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"Trismus"

Original Article

Effects of Ultrasound, Laser and Exercises on Temporomandibular Joint Pain and Trismus Following Head and Neck Cancer
Hany Mohamed Elgohary, Hadaya Mosaad Eladl, Ashraf Hassan Soliman, Elsadat Saad Soliman
Ann Rehabil Med 2018;42(6):846-853.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.846
Objective
To compare the effects of low intensity ultrasound (LIUS), traditional exercise therapy (TET), low level laser therapy (LLLT) and TET on temporomandibular joint (TMJ) pain and trismus following recovery from head and neck cancer (HNC).
Methods
Sixty participants following, who had experienced HNC, were randomly allocated to three groups of 20 people each. Each group received different therapy. Group A received LIUS and TET; group B received LLLT and TET; while group C received TET. All 60 participants were evaluated under the visual analog scale (VAS), the University of Washington Quality of Life questionnaire (UW-QOL) and the Vernier caliper scale (VCS) at the beginning of the therapies and after 4 weeks.
Results
ANOVA test revealed significant improvements across all three groups with outcomes of p<0.05. The results of the UW-QOL questionnaire showed a significant difference between groups A, B and C in favor of group A (p<0.05). The VAS results showed a more improvement in group A as compared to group B (p<0.05), while there was no statistical difference between groups B and C (p>0.05). The VCS results showed more improvement for the individuals in group B as compared to those in group C (p<0.05), while there was minimal difference between groups A and B (p>0.05).
Conclusion
The LIUS and TET are more effective than LLLT and/or TET in reducing TMJ pain and trismus following HNC.

