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Review Article

Spinal cord injury

Robot-Assisted Gait Training in Individuals With Spinal Cord Injury: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Jong Mi Park, Yong Wook Kim, Su Ji Lee, Ji Cheol Shin
Ann Rehabil Med 2024;48(3):171-191.   Published online June 28, 2024
DOI: https://doi.org/10.5535/arm.230039
Spinal cord injury (SCI) rehabilitation emphasizes locomotion. Robotic-assisted gait training (RAGT) is widely used in clinical settings because of its benefits; however, its efficacy remains controversial. We conducted a systematic review and meta-analysis to investigate the efficacy of RAGT in patients with SCI. We searched international and domestic databases for articles published until April 18, 2024. The meta-analysis employed a random effects model to determine the effect size as either mean difference (MD) or standardized MD (SMD). Evidence quality was evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Twenty-three studies with a total of 690 participants were included in the final analysis. The overall pooled effect size for improvement in activities of daily living was 0.24, with SMD (95% confidence interval [95% CI], 0.04–0.43; GRADE: high) favoring RAGT over conventional rehabilitation. Muscular strength (MD, 0.23; 95% CI, 0.02–0.44; GRADE: high), walking index for SCI (MD, 0.31; 95% CI, 0.07–0.55; GRADE: moderate) and 6 min walk test distance (MD, 0.38; 95% CI, 0.14–0.63; GRADE: moderate) showed significant improvement in the robot group. Subgroup analysis revealed that subacute patients and intervention periods >2 months were more effective. This meta-analysis revealed that RAGT significantly improved activities of daily living, muscular strength, and walking abilities. Additional studies are needed to identify the optimal treatment protocol and specific patient groups for which the protocol is most effective.

Citations

Citations to this article as recorded by  
  • Effects of Unpredictable Perturbation Training on a Split-Belt Treadmill on Physical Performance in Older Adults: A Randomized Controlled Trial
    Kap-Soo Han, Myoung-Hwan Ko
    Geriatrics.2025; 10(1): 23.     CrossRef
  • Advances and New Therapies in Traumatic Spinal Cord Injury
    Antonio Montoto-Marqués, Jesús Benito-Penalva, María Elena Ferreiro-Velasco, Mark Andrew Wright, Sebastian Salvador-De la Barrera, Hatice Kumru, Nelson Gaitán-Pérez, Agustin Hernández-Navarro, Antonio Rodríguez-Sotillo, Fernando Martins Braga, Angela Pale
    Journal of Clinical Medicine.2025; 14(7): 2203.     CrossRef
  • Factors influencing on functional independence outcomes after hospitalization and rehabilitation in children with spinal cord injury
    Hong-Bo Zhao, Xiang-Jiang Rong, Qi Zhang, Ting-Ting Ma, He Yan, Tian-Tian Zhou, Yan-Qing Zhang
    BMC Pediatrics.2025;[Epub]     CrossRef
  • 4,981 View
  • 153 Download
  • 3 Web of Science
  • 3 Crossref
Original Articles

Brain disorders

Feasibility and Usability of a Robot-Assisted Complex Upper and Lower Limb Rehabilitation System in Patients with Stroke: A Pilot Study
Kyoung Tae Kim, Yongmin Choi, Jang Hyuk Cho, Soyoung Lee
Ann Rehabil Med 2023;47(2):108-117.   Published online April 30, 2023
DOI: https://doi.org/10.5535/arm.23017
Objective
To evaluate the feasibility and usability of cost-effective complex upper and lower limb robot-assisted gait training in patients with stroke using the GTR-A, a foot-plate based end-effector type robotic device.
Methods
Patients with subacute stroke (n=9) were included in this study. The enrolled patients received 30-minute robot-assisted gait training thrice a week for 2 weeks (6 sessions). The hand grip strength, functional ambulation categories, modified Barthel index, muscle strength test sum score, Berg Balance Scale, Timed Up and Go Test, and Short Physical Performance Battery were used as functional assessments. The heart rate was measured to evaluate cardiorespiratory fitness. A structured questionnaire was used to evaluate the usability of robot-assisted gait training. All the parameters were evaluated before and after the robot-assisted gait training program.
Results
Eight patients completed robot-assisted gait training, and all parameters of functional assessment significantly improved between baseline and posttraining, except for hand grip strength and muscle strength test score. The mean scores for each domain of the questionnaire were as follows: safety, 4.40±0.35; effects, 4.23±0.31; efficiency, 4.22±0.77; and satisfaction, 4.41±0.25.
Conclusion
Thus, the GTR-A is a feasible and safe robotic device for patients with gait impairment after stroke, resulting in improvement of ambulatory function and performance of activities of daily living with endurance training. Further research including various diseases and larger sample groups is necessary to verify the utility of this device.

