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"Perceptual disorders"

Original Articles
Relationship Between Line Bisection Test Time and Hemispatial Neglect Prognosis in Patients With Stroke: A Prospective Pilot Study
Shinyoung Kwon, Wookyung Park, MinYoung Kim, Jong Moon Kim
Ann Rehabil Med 2020;44(4):292-300.   Published online August 5, 2020
DOI: https://doi.org/10.5535/arm.19112
Objective
To determine the relationship between line bisection test (LBT) performance time and prognosis of hemispatial neglect (HSN) in stroke patients.
Methods
Data on stroke patients with HSN were prospectively collected. After patient recruitment and eligibility screening, the LBT, Motor-Free Visual Perception Test 3rd edition, and Korean version of Mini-Mental State Examination were performed at the time of admission and 4 weeks thereafter. The LBT performance time was also measured. All patients received conventional rehabilitation for 4 weeks. Based on the improvements in their LBT grades, the patients were divided into improved and non-improved groups. The evaluation results of the two groups were compared using Mann–Whitney U-tests and logistic regression was performed to predict the independence of each outcome.
Results
In total, 26 stroke patients with HSN were included, with 13 patients in each group. Significant differences were observed in the baseline LBT performance times between the improved and non-improved groups (p<0.05). Logistic regression analysis revealed associations between HSN prognosis, and baseline LBT performance time (odds ratio=0.95; 95% confidence interval, 0.90–1.00; p<0.05) and baseline Motor-Free Visual Perception Test 3rd edition (odds ratio=1.20; 95% confidence interval, 1.01–1.43; p<0.05).
Conclusion
A significant relationship was observed between the baseline LBT performance time and HSN prognosis.

Citations

Citations to this article as recorded by  
  • Application of immersive virtual reality for assessing chronic neglect in individuals with stroke: the immersive virtual road-crossing task
    Julia Belger, Sebastian Wagner, Michael Gaebler, Hans-Otto Karnath, Bernhard Preim, Patrick Saalfeld, Anna Schatz, Arno Villringer, Angelika Thöne-Otto
    Journal of Clinical and Experimental Neuropsychology.2024; 46(3): 254.     CrossRef
  • Preservation of Cerebellar Afferent Pathway May Be Related to Good Hand Function in Patients with Stroke
    Bo Kyung Shin, Hae-Yeon Park, Hanee Rim, Ji Yoon Jung, Sungwoo Paek, Yeun Jie Yoo, Mi-Jeong Yoon, Bo Young Hong, Seong Hoon Lim
    Life.2022; 12(7): 959.     CrossRef
  • 7,623 View
  • 219 Download
  • 4 Web of Science
  • 2 Crossref
Effect of Combined Therapy of Robot and Low-Frequency Repetitive Transcranial Magnetic Stimulation on Hemispatial Neglect in Stroke Patients
Sang Beom Kim, Kyeong Woo Lee, Jong Hwa Lee, Sook Joung Lee, Jin Gee Park, Joung Bok Lee
Ann Rehabil Med 2018;42(6):788-797.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.788
Objective
To investigate the effect of upper limb rehabilitation combining robot with low-frequency repetitive transcranial magnetic stimulation (rTMS) on unilateral spatial neglect in stroke patients.
Methods
Patients who had hemispatial neglect after right hemisphere stroke were randomly divided into rTMS only group, robot only group, and combined group. All groups received conventional neglect therapy and additional treatment for each group. rTMS group received rTMS therapy. Robot group received robot therapy, while combined group received both therapies. The effect of therapy was assessed with Motor-Free Visual Perception Test-3 (MVPT-3), line bisection test, star cancellation test, Catherine Bergego Scale (CBS), Mini-Mental State Examination (MMSE), and the Korean version of Modified Barthel Index (K-MBI). These measurements were evaluated before and after treatment.
Results
For each group, 10 patients were recruited. There were no significant differences in baseline characteristics or initial values among the three groups. Two weeks after the therapy, all groups showed significant improvement in MVPT-3, line bisection test, star cancellation test, CBS, MMSE, and K-MBI. However, changes in measurements showed no significant differences among groups.
Conclusion
Treatment effect of the combined therapy of robotic therapy and low-frequency rTMS therapy for hemispatial neglect was not statistically different from that of each single treatment. Results of this study did not prove the superiority of any of the three treatments. Further study with large number of patients is needed to evaluate the superiority of these treatments.