Citations

Citations to this article as recorded by  
  • Electromyographic evaluation of effectiveness of passive stretch training in patients with temporomandibular disorders and limited mouth opening
    Xiaoyu Lin, Ryota Takaoka, Daisuke Moriguchi, Shion Morioka, You Ueda, Rie Yamamoto, Emi Ono, Shoichi Ishigaki, Masahiro Nishimura
    Scientific Reports.2026;[Epub]     CrossRef
  • Efficiency of different treatment modalities on radiation induced trismus for maxillofacial cases: a parallel randomized clinical trial
    Marwa Ahmed Aboelez, Abdallah Mohammed Ibrahim, Mohammed A ElSawy, Nermeen El sayed El-Khamisy
    BMC Oral Health.2025;[Epub]     CrossRef
  • The synergistic potential of ultrasound and nanomaterials for enhanced diagnosis and therapy of head and neck cancers
    Hua Wang, Yuankun Gao, Dawei Wang, Yulei Wan
    Nanomedicine.2025; 20(15): 1971.     CrossRef
  • The Rationale and Explanation for Rehabilitation Interventions in the Management of Treatment-Induced Trismus in People with Head and Neck Cancer: A Scoping Review of Randomized Controlled Trials
    Ernesto Anarte-Lazo, Ana Bravo-Vazquez, Carlos Bernal-Utrera, Daniel Torres-Lagares, Deborah Falla, Cleofas Rodríguez-Blanco
    Medicina.2025; 61(8): 1392.     CrossRef
  • Rehabilitation strategies for trismus post oral cancer treatment: Progress in the study of mouth opening exercises
    Ling Yang, Guihua Hao, Lili Hou, Wenyu Yang
    Journal of Stomatology, Oral and Maxillofacial Surgery.2024; 125(6): 101796.     CrossRef
  • Assessment of Integrative Therapeutic Methods for Improving the Quality of Life and Functioning in Cancer Patients—A Systematic Review
    Mădălina Gabriela Iliescu, Liliana-Elena Stanciu, Andreea-Bianca Uzun, Adelina-Elena Cristea, Irina Motoască, Laszlo Irsay, Dan Marcel Iliescu, Titus Vari, Alina Deniza Ciubean, Bogdan Marian Caraban, Nicolae Ciufu, Olgun Azis, Viorela Mihaela Ciortea
    Journal of Clinical Medicine.2024; 13(5): 1190.     CrossRef
  • Photobiomodulation combination therapy as a new insight in neurological disorders: a comprehensive systematic review
    Narmin Farazi, Hanieh Salehi-Pourmehr, Fereshteh Farajdokht, Javad Mahmoudi, Saeed Sadigh-Eteghad
    BMC Neurology.2024;[Epub]     CrossRef
  • Exercise adherence for patients with trismus after head and neck cancer treatment
    Emma Charters, Jamie Loy, Ashleigh R. Sharman, Kai Cheng, Masako Dunn, Jonathan Clark
    Head & Neck.2024; 46(11): 2717.     CrossRef
  • A Narrative Review on Pain Management in Head and Neck Cancer: Integrating Multimodal Analgesia and Interventional Procedures
    Farnad Imani, Saleh Mohebbi, Masood Mohseni, Behnaz Karimi, Saeid Rahimi, Gholam Ali Dikafraz Shokooh
    Anesthesiology and Pain Medicine.2024;[Epub]     CrossRef
  • Exercise therapy to treat trismus in a patient with head neck cancer: A case report
    Soumyajit Mandal, Subhajit Mandal, Deepika Malik, Kanika Thakur, Aksh Chahal
    Journal of Society of Indian Physiotherapists.2024; 8(1): 38.     CrossRef
  • Effect of transcutaneous electrical nerve stimulation and Rocabado exercises on temporomandibular joint dysfunction after head and neck surgeries
    Rana M. M. Elattar, Haidy Nady Ashem, Ashraf E. M. Elsebaie, Zeinab A. Ali, Khadra M. Ali
    Fizjoterapia Polska.2024; 24(5): 220.     CrossRef
  • Photobiomodulation therapy for the prevention of acute radiation dermatitis: a systematic review and meta-analysis
    Margherita Gobbo, Victoria Rico, Gustavo Nader Marta, Saverio Caini, Julie Ryan Wolf, Corina van den Hurk, Mara Beveridge, Henry Lam, Pierluigi Bonomo, Edward Chow, Tara Behroozian
    Supportive Care in Cancer.2023;[Epub]     CrossRef
  • Quality assessment of PBM protocols for oral complications in head and neck cancer patients: part 2
    Margherita Gobbo, Praveen R. Arany, Elisabetta Merigo, René-Jean Bensadoun, Alan Roger Santos-Silva, Luiz Alcino Gueiros, Giulia Ottaviani
    Supportive Care in Cancer.2023;[Epub]     CrossRef
  • Effects of a program consisting of strain/counterstrain technique, phonophoresis, heat therapy, and stretching in patients with temporomandibular joint dysfunction
    Insha Azam, Aksh Chahal, Gaurav Kapoor, Pooja Chaudhuri, Ahmad H. Alghadir, Masood Khan, Faizan Z. Kashoo, Vandana Esht, Mohammed M. Alshehri, Mohammad Abu Shaphe, Abdur Raheem Khan, Gurjant Singh
    Medicine.2023; 102(32): e34569.     CrossRef
  • Photobiomodulation therapy in the treatment of radiotherapy-related trismus of the head and neck
    Marcela Maria Fontes Borges, Cássia Emanuella Nóbrega Malta, Anna Clara Aragão Matos Carlos, André Alves Crispim, José Fernando Bastos de Moura, Lievin Matos Rebouças, Bruna Carolina Coelho da Silva, Clarissa Gondim Picanço de Albuquerque, Paulo Goberlâni
    Lasers in Medical Science.2023;[Epub]     CrossRef
  • Ultrasound therapy in the management of temporomandibular joint disorders
    Mohamed Asan, Shruthi Hegde, Babu Subhas, Vidya Ajila, Viabhav Pandita
    Acta stomatologica Naissi.2023; 39(87): 2605.     CrossRef
  • Quality Assessment of PBM Protocols for Oral Complications in Head and Neck Cancer Patients: Part 1
    Margherita Gobbo, Elisabetta Merigo, Praveen R. Arany, René-Jean Bensadoun, Alan Roger Santos-Silva, Luiz Alcino Gueiros, Giulia Ottaviani
    Frontiers in Oral Health.2022;[Epub]     CrossRef
  • Métodos e Técnicas Não Farmacológicos no Tratamento da Dor Oncológica: Revisão Sistemática da Literatura
    Natali dos Santos Nascimento, Amanda Tinôco Neto Santos, Priscila Godoy Januário Martins Alves
    Revista Brasileira de Cancerologia.2022;[Epub]     CrossRef
  • Interventions for Trismus in Head and Neck Cancer Patients: A Systematic Review of Randomized Controlled Trials
    Shuzhen Chee, Yasmeen M. Byrnes, Kevin T. Chorath, Karthik Rajasekaran, Jie Deng
    Integrative Cancer Therapies.2021;[Epub]     CrossRef
  • The outcomes of ultrasonic and laser therapy in case of temporomandibular disorders – an evidence based update
    Marius NEGUCIOIU, Andreea KUI, Mihai MITARIU, Manuela MANZIUC, Daniela CONDOR, Loredana MITARIU, Smaranda BUDURU
    Balneo and PRM Research Journal.2021; 12(3): 210.     CrossRef
  • Role of Manual Therapy for Neck Pain and Quality of Life in Head and Neck Cancer Survivors: A Systematic Review
    Renu B Pattanshetty, Sayali Nandkumar Patil
    Indian Journal of Palliative Care.2021; 28: 99.     CrossRef
  • Interprofessional Collaboration in Dentistry: Role of physiotherapists to improve care and outcomes for chronic pain conditions and sleep disorders
    Alberto Herrero Babiloni, Jacqueline T. A. T. Lam, Fernando G. Exposto, Gabrielle Beetz, Catherine Provost, Dany H. Gagnon, Gilles J. Lavigne
    Journal of Oral Pathology & Medicine.2020; 49(6): 529.     CrossRef
  • Restricted Mouth Opening in Head and Neck Cancer: Etiology, Prevention, and Treatment
    Waseem A. Abboud, Sharon Hassin-Baer, Eran E. Alon, Iris Gluck, Alex Dobriyan, Uri Amit, Ran Yahalom, Noam Yarom
    JCO Oncology Practice.2020; 16(10): 643.     CrossRef
  • 11,242 View
  • 303 Download
  • 18 Web of Science
  • 23 Crossref
Case Reports
Severe Spastic Trismus without Generalized Spasticity after Unilateral Brain Stem Stroke
Jong-Hyun Seo, Don-Kyu Kim, Si Hyun Kang, Kyung-Mook Seo, Ju Won Seok
Ann Rehabil Med 2012;36(1):154-158.   Published online February 29, 2012
DOI: https://doi.org/10.5535/arm.2012.36.1.154

