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"Recurrence"

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"Recurrence"

Original Articles

Cardiopulmonary rehabilitation

Objective
We conducted a systematic review and meta-analysis to analyze the effects of cardiac rehabilitation (CR) on post-discharge prognoses of patients with acute myocardial infarction (AMI).
Methods
A literature search was conducted through four international medical and two Korean databases. Primary outcomes for the effectiveness of CR included all-cause mortality, cardiovascular mortality, recurrence, revascularization, major adverse cardiovascular event, major adverse cardiocerebrovascular event, and readmission. We summarized and analyzed results of studies about CR for AMI, including not only randomized controlled trials (RCTs) but also non-RCTs. We calculated the effect size separately by the study type.
Results
Fourteen articles were finally selected. Of these, two articles were RCTs, while 12 were non-RCTs. In RCTs, the overall mortality rate was lower in the group that participated in CR than that in the conventional care group by 28% (relative risk=0.72; 95% confidence interval, 0.34–1.57). Among non-RCTs, CR participation significantly decreased the overall risk of mortality. Moreover, the rates of recurrence and major adverse cardiovascular events were lower in the group that participated in CR compared to those in the non-CR group.
Conclusion
The meta-analysis shows that CR reduces the risk of re-hospitalization and all-cause mortality after AMI, compared to no participation in CR. This outcome was seen in RCTs as well as in non-RCTs. More studies are necessary for concrete conclusions about the beneficial effects of CR after AMI in various settings.

