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"Muscle"

Original Articles

Pain & Musculoskeletal rehabilitation

Assessment of Back Muscle Activity Using High-Density Surface Electromyography in Patients With Degenerative Thoracolumbar Kyphosis: A Preliminary Study
Yuki Kurokawa, Yuichi Nishikawa, Noriaki Yokogawa, Takaki Shimizu, Satoru Demura, Satoshi Kato
Ann Rehabil Med 2026;50(1):22-32.   Published online February 23, 2026
DOI: https://doi.org/10.5535/arm.250126
Objective
To examine back muscle activity and fatigue behavior in female patients with degenerative thoracolumbar kyphosis (DTK) using high-density surface electromyography (HDSEMG) and evaluate the effects of using a soft spinal orthosis.
Methods
Seven female participants with DTK (mean age: 73.6 years) were assessed during static standing and a weighted holding task with and without a soft spinal orthosis. HDSEMG signals were obtained from the lumbar erector spinae using a 64-electrode array. Time to fatigue (TTF), spatial displacement, and directional consistency of muscle activation were analyzed using the spatial center of activity (SCoA) and circular variance (CV).
Results
Orthosis use significantly reduced the sagittal vertical axis and low back pain. TTF was significantly prolonged during the weighted holding task with the orthosis (p=0.012), indicating delayed fatigue onset. SCoA displacement was significantly reduced in both tasks (p<0.001), whereas CV analysis demonstrated improved directional consistency of muscle activation.
Conclusion
HD-SEMG revealed early fatigue onset and unstable muscle activation patterns in patients with DTK, particularly during load-bearing tasks performed without orthotic support. Orthosis used improved endurance and neuromuscular efficiency by reducing spatial and directional variability in muscle recruitment. These findings underscore the utility of HDSEMG for elucidating the neuromuscular pathophysiology of DTK and support the use of spinal orthoses as a conservative treatment approach.
  • 1,886 View
  • 58 Download

Pain & Musculoskeletal rehabilitation

Differential Activation of the Multifidus and Erector Spinae During Asymmetric Spinal Stabilizing Exercise in Adolescent Idiopathic Scoliosis
Sangyoung Kim, Jee Hyun Suh, Ju Seok Ryu
Ann Rehabil Med 2026;50(1):1-11.   Published online February 11, 2026
DOI: https://doi.org/10.5535/arm.250148
Objective
To identify the asymmetric spinal stabilizing exercise (ASSE) postures that selectively activate the multifidus (Mu) relative to the erector spinae (ES) in patients with adolescent idiopathic scoliosis (AIS), thereby supporting the development of curve-specific exercise programs for three-dimensional spinal deformities.
Methods
Surface electromyography recordings were obtained bilaterally from the ES and Mu muscles during ASSE postures. Signals were normalized to the maximal voluntary isometric contraction. The asymmetry ratio, Mu/ES ratio, and additional asymmetric contraction of the Mu were analyzed.
Results
The study included 40 patients with AIS. The Mu demonstrated greater ipsilateral activation in the side-lying posture, whereas greater contralateral activation was observed during unilateral lower extremity lifting and combined upper–lower extremity lifting in the prone posture, as well as during combined upper–lower extremity lifting in the bird-dog posture. In the prone and bird-dog postures, the Mu/ES ratio exceeded 1.0, indicating relatively stronger Mu recruitment under rotational loading. Additional asymmetric contraction of the Mu was greatest in the side-lying posture (47%), with differences<15% in all other postures.
Conclusion
ASSE induces posture-specific asymmetric activation of the paraspinal muscles in patients with AIS. Although the side-lying posture produced the largest asymmetry, this reflected increased ES activity for trunk elevation rather than true selective Mu contraction. In contrast, the prone and bird-dog postures demonstrated a greater Mu contribution relative to the ES under rotational loading. These findings suggest that ASSE can be adapted to target specific paraspinal muscle components: side lying for lateral bending and bird-dog variations to enhance rotational stability.
  • 1,539 View
  • 72 Download
  • 1 Web of Science

Physical therapy

Comparing Multiple Versus Sustained Insertion Dry Needling Therapy for Myofascial Neck Pain: A Randomized Controlled Trial
Gracjan Olaniszyn, Adrian Kużdżał, Adam Kawczyński, Filip Matuszczyk, Kamil Gałęziok, Filipe Manuel Clemente, Robert Trybulski
Ann Rehabil Med 2025;49(4):208-225.   Published online August 29, 2025
DOI: https://doi.org/10.5535/arm.250052
Objective
To compare the Hong (GH) and sustained insertion (GS) dry needling methods in patients with myofascial neck pain, this experimental study was conducted.
Methods
A randomized controlled trial included 30 participants, assigned to either the GH (n=15) or GS (n=15) group. Each group received treatment on either the right or left side, with one side receiving experimental DN and the other receiving control (sham) DN. The GS method involved a single needle insertion per myofascial trigger point for one minute, while the GH method used multiple rapid needle insertions over two minutes without needle retention. Measurements were taken before therapy, 5 minutes post-DN session (post-5min), 24 hours post-session (post-24h), and 7 days post-session (post-7d). Muscle tension (MT) and muscle stiffness (MS) were measured with a myotonometer, pressure pain threshold (PPT) with an algometer, maximum isometric strength (Fmax) with a handheld dynamometer, and transcutaneous perfusion (PU) with laser Doppler flowmetry. Power Doppler Score (PDS) and minor adverse events were also recorded.
Results
Results showed that GH led to significantly higher MT and MS values at post-24h and post-7d (p<0.001). In contrast, GS showed greater PPT and Fmax at post-5min, post-24h, and post-7d (p<0.001). Additionally, GH exhibited higher PU values at post-5min and post-7d (p<0.001), while GS showed higher PDS values at post-5min and post-24h (p<0.001).
Conclusion
The GH method resulted in less favorable outcomes in terms of MT and MS, while the GS method showed superior improvements in pain relief and functional recovery.

Citations

Citations to this article as recorded by  
  • Clinical impact and relevance of dry needling site location in the management of chronic neck pain: a randomized controlled trial
    Fernando Piña-Pozo, Hermann Fricke-Comellas, Ángel Oliva Pascual-Vaca, Félix Paredes-López, Ana Isabel Hueso-Pérez, Alberto Marcos Heredia-Rizo
    Journal of Manual & Manipulative Therapy.2026; 34(4): 320.     CrossRef
  • Dry Needling Versus Kinesiotaping for Upper Trapezius Trigger Points: A Randomized Controlled Trial
    Hira Younis, Mohammad Ali Khan, Imrana Aziz
    Healer Journal of Biomedical and Health Sciences.2026; 2(1): 8.     CrossRef
  • Dry needling frequency and its effect on pain and disability in acute cervical myofascial pain: a multicenter study
    Gracjan Olaniszyn, Adrian Kużdżał, Filipe Manuel Clemente, Ana Filipa Silva, Robert Trybulski
    Annals of Physical and Rehabilitation Medicine.2026; 69(5): 102112.     CrossRef
  • 4,124 View
  • 108 Download
  • 2 Web of Science
  • 3 Crossref

Physical therapy

Unilateral Vibratory Stimulation Inhibits Contralateral Spinal Anterior Horn Cells in Homonymous Muscles for the First 75 Seconds
Kenta Kunoh, Takahiro Takenaka, Daisuke Kimura, Toshiaki Suzuki
Ann Rehabil Med 2025;49(4):226-233.   Published online August 22, 2025
DOI: https://doi.org/10.5535/arm.240107
Objective
To investigate muscle tone changes over time in contralateral homonymous muscles when unilateral muscles are stimulated, using F-wave measurements, we examined whether vibratory stimulation on the contralateral homonymous muscle of the affected side may reduce spasticity, whose optimal duration remains unclear.
Methods
Vibratory stimulation was applied to the right hand of healthy adults, using parameters of 80 Hz frequency, 0.4 mm amplitude, 400 g load, and 195 seconds of duration on the abductor digiti minimi muscle. F-wave was measured in the left hand before stimulation, at seven intervals during stimulation, and immediately after.
Results
The F/M amplitude ratio decreased immediately at stimulation onset, at 30 seconds, and at 60 seconds compared to baseline. A least-squares analysis revealed a negative slope from baseline to 60 seconds (f(x)=-0.11x+1.12), while the slope became positive after 90 seconds, continuing after stimulation ended (f(x)=0.04x+0.82).
Conclusion
Unilateral vibratory stimulation may decrease excitability in the spinal anterior horn cells of the contralateral homonymous muscle for up to 75 seconds post-stimulation, suggesting a potential mechanism for spasticity management.
  • 3,308 View
  • 61 Download