Citations

Citations to this article as recorded by  
  • Changes in body composition, physical fitness and quality of life on robotic gait assisted training in patients with Guillain-Barré Syndrome: a case report
    Moon Jin Lee, Sung Jin Yoon
    Physical Activity and Nutrition.2024; 28(4): 009.     CrossRef
  • Smart Devices for Health and Wellness Applied to Tele-Exercise: An Overview of New Trends and Technologies Such as IoT and AI
    Antonio Fabbrizio, Alberto Fucarino, Manuela Cantoia, Andrea De Giorgio, Nuno D. Garrido, Enzo Iuliano, Victor Machado Reis, Martina Sausa, José Vilaça-Alves, Giovanna Zimatore, Carlo Baldari, Filippo Macaluso
    Healthcare.2023; 11(12): 1805.     CrossRef
  • 5,063 View
  • 114 Download
  • 1 Web of Science
  • 2 Crossref
Effects of Combined Upper Limb Robotic Therapy in Patients With Tetraplegic Spinal Cord Injury
Joo Hwan Jung, Hye Jin Lee, Duk Youn Cho, Jung-Eun Lim, Bum Suk Lee, Seung Hyun Kwon, Hae Young Kim, Su Jeong Lee
Ann Rehabil Med 2019;43(4):445-457.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.445
Objective
To confirm the effects of combined upper limb robotic therapy (RT) as compared to conventional occupational therapy (OT) in tetraplegic spinal cord injury (SCI) patients and to suggest the optimized treatment guidelines of combined upper limb RT.
Methods
After subject recruitment and screening for eligibility, the baseline evaluation for outcome measures were performed. We evaluated the Graded and Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP), the American Spinal Injury Association upper extremity motor score, grip and pinch strength, and the Spinal Cord Independence Measurement III (SCIM-III). In this study, the pre-tested participants were divided randomly into the RT and OT group. The utilized interventions included combined upper limb RT using ArmeoPower and Amadeo (RT group), or conventional OT (OT group) in addition to daily inpatient rehabilitation program. The participants underwent 40 minutes×3 sessions×5 weeks of interventions.
Results
A total of 30 tetraplegic SCI patients completed entire study program. After 5 weeks of intervention, both groups demonstrated increases in GRASSP-strength and SCIM-III. The manual muscle test scores of elbow flexion, elbow extension, 2-5th metacarpophalangeal extension, and SCIM-III subscores of bathing-upper, dressing-upper, and grooming as well as the GRASSP-qualitative prehension score were noted to have been significantly increased in the RT group as evaluated. The OT group showed improvements in the GRASSP-quantitative prehension score and some items in grip and pinch strength. There was no significant difference between the two groups in almost all measurements except for the SCIM-III bathing-upper subscore.
Conclusion
Combined upper limb RT demonstrated beneficial effects on the upper limb motor function in patients with tetraplegic SCI, which were comparable with conventional OT.