Citations

Citations to this article as recorded by  
  • A Cross-Sectional Examination of Sex-Based Differences in Cardiac Rehabilitation Participation From the Behavioral Risk Factor Surveillance System
    Shweta Gore, Amol M. Karmarkar, Lin-Na Chou, Sabrina J. Mily, Amit Kumar
    Journal of Cardiopulmonary Rehabilitation and Prevention.2026; 46(3): 204.     CrossRef
  • A journey map for improving the cardiac rehabilitation experience and care quality of patients with coronary heart disease: A longitudinal qualitative study
    Lushuang Yuan, Yao Li, Xiujie Jiang, Zhen Yang
    International Journal of Nursing Studies.2026; 178: 105390.     CrossRef
  • Medical rehabilitation and health resort treatment in patients with cardiovascular diseases
    V. V. Shipulin
    Journal of Medical Rehabilitation.2026; 4(2): 167.     CrossRef
  • Comparison of Inpatient and Outpatient Cardiac Rehabilitation Following Myocardial Infarction
    Piotr Jankowski, Roman Topór-Mądry, Paweł Kozieł, Daniel Cieśla, Urszula Cegłowska, Monika Burzyńska, Zbigniew Eysymontt, Radosław Sierpiński, Jarosław Pinkas, Mariusz Gąsior
    Journal of Clinical Medicine.2025; 14(9): 3007.     CrossRef
  • The mediating role of physical activity self-efficacy between knowledge, psychological factors, and early physical activity in elderly post-PCI patients: a cross-sectional study
    Haoran Gao, Jun Liu, Jiuxin Zhou, Yujie Zhou, Ke Song, Su Lyu, Xiao Yang, Yuanmei Qin
    BMC Geriatrics.2025;[Epub]     CrossRef
  • Feasibility and Effects of a Home-Based Cardiac Telerehabilitation Program Following Coronary Intervention: A pilot study
    Min Soo Lim, Ju Yeon Lee, So Jung Lee, Youngjee Jeon
    The Journal of Korean Physical Therapy.2025; 37(6): 329.     CrossRef
  • A Detailed Analysis of Cardiac Rehabilitation on 180-Day All-Cause Hospital Readmission and Mortality
    Brian D. Duscha, Leanna M. Ross, Andrew L. Hoselton, Lucy W. Piner, Carl F. Pieper, William E. Kraus
    Journal of Cardiopulmonary Rehabilitation and Prevention.2024; 44(2): 99.     CrossRef
  • Impact of Cardiac Rehabilitation Health Insurance Coverage on Cardiac Rehabilitation Use in Korea Using an Interrupted Time Series
    Yu Shin Park, In Sun Song, Suk‐Yong Jang, Chung Mo Nam, Eun‐Cheol Park
    Journal of the American Heart Association.2024;[Epub]     CrossRef
  • Predischarge oxygen uptake efficiency slope has short and long-term value in the prognosis of patients after acute myocardial infarction
    Sheng-Hui Tuan, Jin-Hui Chung, Yi-Ju Tsai, Wei-Chun Huang, Guan-Bo Chen, Yun-Jeng Tsai, Ko-Long Lin
    Journal of the Chinese Medical Association.2024; 87(4): 414.     CrossRef
  • Clinical effects of training programs in cardiac rehabilitation. Experience from different countries
    D. M. Aronov, M. G. Bubnova
    Cardiovascular Therapy and Prevention.2024; 23(2): 3936.     CrossRef
  • A Systematic Review of the Completion of Cardiac Rehabilitation Programs for Adults Aged 18-50 Years
    Anna K. Jansson, Tracy L. Schumacher, Lucy Kocanda, Megan Whatnall, Matthew Fenwick, Dimity Betts, Adrian Bauman, Jane Kerr, Mitch J. Duncan, Clare E. Collins, Andrew Boyle, Kerry J. Inder, Ronald C. Plotnikoff
    Journal of Cardiopulmonary Rehabilitation and Prevention.2024; 44(5): E30.     CrossRef
  • Effect of a patient health engagement (PHE) model on rehabilitation participation in patients with acute myocardial infarction after PCI: a study protocol for a randomized controlled trial
    Zixian Liu, Guangfang Zhang, Xiaolei Liang, Dechun Qin
    Trials.2024;[Epub]     CrossRef
  • Cost-effectiveness of metacognitive therapy for cardiac rehabilitation participants with symptoms of anxiety and/or depression: analysis of a randomised controlled trial
    Gemma E Shields, Elizabeth Camacho, Linda M Davies, Patrick Joseph Doherty, David Reeves, Lora Capobianco, Anthony Heagerty, Calvin Heal, Deborah Buck, Adrian Wells
    BMJ Open.2024; 14(12): e087414.     CrossRef
  • Adaptation and validation of the cardiovascular version of the Return-to-Work Obstacles and Self-Efficacy Scale (ROSES-CVD) to the Italian context
    Andrea Gragnano, Marc Corbière, Eleonora Picco, Alessia Negrini, Gaia Savioli, Massimo Conti, Luca Corsiglia, Massimo Miglioretti
    Disability and Rehabilitation.2023; 45(21): 3573.     CrossRef
  • Financial InceNtives for cArdiac rehabilitatioN ComplEtion (FINANCE) (single blind pragmatic RCT)
    Jae In Lee, Jae-Young Han, Hae-Bin Gwak, Chang-Won Moon, Min Kyun Sohn, Sungju Jee, Chul Kim
    Medicine.2023; 102(8): e32936.     CrossRef
  • Fact Sheet on Cardiac Rehabilitation for Cardiovascular Disease in South Korea
    Ki-Hong Kim, Jae-Young Han
    Annals of Rehabilitation Medicine.2023; 47(5): 318.     CrossRef
  • Impact of cardiac rehabilitation on cardiovascular event in Korea
    In Sun Song, Yu shin Park, Suk-Yong Jang, Jung Mo Nam, Chan Joo Lee, Eun-Cheol Park
    Scientific Reports.2023;[Epub]     CrossRef
  • Effects of Home-Based Baduanjin Exercise on Left Ventricular Remodeling in Patients With Acute Anterior ST-Segment Elevation Myocardial Infarction: Study Protocol for a Randomized Controlled Trial
    Yinhe Cai, Liang Kang, Haiyi Li, Yuan Luo, Junmao Wen, Zhaohui Gong, Qingmin Chu, Yijun Qiu, Chuanjin Luo, Keyu Chen, Xinjun Zhao, Rong Li
    Frontiers in Cardiovascular Medicine.2022;[Epub]     CrossRef
  • Current Status of Cardiac Rehabilitation in the Regional Cardiocerebrovascular Centers in Korea
    Chul Kim, Jidong Sung, Jae-Young Han, Sungju Jee, Jang Woo Lee, Jong Hwa Lee, Won-Seok Kim, Heui Je Bang, Sora Baek, Kyung-Lim Joa, Ae Ryoung Kim, So Young Lee, Jihee Kim, Chung Reen Kim, Oh Pum Kwon
    Journal of Clinical Medicine.2021; 10(21): 5079.     CrossRef
  • Public Health Rehabilition after Acute Myocardial Infarction: a Randomized Controlled Study
    Damira G. Zhamankulova, Lazzat M. Zhamaliyeva, Gulnara L. Kurmanalina, Ziyash Tanbetova, Andrey M. Grjibovski
    Ekologiya cheloveka (Human Ecology).2021; 28(8): 57.     CrossRef
  • 11,952 View
  • 197 Download
  • 18 Web of Science
  • 20 Crossref
Prognostic Influences of Cardiac Rehabilitation in Korean Acute Myocardial Infarction Patients
Chul Kim, Duk You Kim, Chang Jin Moon
Ann Rehabil Med 2011;35(3):375-380.   Published online June 30, 2011
DOI: https://doi.org/10.5535/arm.2011.35.3.375
Objective