Review Article

Spinal cord injury

The Effects of Inspiratory Muscle Training in Individuals With Cervical Spinal Cord Injuries: A Systematic Review and Meta-Analysis
Dat Huu Tran, Ha Thi Le, Tho Thi Quynh Chu, Hung Thi Cam Pham, Anh Ngoc Van Le
Ann Rehabil Med 2025;49(3):152-163.   Published online June 17, 2025
DOI: https://doi.org/10.5535/arm.250013
Correction in: Ann Rehabil Med 2025;49(4):257
The effect of inspiratory muscle training (IMT) on cervical spinal cord injury (SCI) remains controversial. This study aimed to assess the efficacy of IMT in enhancing breathing muscle strength, pulmonary function, and quality of life (QoL) among patients with cervical SCI. A search was performed using the PubMed, Cochrane Library, Scopus, Embase, and Web of Science databases through December 2023. This review was conducted according to PRISMA guidelines and the Cochrane Library Handbook. The meta-analysis used mean differences (MDs) or standardized mean differences to pool the results. The Risk of Bias 2 and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) were used to assess the methodological quality of the included studies. This systematic review included five randomized controlled trials (202 participants). The results of the meta-analysis showed that IMT significantly improved maximal inspiratory pressure (MIP) with MD 12.13 cmH2O (95% confidence interval [CI] 4.22 to 20.03), maximal expiratory pressure (MEP) with MD 8.98 cmH2O (95% CI 6.96 to 11.00), and vital capacity (VC) with MD 0.25 L (95% CI 0.21 to 0.28). There were no significant improvements in forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and QoL. The quality of the evidence ranged from very low to moderate, owing to bias and heterogeneity. Our results showed that IMT may improve MIP, MEP, and VC, but not FEV1, FVC, or QoL, in patients with cervical SCI. Further large-scale studies are required to determine this effect’s optimal dosage and duration.

Citations

Citations to this article as recorded by  
  • Rewiring the Lung–CNS Axis After Spinal Cord Injury
    HaiRong Wu, Xiaolong Li, Wenjun Zhao, Yihan Li, Hang Zhang, Heng Yin, Xiaofeng Gu
    Journal of Inflammation Research.2026; Volume 19: 1.     CrossRef
  • Effects of whole-body vibration training on sarcopenia in older adults: a systematic review and meta-analysis of randomized controlled trials
    Jaewon Beom, Jae-Young Lim, Sang Yoon Lee
    Scientific Reports.2026;[Epub]     CrossRef
  • RESPIRATORY MUSCLE TRAINING IN SPORTS AND REHABILITATION: A LITERATURE REVIEW
    Martyna Łubianka, Wiktor Słyś
    International Journal of Innovative Technologies in Social Science.2026;[Epub]     CrossRef
  • Effects of Electrostimulation With the Laparoscopic Implantation of Neuroprosthesis Procedure Combined With Cardiorespiratory Physiotherapy on the Functional Rehabilitation of Individuals With Chronic Spinal Cord Injury: Quasirandomized Prospective Contro
    Wellington Contiero, Augusta Ribeiro Morgado, Victor Croos-Bezerra, Cristiano Soares Simões, João Angelo Ferres Brogin, Jean Faber, Nucelio Lemos
    Neuromodulation: Technology at the Neural Interface.2026;[Epub]     CrossRef
  • Determinants for improving respiratory muscle training after spinal cord injury using real-world clinical data
    Gabi Mueller, Marianne Tanner, Amelie Gruber, Sabrina Alessandri, Claudio Perret, Andreas Limacher
    Spinal Cord.2026;[Epub]     CrossRef
  • 13,081 View
  • 196 Download
  • 3 Web of Science
  • 5 Crossref

Original Articles

Cardiopulmonary rehabilitation

Would Integrating Inspiratory Muscle Training into Pulmonary Rehabilitation of Adults with Burn Injuries Have Any Advantageous Effects? a Randomized, Double-Blind, Sham-controlled Study
Nabil Mahmoud Abdel-Aal, Maged A. Basha, Saleh M. Aloraini, Alshimaa R. Azab, FatmaAlzahraa H. Kamel
Ann Rehabil Med 2025;49(1):30-39.   Published online February 28, 2025
DOI: https://doi.org/10.5535/arm.240092
Objective
To determine the effectiveness of adding inspiratory muscle training (IMT) alongside a pulmonary rehabilitation protocol in terms of inspiratory muscle strength, lung function, and exercise capacity in burned adults.
Methods
A randomized, double-blinded, sham-controlled study. Fifty-two adult patients with burn injuries, more than 20 years old and at least 20% total body surface area, were assigned randomly either to the experimental or the conventional group. The participants in the experimental group were given IMT plus a pulmonary rehabilitation program; the conventional group received only a pulmonary rehabilitation program. The interventions were performed for 8 weeks. At the beginning and after 8 weeks of training, the respiratory muscles’ strength, lung function and exercise capacity were all examined.
Results
After 2 months of training, the experimental group demonstrated statistically significant improvements than conventional group in maximum inspiratory pressure, maximum expiratory pressure, 6-minute walk test, forced vital capacity, and forced expiratory volume in 1 second (p<0.05).
Conclusion
An 8-week IMT program coupled with pulmonary rehabilitation increases respiratory muscle strength, pulmonary functions, and functional capacity in burn patients. IMT is a beneficial and efficient therapy that can be easily implemented for burn patients.

Citations

Citations to this article as recorded by  
  • The Effect of Inspiratory Muscle Training on Fatigue Among Burn Patients in Iraq
    Zahraa Fayyadh Abd Hussein Al-Amiri, Alaa Jawad Kadhim, Hadi Ahmadi Chenari, Steven L. Baumann
    Nursing Science Quarterly.2026;[Epub]     CrossRef
  • 5,684 View
  • 94 Download
  • 1 Web of Science
  • 1 Crossref

Neuromuscular disorders

Muscle Pathology Associated With Cardiac Function in Duchenne Muscular Dystrophy
Jin A Yoon, Heirim Lee, In Sook Lee, You Seon Song, Byeong-Ju Lee, Soo-Yeon Kim, Yong Beom Shin
Ann Rehabil Med 2024;48(6):405-412.   Published online December 16, 2024
DOI: https://doi.org/10.5535/arm.240006
Objective
To compare the progression of muscle fibrosis of various site and its relation between cardiac deterioration in Duchenne muscular dystrophy (DMD). In this study aimed to examine the associations between echocardiogram-based cardiac function indices and fibrosis of the abdominal and lower extremity muscles in patients with DMD to facilitate early detection of cardiac dysfunction and identify its predictors.
Methods
Twenty-one patients with DMD patients were enrolled in the study. The association between cardiac dysfunction and fibrosis of the abdominal and lower extremity muscles was determined by analyzing the echocardiography and elastography. Non-parametric Spearman rank correlation coefficients were used to examine the pairwise relationships between cardiac function and muscle elasticity.
Results
All patients were male and non-ambulant. Their mean age was 18.45±4.28 years. The strain ratios of the abdominal muscle and quadriceps muscles were significantly higher than those of the medial gastrocnemius. The strain ratio of the rectus abdominis muscle has a significant negative correlation with left ventricular ejection fraction. Cardiac function and valvular insufficiency were not significantly correlated with muscle strain ratio. According to the result of our study, the only skeletal muscle which showed significant correlation with cardiac dysfunction was degree abdominal muscle fibrosis.
Conclusion
The degree of fibrosis of respiratory muscles was also significantly associated with cardiac dysfunction; therefore, it can be used as a predictor of cardiac dysfunction in patients with DMD in clinical practice.

Citations

Citations to this article as recorded by  
  • Impact of functional status in patients with muscular dystrophy-associated cardiomyopathy on survival after heart transplantation
    Sanath Patil, Nayeem Nasher, T. Reese Macmillan, Daler Rahimov, Eugene Storozynsky, J. Eduardo Rame, Keshava Rajagopal, John W. Entwistle, Charles W. Hoopes, Vakhtang Tchantchaleishvili
    Expert Review of Cardiovascular Therapy.2025; 23(10): 625.     CrossRef
  • 5,330 View
  • 75 Download
  • 1 Web of Science
  • 1 Crossref