Citations

Citations to this article as recorded by  
  • Anxiety and Depression in Pediatric-Onset Traumatic Spinal Cord Injury: A Systematic Review
    Mohammad Mofatteh, Mohammad Sadegh Mashayekhi, Saman Arfaie, Yimin Chen, Armaan K. Malhotra, Georgios P. Skandalakis, Mohammed Ali Alvi, Fardad T. Afshari, Shakila Meshkat, Famu Lin, Ebtesam Abdulla, Ayush Anand, Xuxing Liao, Roger S. McIntyre, Carlo Sant
    World Neurosurgery.2024; 184: 267.     CrossRef
  • Technology-Assisted Upper Limb Therapy (TAULT): Evaluation of Clinical Practice at a Specialised Centre for Spinal Cord Injury in Switzerland
    Daniela B. Kuchen, Beatrice Hubacher, Andris Ladner, Inge-Marie Velstra, Mario Widmer
    Healthcare.2023; 11(23): 3055.     CrossRef
  • Reliability Validity and Responsiveness of the Spinal Cord Independence Measure 4th Version in a Multicultural Setup
    Amiram Catz, Malka Itzkovich, Keren Elkayam, Dianne Michaeli, Ilana Gelernter, Yoav Benjamini, Harvinder Singh Chhabra, Luigi Tesio, Einat Engel-Haber, Emiliana Bizzarini, Claudio Pilati, Giulio Del Popolo, Ilaria Baroncini, Nan Liu, Paulo Margalho, Thaba
    Archives of Physical Medicine and Rehabilitation.2022; 103(3): 430.     CrossRef
  • Donor activation focused rehabilitation approach to hand closing nerve transfer surgery in individuals with cervical level spinal cord injury
    Lorna C. Kahn, Adam G. Evans, Elspeth J. R. Hill, Ida K. Fox
    Spinal Cord Series and Cases.2022;[Epub]     CrossRef
  • The Impact of Robotic Therapy on the Self-Perception of Upper Limb Function in Cervical Spinal Cord Injury: A Pilot Randomized Controlled Trial
    V. Lozano-Berrio, M. Alcobendas-Maestro, B. Polonio-López, A. Gil-Agudo, A. de la Peña-González, A. de los Reyes-Guzmán
    International Journal of Environmental Research and Public Health.2022; 19(10): 6321.     CrossRef
  • The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications
    Carmen Delia Nistor-Cseppento, Anamaria Gherle, Nicoleta Negrut, Simona Gabriela Bungau, Anca Maria Sabau, Andrei-Flavius Radu, Alexa Florina Bungau, Delia Mirela Tit, Bogdan Uivaraseanu, Timea Claudia Ghitea, Diana Uivarosan
    Medicina.2022; 58(10): 1447.     CrossRef
  • LncRNA Airsci increases the inflammatory response after spinal cord injury in rats through the nuclear factor kappa B signaling pathway
    Tao Zhang, Kang Li, Zi-Lu Zhang, Kai Gao, Chao-Liang Lv
    Neural Regeneration Research.2021; 16(4): 772.     CrossRef
  • Do any physiotherapy interventions increase spinal cord independence measure or functional independence measure scores in people with spinal cord injuries? A systematic review
    Lisa A. Harvey, Joanne V. Glinsky, Jackie Chu
    Spinal Cord.2021; 59(7): 705.     CrossRef
  • Design and Performance Evaluation of a Hybrid Hand Exoskeleton for Hand Opening/Closing
    Muhammad Ahsan Gull, Shaoping Bai, Jakob Udby Blicher, Tobias Glaston Staermose
    Journal of Medical Devices.2021;[Epub]     CrossRef
  • Upper Limb Robotic Rehabilitation for Patients with Cervical Spinal Cord Injury: A Comprehensive Review
    Giovanni Morone, Alessandro de Sire, Alex Martino Cinnera, Matteo Paci, Luca Perrero, Marco Invernizzi, Lorenzo Lippi, Michela Agostini, Irene Aprile, Emanuela Casanova, Dario Marino, Giuseppe La Rosa, Federica Bressi, Silvia Sterzi, Daniele Giansanti, Al
    Brain Sciences.2021; 11(12): 1630.     CrossRef
  • Clinical efficacy ofMajoon FalasfaandRoghan-e-Surkhin post-stroke-disability: an open labeled, pre-post analysis
    Izhar Ahmad, Tanzeel Ahmad, Mohd Aleemuddin Quamri
    Drug Metabolism and Drug Interactions.2021; 36(1): 41.     CrossRef
  • Clinical efficacy ofMajoon FalasfaandRoghan-e-Surkhin post-stroke-disability: an open labeled, pre-post analysis
    Izhar Ahmad, Tanzeel Ahmad, Mohd Aleemuddin Quamri
    Drug Metabolism and Personalized Therapy.2020;[Epub]     CrossRef
  • 13,120 View
  • 450 Download
  • 10 Web of Science
  • 12 Crossref
Effect of Combined Therapy of Robot and Low-Frequency Repetitive Transcranial Magnetic Stimulation on Hemispatial Neglect in Stroke Patients
Sang Beom Kim, Kyeong Woo Lee, Jong Hwa Lee, Sook Joung Lee, Jin Gee Park, Joung Bok Lee
Ann Rehabil Med 2018;42(6):788-797.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.788
Objective
To investigate the effect of upper limb rehabilitation combining robot with low-frequency repetitive transcranial magnetic stimulation (rTMS) on unilateral spatial neglect in stroke patients.
Methods
Patients who had hemispatial neglect after right hemisphere stroke were randomly divided into rTMS only group, robot only group, and combined group. All groups received conventional neglect therapy and additional treatment for each group. rTMS group received rTMS therapy. Robot group received robot therapy, while combined group received both therapies. The effect of therapy was assessed with Motor-Free Visual Perception Test-3 (MVPT-3), line bisection test, star cancellation test, Catherine Bergego Scale (CBS), Mini-Mental State Examination (MMSE), and the Korean version of Modified Barthel Index (K-MBI). These measurements were evaluated before and after treatment.
Results
For each group, 10 patients were recruited. There were no significant differences in baseline characteristics or initial values among the three groups. Two weeks after the therapy, all groups showed significant improvement in MVPT-3, line bisection test, star cancellation test, CBS, MMSE, and K-MBI. However, changes in measurements showed no significant differences among groups.
Conclusion
Treatment effect of the combined therapy of robotic therapy and low-frequency rTMS therapy for hemispatial neglect was not statistically different from that of each single treatment. Results of this study did not prove the superiority of any of the three treatments. Further study with large number of patients is needed to evaluate the superiority of these treatments.