To observe the prognostic influences of the cardiac rehabilitation (CR) program in Korean acute myocardial infarction (AMI) patients during the first year after an occurrence of the disease.

Method

A total of 141 AMI patients who underwent percutaneous coronary intervention (PCI) were recruited consecutively for this study and divided into the CR group and the control group. The CR group completed the phase 2 CR program in the hospital for a period of 6-8 weeks and maintained self-exercise in their community by exercise prescription for a year after AMI. We performed a prospective comparison of the patients' demographic data, high sensitive C-reactive protein (hs-CRP) level after the 4-month CR program, and the rate of recurrence (AMI, re-hospitalization, positive coronary angiogram, needed revascularization procedure, or death) between the two groups.

Results

Compared to the control group (0.33±0.48 mg/dl), the hs-CRP level was lower in the CR group (0.18±0.32 mg/dl) after 4 months of exercise. The recurrence rate was lower (10%, 7/69) in the CR group, compared to the control group (24%, 17/72, p<0.05). The number of disease-free days was larger in the CR group (354±38.34), compared to the control group (316±99.96, p<0.05). In a comparison of statistical methods used for testing the equality of two survivor distributions, the CR group showed a lower recurrence rate than the control group (p<0.05).

Conclusion

Participation in the CR program designed for AMI patients who underwent PCI-induced normalization of the serum hs-CRP level and lowering of the recurrence rate by 14% during the first year.