Physical Therapy

The Assessment of Muscle Strength and Cardiorespiratory Parameters Using Simple Tests in Older Adults With Recovery From Mild COVID-19
Patchareeya Amput, Sirima Wongphon
Ann Rehabil Med 2024;48(6):389-395.   Published online December 10, 2024
DOI: https://doi.org/10.5535/arm.240033
Objective
To evaluate muscle strength and cardiorespiratory parameters, this study uses simple tests in older adults, including those who have and have not recovered from mild coronavirus disease 2019 (COVID-19).
Methods
Eighty older adults (age≥60 years old) were divided into two groups: those without previous COVID-19 (control group, n=40) and those with recovery from mild COVID-19 (recovered group, n=40). Muscle strength was assessed using a handgrip strength test and the sit-to-stand test (STS10). Cardiorespiratory parameters were evaluated with a 1-minute sitto- stand (1-min STS) test and a 6-minute walk test (6MWT).
Results
Both groups had normal values for body mass index, blood pressure, heart rate, and pulse oxygen saturation. The recovered group showed significant differences in handgrip strength test (24.73±6.99 vs. 22.03±4.36, p=0.041) and duration for the STS10 (25.15±6.11 vs. 33.40±7.56, p<0.001) when compared to the control group. Furthermore, the recovered group had significantly decreased repetitions of a 1-min STS (31.38±4.89 vs. 21.25±3.64, p<0.001) and increased the rate of perceived exertion (RPE) (7.43±1.20 vs. 8.95±1.01, p=0.01) and leg fatigue (1.49±1.13 vs. 3.00±1.04, p=0.03) after performing a 1-min STS when compared with the control group. Moreover, the recovered group had also significantly decreased distances for the 6MWT (421.68±8.28 vs. 384.35±6.17, p<0.001) and increased the post-test RPE (7.63±1.37 vs. 12.05±1.63, p<0.001) and the post-test leg fatigue (1.71±0.88 vs. 5.28±0.91, p<0.001) compared with the control group.
Conclusion
Older adults with recovery from mild COVID-19 reported reduced muscle strength and exercise tolerance when compared with older adults without COVID-19.
  • 5,105 View
  • 56 Download
  • 1 Web of Science

Review Articles

Neuromuscular disorders

Effectiveness of Non-Pharmacological Interventions for Spasticity Management in Multiple Sclerosis: A Systematic Review
Bhasker Amatya, Fary Khan, Krystal Song, Mary Galea
Ann Rehabil Med 2024;48(5):305-343.   Published online October 31, 2024
DOI: https://doi.org/10.5535/arm.240064
This systematic review aims to determine the effectiveness of non-pharmacological interventions for the management of spasticity in people with multiple sclerosis (pwMS). A comprehensive literature search in health science databases (MEDLINE, Embase, CENTRAL, CINHAL) was performed to identify randomized controlled trials (RCTs) (up to April 2024). Manual searching in journals and screening of the reference lists of identified studies were conducted. Two authors independently selected the studies, assessed the methodological quality, and summarized the evidence. A meta-analysis was not feasible due to the methodological, clinical, and statistical diversity of the included studies. Overall, 32 RCTs (n=1,481 participants) investigated various types of non-pharmacological interventions including: physical activity, transcranial magnetic stimulation (intermittent theta burst stimulation [iTBS], repetitive transcranial magnetic stimulation [rTMS]), electromagnetic therapy, transcutaneous electrical nerve stimulation, vibration therapy, shock wave therapy, self-management educational programs, and acupuncture. All studies scored ‘low’ on the methodological quality assessment, implying a high risk of bias. The findings suggest ‘moderate to low certainty’ evidence for physical activity programs used in isolation or combination with other interventions (pharmacological or non-pharmacological), and for iTBS/rTMS with or without adjuvant exercise therapy in improving spasticity in adults with MS. There is ‘very low certainty’ evidence supporting the use of other modalities for treating spasticity in this population. Despite a wide range of non-pharmacological interventions used for the management of spasticity in pwMS, there is a lack of conclusive evidence for many. More robust trials with larger sample sizes and longer-term follow-ups are needed to build evidence for these interventions.

Citations

Citations to this article as recorded by  
  • Development and validation of a practical documentation of inpatient rehabilitation goals, therapy content and outcomes for improving mobility in people with multiple sclerosis in Austria: A multicentre single-arm pragmatic clinical trial
    Andreas Wanitschek, Barbara Seebacher, Barbara Linert, Andreas Mühlbacher, Robert Hatschenberger, Nicole Kranawetter, Lisa Tischler, Monika Scarpatetti, Verena Walder, Alexandra Holzinger, Bernhard Haider, Doris Hörtenhuber, Eva Kronberger-Schaffer, Vikto
    Multiple Sclerosis and Related Disorders.2026; 109: 107100.     CrossRef
  • The effect of the EXOPULSE Mollii suit on motor functions in patients with multiple sclerosis – a randomized sham-controlled crossover trial
    Samar S Ayache, Joseph G Mattar, Alain Créange, Mohamed Abdellaoui, Mickael Zedet, Jean-Pascal Lefaucheur, Hana Megherbi, Hayfa Khaled, Georges Naïm Abi Lahoud, Moussa A Chalah
    Multiple Sclerosis Journal – Experimental, Translational and Clinical.2025;[Epub]     CrossRef
  • Efeito agudo do ultrassom no padrão espástico do bíceps braquial em indivíduos com distúrbios neurológicos
    João Sávio Carneiro Silva, Letícia Costa Mengoni, Gabriel Pádua da Silva, Wellington Marcelo Queixas Moreira, Oswaldo Luiz Stamato Taube, Bruno Ferreira
    RCMOS - Revista Científica Multidisciplinar O Saber.2025;[Epub]     CrossRef
  • Balancing innovation and affordability in relapsing-remitting multiple sclerosis: a budget impact analysis from Saudi Arabia
    Ahmed Al-Jedai, Hajer Almudaiheem, Faisal Al-Suweidan, Mohamed al Jumah, Ahmed al-Thobaiti, Fahad Alzureiqan, Wejdan Abu Ras, Fahad M. Al-Dosari, Yaser Al Malik, Pratik Dhopte, Rita Ojeil
    Frontiers in Public Health.2025;[Epub]     CrossRef
  • Trigeminal neuralgia in multiple sclerosis patients: a systematic review and meta-analysis of minimally invasive surgical procedures, decompression, and the pain outcomes
    Daniel Encarnación-Santos, Gennady Chmutin, Nazmin Ahmed, Egor Chmutin, Emmanuel Batista-Geraldino, Bipin Chaurasia
    Headache Medicine.2025; 16(4): 244.     CrossRef
  • 17,509 View
  • 233 Download
  • 3 Web of Science
  • 5 Crossref

Neuromuscular disorders

The impact of disease-modifying therapy ranges from cure to no impact with a wide range of intermediates. In cases where the intermediate group reaches a plateau after the acquisition of some muscle strength, it is necessary to set a functional level appropriate for increased motor power and establish a long-term exercise plan to maintain it. As the disease status stabilizes and the life span increases, early nonsurgical interventions are required, such as using a standing frame to prevent joint contracture, applying a spinal brace at the early stage of scoliosis, and maintaining sitting postures that exaggerate lumbar lordosis. In cases where scoliosis and hip displacement occur and progress even after conservative managements are implemented, early referral to surgery should be considered. Oromotor activity and swallowing function are influenced not only by the effects of disease-modifying drugs, but also by post-birth experience and training. Therefore, although the feeding tube cannot be removed, it is necessary to make efforts to simulate the infant feeding development while maintaining partial oral feeding. Since the application period of non-invasive ventilators has increased, it has become more important to prevent long-term complications such as facial abrasion, skin allergy, orthodontic deformities, and maxillary flattening caused by the interface. Dual ventilator mode or interface can also be utilized.

