The Change of Blood Glucose and Cortisol Levels after Three Consecutive Epidural Steroid Injections. |
Kim, Dong Gun , An, Hyun Mee , Jung, Kyu Young |
Department of Physical Medicine and Rehabilitation, Busan Paik Hospital, Inje University College of Medicine, Korea. merrygoo@hanmail.net |
3회의 연속된 경막외 스테로이드 주사 후 혈청 혈당치와 코티졸치의 변화 |
김동건, 안현미, 정규영 |
인제대학교 의과대학 부산백병원 재활의학과 |
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Abstract |
Objective To investigate the change of blood glucose and cortisol levels after three consecutive epidural steroid injections Method Fifteen patients with low back pain and radiating pain were included. Three consecutive epidural injections were performed weekly. The serum glucose, insulin and cortisol levels were measured 30 minutes before the 1st injection and at 24 hours and l week after each injection. Results There were significant changes in the result of glucose and insulin levels at 24 hours after each injection (p<0.05), but no signigicant changes at 1 week compared with pre-injection level. The cortisol level significantly decreased at 24 hours after 1st injection and did not return to pre-injection level at 1 week after 1st injection (p<0.05). There were no further increases in the glucose and insulin levels and no further decrease in the cortisol level after each of the three consecutive injections. Conclusion Three consecutive epidural injections at 1 week interval seems to be as safe procedure. But significant suppression of cortisol kept on for 1 week, so it should be taken into account when patients with previous epidural injection undergo major stress. (J Korean Acad Rehab Med 2006; 30: 590-594) |
Key Words:
Epidural steroid injection, Glucose, Insulin, Cortisol, Triamcinolone |
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