Citations

Citations to this article as recorded by  
  • Repetitive transcranial magnetic stimulation for cognitive rehabilitation in stroke survivors: A systematic review and meta-analysis of randomized controlled trials
    Anas R. Alashram
    Applied Neuropsychology: Adult.2025; : 1.     CrossRef
  • European Stroke Organisation (ESO) guideline on visual impairment in stroke
    Fiona J Rowe, Lauren R Hepworth, María Begoña Coco-Martin, Celine R Gillebert, Luis Leal-Vega, Anja Palmowski-Wolfe, Eleni Papageorgiou, Stephen James Ryan, Karolina Skorkovska, Anne Hege Aamodt
    European Stroke Journal.2025;[Epub]     CrossRef
  • Emerging trends and research hotspots of non-invasive brain stimulation for stroke: a bibliometric and visualization study
    Zhengyu Li, Xi Zhao, Siyu Xie, Wenying Shi, Wei Zhang
    Frontiers in Neurology.2025;[Epub]     CrossRef
  • Comparative efficacy of non-invasive brain stimulation for post-stroke cognitive impairment: a network meta-analysis
    Mengyu Yan, Jiarui Liu, Yiming Guo, Qingtao Hou, Jiaqi Song, Xiaoqin Wang, Weihua Yu, Yang Lü
    Aging Clinical and Experimental Research.2024;[Epub]     CrossRef
  • Efficacy of rTMS in treating functional impairment in post-stroke patients: a systematic review and meta-analysis
    Xiaodong Duan, Delong Huang, Haoshu Zhong, Junhao Wu, Zhihan Xiao, Peng Yang, Yuanhang Han, Haodong Jiang, Ping Zhou, Xi Liu
    Neurological Sciences.2024; 45(8): 3887.     CrossRef
  • Does repetitive transcranial magnetic stimulation have a beneficial effect on improving unilateral spatial neglect caused by stroke? A meta-analysis
    Ruixuan Lin, Jack Jiaqi Zhang, Lingling Zhong, Sofina S. Y. Chan, Patrick W. H. Kwong, Lukas Lorentz, Usman Jawed Shaikh, Tommy L. H. Lam, David M. A. Mehler, Kenneth N. K. Fong
    Journal of Neurology.2024; 271(10): 6494.     CrossRef
  • A Review on Combined Strategy of Non-invasive Brain Stimulation and Robotic Therapy
    Leiyu Zhang, Yawei Chang, Feiran Zhang, Jianfeng Li
    Chinese Journal of Mechanical Engineering.2024;[Epub]     CrossRef
  • Recent advances in treatment of spatial neglect: networks and neuropsychology
    Alex R. Carter, A.M. Barrett
    Expert Review of Neurotherapeutics.2023; 23(7): 587.     CrossRef
  • Current trends in the treatment of patients with post-stroke unilateral spatial neglect: a scoping review
    Chuka Umeonwuka, Ronel Roos, Veronica Ntsiea
    Disability and Rehabilitation.2022; 44(11): 2158.     CrossRef
  • Effect of Robot-Assisted Training on Unilateral Spatial Neglect After Stroke: Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Rodrigo Bazan, Bruno Henrique de Souza Fonseca, Jessica Mariana de Aquino Miranda, Hélio Rubens de Carvalho Nunes, Silméia Garcia Zanati Bazan, Gustavo José Luvizutto
    Neurorehabilitation and Neural Repair.2022; 36(8): 545.     CrossRef
  • A Complex Intervention Integrating Prism Adaptation and Neck Vibration for Unilateral Neglect in Patients of Chronic Stroke: A Randomised Controlled Trial
    Hyun-Se Choi, Bo-Min Lee
    International Journal of Environmental Research and Public Health.2022; 19(20): 13479.     CrossRef
  • Systematic review and network meta-analysis of effects of noninvasive brain stimulation on post-stroke cognitive impairment
    Yueying Wang, Ning Xu, Runfang Wang, Weiyi Zai
    Frontiers in Neuroscience.2022;[Epub]     CrossRef
  • Neglect syndrome in post-stroke conditions: assessment and treatment (scoping review)
    Ibolya Tavaszi, Alexandra Szilvia Nagy, Gabor Szabo, Gabor Fazekas
    International Journal of Rehabilitation Research.2021; 44(1): 3.     CrossRef
  • The effects of robot-assisted left-hand training on hemispatial neglect in older patients with chronic stroke
    Jin-Hyuck Park
    Medicine.2021; 100(9): e24781.     CrossRef
  • Non-pharmacological interventions for spatial neglect or inattention following stroke and other non-progressive brain injury
    Verity Longley, Christine Hazelton, Calvin Heal, Alex Pollock, Kate Woodward-Nutt, Claire Mitchell, Gorana Pobric, Andy Vail, Audrey Bowen
    Cochrane Database of Systematic Reviews.2021;[Epub]     CrossRef
  • Robot-assisted therapy for arm recovery for stroke patients: state of the art and clinical implication
    Giovanni Morone, Ilaria Cocchi, Stefano Paolucci, Marco Iosa
    Expert Review of Medical Devices.2020; 17(3): 223.     CrossRef
  • 8,620 View
  • 201 Download
  • 15 Web of Science
  • 16 Crossref
The Effect of an Upper Limb Rehabilitation Robot on Hemispatial Neglect in Stroke Patients
Yoon Sik Choi, Kyeong Woo Lee, Jong Hwa Lee, Sang Beom Kim, Gyu Tae Park, Sook Joung Lee
Ann Rehabil Med 2016;40(4):611-619.   Published online August 24, 2016
DOI: https://doi.org/10.5535/arm.2016.40.4.611
Objective

