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Journal of the Korean Academy of Rehabilitation Medicine 2008;32(5):582-585.
Ipsilateral Corticospinal Projections in a Patient with Bilateral Cortical Malformation: A case report.
Son, Su Min , Park, Sung Hee , Jo, Dae Sun
1Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Korea.
2Department of Physical Medicine and Rehabilitation, Chonbuk National University Medical School, Korea. shpark0130@chonbuk.ac.kr
3Department of Pediatrics and Research Institute of Clinical Medicine, Chonbuk National University Medical School, Korea.
양측 피질 기형을 동반한 환자의 동측 피질척수로 -증례 보고-
손수민, 박성희1, 조대선2
영남대학교 의과대학 재활의학교실, 1전북대학교 의학전문대학원 재활의학교실, 2소아과학교실 및 임상의학연구소
The developing brain is highly plastic and thus brain lesions during development interfere with the innate development of architecture, connectivity and mapping of functions and trigger modifications in structure, wiring and representation. Unilateral inhibition of the sensorimotor cortex during development results in a sparse contralateral projection from this cortex and retention of a greater number of ipsilateral projections from the more active cortex. We report a patient with bilateral cerebral lesions. She had mild hemiparesis. Transcranial magnetic stimulation to the less affected hemisphere elicited bilateral motor evoked potentials of the first dorsal interossei and ipsilateral responses revealed shorter onset latencies and larger peak to peak amplitude than contralateral response, implying a greater ipsilateral than contralateral projection. This observation indicates direct ipsilateral corticospinal projections from the less affected brain hemisphere. (J Korean Acad Rehab Med 2008; 32: 582-585)
Key Words: Corticospinal tract, Development, Plasticity


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