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Case Report

Cervical Spine Malformations Associated With a 5q34-5q35.2 Micro-interstitial Deletion: A Case Report
Heewon Lee, Joon Sung Kim, Seong Hoon Lim, Bomi Sul, Bo Young Hong
Ann Rehabil Med 2018;42(6):884-887.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.884
We report a female proband carrying a de novo 5q34-q35.2 deletion breakpoint, and review the unique skeletal phenotype and possible genotype related to this mutation. The patient presented with a persistent head tilt and limited head rotation. Non-contrast-enhanced three-dimensional computed tomography of the cervical spine revealed several malformations including a bone cleft in the right pars interarticularis, a bone defect in both C5 lamina and the transverse foramen at C2–C3, agenesis of the right articular process of C5, bony fusion of C4–C5, and subluxation of the craniocervical joints. Several deformities of the cervical spine seen in this patient have not been associated with the 5q deletion. A review of 5q-related mutations suggests that abnormalities associated with MSX2 gene might cause cervical spine abnormalities.
  • 7,917 View
  • 90 Download

Original Articles

A New Instrument for Measuring Tibial Torsion in Pediatric Patients
Ji Hyun Jeon, Yong-Soon Yoon, Kwang Jae Lee, Ki Pi Yu, Jong Hoo Lee, Tae Yong Seog, EunJi Son
Ann Rehabil Med 2017;41(3):441-449.   Published online June 29, 2017
DOI: https://doi.org/10.5535/arm.2017.41.3.441
Objective

To develop and test the validity and reliability of a new instrument for measuring the thigh-foot angle (TFA) for the patients with in-toeing and out-toeing gait.

Methods

The new instrument (Thigh-Foot Supporter [TFS]) was developed by measuring the TFA during regular examination of the tibial torsional status. The study included 40 children who presented with in-toeing and out-toeing gaits. We took a picture of each case to measure photographic-TFA (P-TFA) in the proper position and to establish a criterion. Study participants were examined by three independent physicians (A, B, and C) who had one, three and ten years of experience in the field, respectively. Each examiner conducted a separate classical physical examination (CPE) of every participant using a gait goniometer followed by a TFA assessment of each pediatric patient with or without the TFS. Thirty minutes later, repeated in the same way was measured.

Results

Less experienced examiner A showed significant differences between the TFA values depending on whether TFS used (left p=0.003 and right p=0.008). However, experienced examiners B and C did not show significant differences. Using TFS, less experienced examiner A showed a high validity and all examiner's inter-test and the inter-personal reliabilities increased.

Conclusion

TFS may increase validity and reliability in measuring tibial torsion in patients who has a rotational problem in lower extremities. It would be more useful in less experienced examiners.

Citations

Citations to this article as recorded by  
  • Reliability of Tibial and Tibiofibular Torsion Indices Using Ultrasound and Mechanical Devices With an Inertial Measurement Unit (IMU) in Children
    Xavier Ruiz-Tarrazo, Andrea Coda, Carla Sánchez-Dueñas, Salomé Tárrega, Carles Escalona-Marfil
    Ultrasound in Medicine & Biology.2026; 52(7): 1382.     CrossRef
  • Distale tibiale Torsionsosteotomie – Algorithmus von konservativ bis operativ
    Timo Tondelli, Tilman Garthe, Jan-Arie Overberg, Florian B. Imhoff
    Arthroskopie.2025; 38(5): 408.     CrossRef
  • Rotational anomalies in patients with hallux valgus .Observational Study
    Rosana Giménez López
    Revista Española de Podología.2023;[Epub]     CrossRef
  • Comparison of multiple flatfoot indicators in 5–8-year-old children
    Saidas Žukauskas, Vidmantas Barauskas, Emilis Čekanauskas
    Open Medicine.2021; 16(1): 246.     CrossRef
  • Assessment of lower limbs in people with Generalized Joint Hypermobility – preliminary report
    Paulina Ewertowska, Agnieszka Kleniewska, Jakub Wasilewski, Agata Wasilewska, Afrodyta Zielińska, Ireneusz Haponiuk, Dariusz Czaprowski
    Advances in Rehabilitation.2021; 35(4): 25.     CrossRef
  • 8,584 View
  • 117 Download
  • 3 Web of Science
  • 5 Crossref
Effectiveness of Ear Splint Therapy for Ear Deformities
Ji Eun Woo, Yul-Hyun Park, Eun Ji Park, Kyu Yong Park, Sun Hee Kim, Shin-Young Yim
Ann Rehabil Med 2017;41(1):138-147.   Published online February 28, 2017
DOI: https://doi.org/10.5535/arm.2017.41.1.138
Objective

To present our experience with ear splint therapy for babies with ear deformities, and thereby demonstrate that this therapy is an effective and safe intervention without significant complications.

Methods

This was a retrospective study of 54 babies (35 boys and 19 girls; 80 ears; age ≤3 months) with ear deformities who had received ear splint therapy at the Center for Torticollis, Department of Physical Medicine and Rehabilitation, Ajou University Hospital between December 2014 and February 2016. Before the initiation of ear splint therapy, ear deformities were classified with reference to the standard terminology. We compared the severity of ear deformity before and after ear splint therapy by using the physician's ratings. We also compared the physician's ratings and the caregiver's ratings on completion of ear splint therapy.

Results

Among these 54 babies, 41 children (58 ears, 72.5%) completed the ear splint therapy. The mean age at initiation of therapy was 52.91±18.26 days and the treatment duration was 44.27±32.06 days. Satyr ear, forward-facing ear lobe, Darwinian notch, overfolded ear, and cupped ear were the five most common ear deformities. At the completion of therapy, the final physician's ratings of ear deformities were significantly improved compared to the initial ratings (8.28±1.44 vs. 2.51±0.92; p<0.001). There was no significant difference between the physician's ratings and the caregiver's ratings at the completion of ear splint therapy (8.28±1.44 vs. 8.0±1.61; p=0.297).

Conclusion

We demonstrated that ear splint therapy significantly improved ear deformities in babies, as measured by quantitative rating scales. Ear splint therapy is an effective and safe intervention for babies with ear deformities.