Citations

Citations to this article as recorded by  
  • Repetitive transcranial magnetic stimulation for cognitive rehabilitation in stroke survivors: A systematic review and meta-analysis of randomized controlled trials
    Anas R. Alashram
    Applied Neuropsychology: Adult.2025; : 1.     CrossRef
  • Comparative efficacy of non-invasive brain stimulation for post-stroke cognitive impairment: a network meta-analysis
    Mengyu Yan, Jiarui Liu, Yiming Guo, Qingtao Hou, Jiaqi Song, Xiaoqin Wang, Weihua Yu, Yang Lü
    Aging Clinical and Experimental Research.2024;[Epub]     CrossRef
  • Efficacy of rTMS in treating functional impairment in post-stroke patients: a systematic review and meta-analysis
    Xiaodong Duan, Delong Huang, Haoshu Zhong, Junhao Wu, Zhihan Xiao, Peng Yang, Yuanhang Han, Haodong Jiang, Ping Zhou, Xi Liu
    Neurological Sciences.2024; 45(8): 3887.     CrossRef
  • Does repetitive transcranial magnetic stimulation have a beneficial effect on improving unilateral spatial neglect caused by stroke? A meta-analysis
    Ruixuan Lin, Jack Jiaqi Zhang, Lingling Zhong, Sofina S. Y. Chan, Patrick W. H. Kwong, Lukas Lorentz, Usman Jawed Shaikh, Tommy L. H. Lam, David M. A. Mehler, Kenneth N. K. Fong
    Journal of Neurology.2024; 271(10): 6494.     CrossRef
  • A Review on Combined Strategy of Non-invasive Brain Stimulation and Robotic Therapy
    Leiyu Zhang, Yawei Chang, Feiran Zhang, Jianfeng Li
    Chinese Journal of Mechanical Engineering.2024;[Epub]     CrossRef
  • Recent advances in treatment of spatial neglect: networks and neuropsychology
    Alex R. Carter, A.M. Barrett
    Expert Review of Neurotherapeutics.2023; 23(7): 587.     CrossRef
  • Current trends in the treatment of patients with post-stroke unilateral spatial neglect: a scoping review
    Chuka Umeonwuka, Ronel Roos, Veronica Ntsiea
    Disability and Rehabilitation.2022; 44(11): 2158.     CrossRef
  • Effect of Robot-Assisted Training on Unilateral Spatial Neglect After Stroke: Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Rodrigo Bazan, Bruno Henrique de Souza Fonseca, Jessica Mariana de Aquino Miranda, Hélio Rubens de Carvalho Nunes, Silméia Garcia Zanati Bazan, Gustavo José Luvizutto
    Neurorehabilitation and Neural Repair.2022; 36(8): 545.     CrossRef
  • A Complex Intervention Integrating Prism Adaptation and Neck Vibration for Unilateral Neglect in Patients of Chronic Stroke: A Randomised Controlled Trial
    Hyun-Se Choi, Bo-Min Lee
    International Journal of Environmental Research and Public Health.2022; 19(20): 13479.     CrossRef
  • Systematic review and network meta-analysis of effects of noninvasive brain stimulation on post-stroke cognitive impairment
    Yueying Wang, Ning Xu, Runfang Wang, Weiyi Zai
    Frontiers in Neuroscience.2022;[Epub]     CrossRef
  • Neglect syndrome in post-stroke conditions: assessment and treatment (scoping review)
    Ibolya Tavaszi, Alexandra Szilvia Nagy, Gabor Szabo, Gabor Fazekas
    International Journal of Rehabilitation Research.2021; 44(1): 3.     CrossRef
  • The effects of robot-assisted left-hand training on hemispatial neglect in older patients with chronic stroke
    Jin-Hyuck Park
    Medicine.2021; 100(9): e24781.     CrossRef
  • Non-pharmacological interventions for spatial neglect or inattention following stroke and other non-progressive brain injury
    Verity Longley, Christine Hazelton, Calvin Heal, Alex Pollock, Kate Woodward-Nutt, Claire Mitchell, Gorana Pobric, Andy Vail, Audrey Bowen
    Cochrane Database of Systematic Reviews.2021;[Epub]     CrossRef
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    Giovanni Morone, Ilaria Cocchi, Stefano Paolucci, Marco Iosa
    Expert Review of Medical Devices.2020; 17(3): 223.     CrossRef
  • 8,350 View
  • 200 Download
  • 14 Web of Science
  • 14 Crossref
Effect of Robot-Assisted Game Training on Upper Extremity Function in Stroke Patients
Kyeong Woo Lee, Sang Beom Kim, Jong Hwa Lee, Sook Joung Lee, Jin Wan Kim
Ann Rehabil Med 2017;41(4):539-546.   Published online August 31, 2017
DOI: https://doi.org/10.5535/arm.2017.41.4.539
Objective

To determine the effects of combining robot-assisted game training with conventional upper extremity rehabilitation training (RCT) on motor and daily functions in comparison with conventional upper extremity rehabilitation training (OCT) in stroke patients.