Citations

Citations to this article as recorded by  
  • Immediate and Sustained Effects of Intensive Equine-Assisted Physiotherapy Based on Neuroproprioceptive “Facilitation and Inhibition” on Psychomotor Development, Clinical Functions, Quality of Life, and Molecular Biological Indicators in Children With Spi
    Katerina Marikova, Jindra Reissigova, Miloslav Vilimek, Marie Cerna, Marketa Pokorna, Kamila Rasova
    JMIR Research Protocols.2026; 15: e83266.     CrossRef
  • Skeletal muscle in spinal muscular atrophy: Critical insights from pathogenesis to therapeutic strategies
    Linda Ottoboni, Chiara Panicucci, Giulia Magni, Delia Gagliardi, Michela Ripolone, Laura Napoli, Maurizio Moggio, Giacomo Pietro Comi, Claudio Bruno, Stefania Paola Corti
    Neurobiology of Disease.2026; 221: 107324.     CrossRef
  • The role of rehabilitation in the development of motor skills in patients with spinal muscular atrophy 5q receiving pathogenetic therapy
    Yuliya O. Papina, Aleksandr R. Stevanovich, Evgeniya A. Melnik, Svetlana B. Artemyeva, Dmitry V. Vlodavets
    L.O. Badalyan Neurological Journal.2026; 6(4): 209.     CrossRef
  • The role of rehabilitation in the development of motor skills in patients with spinal muscular atrophy 5q receiving pathogenetic therapy
    Yuliya O. Papina, Aleksandr R. Stevanovich, Evgeniya A. Melnik, Svetlana B. Artemyeva, Dmitry V. Vlodavets
    L.O. Badalyan Neurological Journal.2026; 6(4): 209.     CrossRef
  • Persistent deficits in the motor unit following mono and dual administration of SMN up-regulators in the SmnΔ7 mouse model of spinal muscular atrophy
    Inga Partlova, Laura H. Comley, Alice E. Haigh, Paloma Serena Tarodo, Lyndsay M. Murray
    Experimental Neurology.2026; 404: 115898.     CrossRef
  • Short-term and long-term outcomes of transcutaneous spinal cord stimulation in SMA: findings from consecutive courses
    Natalia Shamantseva, Anton Novikov, Maria Maldova, Ivan Shalmiev, Margarita Bystrova, Natalia Krutikova, Tatiana Moshonkina
    Journal of Neural Engineering.2026; 23(4): 046013.     CrossRef
  • Physical and Respiratory Rehabilitation in Spinal Muscular Atrophy: A Critical Narrative Review
    Serena Cammarano, Vincenzo Alessio Chirico, Benedetto Giardulli, Giovanna Mazzuoccolo, Carlo Ruosi, Bruno Corrado
    Applied Sciences.2025; 15(8): 4398.     CrossRef
  • Treatment Guidelines and Rehabilitation in Spinal Muscular Atrophy and Duchenne’s Muscular Dystrophy
    Eleni Drakou, Sarah Wright, Leslie D. Delfiner, David Cancel
    Physical Medicine and Rehabilitation Clinics of North America.2025; 36(3): 531.     CrossRef
  • Management of Hip and Spine in Neuromuscular Disorders
    Unwana Abasi, Abigail Allen, Coral Candelario-Velazquez, Sheena Ranade, David Cancel
    Physical Medicine and Rehabilitation Clinics of North America.2025; 36(3): 429.     CrossRef
  • Multimodal Analysis of Biomarkers for SMA - Data from the First Six-Month Nusinersen Follow-Up
    Corina Sporea, Mihaela Axente, Gabriel Cristian Bejan, Andrada Mirea, Mihaela Badina
    Balneo and PRM Research Journal.2025; 16(Vol 16 No.): 883.     CrossRef
  • The effect of thoracolumbosacral orthosis on scoliosis progression and chest deformity in children with type 1 spinal muscular atrophy: A randomized controlled trial
    Emre Dansuk, Ayşe Nur Tunalı Van Den Berg, Görkem Ata, Seval Kutluturk Yıkılmaz, Sedat Oktem, Taher Babaee
    PLOS One.2025; 20(9): e0323341.     CrossRef
  • Spinal Muscular Atrophy (SMA)
    Kaitlyn Rodriguez, Mara Karamitopoulos
    Operative Techniques in Orthopaedics.2025; 35(3): 101213.     CrossRef
  • 10,891 View
  • 257 Download
  • 12 Web of Science
  • 12 Crossref

Original Article

Cardiopulmonary rehabilitation

Effect of Pre- and Post-Dialysis Exercise on Functional Capacity Using Portable Ergometer in Chronic Kidney Disease Patients
Tae-Seok Chae, Da-Sol Kim, Myoung-Hwan Ko, Yu Hui Won
Ann Rehabil Med 2024;48(4):239-248.   Published online August 30, 2024
DOI: https://doi.org/10.5535/arm.240005
Objective
To assess whether performing exercises during hemodialysis reduces the risk of developing intradialytic hypotension and enhances exercise capacity in patients with chronic kidney disease.
Methods
This study included patients aged ≥18 years undergoing hemodialysis. Participants performed exercises using a portable lower extremity ergometer during hemodialysis sessions for 3 weeks. Data regarding walking distance, knee strength, quality of life, fat-free mass, arterial pressure, blood pressure, heart rate, frequency of intradialytic hypotension, fatigue, and duration of hemodialysis were collected and analyzed.
Results
Significant improvements in walking distance and knee strength were observed following the implementation of exercise training during hemodialysis. Although there was no significant reduction in the frequency of intradialytic hypotension, a decreasing trend was noted. Other parameters such as quality of life and fatigue did not show significant changes.
Conclusion
Using a portable ergometer during hemodialysis improved exercise capacity and knee strength in patients with chronic kidney disease. There was a trend toward reduced intradialytic hypotension, suggesting potential cardiovascular benefits. Further research with larger sample sizes is needed to confirm these findings.

Citations

Citations to this article as recorded by  
  • Resistance Training Improves Fluid Imbalance Symptoms in Hemodialysis Patients: A Randomized Controlled Trial
    Fatemeh Pourmahdigholi
    Journal of Clinical Nephrology.2026; 10(1): 008.     CrossRef
  • What Is the Optimal Timing for Intradialytic Resistance Exercise? A Randomized Controlled Trial
    Ömer Bingölbali, Semra Oğuz
    Archives of Physical Medicine and Rehabilitation.2026;[Epub]     CrossRef
  • Pre-hemodialysis exercise training improves systemic aerobic capacity and platelet bioenergetic efficiency in patients with end-stage renal disease
    Yu-Ting Lin, Shu-Chun Huang, Sheng-Chiao Peng, Ching-Chung Hsiao, Ji-Tseng Fang, Jong-Shyan Wang
    Life Sciences.2026; 396: 124403.     CrossRef
  • Can exercise reduce fatigue in people living with kidney disease?
    Thomas J. Wilkinson, Lisa Ancliffe, Jamie H. Macdonald
    Current Opinion in Clinical Nutrition & Metabolic Care.2025; 28(3): 200.     CrossRef
  • Effect of intra-dialytic exercise on hemodialysis session adequacy and solutes clearance and rebound in prevalent hemodialysis patients
    Howaida Elshinnawy, Hisham Elsayed, Hayam Hebah, Waleed Abdelmohsen, Dina Farrag, Mostafa Abdelnasier
    Egyptian Rheumatology and Rehabilitation.2025;[Epub]     CrossRef
  • 8,286 View
  • 158 Download
  • 3 Web of Science
  • 5 Crossref

Review Article

Spinal cord injury

Effects of Botulinum Toxin-A for Spasticity and Nociceptive Pain in Individuals with Spinal Cord Injury: A Systematic Review and Meta-Analysis
Dewan Md. Sumsuzzman, Zeeshan Ahmad Khan, Irin Sultana Nila, Vanina Myuriel Villagra Moran, Madhuvilakku Rajesh, Won Jong Yang, Yonggeun Hong
Ann Rehabil Med 2024;48(3):192-202.   Published online June 28, 2024
DOI: https://doi.org/10.5535/arm.240034
We conducted a systematic review and meta-analysis to examine the protective effects of botulinum toxin-A (Botox-A) on spasticity and nociceptive pain in individuals with spinal cord injuries (SCIs). PubMed, Embase, and Cochrane Library databases were searched from inception to July 2023. The primary outcome of interest was spasticity and nociceptive pain. We pooled the available data using the generic inverse variance method, and we used a fixed-effect/random-effects model. We then calculated standardized mean difference (SMD) and 95% confidence intervals (95% CIs) to estimate the effect size. A total of fourteen studies meeting the inclusion criteria comprised two randomized controlled trials, five pre-post studies, and seven case reports. Across the various study designs, the majority of trials were assessed to have fair to high quality. The meta-analysis shows that Botox-A significantly decreased spasticity (SMD, -1.73; 95% CI, -2.51 to -0.95; p<0.0001, I2=48%) and nociceptive pain (SMD, -1.79; 95% CI, -2.67 to -0.91; p<0.0001, I2=0%) in SCI patients. Furthermore, Botox-A intervention improved motor function, activities of daily living (ADL), and quality of life. Our study suggests that Botox-A may alleviate spasticity and nociceptive pain in SCI patients. Moreover, the observed improvements in motor function, ADL, and overall quality of life following Botox-A intervention underscore its pivotal role in enhancing patient outcomes.

Citations

Citations to this article as recorded by  
  • Botulinum Toxin for Spasticity: Real-World Effects on Patient Health-Related Quality of Life and Caregiver Burden -A Long-Term Retrospective Study
    Giorgio Mandalà, Maria Luisa Capuana, Giacomo Fisco, Giuliana Grimaldi, Provvidenza Sansone, Maria Silvia Mangano
    Applied Medical Research.2026; 13(4): 1.     CrossRef
  • Botulinum Toxin for Spasticity: Real-World Effects on Patient Health-Related Quality of Life and Caregiver Burden -A Long-Term Retrospective Study
    Giorgio Mandalà, Maria Luisa Capuana, Giacomo Fisco, Giuliana Grimaldi, Provvidenza Sansone, Maria Silvia Mangano
    Applied Medical Research.2026; 13(4): 1.     CrossRef
  • Benefits of Incobotulinumtoxin A in Pain, Spasticity and Functionality—A 5 Years Review
    André Cruz
    Toxins.2026; 18(7): 291.     CrossRef
  • Novel approaches for drug development against chronic primary pain: A systematic review
    Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes
    British Journal of Pharmacology.2025;[Epub]     CrossRef
  • Combined Extracorporeal Shock Wave Therapy and Botulinum Toxin Injection for Spasticity in the Acute Phase of Spinal Cord Injury: A Case Report
    Maiko Nishimura, Risa Harada, Takumi Hirabayashi, Yuka Muranaka, Toshiki Usui, Mariko Nagase, Ryoga Kashima, Wataru Saho, Ryo Yoshikawa, Yoshitada Sakai
    Progress in Rehabilitation Medicine.2025; 10: n/a.     CrossRef
  • 11,087 View
  • 157 Download
  • 3 Web of Science
  • 5 Crossref