Citations

Citations to this article as recorded by  
  • Current Evidence of the Effect of Breastfeeding on Ear Molding Outcomes: A Scoping Review
    Harry Chiang, Samuel R. Shing, Peggy Su‐Genyk, Lilun Li, Kelvin Kwong, Joseph B. Vella
    The Laryngoscope.2026;[Epub]     CrossRef
  • Ear splinting for ear anomalies in infants. Is it worth doing and have we missed the boat? A prospective, cohort study
    Kiron Koshy, Krishna Sagar Eswaravaka Sudha Radha, George Koshy, Rachel Scurrah, David C.G. Sainsbury, Shubhralina Sriram
    Journal of Plastic, Reconstructive & Aesthetic Surgery.2025; 103: 157.     CrossRef
  • Novel thermoplastic splint for treating congenital auricular deformities with late initiation of treatment
    Takuya Suzuki, Shinji Kumegawa, Maiko Inada, Yasuhiro Sakata, Yoshitaka Wada, Gen Yamada, Shinichi Asamura
    JPRAS Open.2025; 46: 703.     CrossRef
  • Correction of congenital auricle deformities with ear mould: A systematic review and meta-analysis
    Jincheng Huang, Kun Zou, Ping Yuan, Min Yang, Yunqi Miao, Li Zhao, Yanjun Fan
    International Journal of Pediatric Otorhinolaryngology.2024; 179: 111903.     CrossRef
  • Ear Molding in Children—Timing, Technique, and Follow-up: A Systematic Review
    Anita Sulibhavi, Sai P. Reddy, Sydney C. Butts, Cecelia E. Schmalbach
    Facial Plastic Surgery & Aesthetic Medicine.2024; 26(6): 730.     CrossRef
  • Prospective Study of Nonsurgical Auricular Correction According to Timing of Treatment
    Myeonggu Seo, Jungwoo Lee, Hyun-Min Lee, Sung-Won Choi, Soo-Keun Kong, Il-Woo Lee, Se-Joon Oh
    Plastic & Reconstructive Surgery.2024; 154(5): 963e.     CrossRef
  • Nonsurgical Creation of an Auriculocephalic Sulcus in Children With Congenital Auricular Deformities
    Hitomi Matsutani, Susam Park, Yohei Ishikawa, Hideaki Kamochi
    Journal of Craniofacial Surgery.2023; 34(3): 964.     CrossRef
  • Spontaneous Resolution of Ear Lidding in Newborns: A Prospective Observational Cohort Study
    Julie Pauwels, D.Y.D. Lu, Frederick K. Kozak, Neil K. Chadha
    Journal of Craniofacial Surgery.2022; 33(2): e141.     CrossRef
  • Noninvasive ear molding in the correction of ear anomalies: A systematic review and meta-analysis
    Elias S. Saba, Stanley Mui, Luke J. Schloegel
    International Journal of Pediatric Otorhinolaryngology.2022; 159: 111189.     CrossRef
  • Assessing outcomes of ear molding therapy by health care providers and convolutional neural network
    Rami R. Hallac, Sarah A. Jackson, Jessica Grant, Kaylyn Fisher, Sarah Scheiwe, Elizabeth Wetz, Jeyna Perez, Jeon Lee, Krishna Chitta, James R. Seaward, Alex A. Kane
    Scientific Reports.2021;[Epub]     CrossRef
  • Can the Elastic of Surgical Face Masks Stimulate Ear Protrusion in Children?
    Bruno Zanotti, Pier Camillo Parodi, Michele Riccio, Francesco De Francesco, Nicola Zingaretti
    Aesthetic Plastic Surgery.2020; 44(5): 1947.     CrossRef
  • Non-surgical Correction of Congenital Ear Anomalies: A Review of the Literature
    Michelle M.W. Feijen, Cas van Cruchten, Phileemon E. Payne, Rene R. W. J. van der Hulst
    Plastic and Reconstructive Surgery - Global Open.2020; 8(11): e3250.     CrossRef
  • 12,319 View
  • 110 Download
  • 12 Web of Science
  • 12 Crossref
Survey of Botulinum Toxin Injections in Anticoagulated Patients: Korean Physiatrists' Preference in Controlling Anticoagulation Profile Prior to Intramuscular Injection
Yongjun Jang, Geun-Young Park, Jihye Park, Asayeon Choi, Soo Yeon Kim, Chris Boulias, Chetan P. Phadke, Farooq Ismail, Sun Im
Ann Rehabil Med 2016;40(2):279-287.   Published online April 25, 2016
DOI: https://doi.org/10.5535/arm.2016.40.2.279
Correction in: Ann Rehabil Med 2016;40(3):556
Objective

To evaluate Korean physiatrists' practice of performing intramuscular botulinum toxin injection in anticoagulated patients and to assess their preference in controlling the bleeding risk before injection.

Methods

As part of an international collaboration survey study, a questionnaire survey was administered to 100 Korean physiatrists. Physiatrists were asked about their level of experience with botulinum toxin injection, the safe international normalized ratio range in anticoagulated patients undergoing injection, their tendency for injecting into deep muscles, and their experience of bleeding complications.

Results

International normalized ratio <2.0 was perceived as an ideal range for performing Botulinum toxin injection by 41% of the respondents. Thirty-six respondents replied that the international normalized ratio should be lowered to sub-therapeutic levels before injection, and 18% of the respondents reported that anticoagulants should be intentionally withheld and discontinued prior to injection. In addition, 20%–30% of the respondents answered that they were uncertain whether they should perform the injection regardless of the international normalized ratio values. About 69% of the respondents replied that they did have any standardized protocols for performing botulinum toxin injection in patients using anticoagulants. Only 1 physiatrist replied that he had encountered a case of compartment syndrome.

Conclusion

In accordance with the lack of consensus in performing intramuscular botulinum toxin injection in anticoagulated patients, our survey shows a wide range of practices among many Korean physiatrists; they tend to avoid botulinum toxin injection in anticoagulated patients and are uncertain about how to approach these patients. The results of this study emphasize the need for formulating a proper international consensus on botulinum toxin injection management in anticoagulated patients.

Citations

Citations to this article as recorded by  
  • Dry Needling and Antithrombotic Drugs
    María Muñoz, Jan Dommerholt, Sara Pérez-Palomares, Pablo Herrero, Sandra Calvo, Massimiliano Valeriani
    Pain Research and Management.2022; 2022: 1.     CrossRef
  • Antihemorrhagic Properties of Therapeutic Botulinum Toxin in Experimental Mice
    Sowbarnika Ravichandran, Jerly Helan Mary Joseph, Shanmugaapriya Sellathamby, Mahesh Kandasamy
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Botulinum Toxin Injection and Electromyography in Patients Receiving Anticoagulants: A Systematic Review
    Yeow Leng Tan, Tze Chao Wee
    PM&R.2021; 13(8): 880.     CrossRef
  • Intravesical onabotulinumtoxinA injections in patients on antiplatelet and anticoagulation therapy
    Elsie E. Mensah, Bogdan Toia, Linh Nguyen, Rizwan Hamid, Mahreen Pakzad, Jeremy L. Ockrim, Roger Walker, Tamsin J. Greenwell, Tharani Nitkunan, Davendra Sharma, Jai H. Seth
    Neurourology and Urodynamics.2021; 40(7): 1829.     CrossRef
  • Management of antithrombotics for intramuscular injection of botulinum toxin for spasticity. A survey of real-life practice in France
    Ozoua Ble, Djamel Bensmail, Dominic Pérennou, Bernard Parratte, Pierre-Alain Joseph, François-Constant Boyer, Hugues Michelon, Thibaud Lansaman, Jonathan Levy
    Annals of Physical and Rehabilitation Medicine.2021; 64(6): 101467.     CrossRef
  • Challenges in the management of anticoagulated patients with focal spasticity
    Chris Boulias, Farooq Ismail, Chetan P. Phadke
    Toxicon.2020; 177: 93.     CrossRef
  • Safety of OnabotulinumtoxinA with Concomitant Antithrombotic Therapy in Patients with Muscle Spasticity: A Retrospective Pooled Analysis of Randomized Double-Blind Studies
    Rozalina Dimitrova, Lynn James, Chengcheng Liu, Amelia Orejudos, Irina Yushmanova, Mitchell F. Brin
    CNS Drugs.2020; 34(4): 433.     CrossRef
  • Botulinum toxin therapy in patients with oral anticoagulation: is it safe?
    Christoph Schrader, Markus Ebke, Fereshte Adib Saberi, Dirk Dressler
    Journal of Neural Transmission.2018; 125(2): 173.     CrossRef
  • A Delphi-Based Consensus Statement on the Management of Anticoagulated Patients With Botulinum Toxin for Limb Spasticity
    Chris Boulias, Farooq Ismail, Chetan P. Phadke, Stephen Bagg, Isabelle Bureau, Stephane Charest, Robert Chen, Albert Cheng, Karen Ethans, Milo Fink, Heather Finlayson, Sivakumar Gulasingam, Meiqi Guo, Muriel Haziza, Hossein Hosseini, Omar Khan, Michael La
    Archives of Physical Medicine and Rehabilitation.2018; 99(11): 2183.     CrossRef
  • Prevalence of Bleeding Complications Following Ultrasound‐Guided Botulinum Toxin Injections in Patients on Anticoagulation or Antiplatelet Therapy
    Jeffrey LaVallee, Regan Royer, Geoffrey Smith
    PM&R.2017; 9(12): 1217.     CrossRef
  • Patterns of botulinum toxin treatment for spasticity and bleeding complications in patients with thrombotic risk
    Chetan P. Phadke, Vivekanand Thanikachalam, Farooq Ismail, Chris Boulias
    Toxicon.2017; 138: 188.     CrossRef
  • 11,477 View
  • 65 Download
  • 11 Web of Science
  • 11 Crossref
Craniofacial Asymmetry in Adults With Neglected Congenital Muscular Torticollis
Kil-Yong Jeong, Kyung-Jay Min, Jieun Woo, Shin-Young Yim
Ann Rehabil Med 2015;39(3):440-450.   Published online June 30, 2015
DOI: https://doi.org/10.5535/arm.2015.39.3.440
Objective

