitude was large in 1 hour swimming group compared to the control group. The muscle fiber was large in diameter in 1-hour-ischemic group at 4 week compared to the control, and the sciatic function index showed same results at the 3 hours group.
Conclusion
The groups which swimming exercise done early after ischemia/reperfusion got better results compared with the nonswimming group (p<0.05). The exercise had beneficial effect on motor function recovery after ischemia/ reperfusion injury. (J Korean Acad Rehab Med 2004; 28: 352-357)
Key Words: Ischemia-reperfusion injury, Complete ischemia, Swimming exercise, Recovery


ABOUT
ARTICLE TYPES

Browse all articles >

BROWSE ARTICLES
AUTHOR INFORMATION
Terms of Use   |   Privacy Polity
Editorial Office
Department of Rehabilitation Medicine, Seoul National University Hospital
101 Daehak-ro, Jongno-gu, Seoul, Korea
Tel: +82-10-8678-2671    Fax: +82-2-6072-5244    E-mail: edit@e-arm.org; edit.karm@gmail.com
Business Registration: 110-82-07460                

Copyright © 2024 by Korean Academy of Rehabilitation Medicine.

Developed in M2PI

Close layer