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Journal of the Korean Academy of Rehabilitation Medicine 2007;31(1):70-77.
The Therapeutic Effect of Inhibitory Repetitive Transcranial Magnetic Stimulation on Right Inferior Frontal Gyrus in Subcortical Aphasia.
Lee, Ji Hun , Yoo, Woo Kyoung , Jung, Kwang Ik , Kim, Dong Hyun , Park, Dong Sik , Im, Hyoung June
1Department of Rehabilitation Medicine, Hallym University College of Medicine, Korea. wooky@hallym.ac.kr
2Department of Ocupational Medicine, Hallym University College of Medicine, Korea.
피질하 실어증에서 우측 하전두엽 억제 반복 경두개 자기자극의 치료 효과
이지훈, 유우경, 정광익, 김동현, 박동식, 임형준1
한림대학교 의과대학 재활의학교실, 1산업의학교실
Abstract
Objective
To investigate whether suppression of right inferior frontal gyrus (Broca's homologue) by 1 Hz repetitive transcranial magnetic stimulation (rTMS) can improve speech recovery.
Method
We applied low frequency rTMS on right Broca's homologue twice a week for 6 weeks in eight subcortical aphasia patients who were 3 months to 3 years poststroke onset. They were tested with Korean Version-Western Aphasia Battery before and after procedure. Also, they were tested with Parallel Short Forms for the Korean-Boston Naming Test and Animal Naming Test serially for outcome measure. rTMS was performed with intensity of 80% of motor threshold for 10 min (600 pulses) at 1 Hz frequency.
Results
Significant improvement was observed in picture naming at post-rTMS only in nonfluent aphasia patients but not in fluent aphasia patients.
Conclusion
rTMS may provide a novel treatment for aphasia by possibly modulating the distributed, bi-hemispheric language network. (J Korean Acad Rehab Med 2007; 31: 70-77)
Key Words: rTMS, Subcortical aphasia, Inferior frontal lobe, Bi-hemispheric language network


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