To evaluate the craniofacial asymmetry in adults with neglected congenital muscular torticollis (CMT) by quantitative assessment based on craniofacial three-dimensional computed tomography (3D-CT).

Methods

Preoperative craniofacial asymmetry was measured by 3D-CT for 31 CMT subjects ≥18 years of age who visited a tertiary medical center and underwent 3D-CT between January 2009 and December 2013. The relationship between the age and the severity of craniofacial asymmetry was analyzed in reference to anteroposterior length asymmetry of the frontal bone and zygomatic arch, vertical and lateral displacements of the facial landmarks, and mandibular axis rotation.

Results

The age at CT was 27.71±7.02 years (range, 18-44 years). All intra-class correlation coefficients were higher than 0.7, suggesting good inter-rater reliability (p<0.05) of all the measurements. The frontal and the zygomatic length ratio (i.e., the anteroposterior length asymmetry on the axial plane) was 1.06±0.03 and 1.07±0.03, respectively, which was increased significantly with age in the linear regression analysis (r2=0.176, p=0.019 and r2=0.188, p=0.015, respectively). The vertical or lateral displacement of the facial landmarks and rotation of the mandibular axis did not significantly correlate with age (p>0.05).

Conclusion

Craniofacial asymmetry of neglected CMT became more severe with age in terms of anteroposterior length asymmetry of the ipsilateral frontal bone and zygomatic arch on the axial plane even after growth cessation. This finding may enhance the understanding of therapeutic strategies for craniofacial asymmetry in adults with neglected CMT.

Citations

Citations to this article as recorded by  
  • Evaluating fluctuating and directional asymmetry in postnatal petrous bone growth: a 3D morphometric study
    Magali Bourgoin, Paul Landais, Gérard Subsol, Guillaume Captier
    Surgical and Radiologic Anatomy.2026;[Epub]     CrossRef
  • Craniofacial Asymmetric Patterns in Congenital Muscular Torticollis: A Computed Tomography-Based Visual Classification and Cluster Analysis With Clinical Implications
    Magali Bourgoin, Paul Landais, Gérard Subsol, Mael-Morvan Duroyon, MarieChristine Picot, Guillaume Captier
    Journal of Craniofacial Surgery.2026;[Epub]     CrossRef
  • Clinical Efficacy of Arthroscopic Minimally Invasive Treatment in Children With Congenital Muscular Torticollis: A Retrospective Study
    Xiao-Wei Wang, Zi-Ming Yao, Di-Ming Zhou, Yi-Jun Yang, Dong Guo, Lei Zhang
    Journal of Pediatric Surgery.2025; 60(5): 162268.     CrossRef
  • Non-Surgical Correction of Facial Asymmetry: A Narrative Review of Non-Surgical Modalities and Clinical Case Examples
    Clara Lee, Sumin Chae, Han-Jin Kwon, Wonwoo Jeong, Kyung Kwan Lee, Minsuk Chae
    Journal of Clinical Medicine.2025; 14(24): 8828.     CrossRef
  • A Quantitative Analysis of Facial Asymmetry in Torticollis Using 3-Dimensional Photogrammetry
    Vanessa M. Baratta, Olivia E. Linden, Margaret E. Byrne, Stephen R. Sullivan, Helena O. Taylor
    The Cleft Palate Craniofacial Journal.2022; 59(1): 40.     CrossRef
  • The Impact of Surgical Correction in Changing Morphometric Dimensions of Craniofacial Deformities and Facial Asymmetry in Congenital Muscular Torticollis: An Otolaryngologists Perspective
    Tripti Maithani, Arvind Mamgain, Apporva Kumar Pandey, Sharad Hernot, Kanika Arora
    Indian Journal of Otolaryngology and Head & Neck Surgery.2022; 74(S3): 5569.     CrossRef
  • Occlusal deviations in adolescents with idiopathic and congenital scoliosis
    Hao Zhang, Jingbo Ma, Zhicheng Zhang, Yafei Feng, Chuan Cai, Chao Wang
    Korean Journal of Orthodontics.2022; 52(3): 165.     CrossRef
  • The usefulness, reliability, and quality of YouTube video clips on congenital muscular torticollis: A STROBE compliant study
    Kil-Yong Jeong, Hyun Jung Lee, Shin-Young Yim
    Medicine.2022; 101(37): e30502.     CrossRef
  • Ipsilateral Hypertrophy of the Mastoid Process in Surgical Cases of Congenital Muscular Torticollis
    Hyun Gi Kim, Shin-Young Yim
    The Cleft Palate Craniofacial Journal.2019; 56(10): 1295.     CrossRef
  • Cervical Spine Dysmorphism in Congenital Muscular Torticollis
    Mohammed Ahmed Hussein, In Sik Yun, Dong won Lee, Hanna Park, Kim Yong Oock
    Journal of Craniofacial Surgery.2018; 29(4): 925.     CrossRef
  • Description of Mandibular Improvements in a Series of Infants With Congenital Muscular Torticollis and Deformational Plagiocephaly Treated With Physical Therapy
    Regina Fenton, Susan Gaetani, Zoe MacIsaac, Eric Ludwick, Lorelei Grunwaldt
    The Cleft Palate-Craniofacial Journal.2018; 55(9): 1282.     CrossRef
  • Cervical Spine Deformity in Long-Standing, Untreated Congenital Muscular Torticollis
    Mohammed Ahmed Hussein, In Sik Yun, Hanna Park, Yong Oock Kim
    Journal of Craniofacial Surgery.2017; 28(1): 46.     CrossRef
  • The Versatility of Cervical Vertebral Segmentation in Detection of Positional Changes in Patient with Long Standing Congenital Torticollis
    Mohammed Ahmed Hussein, Yong Oock Kim
    Journal of International Society for Simulation Surgery.2016; 3(1): 28.     CrossRef
  • Effectiveness of Surgical Release in Patients With Neglected Congenital Muscular Torticollis According to Age at the Time of Surgery
    Kyung-Jay Min, Ah-Reum Ahn, Eun-Ji Park, Shin-Young Yim
    Annals of Rehabilitation Medicine.2016; 40(1): 34.     CrossRef
  • 11,488 View
  • 108 Download
  • 12 Web of Science
  • 14 Crossref
A New Ultrasound Method for Assessment of Head Shape Change in Infants With Plagiocephaly
Jin Kyung Kim, Dong Rak Kwon, Gi-Young Park
Ann Rehabil Med 2014;38(4):541-547.   Published online August 28, 2014
DOI: https://doi.org/10.5535/arm.2014.38.4.541
Objective