To investigate the effectiveness of an upper limb rehabilitation robot therapy on hemispatial neglect in stroke patients.

Methods

Patients were randomly divided into an upper limb rehabilitation robot treatment group (robot group) and a control group. The patients in the robot group received left upper limb training using an upper limb rehabilitation robot. The patients sat on the right side of the robot, so that the monitor of the robot was located on the patients' left side. In this position, patients could focus continuously on the left side. The control group received conventional neglect treatment, such as visual scanning training and range of motion exercises, administered by occupational therapists. Both groups received their respective therapies for 30 minutes a day, 5 days a week for 3 weeks. Several tests were used to evaluate treatment effects before and after the 3-week treatment.

Results

In total, 38 patients (20 in the robot group and 18 in the control group) completed the study. After completion of the treatment sessions, both groups showed significant improvements in the Motor-Free Visual Perception Test 3rd edition (MVPT-3), the line bisection test, the star cancellation test, the Albert's test, the Catherine Bergego scale, the Mini-Mental State Examination and the Korean version of Modified Barthel Index. The changes in all measurements showed no significant differences between the two groups.

Conclusion

This present study showed that the upper limb robot treatment had benefits for hemispatial neglect in stroke patients that were similar to conventional neglect treatment. The upper limb robot treatment could be a therapeutic option in the treatment of hemispatial neglect after stroke.

