Objective
To evaluate the effect of hyperbaric air therapy (HAT) on activity of cerebral motor cortex Method: Eighteen right-handed subjects were recruited, who had no brain lesion and did not take any medication that can affect brain function. Experimental group (n=9) underwent motor evoked potential (MEP) study by transcranial magnetic stimulation before and after 1-hour HAT. Control group (n=9) also received motor evoked potential study twice with 1 hour interval. The cortical activity was evaluated with parameters such as resting motor threshold (rMT), amplitude of MEP, intracortical inhibition (ICI) and intracortical facilitation (ICF) and recruitment curve (RC). Results: There was no significant difference of rMT, MEP, ICI, ICF and RC between experimental group and control group. Conclusion: One -hour hyperbaric air therapy could not modulate any cortical motor activity in health human brain. (J Korean Acad Rehab Med 2005; 29: 38-42)