To compare a new ultrasound measurement method with calliper cephalometry in infants with deformational plagiocephaly (DP) and to assess the differences of two methods according to the severity of DP.

Methods

Fifty-two infants with DP were divided into two groups according to the degree of cranial vault asymmetry (CVA); group 1 included 42 infants with CVA over 10 mm, and group 2 included 10 infants with CVA under 10 mm. Cranial vault asymmetry index (CVAI) and occipital angle ratio (OAR) were measured by using calliper and ultrasound measurements, respectively. The occipital angle was defined as the angle between the lines projected along the lambdoid sutures of the skull.

Results

The occipital angles of the affected sides were significantly greater than those of unaffected sides in both groups. The CVAI and OAR were significantly greater in group 1 than in group 2 (CVAI, 9.3%±2.3% vs. 4.6%±1.5%; OAR, 1.05±0.4 vs. 1.01±0.0; p<0.05). The OAR was positively correlated with the CVAI in all infants (r=0.789) and in group 1 (r=0.784; p<0.05).

Conclusion

Our study revealed that OAR using the new ultrasound measurement was positively correlated with the CVAI in infants with DP. Therefore, the occipital angle measurement using ultrasound combined with cephalometry could provide better understanding about the characteristics of the overall cranial bone and lambdoid suture complex in infants with DP.

Citations

Citations to this article as recorded by  
  • 3D-Printed Helmet Therapy in Infants with Positional Cranial Deformity: Effectiveness and Parents’ Satisfaction
    Hannelore Willenborg, Pauline Seniow, Dorothea Daentzer
    JPO Journal of Prosthetics and Orthotics.2026; 38(2): 94.     CrossRef
  • Predictive Value of Sonographic Parameters on the Effects of Cranial Molding Helmet Therapy in Infants with Positional Plagiocephaly
    Maria Licci, Agnes Paasche, Alexandru Szathmari, Pierre-Aurélien Beuriat, Carmine Mottolese, Raphael Guzman, Federico Di Rocco
    Diagnostics.2024; 14(13): 1407.     CrossRef
  • Ultrasonographic Measurement of Anterior Fontanelle Size in Infants with Deformational Plagiocephaly
    Jae Hee Lee, Gi-Young Park, Dong Rak Kwon
    Journal of Clinical Medicine.2024; 13(17): 5012.     CrossRef
  • Ultrasonography as first line imaging for the diagnosis of positional plagiocephaly
    Fiammetta SERTORIO, Mattia PACETTI, Simone SCHIAFFINO, Francesca SECCI, Armando CAMA, Alessandro CONSALES, Gian M. MAGNANO
    Minerva Pediatrics.2023;[Epub]     CrossRef
  • Neurodevelopmental delay according to severity of deformational plagiocephaly in children
    Dong Han Kim, Dong Rak Kwon
    Medicine.2020; 99(28): e21194.     CrossRef
  • Deformational plagiocephaly: State of the art and review of the literature
    P.-A. Beuriat, A. Szathmari, F. Di Rocco, C. Mottolese
    Neurochirurgie.2019; 65(5): 322.     CrossRef
  • Sonographic Analysis of Changes in Skull Shape After Cranial Molding Helmet Therapy in Infants With Deformational Plagiocephaly
    Dong Rak Kwon
    Journal of Ultrasound in Medicine.2016; 35(4): 695.     CrossRef
  • A Craniometer with a Headband Can Be a Reliable Tool to Measure Plagiocephaly and Brachycephaly in Clinical Practice
    Anna Öhman
    Health.2016; 08(12): 1258.     CrossRef
  • 7,079 View
  • 64 Download
  • 8 Web of Science
  • 8 Crossref

Case Reports

A Nine-Month-Old Boy With Isodicentric Chromosome 15: A Case Report
Doug Ho Park, Seonggyu Lim, Eun Sook Park, Eun Geol Sim
Ann Rehabil Med 2013;37(2):291-294.   Published online April 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.2.291

Isodicentric chromosome 15 [idic(15)] is a rare chromosomal abnormality that occurs due to inverted duplication of chromosome 15q. It is associated with many clinical findings such as early central hypotonia, developmental delay, cognitive dysfunction, autism spectrum disorders, and seizure. Delayed development is a common problem referred to pediatric rehabilitation clinics. A 9-month-old boy with delayed development was referred to our clinic for assessment and treatment. On chromosomal analysis, he was diagnosed as idic(15) syndrome with 47,XY,+idic(15)(q12) on karyotyping. Herein we describe his clinical manifestations and provide a brief review of the related literature.