Original Articles

Pain & Musculoskeletal rehabilitation

Measurement of Knee Extensor Torque During Repetitive Peripheral Magnetic Stimulation: Comparison of the Forces Induced by Different Stimulators
Masanori Kamiue, Akio Tsubahara, Tomotaka Ito, Yasuhiro Koike
Ann Rehabil Med 2024;48(3):203-210.   Published online May 8, 2024
DOI: https://doi.org/10.5535/arm.230025
Objective
To investigate the factors that induce strong contractions during repetitive peripheral magnetic stimulation (rPMS) and compare the muscle torque induced by two stimulators (Stim A and Stim B) with different coil properties.
Methods
rPMS was applied to the right vastus lateralis of 30 healthy young adults. Stim A contained a 10.1 cm2 rectangular iron core coil, while Stim B contained a 191 cm2 round coil. The knee extensor torque (KET) induced by rPMS at 30 Hz was measured isometrically and divided by the maximum voluntary contraction (MVC) to obtain a relative value of MVC (%MVC). KET at 100% intensity of Stim A (A100%, 1.08 T) was compared to those at 100% or 70% intensity of Stim B (B100%, 1.47 T vs. B70%, 1.07 T). Additionally, we conducted a comprehensive literature search for studies that measured the KET during rPMS.
Results
Both the mean values of %MVC using B100% and B70% were significantly greater than that using A100%. Furthermore, the KET induced by Stim B was found to be larger than that described in previous reports, unless booster units were used to directly stimulate the main trunk of the femoral nerve.
Conclusion
Stim B induced a stronger muscle contraction force than Stim A did. This may be because the larger the coil area, the wider the area that can be stimulated. Additionally, a circular coil allows for deeper stimulation.
  • 6,891 View
  • 96 Download

Brain disorders

Changes in Lower Extremity Muscle Quantity and Quality in Patients with Subacute Stroke
Da Hye Kim, Eun Sol Cho, Young Sook Park, Hyun Jung Chang, Jin Gee Park, Jae Yeon Kim, Jeong Hwan Lee
Ann Rehabil Med 2023;47(6):493-501.   Published online December 1, 2023
DOI: https://doi.org/10.5535/arm.23091
Objective
To analyze the changes in muscle mass and quality with time on the paretic and non-paretic sides in subacute stroke patients and identify correlations between the variation of muscle mass and quality and lower limb functions.
Methods
Thirty hemiplegia patients diagnosed with stroke participated in this study. To evaluate poststroke muscle changes, longitudinal measurement of muscle mass and quality was conducted with bilateral lower limbs. The elastic shear modulus was measured using shear wave elastography and muscle thickness (MT) of rectus femoris, vastus intermedius, vastus lateralis (VL), vastus medialis, tibialis anterior, and gastrocnemius (GCM) muscles. Functional evaluation was performed using Berg Balance Scale (BBS), Five Times Sit to Stand Test (FTSST). Follow-up was performed at discharge. The muscle mass and quality were compared according to time. We analyzed whether muscle quantity and quality were related to function.
Results
MT demonstrated no significant change with time. The elastic shear modulus increased significantly in the paretic VL and GCM muscles and did not change significantly in the muscles on the non-paretic side. Correlation analysis detected that elastic shear modulus in the VL has a cross-sectional negative relationship between BBS and positive relationship between FTSST. There were significant correlation between variation of FTSST and the variation of the elastic shear modulus in VL.
Conclusion
Only paretic VL and GCM muscle quality changed in subacute stroke patients and muscle’s property related to lower limb functions. Therefore, the lower extremity requires an approach to muscle quality rather than quantity for subacute stroke patients.

Citations

Citations to this article as recorded by  
  • Effect of end-effector robot training on lower limb motor function and balance in stroke patients: a systematic review and meta-analysis
    Zejian Lou, Fuhai Wang, Difu Guan, Zhichuan Hu, Chen Wei, Xiaoquan Zhang
    Frontiers in Neurology.2026;[Epub]     CrossRef
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    Dong Hyun Kim, Yoon-Hee Choi, JooHee Lee, Sang Yoon Lee
    BMC Geriatrics.2026;[Epub]     CrossRef
  • Nutritional status, abdominal muscle thickness, and functional outcomes in patients with subacute to chronic stroke
    Esra Şahingöz Bakırcı, Yasin Coşkun, Tuğba Alışık
    Frontiers in Neurology.2026;[Epub]     CrossRef
  • Evaluating muscle characteristics and fall events: insights from real-world longitudinal data
    Shaofang Li, Juchuan Dong, Caixia Zhao, Yongmei Li, Wenyuan Wang, Lijuan An, Yongqian Han, Fuhou Zhang, Lihua Jin
    Annals of Medicine.2025;[Epub]     CrossRef
  • Association Between Electrophysiological Evaluation and Muscle Quality Changes in the Lower Limb of Subacute Stroke Patients: A Pilot Longitudinal Observational Study
    Se Jin Kim, Jeong Hwan Lee, Young Sook Park, Hyun Jung Chang, Jin Gee Park, Eun Sol Cho, Jae Yeon Kim, Dong Jin Ha
    Diagnostics.2025; 15(22): 2854.     CrossRef
  • Effects of Squat Exercise on Stable and Unstable Support Surfaces on Lower-Limb Muscle Thickness and Pennation Angle in Patients with Stroke
    Huiju Nam, Wan-hee Lee
    Archives of Orthopedic and Sports Physical Therapy.2025; 21(2): 61.     CrossRef
  • Efficacy of robot-assisted gait training on lower extremity function in subacute stroke patients: a systematic review and meta-analysis
    Miao-miao Hu, Shan Wang, Cai-qin Wu, Kun-peng Li, Zhao-hui Geng, Guo-hui Xu, Lu Dong
    Journal of NeuroEngineering and Rehabilitation.2024;[Epub]     CrossRef
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  • 122 Download
  • 6 Web of Science
  • 7 Crossref

Pain & Musculoskeletal rehabilitation

The Relationship Between Low Back Pain and Sagittal Spinal Alignment and Back Muscle Mass in Korean Fishery Workers
Minjung Kook, Insuh Kim, Jeongyeon Seo, Hyundong Kim, Heesung Nam, Nami Han
Ann Rehabil Med 2023;47(6):459-467.   Published online November 22, 2023
DOI: https://doi.org/10.5535/arm.23075
Objective
To investigate the relationship between low back pain (LBP) and sagittal spino-pelvic parameters along with the relationship between LBP and back muscle mass in Korean male and female fishery workers.
Methods
This retrospective study included a total of 146 subjects who underwent Fishermen’s health survey conducted between June 2018 and August 2020. LBP was evaluated through visual analogue scale (VAS) and Oswestry Disability Index (ODI). Sagittal spino-pelvic parameters were measured from whole spine standing X-rays. Back muscle cross-sectional areas were identified through lumbar spine magnetic resonance imaging and body composition was analyzed through bioelectrical impedance analysis.
Results
The study included 75 males and 71 females, with an average age of 58.33 years for males and 56.45 years for females. Female subjects exhibited higher VAS and ODI scores, larger pelvic tilt (PT) and trunk fat mass and smaller trunk muscle mass compared to males. In female, ODI positively correlated with sagittal vertical axis (SVA) and PT. No significant correlations were found between ODI scores and body composition in either sex. The high ODI group showed greater SVA, PT, and pelvic incidence-lumbar lordosis and higher trunk fat/muscle ratio. Psoas muscle mass, total and skeletal muscle mass and trunk muscle mass of that group were smaller than those of low ODI group.
Conclusion
Spino-pelvic parameters and back muscle mass were associated with ODI and there were differences between Korean male and female fishery workers.