Methods

Subjects were eligible if they were able to perform the robot-assisted game training and were divided randomly into a RCT and an OCT group. The RCT group performed one daily session of 30 minutes of robot-assisted game training with a rehabilitation robot, plus one daily session of 30 minutes of conventional rehabilitation training, 5 days a week for 2 weeks. The OCT group performed two daily sessions of 30 minutes of conventional rehabilitation training. The effects of training were measured by a Manual Function Test (MFT), Manual Muscle Test (MMT), Korean version of the Modified Barthel Index (K-MBI) and a questionnaire about satisfaction with training. These measurements were taken before and after the 2-week training.

Results

Both groups contained 25 subjects. After training, both groups showed significant improvements in motor and daily functions measured by MFT, MMT, and K-MBI compared to the baseline. Both groups demonstrated similar training effects, except motor power of wrist flexion. Patients in the RCT group were more satisfied than those in the OCT group.

Conclusion

There were no significant differences in changes in most of the motor and daily functions between the two types of training. However, patients in the RCT group were more satisfied than those in the OCT group. Therefore, RCT could be a useful upper extremity rehabilitation training method.

Citations

Citations to this article as recorded by  
  • Quantifying patient experiences with therapeutic neurorehabilitation technologies: a scoping review
    Chi Mai Nguyen, Jeric Uy, Ines Serrada, Brenton Hordacre
    Disability and Rehabilitation.2024; 46(9): 1662.     CrossRef
  • Human Understanding and Perception of Unanticipated Robot Action in the Context of Physical Interaction
    Naoko Abe, Yue Hu, Mehdi Benallegue, Natsuki Yamanobe, Gentiane Venture, Eiichi Yoshida
    ACM Transactions on Human-Robot Interaction.2024; 13(1): 1.     CrossRef
  • Effectiveness of an Intensive, Functional, and Gamified Rehabilitation Program on Upper Limb Function in People With Stroke (EnteRtain): A Multicenter Randomized Clinical Trial
    A. Sulfikar Ali, D. Senthil Kumaran, Amritha Unni, Sanjukta Sardesai, Vasudeva Prabhu, Punitha Nirmal, Aparna R. Pai, Vasudeva Guddattu, Ashokan Arumugam
    Neurorehabilitation and Neural Repair.2024; 38(4): 243.     CrossRef
  • Therapeutic robots for post-stroke rehabilitation
    Ronghua Hong, Bingyu Li, Yunjun Bao, Lingyu Liu, Lingjing Jin
    Medical Review.2024; 4(1): 55.     CrossRef
  • A study on the intention of upper limb hemiplegic patients to use interactive gaming devices for hand rehabilitation
    Chujun Yang, Chih-Fu Wu, Jingyan Wang, Wen-Chi Chen, Haoyen Chang, Dan Dan Xu
    The Design Journal.2024; 27(3): 470.     CrossRef
  • The efficacy of virtual reality for upper limb rehabilitation in stroke patients: a systematic review and meta-analysis
    Mohsen Soleimani, Marjan Ghazisaeedi, Soroush Heydari
    BMC Medical Informatics and Decision Making.2024;[Epub]     CrossRef
  • Effects of virtual reality in the early-stage stroke rehabilitation: A systematic review and meta-analysis of randomized controlled trials
    Jie Hao, Zixuan Yao, Kimberly Harp, Dr. Yeongjin Gwon, Zhen Chen, Ka-Chun Siu
    Physiotherapy Theory and Practice.2023; 39(12): 2569.     CrossRef
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    Yu Zhu, Chen Wang, Jin Li, Liqing Zeng, Peizhen Zhang
    Frontiers in Neurology.2023;[Epub]     CrossRef
  • Will Your Next Therapist Be a Robot?—A Review of the Advancements in Robotic Upper Extremity Rehabilitation
    Raouf Fareh, Ammar Elsabe, Mohammed Baziyad, Tunajjina Kawser, Brahim Brahmi, Mohammad H. Rahman
    Sensors.2023; 23(11): 5054.     CrossRef
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    Chenli Lin, Yuanyuan Ren, Aming Lu
    Neurosurgical Review.2023;[Epub]     CrossRef
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    Yue Hu, Naoko Abe, Mehdi Benallegue, Natsuki Yamanobe, Gentiane Venture, Eiichi Yoshida
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    Federica Bressi, Laura Cricenti, Benedetta Campagnola, Marco Bravi, Sandra Miccinilli, Fabio Santacaterina, Silvia Sterzi, Sofia Straudi, Michela Agostini, Matteo Paci, Emanuela Casanova, Dario Marino, Giuseppe La Rosa, Daniele Giansanti, Luca Perrero, Al
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    Bianca Chinembiri, Zhang Ming, Shang Kai, Zhang Xiu Fang, Chen Wei
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    Giulia Monardo, Chiara Pavese, Ines Giorgi, Marco Godi, Roberto Colombo
    Games for Health Journal.2021; 10(1): 13.     CrossRef
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    Thais Tavares Terranova, Marcel Simis, Artur César Aquino Santos, Fábio Marcon Alfieri, Marta Imamura, Felipe Fregni, Linamara Rizzo Battistella
    Frontiers in Neurorobotics.2021;[Epub]     CrossRef
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    Yue Hu, Mehdi Benallegue, Gentiane Venture, Eiichi Yoshida
    IEEE Robotics and Automation Letters.2020; 5(4): 6764.     CrossRef
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    Ji-Su Park, Gihyoun Lee, Jong-Bae Choi, Na-Kyoung Hwang, Young-Jin Jung
    NeuroRehabilitation.2019; 45(2): 221.     CrossRef
  • Effects of Combined Upper Limb Robotic Therapy in Patients With Tetraplegic Spinal Cord Injury
    Joo Hwan Jung, Hye Jin Lee, Duk Youn Cho, Jung-Eun Lim, Bum Suk Lee, Seung Hyun Kwon, Hae Young Kim, Su Jeong Lee
    Annals of Rehabilitation Medicine.2019; 43(4): 445.     CrossRef
  • 10,021 View
  • 130 Download
  • 20 Web of Science
  • 19 Crossref
Feasibility of Rehabilitation Training With a Newly Developed, Portable, Gait Assistive Robot for Balance Function in Hemiplegic Patients
Junhyun Sung, Sehoon Choi, Hyunbae Kim, Gyuhan Lee, Changsoo Han, Younghoon Ji, Dongbin Shin, Seunghoon Hwang, Deokwon Yun, Hyeyoun Jang, Mi Jung Kim
Ann Rehabil Med 2017;41(2):178-187.   Published online April 27, 2017
DOI: https://doi.org/10.5535/arm.2017.41.2.178
Objective