Citations

Citations to this article as recorded by  
  • Neurodevelopmental disorders and microcephaly: how apoptosis, the cell cycle, tau and amyloid-β precursor protein APPly
    Deborah K. Sokol, Debomoy K. Lahiri
    Frontiers in Molecular Neuroscience.2023;[Epub]     CrossRef
  • Acute lymphoblastic leukemia in a nine-year-old girl with isodicentric chromosome 15 syndrome
    Roberto Antonucci, Nadia Vacca, Elisa Ghisu, Gloria Acquaviva, Carlo Cosmi, Anna Maria Marinaro, Cristian Locci, Claudio Fozza
    Cancer Genetics.2019; 235-236: 93.     CrossRef
  • Rare partial octosomy and hexasomy of 15q11-q13 associated with intellectual impairment and development delay: report of two cases and review of literature
    Haiyu Li, Juan Du, Wen Li, Dehua Cheng, Wenbin He, Duo Yi, Bo Xiong, Shimin Yuan, Chaofeng Tu, Lanlan Meng, Aixiang Luo, Ge Lin, Guangxiu Lu, Yue-Qiu Tan
    Molecular Cytogenetics.2018;[Epub]     CrossRef
  • Organization of the human superior olivary complex in 15q duplication syndromes and autism spectrum disorders
    R. Lukose, K. Beebe, R.J. Kulesza
    Neuroscience.2015; 286: 216.     CrossRef
  • Isodicentric Chromosome 15 Syndrome in a Korean Patient With Café-au-lait Spots
    John Hoon Rim, Hee Jung Chung, Saeam Shin, Seo-Jin Park, Jong Rak Choi
    Annals of Laboratory Medicine.2015; 35(4): 474.     CrossRef
  • Clinical, Cytogenetic, and Biochemical Analyses of a Family with a t(3;13)(q26.2;p11.2): Further Delineation of 3q Duplication Syndrome
    M. Abreu-González, C. García-Delgado, A. Cervantes, A. Aparicio-Onofre, R. Guevara-Yáñez, R. Sánchez-Urbina, M. P. Gallegos-Arreola, A. Luna-Angulo, F. J. Estrada, V. F. Morán-Barroso
    Case Reports in Genetics.2013; 2013: 1.     CrossRef
  • 9,637 View
  • 41 Download
  • 6 Crossref
Anomalous Course of the Extensor Pollicis Longus With Multiple Absences of Thumb Muscles
Jayoung Hong, Don-Kyu Kim, Si Hyun Kang, Kyung-Mook Seo
Ann Rehabil Med 2013;37(1):151-155.   Published online February 28, 2013
DOI: https://doi.org/10.5535/arm.2013.37.1.151

We report a rare case of a 10-year-old girl with anomalous course of extensor pollicis longus (EPL) muscle, which exists with absence of thenar muscles and muscles in the 1st extensor compartment. Her chief complaint was severe atrophy on the right thenar eminence. On physical examination, there was no obvious functional abnormality on her right thumb. On magnetic resonance imaging, we found that the abductor pollicis brevis, opponens pollicis, abductor pollicis longus, and extensor pollicis brevis muscles were absent. The tendon of the EPL muscle was found, but it had abnormal insertion on the radial side of the proximal phalanx, not on the distal phalanx. This variation was thought to have played a major role in compensating for impaired abduction of the thumb, which is usually accompanied by agenesis of major abductors of the thumb.

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Original Articles

The Availability of Radiological Measurement of Tibial Torsion: Three-Dimensional Computed Tomography Reconstruction
Sang-yeop Shin, Chul Ho Yoon, Eun Shin Lee, Min-Kyun Oh, A Ram Kim, Jong Moon Park, Jun-Hwa Shin, Hee Suk Shin
Ann Rehabil Med 2011;35(5):673-679.   Published online October 31, 2011
DOI: https://doi.org/10.5535/arm.2011.35.5.673
Objective

To assess the intra-rater and inter-rater reliability for measuring tibial torsion measurements by a radiographic method using three-dimensional computed tomography reconstruction (3D-CT) and to compare the physical measures to those of 3D-CT.

Method

The study included 33 children who presented with intoeing gait. Tibial torsion was measured by 3D-CT. Distal reference point was the bimalleolar axis. Proximal reference points were the transtibial axis and posterior condylar axis. Physical measurements included thigh-foot angle (TFA) and bimalleolar angle (BMA). 3D-CT measurement and physical measurement were performed twice at both lower extremities by each rater. The intra-rater and inter-rater reliability were calculated by intraclass correlation coefficiency (ICC). The relationship between radiological and physical examination was calculated by Spearman correlation coefficient.

Results

The 3D-CT measures for tibial torsion were reliable within individual raters and between different raters. However, physical measures for tibial torsion were reliable within an individual rater but not reliable between raters. The 3D-CT measures by any proximal reference axis were more reliable within a rater and between raters than physical measurements. There was no significant impact introduced by the selection of the proximal reference axis. The correlation coefficiency between 3D-CT and physical measurement methods was low.

Conclusion

Because the 3D-CT measurements for tibial torsion are more reliable than physical measurements, we recommend that accurate diagnosis of internal tibial torsion should be detected by using 3D-CT measurements. Also, considering the disadvantages of radiological measurements, physical measurement may be used for short term follow-up by same raters, as intra-rater reliability is relatively good.

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    Stephan Waelti, Tim Fischer, Jennifer Griessinger, Johannes Cip, Tobias Johannes Dietrich, Michael Ditchfield, Thomas Allmendinger, Michael Messerli, Stefan Markart
    Insights into Imaging.2022;[Epub]     CrossRef
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    Federico Longo, Tommaso Nicetto, Antonio Pozzi, Barbara Contiero, Maurizio Isola
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  • Internal tibial torsion is related to syndesmosis injury in a large osteological collection
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  • Standardization of torsional CT measurements of the lower limbs with threshold values for corrective osteotomy
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    Archives of Orthopaedic and Trauma Surgery.2019; 139(6): 795.     CrossRef
  • Radiographic markers for measuring tibial rotation based on CT-reconstructed radiographs: an accuracy and feasibility study
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    Skeletal Radiology.2018; 47(4): 483.     CrossRef
  • Femoral Version and Tibial Torsion are Not Associated With Hip or Knee Arthritis in a Large Osteological Collection
    Douglas S. Weinberg, Paul J. Park, William Z. Morris, Raymond W. Liu
    Journal of Pediatric Orthopaedics.2017; 37(2): e120.     CrossRef
  • Femoral and tibial torsion measurements in children and adolescents: comparison of MRI and 3D models based on low-dose biplanar radiographs
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  • Tibial rotational osteotomy and distal tuberosity transfer for patella subluxation secondary to excessive external tibial torsion: surgical technique and clinical outcome
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  • Does Lower Limb Torsion Matter?
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The Value of Electrodiagnostic Studies Performed before and after Microvascular Decompression.
Kim, Myeong Ok , Jung, Han Young , Kim, Chang Hwan , Kim, Eun Young , Lee, Hye Jin , Yeo, Sang Won
J Korean Acad Rehabil Med 2009;33(6):687-692.
Objective
To evaluate the usefulness of electrodiagnostic studies in hemifacial spasm patients by comparing abnormal muscle response (AMR) and irregular bursting discharge (IBD) before and after the surgery of hemifacial spasm. Method: Fifty nine patients who had been diagnosed with hemifacial spasm and underwent microvascular decompression (MVD) were chosen. The AMR was carried out in three different ways; 1) abnormal response of orbicularis oris when stimulating the supraorbital branch of trigeminal nerve (AMR1), 2) abnormal response of mentalis when stimulating the zygomatic branch of facial nerve (AMR2) and 3) abnormal response of orbicularis oculi when stimulating the marginal mandibular branch of facial nerve (AMR3). We identified the correlation between the loss of IBD and the AMR results per each method, the results of the electrodiagnostic studies according to the onset duration, and the point of follow up time. Results: The AMR and IBD decreased or disappeared after the surgery. AMR which had a significant statistical correlation with the changes of IBD, were AMR2 and AMR3. No definite changes were seen regarding the onset duration. According to the studies done during the follow up period, there was a significant reduction in lateral spread and IBD as the length of the follow up period lengthened. Conclusion: Investigation of pre- and postoperative electrodiagnostic study, especially abnormal muscle response (facio- facial reflex) is very helpful in predicting the outcome of operation and the overall prognosis. (J Korean Acad Rehab Med 2009; 33: 687-692)
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Objective
To find the correlation between dorsal root ganglion location and abnormal superficial peroneal sensory nerve action potential (SNAP) response in L5 radiculopathy. Method: This retrospective study included thirty-three patients with unilateral L5 radiculopathy, who had no peripheral polyneuropathy, focal neuropathy or other metabolic disease and were under 60 years. 33 patients were classified to two groups: group I with an abnormal superficial peroneal SNAP response and group II with a normal superficial peroneal SNAP response. Using axial view of MRI, the location of dorsal root ganglion (DRG) of the study group was classified into intraspinal, intraforaminal and extraforaminal space. Results: In group I, 71% of L4 dorsal root ganglion was located in intraforaminal space, and 14% in extraforaminal space and 64% of L5 DRG was in intraforaminal space and 14% in intraspinal. In Group II, 42% of L4 DRG was located in intraforaminal space, and 58% in extraforaminal and 26% of L5 DRG in intraforaminal space and 63% in extraforaminal space. Group I subjects were more located in the intraforaminal space than Group II subjects (p<0.05). Conclusion: In spite of belief that "radiculopathy involves the nerve root proximal to DRG", the significant proportion of dorsal root ganglion was located inside intraforaminal space. Thus the intraspinal lesion such as disc protrusion or spondylotic encroachment may compress DRG and cause abnormal findings of SNAP in EMG study. (J Korean Acad Rehab Med 2009; 33: 309-315)
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Analysis of Interference Pattern of Quantitative Electromyography in Early Adolescence.
Park, Ki Deok , Lee, Sang Chul , Park, Yoon Ghil , Moon, Jae Ho
J Korean Acad Rehabil Med 2007;31(3):333-340.
Objective
To establish turns-amplitude, activity-envelope amplitude and activity-number of small segements (NSS) clouds of normal early teens using interference pattern. Method: Forty four healthy early adolescence from 11 to 15 years old participated in this study. The interference patterns were analyzed using quantitative electromyography of the biceps brachi and tibialis anterior muscles. The interference patterns were measured at 3 to 5 different force levels ranging from minimum to maximum and turns, mean amplitude, activity, envelope amplitude, NSS were analyzed. By turns/amplitude, activity/envelope amplitude and activity/ NSS ratio, normal clouds of gender related each parameters were obtained. Results: The turns-amplitude, activity-envelope amplitude and activity-NSS ratio of the biceps brachii and tibialis anterior muscles were obtained. Normal clouds of gender related turns-amplitude, activity-envelope amplitude and activity-NSS for each muslces were established. Conclusion: By using normal cloud patterns of turns- amplitude, activity-envelope amplitude and activity-NSS, automatic interference pattern analysis may contribute to diagnose neuromuscular disease in early adolescent patients. (J Korean Acad Rehab Med 2007; 31: 333-340)
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Case Report