Citations

Citations to this article as recorded by  
  • Causal Model Building in the Context of Cardiac Rehabilitation: A Systematic Review
    Nilufar Akbari, Georg Heinze, Geraldine Rauch, Ben Sander, Heiko Becher, Daniela Dunkler
    International Journal of Environmental Research and Public Health.2023; 20(4): 3182.     CrossRef
  • Do Cardiac Rehabilitation Affect Clinical Prognoses Such as Recurrence, Readmission, Revascularization, and Mortality After AMI?: Systematic Review and Meta-Analysis
    Chul Kim, Insun Choi, Songhee Cho, Ae Ryoung Kim, Wonseok Kim, Sungju Jee
    Annals of Rehabilitation Medicine.2021; 45(1): 57.     CrossRef
  • Effect of exercise training on left ventricular remodeling in patients with myocardial infarction and possible mechanisms
    Meng Cai, Lei Wang, Yan-Long Ren
    World Journal of Clinical Cases.2021; 9(22): 6308.     CrossRef
  • Exercise-based cardiac rehabilitation for coronary heart disease
    Grace Dibben, James Faulkner, Neil Oldridge, Karen Rees, David R Thompson, Ann-Dorthe Zwisler, Rod S Taylor
    Cochrane Database of Systematic Reviews.2021;[Epub]     CrossRef
  • Effectiveness of comprehensive cardiac rehabilitation in coronary artery disease patients treated according to contemporary evidence based medicine: Update of the Cardiac Rehabilitation Outcome Study (CROS-II)
    Annett Salzwedel, Katrin Jensen, Bernhard Rauch, Patrick Doherty, Maria-Inti Metzendorf, Matthes Hackbusch, Heinz Völler, Jean-Paul Schmid, Constantinos H Davos
    European Journal of Preventive Cardiology.2020; 27(16): 1756.     CrossRef
  • Cardiac rehabilitation and 5-year mortality after acute myocardial infarction. Report from 11 tertiary hospitals in Korea (ETHIK Study)
    Chul KIM, Insun CHOI, Songhee CHO, Jae-Young HAN, Ae-Ryoung KIM, Won-Seok KIM, Sungju JEE, Jong H. LEE, Min C. JOO, Heui J. BANG, Kyung-Lim JOA, Eun Y. HAN, Sora BAEK, Jung-Im SHIM, Jin A. CHOI
    European Journal of Physical and Rehabilitation Medicine.2020;[Epub]     CrossRef
  • Clinical Practice Guideline for Cardiac Rehabilitation in Korea
    Chul Kim, Jidong Sung, Jong Hwa Lee, Won-Seok Kim, Goo Joo Lee, Sungju Jee, Il-Young Jung, Ueon Woo Rah, Byung Ok Kim, Kyoung Hyo Choi, Bum Sun Kwon, Seung Don Yoo, Heui Je Bang, Hyung-Ik Shin, Yong Wook Kim, Heeyoune Jung, Eung Ju Kim, Jung Hwan Lee, In
    Annals of Rehabilitation Medicine.2019; 43(3): 355.     CrossRef
  • Clinical Practice Guideline for Cardiac Rehabilitation in Korea
    Chul Kim, Jidong Sung, Jong Hwa Lee, Won-Seok Kim, Goo Joo Lee, Sungju Jee, Il-Young Jung, Ueon Woo Rah, Byung Ok Kim, Kyoung Hyo Choi, Bum Sun Kwon, Seung Don Yoo, Heui Je Bang, Hyung-Ik Shin, Yong Wook Kim, Heeyoune Jung, Eung Ju Kim, Jung Hwan Lee, In
    The Korean Journal of Thoracic and Cardiovascular Surgery.2019; 52(4): 248.     CrossRef
  • Clinical Practice Guideline for Cardiac Rehabilitation in Korea: Recommendations for Cardiac Rehabilitation and Secondary Prevention after Acute Coronary Syndrome
    Chul Kim, Jidong Sung, Jong Hwa Lee, Won-Seok Kim, Goo Joo Lee, Sungju Jee, Il-Young Jung, Ueon Woo Rah, Byung Ok Kim, Kyoung Hyo Choi, Bum Sun Kwon, Seung Don Yoo, Heui Je Bang, Hyung-Ik Shin, Yong Wook Kim, Heeyoune Jung, Eung Ju Kim, Jung Hwan Lee, In
    Korean Circulation Journal.2019; 49(11): 1066.     CrossRef
  • Mobilization of Patients Suffering from Acute Myocardial Infarction – When Is It Too Early?
    Diana Opincariu, Roxana Hodas
    Journal Of Cardiovascular Emergencies.2019; 5(3): 99.     CrossRef
  • The effectiveness of modern cardiac rehabilitation: A systematic review of recent observational studies in non-attenders versus attenders
    Jennifer Sumner, Alexander Harrison, Patrick Doherty, Yih-Kuen Jan
    PLOS ONE.2017; 12(5): e0177658.     CrossRef
  • Inpatient cardiac rehabilitation programs’ exercise therapy for patients undergoing cardiac surgery: National Korean Questionnaire Survey
    Yong Gon Seo, Mi Ja Jang, Won Hah Park, Kyung Pyo Hong, Jidong Sung
    Journal of Exercise Rehabilitation.2017; 13(1): 76.     CrossRef
  • The prognostic effect of cardiac rehabilitation in the era of acute revascularisation and statin therapy: A systematic review and meta-analysis of randomized and non-randomized studies – The Cardiac Rehabilitation Outcome Study (CROS)
    Bernhard Rauch, Constantinos H Davos, Patrick Doherty, Daniel Saure, Maria-Inti Metzendorf, Annett Salzwedel, Heinz Völler, Katrin Jensen, Jean-Paul Schmid
    European Journal of Preventive Cardiology.2016; 23(18): 1914.     CrossRef
  • Exercise-based cardiac rehabilitation for coronary heart disease
    Lindsey Anderson, David R Thompson, Neil Oldridge, Ann-Dorthe Zwisler, Karen Rees, Nicole Martin, Rod S Taylor
    Cochrane Database of Systematic Reviews.2016;[Epub]     CrossRef
  • Changes of high sensitivity C-reactive protein during clopidogrel therapy in patients undergoing percutaneous coronary intervention
    Shokoufeh Hajsadeghi, Mandana Chitsazan, Mitra Chitsazan, Negar Salehi, Ahmad Amin, Majid Maleki, Nima Babaali, Seifollah Abdi, Maryam Mohsenian
    Research in Cardiovascular Medicine.2016; 5(1): 3.     CrossRef
  • 6,938 View
  • 63 Download
  • 15 Crossref
Risk Factors Associated with Stroke Recurrence.
Kim, Moo Kyum , Kang, Min Jeong , Lee, Hoan Nyoung , Lee, Kyoung Min
J Korean Acad Rehabil Med 2000;24(5):857-863.