To investigate the clinical feasibility of a newly developed, portable, gait assistive robot (WA-H, ‘walking assist for hemiplegia’) for improving the balance function of patients with stroke-induced hemiplegia.

Methods

Thirteen patients underwent 12 weeks of gait training on the treadmill while wearing WA-H for 30 minutes per day, 4 days a week. Patients' balance function was evaluated by the Berg Balance Scale (BBS), Fugl-Meyer Assessment Scale (FMAS), Timed Up and Go Test (TUGT), and Short Physical Performance Battery (SPPB) before and after 6 and 12 weeks of training.

Results

There were no serious complications or clinical difficulties during gait training with WA-H. In three categories of BBS, TUGT, and the balance scale of SPPB, there was a statistically significant improvement at the 6th week and 12th week of gait training with WA-H. In the subscale of balance function of FMAS, there was statistically significant improvement only at the 12th week.

Conclusion

Gait training using WA-H demonstrated a beneficial effect on balance function in patients with hemiplegia without a safety issue.

Citations

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  • The role of lower limb exoskeletons in rehabilitation: a scoping review
    Philip Abery, Elisa F.D. Canetti, Wayne Hing
    Physical Therapy Reviews.2025; 30(2): 118.     CrossRef
  • Gait Performance and Brain Activity Are Improved by Gait Automatization during Robot-Assisted Gait Training in Patients with Burns: A Prospective, Randomized, Single-Blinded Study
    Seung Yeol Lee, Jisu Seo, Cheong Hoon Seo, Yoon Soo Cho, So Young Joo
    Journal of Clinical Medicine.2024; 13(16): 4838.     CrossRef
  • Perceptions of using exoskeleton technology among physiotherapists and stroke survivors in Malaysia: a mixed methods study
    Devinder Kaur Ajit Singh, Deepashini Harithasan, Aiman Mat Najib, Muhammad Shafiq Ishak, Rizauddin Ramli
    Disability and Rehabilitation: Assistive Technology.2024; : 1.     CrossRef
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    Hossein B. Khaniki, Mergen H. Ghayesh, Rey Chin, Marco Amabili
    International Journal of Non-Linear Mechanics.2023; 148: 104275.     CrossRef
  • Development of a Wearable Upper Limb Rehabilitation Robot Based on Reinforced Soft Pneumatic Actuators
    Xinbo Chen, Shuai Zhang, Kaibin Cao, Chunjie Wei, Wumian Zhao, Jiantao Yao
    Chinese Journal of Mechanical Engineering.2022;[Epub]     CrossRef
  • Robotic Home-Based Rehabilitation Systems Design: From a Literature Review to a Conceptual Framework for Community-Based Remote Therapy During COVID-19 Pandemic
    Aylar Akbari, Faezeh Haghverd, Saeed Behbahani
    Frontiers in Robotics and AI.2021;[Epub]     CrossRef
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    So Young Joo, Seung Yeol Lee, Yoon Soo Cho, Kuem Ju Lee, Sang-Hyun Kim, Cheong Hoon Seo
    Computer Methods in Biomechanics and Biomedical Engineering.2020; 23(12): 888.     CrossRef
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    So Young Joo, Seung Yeol Lee, Yoon Soo Cho, Kuem Ju Lee, Cheong Hoon Seo
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Improved Gait Speed After Robot-Assisted Gait Training in Patients With Motor Incomplete Spinal Cord Injury: A Preliminary Study
Seungwon Hwang, Hye-Ri Kim, Zee-A Han, Bum-Suk Lee, Soojeong Kim, Hyunsoo Shin, Jae-Gun Moon, Sung-Phil Yang, Mun-Hee Lim, Duk-Youn Cho, Hayeon Kim, Hye-Jin Lee
Ann Rehabil Med 2017;41(1):34-41.   Published online February 28, 2017