Segmental Spinal Dysgenesis: Case report.
Park, Song Rae , Park, Jin Hong , Sung, In Young
J Korean Acad Rehabil Med 2007;31(1):127-130.
Segmental spinal dysgenesis (SSD) is a rare congenital abnormality in which a segment of the spine and spinal cord fails to develop properly. Segmental vertebral anomalies involve the thoracolumbar, lumbar, or lumbosacral spine. We report two cases of SSD associated with other spinal dysraphism. Radiologic investigations revealed segmental dysgenesis of thoracic spinal cord without an associated vertebral bony anomaly in one case and segmental dysgenesis of the cervico-thoracic cord with diastematomyelia in the other case. The neurologic picture depends on the severity of the malformation and on its segmental level along the longitudinal embryonic axis. The pathogenesis of SSD syndrome is not clear but its cause is probably related to a segmental maldevelopment of the neural tube. (J Korean Acad Rehab Med 2007; 31: 127-130)
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Original Articles

The Development of Abnormal Spontaneous Activities in the Experimental Radiculopathy in the Rat.
Han, Tai Ryoon , Lee, Seong Jae , Kwon, Bum Sun , Hyun, Jung Keun , Park, Won Beom
J Korean Acad Rehabil Med 2005;29(4):392-397.
Objective
Through a animal study using rats, we investigated whether abnormal spontaneous activities (ASAs) could be observed in the radiculopathies of biochemical and mechanical model. Method: A total of 30 Sprague-Dawley male rats were randomly assigned into sham, nucleus pulposus (NP) and ligation groups. In the sham group, the right L4 and L5 nerve roots were exposed by laminectomies. In the NP group, nucleus pulposus was transplanted onto nerve roots from tail. In the ligation group, exposed nerve roots were ligated by silk ligatures. All rats were evaluated by mechanical allodynia, motor paresis, and the needle electromyography (EMG) examination. Results: Mechanical allodynia was observed on the 4th and 7th postoperative days in NP and ligation groups. Motor paresis was observed only in the ligation group. The needle EMG showed ASAs on the 4th postoperative day, but decreased in incidence and amount on the 7th postoperative day in the NP and ligation groups. Conclusion: The ASAs can be observed by the biochemical action of nucleus pulposus as well as the mechanical compression. The results of this study may help explain the discrepancy between radiologic and electrodiagnostic findings. (J Korean Acad Rehab Med 2005; 29: 392-397)
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The Effect of Metatarsal Pad for Foot Pressure.
Lee, Gyu Hoon , Han, Seung Jin , Lee, Sang Gun , Park, Si Bog
J Korean Acad Rehabil Med 2004;28(1):94-97.
Objective
To compare the foot pressure of the insole with medial longitudinal arch support and metatarsal pad and insole with medial longitudinal arch support only. Method: Thirty three normal subjects participated in this study. Insole were fabricated by Hana-meditec company after shaping the subjects' foot. The left insole had only medial longitudinal arch support and right insole had medial longitudinal arch support with metatarsal pad. Bare foot pressure were measured by EMED systemduring comfortable gait. Shoes were manufactured by Osan University. Foot pressure in the shoes was measured by PEDAR system during comfortable gait. Plantar pressure were analyzed by PEDAR C-expert program at T0 (whole foot), M1 (heel), M2 (midfoot), M3 (1st and 2nd metatarsal area), M4 (3rd, 4th and 5th metatarsal area), M5 (great toe), M6 (2nd and 3rd toes area), and M7 (4th and 5th toes area) zone. Results: Right bare foot plantar peak pressure was identical with left side. Right plantar peak pressure with metatarsal pad in shoes was lower than left side with medial longitudinal arch support only at M1, M2 and M4 zone. Conclusion: For reducing the plantar peak pressure, the insole with medial longitudinal arch support and metatarsal pad were better than the insole with medial longitudinal arch support only. (J Korean Acad Rehab Med 2004; 28: 94-97)
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Case Report

We present four pediatric cases examined by diffusion tensor MRI (DTI) to investigate microstructural abnormalities of brain related to their neurologic disability and motor weakness, following absence of any remarkable lesion on the motor pathway in conventional MRI. DTI is a relatively novel MR technique that enables investigation of the orientation and integrity of white matter fiber tracts of the brain in vivo. Case 1, 2 and 3 had suffered from cerebral palsy and case 4 had developed left hemiparesis

after a traumatic brain injury. Conventional brain MRI presented no specific abnormality in case 1 and 2, a focal encephalomalacia in the left anterior thalamus in case 3, and contusional hemorrhages in the left temporal and parietal lobes in case 4. But DTI disclosed microstructural abnormalities on descending motor pathway including the posterior limb of the internal capsule or the cerebral peduncle of the midbrain in all cases. (J Korean Acad Rehab Med 2003; 27: 446-450)

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Original Articles
Evidence of Microstructural Abnormality on Descending Motor Pathway in Cerebral Plasied Children with Periventricular Leukomalacia: Diffusion Tensor MRI Study.
Lee, Zee Ihn , Park, Sung Min , Ahn, Sang Ho , Jang, Sung Ho , Son, Su Min , Byun, Woo Mok
J Korean Acad Rehabil Med 2003;27(3):340-343.
Objective
Using diffusion tensor MRI (DTI), to investigate the microstructural abnormality of corticospinal tract in the cerebral palsied children with periventricular leukomalacia on conventional MRI and to recognize the clinical usefulness of DTI.

