Short Term Effects of Transdermal Scopolamine Patch for Drooling of Saliva in Patients with Cerebral Palsy.

, Roh, Sung Won; , Kim, Chanwoo; , Kim, Taikon; , Lee, Mun Hwan; , Lee, Kyu Hoon

Original Article

Journal of the Korean Academy of Rehabilitation Medicine 2010;34(2):185-188.

Roh, Sung Won , Kim, Chanwoo , Kim, Taikon , Lee, Mun Hwan , Lee, Kyu Hoon

¹Department of Rehabilitation Medicine, Hanyang University College of Medicine, Korea. dumitru1@hanyang.ac.kr
²Jeong Lib O&P, Korea.

뇌성마비 환자의 침흘림에 대한 경피적 스코폴아민 첩포의 단기효과

노성원, 김찬우, 김태곤, 이문환¹, 이규훈

한양대학교 의과대학 재활의학교실, ¹정립보조기

Abstract

Objective
To investigate the clinical usefulness of the transdermal scopolamine patch applied to control drooling of saliva in patients with cerebral palsy.
Method
We enrolled twenty two patients with cerebral palsy residing in a rehabilitation center. The mean age of the patients was 24.0 years old. Transdermal scopolamine patch was applied to the patients for 2 weeks. We measured drooling quantity, severity of drooling, and visual analog scale of care givers' labor intensity at pre-application, post 1 week, and post 2 weeks.
Results
Drooling quantity decreased significantly from 4.1 ±1.9 ml to 2.8±1.5 ml at post 1 week (p＜0.01), and 2.2±1.6 ml at post 2 weeks (p＜0.01). Severity of drooling decreased from 4.1±0.8 to 2.9±1.1 at post 2 weeks (p＜0.01). Visual analog scale of care givers' labor intensity decreased from 78.2±17.4 (mm) to 52.7±18.6 at post 1 week (p＜0.01), and 45.9±22.8 at post 2 weeks (p＜0.01).
Conclusion
These findings suggested that the transdermal scopolamine patch is effective to reduce the drooling of saliva in patients with cerebral palsy within short term. (J Korean Acad Rehab Med 2010; 34: 185-188)

Key Words: Drooling, Saliva, Scopolamine patch