DOI: https://doi.org/10.5535/arm.2017.41.1.34
Objective

To evaluate the clinical features that could serve as predictive factors for improvement in gait speed after robotic treatment.

Methods

A total of 29 patients with motor incomplete spinal cord injury received 4-week robot-assisted gait training (RAGT) on the Lokomat (Hocoma AG, Volketswil, Switzerland) for 30 minutes, once a day, 5 times a week, for a total of 20 sessions. All subjects were evaluated for general characteristics, the 10-Meter Walk Test (10MWT), the Lower Extremity Motor Score (LEMS), the Functional Ambulatory Category (FAC), the Walking Index for Spinal Cord Injury version II (WISCI-II), the Berg Balance Scale (BBS), and the Spinal Cord Independence Measure version III (SCIM-III) every 0, and 4 weeks. After all the interventions, subjects were stratified using the 10MWT score at 4 weeks into improved group and non-improved group for statistical analysis.

Results

The improved group had younger age and shorter disease duration than the non-improved group. All subjects with the American Spinal Injury Association Impairment Scale level C (AIS-C) tetraplegia belonged to the non-improved group, while most subjects with AIS-C paraplegia, AIS-D tetraplegia, and AIS-D paraplegia belonged to the improved group. The improved group showed greater baseline lower extremity strength, balance, and daily living function than the non-improved group.

Conclusion

Assessment of SCIM-III, BBS, and trunk control, in addition to LEMS, have potential for predicting the effects of robotic treatment in patients with motor incomplete spinal cord injury.

Citations

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  • The Effect of Assistive Robotic Technologies on Quality of Life and Functional Independence in Individuals with Spinal Cord Injury
    Abdurrahim Yıldız, Rüstem Mustafaoğlu, Nur Kesiktaş
    Journal of Basic and Clinical Health Sciences.2024; 8(3): 580.     CrossRef
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    Isabella Fabbri, Fabio Betti, Roberto Tedeschi
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  • Clinical Utility of Robot-Assisted Gait Training in Patients with Spinal Cord Injury Caused by Electrical Burns: A Case Report
    Seung-Yeol Lee, Cheong-Hoon Seo, Yoon-Soo Cho, So-Young Joo
    Journal of Clinical Medicine.2023; 12(23): 7220.     CrossRef
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    Florian van Dellen, Rob Labruyère
    Journal of NeuroEngineering and Rehabilitation.2022;[Epub]     CrossRef
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    Juntaek Hong, Jongweon Lee, Taeyoung Choi, Wooin Choi, Taeyong Kim, Kyuwan Kwak, Seongjun Kim, Kyeongyeol Kim, Daehyun Kim
    Sensors.2022; 22(10): 3870.     CrossRef
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    Denniss Raigoso, Nathalia Céspedes, Carlos A. Cifuentes, Antonio J. del-Ama, Marcela Múnera
    Brain Sciences.2021; 11(6): 738.     CrossRef
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The Effect of an Upper Limb Rehabilitation Robot on Hemispatial Neglect in Stroke Patients
Yoon Sik Choi, Kyeong Woo Lee, Jong Hwa Lee, Sang Beom Kim, Gyu Tae Park, Sook Joung Lee
Ann Rehabil Med 2016;40(4):611-619.   Published online August 24, 2016
DOI: https://doi.org/10.5535/arm.2016.40.4.611
Objective

To investigate the effectiveness of an upper limb rehabilitation robot therapy on hemispatial neglect in stroke patients.