Method: Seven patients were studied. DTI was peformed using 1.5T MR scanner (Vision Plus, Siemens, Erlangen, Germany) and fractional anisotropies of corona radiata, posterior limbs of internal capsules, and cerebral peduncles of midbrain in both hemisphere were calculated.

Results: The fractional anisotropy was significantly decreased in all corona radiata, posterior limbs of internal capsules, cerebral peduncles of midbrain in six patients except one hemiplegic patient, compared with that of control group. In in the hemiplegic patient, the fractional anisotropy was reduced only in affected hemisphere. In addition, the fractional anisotropy tended to be also increased as gross motor function measure (GMFM) score was increased.

Conclusion: We believe that DTI may be efficient in evaluating microstructural abnormality on the motor pathway of brain and helpful in providing prognosis of clinical findings in cerebral palsied children with periventricular leukomalacia. (J Korean Acad Rehab Med 2003; 27: 340-343)

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Scoring of Norms of the Gross Motor Function Measure (GMFM) in Normal Children.
Sung, In Young , Cho, Seung Chan , Lee, Nam Hyun
J Korean Acad Rehabil Med 2002;26(4):398-402.

Objective: We performed to obtain the normal values of Gross Motor Function Measure (GMFM) in normally developed children. We designed this study to inform the degree of gross motor functional disability or delay in children with cerebral palsy, comparing with score values of GMFM in normal children.

Method: One hundred-sixteen normally developed children who were in the age of 12 to 47 months were recruited. Their GMFM tests were performed by a pediatric physical therapist. They were grouped by age of 6 months and the scores were compared with all of each groups.

Results: The GMFM scores in normal children increased with ages. The rates of increment in scores were fast till 35 months of age and inter-individual differences of GMFM scores were greater in younger age groups (less than 36 months of age) than older groups. Even the means of GMFM scores were higher in the girls than boys, the differences between sexes were insignificant statistically.

Conclusion: Norms of GMFM obtained in normally developed children who were in the age of 12 to 47 months. It would be helpful to assess the degree of motor functional disabilities or delay in children with physical disabilities. (J Korean Acad Rehab Med 2002; 26: 398-402)

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Quantitative Sensory Test in Normal Adult.
Shin, Jung Bin , Cho, Kyung Ja , Jang, Sung Goo , You, Sung , Seong, Yeon Jae , Park, Jong Ryool
J Korean Acad Rehabil Med 2000;24(3):509-516.

Objective: To obtain normal data of quantitative sensory test (QST) in Korean adult.

Method: The subjects were 85 normal adults aging from 30 to 69 years old, who had no abnormal sensory and neurologic problem. We performed following three QSTs on dominant side and one verbal questionnaire. 1) Semmes-Weinstein monofilament wire system (0.05 G, 0.2 G, 2 G, 4 G, 10 G, 300 G) for touch sensation, 2) Rydel-Seiffer Tuning Fork for vibration sensation, 3) TSA-2001 Thermal sensory analyser for thermal sensation, 4)University of Texas Subjective Peripheral Neuropathy verbal questionnaire.

Results: 1) Touch perception score measured with Semmes-Weinstein monofilament wire system, declined with age (p<0.01). 2) Vibration perception score measured with the tuning fork, declined with age in foot (p<0.01). 3) Warm sense and heat pain threshold measured with TSA-2001 thermal sensory analyser increased with age, and cold sense and cold pain threshold declined with age. 4) Weight showed negative correlation with vibration perception score in man's foot.

Conclusion: Normal data of three sensory test obtained from this study could be used for the early detection of peripheral neuropathy or loss of "protective sensation".

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The Optimal Measurement of Across Elbow Segment in Ulnar Motor Conduction Study.
Paik, Nam Jong , Han, Tai Ryoon , Lee, In Sik
J Korean Acad Rehabil Med 1999;23(5):980-985.

Objective: There is a room for considerable error in the measurement of across-elbow conduction velocity due to the different possible positions of the elbow and the difficulty in measuring distance accurately. We propose a technique for the measurement of conduction velocity through the elbow segment in a fully flexed elbow position with the arm abducted at 90o.

Method: We assumed 'ideal' across-elbow segmental conduction velocity is the mean of the forearm and arm segmental conduction velocities, and established an optimal deflection point at the elbow, which best reflects the ideal conduction velocity in normal healthy subjects. Five deflection points were examined at the elbow. Segmental conduction velocities of across-elbow segments were calculated at each of these points, using the sum of the linear distances from each point to the proximal above-elbow cathode stimulation site and to the distal below-elbow cathode stimulation site.

Results: The optimal deflection point was the midpoint between the epicondyle and the olecranon in an arm abducted 90o and elbow fully flexed position.

Conclusion: Our data suggests that an across-elbow segment velocity lower than 54.2 m/sec, or a difference of more than 11.6 m/sec between the across-elbow and forearm segments is to be considered abnormal. The lower limit values expressed as mean - 2 S.D. for absolute across-elbow segmental conduction velocity and relative velocity difference between the across- elbow segment and forearm segments at other possible deflection points of the elbow were also calculated.

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Change of Abnormal Spontaneous Activities According to Time Course in Hemiplegic Upper Limb.
Cha, Sang Min , Hwang, Chi Moon , Kim, Hee Sang , Ahn, Kyung Hoi
J Korean Acad Rehabil Med 1999;23(3):538-543.

Objective: To evaluate the change of abnormal spontaneous activities according to the clinical and radiologic findings, and to the time course after onset in hemiplegic upper limb.

Method: We scored abnormal spontaneous activities of hemiplegic upper limb muscles (infraspinatus, deltoid, extensor carpi radialis, abductor pollicis brevis, abductor digiti minimi) in 100 hemiplegic patients without peripheral neuropathy. The abnormal spontaneous activities were evaluated according to their radiologic findings and to Brunnstrom stage and the presence of reflex sympathetic dystrophy (RSD), and the time course after the onset (A cross-sectional study). In addition we repeatedly examined 40 hemiplegic patients until 12 weeks after the onset to define the pattern of change (A prospective study).