Citations

Citations to this article as recorded by  
  • Lumbar paraspinal muscle quality and disability in older adults: insights from the SarcoSpine cohort
    Dong Hyun Kim, Yoon-Hee Choi, JooHee Lee, Sang Yoon Lee
    BMC Geriatrics.2026;[Epub]     CrossRef
  • Interrelationships of cervical spine sagittal alignment and whole spinopelvic alignment under implications of musculoskeletal health among independent elderly women in Taiwan: A cross-sectional study
    Tzai-Chiu Yu, Wen-Tien Wu, Ru-Ping Lee, Ing-Ho Chen, Jen-Hung Wang, Shu-Hui Wen, Kuang-Ting Yeh, Barry Kweh
    PLOS ONE.2024; 19(10): e0312082.     CrossRef
  • 8,582 View
  • 135 Download
  • 2 Web of Science
  • 2 Crossref

Review Articles

Dysphagia

Sarcopenic Dysphagia and Simplified Rehabilitation Nutrition Care Process: An Update
Shingo Kakehi, Eri Isono, Hidetaka Wakabayashi, Moeka Shioya, Junki Ninomiya, Yohei Aoyama, Ryoko Murai, Yuka Sato, Ryohei Takemura, Amami Mori, Kei Masumura, Bunta Suzuki
Ann Rehabil Med 2023;47(5):337-347.   Published online October 31, 2023
DOI: https://doi.org/10.5535/arm.23101
Sarcopenic dysphagia is characterized by weakness of swallowing-related muscles associated with whole-body sarcopenia. As the number of patients with sarcopenia increases with the aging of the world, the number of patients with sarcopenic dysphagia is also increasing. The prevalence of sarcopenic dysphagia is high in the institutionalized older people and in patients hospitalized for pneumonia with dysphagia in acute care hospitals. Prevention, early detection and intervention of sarcopenic dysphagia with rehabilitation nutrition are essential. The diagnosis of sarcopenic dysphagia is based on skeletal and swallowing muscle strength and muscle mass. A reliable and validated diagnostic algorithm for sarcopenic dysphagia is used. Sarcopenic dysphagia is associated with malnutrition, which leads to mortality and Activities of Daily Living (ADL) decline. The rehabilitation nutrition approach improves swallowing function, nutrition status, and ADL. A combination of aggressive nutrition therapy to improve nutrition status, dysphagia rehabilitation, physical therapy, and other interventions can be effective for sarcopenic dysphagia. The rehabilitation nutrition care process is used to assess and problem solve the patient’s pathology, sarcopenia, and nutrition status. The simplified rehabilitation nutrition care process consists of a nutrition cycle and a rehabilitation cycle, each with five steps: assessment, diagnosis, goal setting, intervention, and monitoring. Nutrition professionals and teams implement the nutrition cycle. Rehabilitation professionals and teams implement the rehabilitation cycle. Both cycles should be done simultaneously. The nutrition diagnosis of undernutrition, overnutrition/obesity, sarcopenia, and goal setting of rehabilitation and body weight are implemented collaboratively.

Citations

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  • Nutritional and physical pathways from feeding difficulty to sarcopenia in Alzheimer’s dementia
    Büşra Başar Gökcen, Elif Buse Canpolat, Ferenc Budán, Duygu Ağagündüz, Dávid Szép
    Frontiers in Nutrition.2026;[Epub]     CrossRef
  • Association of Coexisting Low Tongue Pressure and Sarcopenia with Pharyngeal Residue in Older Adults with Presbyphagia
    Hiroyasu Furuya, Takeshi Kikutani, Yuri Yokota, Maiko Ozeki, Fumiyo Tamura
    Dysphagia.2026;[Epub]     CrossRef
  • Negative association of dementia comorbidity with improvement of swallowing function and activities of daily living in patients with sarcopenic dysphagia: A multicenter retrospective cohort study
    Hiroshi Kishimoto, Hidetaka Wakabayashi, Shinta Nishioka, Ryo Momosaki
    Aging Medicine and Healthcare.2026; 17(1): 39.     CrossRef
  • Association of Sarcopenia at Admission with Physical Performance at Discharge in Older Patients with Subacute Stroke: A Prospective Cohort Study
    Yuto Kameyama, Ryota Ashizawa, Hiroya Honda, Koki Take, Kohei Yoshizawa, Ichiro Fujishima, Tomohisa Ohno, Kenjiro Kunieda, Takashi Shigematsu, Shintaro Iio, Yoshinobu Yoshimoto
    Progress in Rehabilitation Medicine.2026; 11: n/a.     CrossRef
  • Co-existence of Possible Sarcopenia and Dysphagia is Associated with Poor Functional Outcomes in Patients with Acute Stroke: A 1-Year Follow-up Study
    Yoichi Sato, Takafumi Abe, Yosuke Kimura, Shu Tanaka, Kazuki Okuda, Ayaki Shirahata, Kenta Yamamoto, Kazushige Ide, Masafumi Nozoe
    Annals of Geriatric Medicine and Research.2026; 30(2): 189.     CrossRef
  • Dual burden of sarcopenia and impaired oral status on activities of daily living, cognition and swallowing outcomes in post-stroke patients
    Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Takenori Hamada, Kouki Yoneda
    Archives of Gerontology and Geriatrics.2025; 129: 105648.     CrossRef
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    Gero Lueg, Maryam Pourhassan, Rainer Wirth
    Current Opinion in Clinical Nutrition & Metabolic Care.2025; 28(1): 14.     CrossRef
  • The rehabilitation nutrition oral care process: Implementing the triad of rehabilitation, nutrition, and oral management
    Hidetaka Wakabayashi
    Journal of General and Family Medicine.2025; 26(2): 114.     CrossRef
  • Association of antipsychotic drugs and tongue strength in patients with dysphagia: A cross-sectional study
    Hiroki Maki, Akio Shimizu, Hidetaka Wakabayashi, Shinta Nishioka, Ryo Momosaki
    Geriatric Nursing.2025; 64: 103334.     CrossRef
  • Prevalence of Dysphagia and Its Health Implications Among Elderly Residents in Long-Term Care Facilities in the Liguria Region (Italy): An Observational Cohort Study
    Elena Formisano, Enrico Di Cino, Elena Nicosia, Andrea Pasta, Gianfranco Paccione, Alessandro Antioco Sukkar, Livia Pisciotta, Samir Giuseppe Sukkar
    Nutrients.2025; 17(20): 3268.     CrossRef
  • Targeted Physical Rehabilitation for Physical Function Decline in Patients with Schizophrenia: A Narrative Review
    Ryuichi Tanioka, Kaito Onishi, Feni Betriana, Leah Bollos, Rick Yiu Cho Kwan, Anson Chui Yan Tang, Yueren Zhao, Yoshihiro Mifune, Kazushi Mifune, Tetsuya Tanioka
    Psychiatry International.2025; 6(4): 136.     CrossRef
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    Renata Marchewka, Tomasz Trzmiel, Katarzyna Hojan
    Brain Sciences.2024; 14(5): 430.     CrossRef
  • Malnutrition and cachexia may affect death but not functional improvement in patients with sarcopenic dysphagia
    Mai Yamanaka, Hidetaka Wakabayashi, Shinta Nishioka, Ryo Momosaki
    European Geriatric Medicine.2024; 15(3): 777.     CrossRef
  • Association between sarcopenia and urinary dysfunction in patients with dysphagia
    Shingo Kakehi, Hidetaka Wakabayashi, Eri Isono, Ryohei Takemura, Yuka Sato, Yukiko Otsuka, Takako Nagai, Shinta Nishioka, Ryo Momosaki
    Archives of Gerontology and Geriatrics.2024; 127: 105577.     CrossRef
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    Fumiko Furukawa, Kiyohito Kakita
    Cureus.2024;[Epub]     CrossRef
  • Nutritional care in older adults: are we doing everything? An expert opinion review
    Elisabet Sanchez-Garcia, Alfonso J. Cruz-Jentoft, Paula Ravasco, Merja Suominen, Prof Kaisu Pitkälä
    Current Medical Research and Opinion.2024; 40(9): 1563.     CrossRef
  • Age and sex differences in sarcopenic dysphagia: A secondary data analysis
    Hidetaka Wakabayashi, Shingo Kakehi, Ayano Nagano, Masako Kishima, Masataka Itoda, Shinta Nishioka, Ryo Momosaki
    Journal of General and Family Medicine.2024; 25(6): 343.     CrossRef
  • Triad of rehabilitation, nutrition support, and oral management improves activities of daily living and muscle health in hospitalized patients after stroke
    Yoshihiro Yoshimura, Sayuri Shimazu, Ai Shiraishi, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Yoshifumi Kido, Takahiro Bise, Aomi Kuzuhara, Takenori Hamada, Kouki Yoneda
    Clinical Nutrition ESPEN.2024; 63: 837.     CrossRef
  • The Prevalence and Prognosis of Cachexia in Patients with Non-Sarcopenic Dysphagia: A Retrospective Cohort Study
    Shingo Kakehi, Hidetaka Wakabayashi, Takako Nagai, Shinta Nishioka, Eri Isono, Yukiko Otsuka, Junki Ninomiya, Ryo Momosaki
    Nutrients.2024; 16(17): 2917.     CrossRef
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  • 348 Download
  • 19 Web of Science
  • 19 Crossref

Geriatric Rehabilitation

E-Health Interventions for Older Adults With Frailty: A Systematic Review
Hyeong-Wook Han, Si-Woon Park, Doo Young Kim, Bum-Suk Lee, Daham Kim, Namo Jeon, Yun-Jung Yang
Ann Rehabil Med 2023;47(5):348-357.   Published online October 27, 2023
DOI: https://doi.org/10.5535/arm.23090
Objective
To systematically review the efficacy of e-Health interventions on physical performance, activity and quality of life in older adults with sarcopenia or frailty.
Methods
A systematic review was conducted by searching the MEDLINE, Embase, Cochrane Library, CINHAL, Web of Science, and the Physiotherapy Evidence Database for experimental studies published in English from 1990 to 2021. E-Health studies investigating physical activity, physical performance, quality of life, and activity of daily living assessment in adults aged ≥65 years with sarcopenia or frailty were selected.
Results
Among the 3,164 identified articles screened, a total of 4 studies complied with the inclusion criteria. The studies were heterogeneous by participant characteristics, type of e-Health intervention, and outcome measurement. Age criteria for participant selection and sex distribution were different between studies. Each study used different criteria for frailty, and no study used sarcopenia as a selection criteria. E-Health interventions were various across studies. Two studies used frailty status as an outcome measure and showed conflicting results. Muscle strength was assessed in 2 studies, and meta-analysis showed statistically significant improvement after intervention (standardized mean difference, 0.51; 95% confidence interval, 0.07–0.94; p=0.80, I2=0%).
Conclusion
This systematic review found insufficient evidence to support the efficacy of e-Health interventions. Nevertheless, the studies included in this review showed positive effects of e-Health interventions on improving muscle strength, physical activity, and quality of life in older adults with frailty.