Methods

Patients were randomly divided into an upper limb rehabilitation robot treatment group (robot group) and a control group. The patients in the robot group received left upper limb training using an upper limb rehabilitation robot. The patients sat on the right side of the robot, so that the monitor of the robot was located on the patients' left side. In this position, patients could focus continuously on the left side. The control group received conventional neglect treatment, such as visual scanning training and range of motion exercises, administered by occupational therapists. Both groups received their respective therapies for 30 minutes a day, 5 days a week for 3 weeks. Several tests were used to evaluate treatment effects before and after the 3-week treatment.

Results

In total, 38 patients (20 in the robot group and 18 in the control group) completed the study. After completion of the treatment sessions, both groups showed significant improvements in the Motor-Free Visual Perception Test 3rd edition (MVPT-3), the line bisection test, the star cancellation test, the Albert's test, the Catherine Bergego scale, the Mini-Mental State Examination and the Korean version of Modified Barthel Index. The changes in all measurements showed no significant differences between the two groups.

Conclusion

This present study showed that the upper limb robot treatment had benefits for hemispatial neglect in stroke patients that were similar to conventional neglect treatment. The upper limb robot treatment could be a therapeutic option in the treatment of hemispatial neglect after stroke.

Citations

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Effect of Robotic-Assisted Gait Training in Patients With Incomplete Spinal Cord Injury
Ji Cheol Shin, Ji Yong Kim, Han Kyul Park, Na Young Kim
Ann Rehabil Med 2014;38(6):719-725.   Published online December 24, 2014
DOI: https://doi.org/10.5535/arm.2014.38.6.719
Objective

To determine the effect of robotic-assisted gait training (RAGT) compared to conventional overground training.

Methods

Sixty patients with motor incomplete spinal cord injury (SCI) were included in a prospective, randomized clinical trial by comparing RAGT to conventional overground training. The RAGT group received RAGT three sessions per week at duration of 40 minutes with regular physiotherapy in 4 weeks. The conventional group underwent regular physiotherapy twice a day, 5 times a week. Main outcomes were lower extremity motor score of American Spinal Injury Association impairment scale (LEMS), ambulatory motor index (AMI), Spinal Cord Independence Measure III mobility section (SCIM3-M), and walking index for spinal cord injury version II (WISCI-II) scale.

Results

At the end of rehabilitation, both groups showed significant improvement in LEMS, AMI, SCIM3-M, and WISCI-II. Based on WISCI-II, statistically significant improvement was observed in the RAGT group. For the remaining variables, no difference was found.

Conclusion

RAGT combined with conventional physiotherapy could yield more improvement in ambulatory function than conventional therapy alone. RAGT should be considered as one additional tool to provide neuromuscular reeducation in patient with incomplete SCI.

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Plantar Pressure Distribution During Robotic-Assisted Gait in Post-stroke Hemiplegic Patients
Jin Kyu Yang, Na El Ahn, Dae Hyun Kim, Deog Young Kim
Ann Rehabil Med 2014;38(2):145-152.   Published online April 29, 2014
DOI: https://doi.org/10.5535/arm.2014.38.2.145
Objective

To assess the plantar pressure distribution during the robotic-assisted walking, guided through normal symmetrical hip and knee physiological kinematic trajectories, with unassisted walking in post-stroke hemiplegic patients.

Methods

Fifteen hemiplegic stroke patients, who were able to walk a minimum of ten meters independently but with asymmetric gait patterns, were enrolled in this study. All the patients performed both the robotic-assisted walking (Lokomat) and the unassisted walking on the treadmill with the same body support in random order. The contact area, contact pressure, trajectory length of center of pressure (COP), temporal data on both limbs and asymmetric index of both limbs were obtained during both walking conditions, using the F-Scan in-shoe pressure measurement system.

Results

The contact area of midfoot and total foot on the affected side were significantly increased in robotic-assisted walking as compared to unassisted walking (p<0.01). The contact pressure of midfoot and total foot on affected limbs were also significantly increased in robotic-assisted walking (p<0.05). The anteroposterior and mediolateral trajectory length of COP were not significantly different between the two walking conditions, but their trajectory variability of COP was significantly improved (p<0.05). The asymmetric index of area, stance time, and swing time during robotic-assisted walking were statistically improved as compared with unassisted walking (p<0.05).

Conclusion

The robotic-assisted walking may be helpful in improving the gait stability and symmetry, but not the physiologic ankle rocker function.

Citations

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