Results: There was no significant difference in the score of abnormal spontaneous activities according to the radiologic findings. The score of abnormal spontaneous activities decreased while Brunnstrom stage progressed. In both the cross-sectional and prospective studies, we found that the abnormal spontaneous activities decreased according to the time course after the onset in the limb without RSD, but sustained in the limb with RSD.

Conclusion: Abnormal spontaneous activities decreased according to the progression of Brunnstrom stages. The hemiplegic patients with RSD showed more profuse and sustained abnormal spontaneous activities at needle EMG study of hemiplegic upper limb than the patients without RSD.

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Pudendal Somatosensory Evoked Potential in Korean Women: Reference Values.
Yoon, Kisung , Kim, Sang Beom , Kwak, Hyun , Ha, Nam Jin , Kwon, Heon Young , Cha, Moon Seok
J Korean Acad Rehabil Med 1999;23(2):335-342.

Objective: To obtain reference values of early potential latency and amplitude of pudendal SEP in Korean normal women and to correlate those values with height and age.

Method: Twenty-three normal female with mean age of 45.27 years were evaluated for pudendal SEP. Stimulation was applied on the dorsal aspect of the clitoris with a bar electrode. Onset, P1, N1, P2 latencies and P0-P1, P1-N1, N1-P2 amplitudes were measured and those of both sides were analyzed.

Results: The mean latency of P0, P1, N1, P2 were 29.0⁑2.83 msec, 35.5⁑2.91 msec, 45.1⁑4.10 msec, 56.3⁑5.20 msec by the right pudendal nerve, and 28.6⁑3.11 msec, 35.2⁑2.93 msec, 45.0⁑3.83 msec, 56.5⁑5.33 msec by the left pudendal nerve. The amplitude ranges of P0-P1, P1-N1, N1-P2 were 0.31∼2.45 uV, 0.11∼2.24 uV, 0.21∼2.62 uV by the right pudendal nerve, and 0.29∼2.46 uV, 0.25∼2.21 uV, 0.12∼5.07 uV by the left pudendal nerve. There was tendency of prolongation of the latency with increasing the height. There is no difference of amplitude according to the height and the age. There was no significant difference between right and left sides in mean latency and range of amplitude of pudendal nerve SEPs, and between premenopause and postmenopause.

Conclusion: Normal reference of female pudendal SEP were established. We suggest that pudendal SEP can be used as one of useful diagnostic tools for female urogenital and neurologic disease.

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Quantitative Analysis of Tendon Reflexes of Upper Extremities in Normal Volunteers.
Yoon, Tae Sik , Kim, Jeong Ah
J Korean Acad Rehabil Med 1999;23(2):310-315.

Objective: The purpose of this study was to establish the normal values of tendon reflexes (T-reflex) in upper extremities of normal Korean adults.

Method: T-reflex responses were recorded in 30 normal volunteers by delivering tendon taps with a hand operated electric reflex hammer. From 5 repeated trials of each subject, the shortest onset latency and duration, the largest peak to peak amplitude of compound muscle action potentials were chosen for representative values.

Results:

1) There was no significance in the side-to-side differences for all values.

2) Mean values of latency were 13.8⁑1.1 msec in males, 12.4⁑0.9 msec in females for biceps T-reflex and 13.0⁑1.1 msec in males, 11.3⁑1.0 msec in females for triceps T-reflex and there were significant differences between males and females.

3) Height and upper arm length showed a significant positive correlation with biceps and triceps T-reflex latency (p<0.001).

Conclusion: We believe that our results can be used as a guideline researching the tendon reflexes in upper extremities.

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3-Dimensional Gait Analysis of Korean Adults.
Kwon, Do Youn , Sung, In Young , You, Jong Youn , Ha, Sang Bae
J Korean Acad Rehabil Med 1998;22(5):1107-1113.

Objective: The aim of this study is to present the basic reference data of age and sex specific gait parameters for Korean adults.

Method: The basic gait parameters were extracted from 70 healthy adults, 38 men and 32women, 21 to 69 years of age using VICON 340 Motion Analyzer.

Results: The temporal gait parameters and kinematic parameters of Korean adults were similar to other western reference data.

Conclusion: Significant sex differences exist in the maximal pelvic tilting, pelvic internal rotation and foot internal rotation and plantar flexion. There is a statistically significant age variability for the hip and knee flexion at stance phase.

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Abnormal Spontaneous Activities According to Type of Herniated Lumbar Disc and Anteroposterior Diameter of Dural Sac in MRI.
Cha, Sang Min , Kim, Hee Sang , Ahn, Kyung Hoi
J Korean Acad Rehabil Med 1998;22(4):866-870.

Objective: To assess the abnormal spontaneous activities in needle electromyography (EMG) according to the type of herniated lumbar disc and anteroposterior the diameter of dural sac in magnetic resonance imaging (MRI).

Method: We performed the MRI on 120 patients with low back pain (LBP) and measured the midline anteroposterior diameter of dural sac in a MRI axial view. Fifty patients with a disc protrusion or extrusion in MRI were reviewed for the clinical findings on physical examination and assessed for the abnormal spontaneous activities (ASA) in needle EMG.

Results: Seventy cases with a normal finding in MRI did not have differences in a dural sac diameter regardless their age or sex. Fifty cases with a protrusion or extrusion in MRI showed that the dural sac size decreased more in an extrusion than in a protrusion, and more in a paracentral type than in a central type. The incidence of ASA in a needle EMG increased more in an extrusion than in a protrusion, and more in a paracentral type than in a central type. The incidence also increased according to the decrement of a dural sac diameter. The incidence of ASA were 100% in a group with both motor and sensory signs, 94% in a group with a motor sign, 86% in a group with a sensory sign, 26% in a group without motor or sensory sign.

Conclusion: We concluded that the abnormalities in needle EMG must be correlated with the direction of herniated lumbar disc and anteroposterior diameter of the dural sac in MRI as well as clinical findings.

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Quantitative Measurement of Insertional Activity.
Sohn, Min Kyun , Hong, Ju Hyoung
J Korean Acad Rehabil Med 1997;21(5):912-919.

Analysis of insertional activity is a routine part of the clinical electromyogrphic examination. It provides an information of muscle excitability but it's clinical significance has not perfectively accepted yet. This study was designed to evaluate clinical usefulness of insertional activity through quantitative analysis in the diagnostic field of pathology.

Monopolar needle electrode was inserted briefly in the biceps brachii, paralumbar spinal and tibialis anterior muscles of the normal and denervated muscles. Total duration and spike duration of the insertional activity were measured 10 times in each muscle and averaged. Within spike duration we measured turns, mean amplitude, turns/amplitude, RMS, mean frequency and median frequency.

The measured parameters of insertional activities were not significantly different according to the muscle in normal controls. In denervated muscles, the turns, mean amplitude, RMS, mean frequency and median frequency were decreased but turns/amplitude was increased compared to those of normal controls. But there were no difference in total duration and spike duration between normal and denervated muscles. In denervated muscles the muscle power was positively correlated with turns, mean amplitude, RMS, mean frequency and median frequency, and the grade of abnormal spontaneous activities was inversely correlated with turns, mean amplitude, RMS, mean frequency and median frequency.

Therefore quantitative analysis of insertional activity could be a useful method for the diagnosis of neuromuscular disease.

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