A 62-year-old female patient diagnosed with left brain stem stroke 2 months ago was admitted to our clinic for rehabilitation. She had no generalized spasticity on both extremities, but could open her mouth only approximately 2 mm between her upper and lower teeth due to severe trismus. On needle electromyography, the left masseter muscle showed paradoxically increased muscle activity during mouth opening. We injected 50 units of type A botulinum toxin (Botox®) into the left masseter muscle, and 20 units into the left temporalis muscle with guidance of ultrasonography. The interincisal distance increased to 8 mm on the 3rd day after injection, and 9 mm on the 4th day. One month later, the interincisal distance increased to 14 mm. The increased interincisal distance was maintained for 13 months after injection, and the quality of hygienic care and compliance of oral stimulation therapy also improved.

Citations

Citations to this article as recorded by  
  • Chronic trismus in a cat with an extra-axial mass causing compression of the pons
    Heidi B Thatcher, Joana Tabanez, Victoria Coates, Lorna Arrol
    Journal of Feline Medicine and Surgery Open Reports.2026;[Epub]     CrossRef
  • Botulinum Toxin A in Poststroke Oromandibular Dystonia: Case Reports
    Elena Brevi, Davide Villa, Davide Dalla Costa, Luciana Sciumé, Andrea Cattelan, Dante Facchetti, Giovanna Beretta, Maria Sessa, Isabella Laura Simone
    Case Reports in Neurological Medicine.2026;[Epub]     CrossRef
  • Impact of Hemorrhagic Stroke on Molar Bite Force: A Prospective Study
    Gabriel Pádua da Silva, Edson Donizetti Verri, Marcelo Palinkas, Camila Roza Gonçalves, Paula Napolitano Gonçalves, Robson Felipe Tosta Lopes, Guilherme Gallo Costa Gomes, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo
    Prague Medical Report.2022; 123(3): 181.     CrossRef
  • Handling and progress until achieved oral ingestion against dysphagia of congenital pseudobulbar palsy
    Satoko Yamaguchi, Akiko Ishizaki, Kohji Murakami, Shouji Hironaka
    Pediatric Dental Journal.2021; 31(2): 197.     CrossRef
  • Out of the spasticity box: Off-label uses of botulinum toxin in children
    Joyce L. Oleszek, Amy S. Kanallakan, Aaron J. Powell, Deborah Gaebler-Spira, Michael M. Green
    Journal of Pediatric Rehabilitation Medicine.2020; 13(2): 205.     CrossRef
  • Trismus caused by paraneoplastic brainstem encephalitis
    Naveed Malek, Maxwell Damian
    Practical Neurology.2018; 18(2): 146.     CrossRef
  • Functional outcome of swallowing rehabilitation in 4 dysphagic patients with stroke presenting with dysphonia, severe pseudobulbar palsy, and trismus
    Taro Ogawa
    Nosotchu.2016; 38(5): 319.     CrossRef
  • 7,761 View
  • 48 Download
  • 7 Crossref
Effect of Botulinum Toxin A on Trismus after Traumatic Brain Injury: A case report.
Kang, Youn Joo , Oh, Jun Ho , Kim, Ji Sung , Shin, Sung Hun , Park, Kyung Tae
J Korean Acad Rehabil Med 2008;32(4):456-459.
We report a case of severe trismus following traumatic brain injury (TBI), which was treated successfully with botulinum toxin A. Its effect evidenced long-term resolution, for over one year. A 36 year-old man with a multifocal intracranial hemorrhage was admitted for quadriplegia with dysphagia and trismus. During ten months, a nasogastric tube was placed for feeding after TBI, and at that time his upper- to-lower interincisal distance was only 1.2 cm upon voluntary mouth opening. Botulinum toxin A 450 U (Dysport) was injected into both masseter, medial pterygoid and left temporalis muscles under electromyographic guidance. The interincisal distance began to improve one week after injection. He successfully underwent percutaneous endoscopic gastrostomy, dysphagia rehabilitation therapy, and dental prosthesis. More than one month after injection, oral feeding proved possible. After 1 year his interincisal distance was maintained at 2.9 cm. (J Korean Acad Rehab Med 2008; 32: 456-459)
  • 2,155 View
  • 30 Download
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