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    Surbhi Sood, Stuart K Roberts, David Scott, Shelley E Keating, Sze-Yen Tan, Jacob George, Nicole Kiss, Robin M Daly, David W Dunstan, Robin M Tucker, Elena S George
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    Ting Dai, Changsheng Guo, Lingli Gao, Jinyu Huang, Yan Chen, Yujie Zhang, Jing Gao, Xiaodong Feng
    Journal of Medical Internet Research.2026; 28: e88374.     CrossRef
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    Yaxin Chen, Lei Wu, Jing Li, Mengyuan Yang, Xin Qi, Mei Wang, Qi Li, Yanhong Wang
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    Genghua Huang, Samuel Ampadu Oteng, Silai Dong
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    Lina Sofía Morón-Duarte, Kelly Rocío Chacón-Acevedo, Wilson Daniel Ossa, Olga Victoria Gomez Gomez, Marco Stampini, Natalia Aranco, Nancy Yomayusa-González
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    Ruotong Peng, Zeng Cao, Shaolong Hu, Xinzhou Liu, Yongzhen Guo, Xiaoyang Li, Chi Zhang, Hui Feng
    Journal of Clinical Nursing.2025; 34(5): 1830.     CrossRef
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    Álvaro García-Bustillo, José Miguel Ramírez-Sanz, José Luis Garrido-Labrador, Alicia Olivares-Gil, Florita Valiñas-Sieiro, Marta Allende-Río, Josefa González-Santos, Jerónimo Javier González-Bernal, Maha Jahouh, Sara Calvo-Simal, Lucía Simón-Vicente, Nati
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    Mikel Izquierdo, Philipe de Souto Barreto, Hidenori Arai, Heike A. Bischoff-Ferrari, Eduardo L. Cadore, Matteo Cesari, Liang-Kung Chen, Paul M. Coen, Kerry S. Courneya, Gustavo Duque, Luigi Ferrucci, Roger A. Fielding, Antonio García-Hermoso, Luis Miguel
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    Tina Rishaug, Anne-Marie Aas, André Henriksen, Gunnar Hartvigsen, Kåre Inge Birkeland, Eirik Årsand, Ai Theng Cheong,
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    Kyuwan Lee
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    Yanyan Li, Meijun Liu, Jieru Yang, Qinqin Liu, Wendie Zhou, Jiaqi Yu, Xue Wang, Cuili Wang
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    Areej Al-Hamad, Yasin M. Yasin, Kateryna Metersky, Kristina M. Kokorelias, Lujain Yasin, Fatima Afzal
    Journal of Ageing and Longevity.2025; 5(3): 25.     CrossRef
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    Xinyu Wan, Xuehan Ma, Gengxin Yao, Yiran Xu, Yali Yang, Lishuang Zheng, Li Chen, Guichen Li
    Archives of Gerontology and Geriatrics.2025; 139: 106005.     CrossRef
  • Current and Future Challenges for Rehabilitation for Inflammatory Arthritis
    Rikke Helene Moe, Thea P. M. Vliet Vlieland
    Journal of Clinical Medicine.2024; 13(6): 1808.     CrossRef
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    Tsubasa Nakada, Kayo Kurotani, Takako Kozawa, Satoshi Seino, Shinichi Murota, Miki Eto, Junko Shimasawa, Yumiko Shimizu, Shinobu Tsurugano, Fuminori Katsukawa, Kazunori Sakamoto, Hironori Washizaki, Yo Ishigaki, Maki Sakamoto, Keiki Takadama, Keiji Yanai,
    Healthcare.2024; 12(23): 2365.     CrossRef
  • 13,985 View
  • 130 Download
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  • 20 Crossref

Geriatric Rehabilitation

Improved Muscle Mass and Function With Protein Supplementation in Older Adults With Sarcopenia: A Meta-Analysis
Hyo Eun Kwon, Nayeon Ko, Doyoung Yuk, Seo Won Choi, Seong-Eun Koh
Ann Rehabil Med 2023;47(5):358-366.   Published online October 23, 2023
DOI: https://doi.org/10.5535/arm.23076
Objective
To systematically review the effects of protein supplementation in older adults with sarcopenia.
Methods
A systematic literature search was conducted in PubMed, Cochrane Library, and Embase databases until May 2023. The inclusion criteria were as follows: (1) randomized controlled trials with a quantitative study design; (2) studies with a study group of older adults with sarcopenia; (3) studies comparing muscle mass, muscle strength, and performance of older adults with sarcopenia after protein supplementation; and (4) studies published up to May 2023.
Results
Six retrospective comparative studies, including 715 patients, met the inclusion criteria. The nutritional supplementation group exhibited significant improvement in appendicular skeletal muscle mass (standardized mean difference [SMD]=0.41; 95% confidence interval [CI], 0.24–0.58; p<0.001; I2=1%), while handgrip strength (SMD=0.37; 95% CI, -0.32–1.07; p=0.29; I2=94%) and Short Physical Performance Battery (SPPB) (SMD=0.35; 95% CI, -0.47–1.18; p=0.40; I2=94%) showed a tendency for improvement.
Conclusion
Nutritional supplementation with protein increased appendicular muscle mass in older adults with sarcopenia and improved handgrip strength and SPPB scores.

Citations

Citations to this article as recorded by  
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    Rizwan Qaisar
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    Sang Yoon Lee
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    Federico Bozzetti
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    Li‐Ning Peng, Ming‐Hsien Lin, Sung‐Hua Tseng, Ko‐Han Yen, Huei‐Fang Lee, Fei‐Yuan Hsiao, Liang‐Kung Chen
    Journal of Cachexia, Sarcopenia and Muscle.2024; 15(4): 1348.     CrossRef
  • SuperAgers and centenarians, dynamics of healthy ageing with cognitive resilience
    Md Ariful Islam, Ujala Sehar, Omme Fatema Sultana, Upasana Mukherjee, Malcolm Brownell, Sudhir Kshirsagar, P. Hemachandra Reddy
    Mechanisms of Ageing and Development.2024; 219: 111936.     CrossRef
  • Consumption of protein supplements/protein-fortified foods among young adults in Jeju
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    Age and Ageing.2024; 53(Supplement): ii13.     CrossRef
  • Nutrition resilience for healthy ageing
    Claire T McEvoy, Colin D McClure
    Age and Ageing.2024; 53(Supplement): ii1.     CrossRef
  • Study of whey protein on muscle mass and functional rehabilitation in postoperative total knee arthroplasty patients
    Mengshi Li, Qiongfang Shi, Xinle Che, Xingyan Du, Dongming Wang, Yufeng Song
    Journal of Back and Musculoskeletal Rehabilitation.2024; 37(5): 1381.     CrossRef
  • Functional status of the cardiovascular system in elderly patients with sarcopenia
    Iu. Samoilova, M. Matveeva, D. Podchinenova, Ya. Yakimova, L. Shuliko, V. Avkhimenko, D. Kudlay, E. Samoylov, E. Khoroshunova, A. Ragimov
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  • 30,581 View
  • 287 Download
  • 12 Web of Science
  • 15 Crossref

Original Articles

Geriatric Rehabilitation

Association of Diaphragm Thickness and Respiratory Muscle Strength With Indices of Sarcopenia
Yookyung Lee, Sunhan Son, Don-Kyu Kim, Myung Woo Park
Ann Rehabil Med 2023;47(4):307-314.   Published online August 28, 2023
DOI: https://doi.org/10.5535/arm.23081
Objective
To evaluate the relationship between respiratory muscle strength, diaphragm thickness (DT), and indices of sarcopenia.
Methods
This study included 45 healthy elderly volunteers (21 male and 24 female) aged 65 years or older. Sarcopenia indices, including hand grip strength (HGS) and body mass index-adjusted appendicular skeletal muscle (ASM/BMI), were measured using a hand grip dynamometer and bioimpedance analysis, respectively. Calf circumference (CC) and gait speed were also measured. Maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) were obtained using a spirometer, as a measure of respiratory muscle strength. DT was evaluated through ultrasonography. The association between indices of sarcopenia, respiratory muscle strength, and DT was evaluated using Spearman’s rank correlation test, and univariate and multiple regression analysis.
Results
ASM/BMI (r=0.609, p<0.01), CC (r=0.499, p<0.01), HGS (r=0.759, p<0.01), and gait speed (r=0.319, p<0.05) were significantly correlated with DT. In the univariate linear regression analysis, MIP was significantly associated with age (p=0.003), DT (p<0.001), HGS (p=0.002), CC (p=0.013), and gait speed (p=0.026). MEP was significantly associated with sex (p=0.001), BMI (p=0.033), ASM/BMI (p=0.003), DT (p<0.001), HGS (p<0.001), CC (p=0.001) and gait speed (p=0.004). In the multiple linear regression analysis, age (p=0.001), DT (p<0.001), and ASM/BMI (p=0.008) showed significant association with MIP. DT (p<0.001) and gait speed (p=0.050) were associated with MEP.
Conclusion
Our findings suggest that respiratory muscle strength is associated with DT and indices of sarcopenia. Further prospective studies with larger sample sizes are needed to confirm these findings.