Objective: This study was done to evaluate the risk factors associated with recurrence after first-ever stroke.

Method: We retrospectively studied 256 first-ever stroke patients treated in Dong-Eui hospital from March 1997 to February 1998. Telephone or out-patient interviews were performed with these patients regarding stroke recurrence and treatment for hypertension and diabetes mellitus. These were divided into two groups, those with recurrence and those without. Evaluated risk factors for stroke recurrence were the following: history of diabetes mellitus, hypertension, heart disease, smoking, alcohol drinking, and transient ischemic attack; clinical findings at admission of hypertension, diabetes mellitus, hyperlipidemia, heart disease, type and location of stroke; treatment compliance for diabetes mellitus and hypertension after discharge.

Results: The recurrence rate after first-ever stroke was 12.9%. In univariate analysis, significant risk factors for stroke recurrence were history of smoking, clinical findings at admission of diabetes mellitus, atrial fibrillation, ischemic heart disease, and non-compliance with therapy for diabetes mellitus and hypertension after discharge (p<0.05). In multivariate analysis, significant risk factors for stroke recurrence were atrial fibrillation at admission (odds ratio=3.43) and non-compliance with therapy for hypertension after discharge (odds ratio=7.51)(p<0.05).

Conclusion: History of smoking, clinical findings at admission of diabetes mellitus, atrial fibrillation, ischemic heart disease, and non-compliance with therapy for diabetes mellitus and hypertension after discharge are considered to be important factors for recurrence of stroke. So treatment and education for those factors associated with stroke recurrence are needed during rehabilitation program.

  • 2,144 View
  • 26 Download
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