Citations

Citations to this article as recorded by  
  • Swarm-initialized adaptive controller with beetle antenna searching of wearable lower limb exoskeleton for sit-to-stand and walking motions
    Mohammad Soleimani Amiri, Rizauddin Ramli, Mien Van
    ISA Transactions.2025; 158: 640.     CrossRef
  • European Stroke Organisation (ESO) guideline on visual impairment in stroke
    Fiona J Rowe, Lauren R Hepworth, María Begoña Coco-Martin, Celine R Gillebert, Luis Leal-Vega, Anja Palmowski-Wolfe, Eleni Papageorgiou, Stephen James Ryan, Karolina Skorkovska, Anne Hege Aamodt
    European Stroke Journal.2025;[Epub]     CrossRef
  • Effect of Robot-Assisted Training on Unilateral Spatial Neglect After Stroke: Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Rodrigo Bazan, Bruno Henrique de Souza Fonseca, Jessica Mariana de Aquino Miranda, Hélio Rubens de Carvalho Nunes, Silméia Garcia Zanati Bazan, Gustavo José Luvizutto
    Neurorehabilitation and Neural Repair.2022; 36(8): 545.     CrossRef
  • Combined virtual reality and haptic robotics induce space and movement invariant sensorimotor adaptation
    Meytal Wilf, Mouna Cerra Cheraka, Max Jeanneret, Renaud Ott, Henri Perrin, Sonia Crottaz-Herbette, Andrea Serino
    Neuropsychologia.2021; 150: 107692.     CrossRef
  • The effects of robot-assisted left-hand training on hemispatial neglect in older patients with chronic stroke
    Jin-Hyuck Park
    Medicine.2021; 100(9): e24781.     CrossRef
  • Neglect syndrome in post-stroke conditions: assessment and treatment (scoping review)
    Ibolya Tavaszi, Alexandra Szilvia Nagy, Gabor Szabo, Gabor Fazekas
    International Journal of Rehabilitation Research.2021; 44(1): 3.     CrossRef
  • Non-pharmacological interventions for spatial neglect or inattention following stroke and other non-progressive brain injury
    Verity Longley, Christine Hazelton, Calvin Heal, Alex Pollock, Kate Woodward-Nutt, Claire Mitchell, Gorana Pobric, Andy Vail, Audrey Bowen
    Cochrane Database of Systematic Reviews.2021;[Epub]     CrossRef
  • Robot-Assisted Arm Training in Stroke Individuals With Unilateral Spatial Neglect: A Pilot Study
    Ze-Jian Chen, Ming-Hui Gu, Chang He, Cai-Hua Xiong, Jiang Xu, Xiao-Lin Huang
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • Robot Diagnosis Test for Egocentric and Allocentric Hemineglect
    Vincenza Montedoro, Marie Alsamour, Stéphanie Dehem, Thierry Lejeune, Bruno Dehez, Martin G Edwards
    Archives of Clinical Neuropsychology.2019; 34(4): 481.     CrossRef
  • Pushing attention to one side: Force field adaptation alters neural correlates of orienting and disengagement of spatial attention
    Eva‐Maria Reuter, Jason B. Mattingley, Ross Cunnington, Stephan Riek, Timothy J. Carroll
    European Journal of Neuroscience.2019; 49(1): 120.     CrossRef
  • Effects of robot assistive upper extremity rehabilitation on motor and cognitive recovery, the quality of life, and activities of daily living in stroke patients
    Derya Zengin-Metli, Sibel Özbudak-Demir, İrem Eraktaş, Vildan Binay-Safer, Timur Ekiz
    Journal of Back and Musculoskeletal Rehabilitation.2018; 31(6): 1059.     CrossRef
  • Effect of Combined Therapy of Robot and Low-Frequency Repetitive Transcranial Magnetic Stimulation on Hemispatial Neglect in Stroke Patients
    Sang Beom Kim, Kyeong Woo Lee, Jong Hwa Lee, Sook Joung Lee, Jin Gee Park, Joung Bok Lee
    Annals of Rehabilitation Medicine.2018; 42(6): 788.     CrossRef
  • Upper limb robotics applied to neurorehabilitation: An overview of clinical practice
    Christophe Duret, Stefano Mazzoleni, Hermano Igo Krebs
    NeuroRehabilitation.2017; 41(1): 5.     CrossRef
  • Recovery of Proprioception in the Upper Extremity by Robotic Mirror Therapy: a Clinical Pilot Study for Proof of Concept
    Hyung Seok Nam, Sukgyu Koh, Jaewon Beom, Yoon Jae Kim, Jang Woo Park, Eun-sil Koh, Sun Gun Chung, Sungwan Kim
    Journal of Korean Medical Science.2017; 32(10): 1568.     CrossRef
  • The effects of cognitive versus motor demands on postural performance and weight bearing asymmetry in patients with stroke
    Hossein Negahban, Masoome Ebrahimzadeh, Mohammad Mehravar
    Neuroscience Letters.2017; 659: 75.     CrossRef
  • 7,266 View
  • 161 Download
  • 18 Web of Science
  • 15 Crossref
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