Citations

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Orthosis & Prosthesis

Correlation of Femoral Muscle Volume Using Three-Dimensional Modeling and Locomotor Function After Unilateral Trans-femoral Amputation
Dong Hyuk Yun, Il-Young Jung, Chang Won Moon, Kang Hee Cho
Ann Rehabil Med 2022;46(6):303-311.   Published online December 31, 2022
DOI: https://doi.org/10.5535/arm.22110
Objective
To evaluate the relationship between femoral muscle volume (FMV) and physiological outcomes after trans-femoral amputations (TFAs) affecting overall locomotor function in patients.
Methods
Seven individuals who underwent TFA and had been using a prosthesis participated in this cross-sectional study. Gait and balance were assessed using clinical tests, such as 10-m walk test, 6-minute walk test, Berg Balance Scale, and automatic balance system. Respiratory gas analysis was performed to check oxygen consumption rate. Five participants were evaluated for bilateral FMV by MR imaging and FMV was reconstructed using three-dimentional remodeling.
Results
In five participants, significant differences were found between the non-involved and involved sides in femur length, total FMV, and functional muscle volume (all p<0.01) in all groups except for the hip adductor volume. The %mean difference between the non-involved and involved sides was 30% for femur length, 52.55% for hip flexor volume, 26.55% for hip adductor volume, 51.86% for hip extensor volume, and 60.21% for knee extensor volume. The hip flexor volume to hip extensor volume ratio in the involved limb and oxygen consumption rate during comfortable gait were negatively correlated (r=-0.96, p=0.04).
Conclusion
In individuals who underwent unilateral TFA, hip girdle muscle imbalance in the involved limbs may be associated with oxygen consumption rate while using a prosthesis.
  • 6,509 View
  • 73 Download

Brain disorders

Efficacy and Safety of Botulinum Toxin Type A (NABOTA) for Post-stroke Upper Extremity Spasticity: A Multicenter Phase IV Trial
Wonjae Hwang, Seong Min Kang, Sang Yoon Lee, Han Gil Seo, Yoon Ghil Park, Bum Sun Kwon, Kwang Jae Lee, Deog Young Kim, Hyoung Seop Kim, Shi-Uk Lee
Ann Rehabil Med 2022;46(4):163-171.   Published online August 31, 2022
DOI: https://doi.org/10.5535/arm.22061
Objective
To evaluate the efficacy and safety of Daewoong botulinum toxin type A (NABOTA) after its launch in South Korea.
Methods
This prospective, multicenter, open-label phase IV clinical trial included 222 patients with stroke. All patients visited the clinic at baseline and at weeks 4, 8, and 12 after injection of upto 360 units of NABOTA into the wrist, elbow, and finger flexor muscles at the first visit. The primary outcome was the change in Modified Ashworth Scale (MAS) score for the wrist flexor muscles between baseline and week 4. The secondary outcomes were the changes in MAS, Disability Assessment Scale (DAS), and Caregiver Burden Scale (CBS) scores between baseline and each visit, and the Global Assessment Scale (GAS) score at week 12.
Results
There was a statistically significant decrease in the MAS score for the wrist flexors between baseline and week 4 (-0.97±0.66, p<0.001). Compared with baseline, the MAS, DAS and CBS scores improved significantly during the study period. The GAS was rated as very good or good by 86.8% of physicians and by 60.0% of patients (or caregivers). The incidence of adverse events was 14.4%, which is smaller than that in a previous trial.
Conclusion
NABOTA showed considerable efficacy and safety in the management of upper limb spasticity in stroke patients.
  • 14,438 View
  • 176 Download

Pain & Musculoskeletal rehabilitation

Objective
To investigate the association of trunk fat and muscle composition, lumbar disc space narrowing, and low back pain in middle-aged farmers.
Methods
Fat and muscle areas were identified using standard Hounsfield unit ranges for adipose tissue and skeletal muscle with computed tomography images at the mid-L4 vertebral level. Trunk fat mass, muscle mass, and fat/muscle mass ratio were calculated. Low back pain was assessed using the Oswestry Disability Index (ODI). The L4/5-disc space and low back pain were also assessed.
Results
Male had a higher total trunk, back, psoas, and abdominal muscle mass, and visceral fat; female had a higher subcutaneous fat mass and fat/muscle ratio. Pearson correlation coefficients with ODI for waist circumference, total fat mass, visceral fat mass, and fat/muscle ratio were all significant in female; only the fat/muscle ratio was significant in male. Pearson correlation coefficients with L4/5-disc space narrowing grades for visceral fat mass, total, back, and psoas muscle mass, and fat/muscle ratio, were all significant in female; total and back muscle mass, and fat/muscle ratio in male.
Conclusion
There were significant relationships between: fat indicators with low back pain; trunk muscle mass with lumbar disc degeneration; and fat/muscle ratio with both lumbar disc degeneration and low back pain. The fat/muscle ratio may be a useful index for low back pain.

Citations

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    Ruchi Basista, Deepika Singla, Abhinav Jain
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    Hao Qi, Zenghui Zhao, Feiyu Zu, Chenxi Wang, Chenchen Wang, Zuzhuo Zhang, Xiaonan Tian, Dan Su, Zhaoxuan Wang, Rui Xue, Zhiyong Hou, Wei Chen, Di Zhang
    World Neurosurgery.2024; 189: e153.     CrossRef
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    Marian Pop, Marius Mărușteri
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    Myung Woo Park, Sang Jun Park, Sun Gun Chung
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    Journal of Clinical Medicine.2023; 12(19): 6156.     CrossRef
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    Seungsu Jeong, Gowun Kim, Hee-won Park, Sora Baek
    Annals of Rehabilitation Medicine.2023; 47(6): 468.     CrossRef
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Geriatric Rehabilitation

Efficacy of an Integrated Training Device in Improving Muscle Strength, Balance, and Cognitive Ability in Older Adults
Choong-Hee Roh, Da-Sol Kim, Gi-Wook Kim, Yu-Hui Won, Sung-Hee Park, Jeong-Hwan Seo, Myoung-Hwan Ko
Ann Rehabil Med 2021;45(4):314-324.   Published online August 30, 2021
DOI: https://doi.org/10.5535/arm.21072
Objective
To determine the effects of an integrated training device for strength and balance on extremity muscle strength, postural balance, and cognition in older adults using a combination with various rehabilitation training games, in which balance, strength, and cognitive training were configured in a single device.
Methods
This prospective study included 20 healthy participants aged 65–85 years. Participants trained for 30 minutes daily, 3 days weekly, for 6 weeks with an integrated training device for strength and balance (SBT-120; Man&Tel Inc., Gumi, Korea). Main outcomes were measured using the Korean Mini-Mental State Examination (K-MMSE), Korean version of the Montreal Cognitive Assessment (K-MoCA), Timed Up and Go Test (TUG), Functional Reach Test (FRT), Berg Balance Scale (BBS), and Manual Muscle Test. Measurements were taken at three time points: T0 (pretreatment), T1 (immediately after treatment), and T2 (4 weeks after treatment).
Results
All 20 patients completed the training, and TUG, FRT, and BBS scores significantly improved at T1 and T2 compared to T0. Mean TUG scores decreased by 0.99±2.00 at T1 and 1.05±1.55 at T2 compared to T0. Mean FRT scores increased by 6.13±4.26 at T1 and 6.75±4.79 at T2 compared to T0. BBS scores increased by 0.60±0.94 at T1 and 0.45±1.15 at T2 compared to T0. Moreover, muscle strength and cognition (K-MMSE and K-MoCA scores) increased after training.
Conclusion
Our findings suggest that an integrated training device for strength and balance can be a safe and useful tool for older adults.

Citations

Citations to this article as recorded by  
  • Effects of Comprehensive Activity Training Program on Cognitive and Physical Abilities Among Older Adults with Mild Cognitive Impairment
    Chutima Thongwachira, Teeranut Harnirattisai, Diana Morris
    The Journal of Behavioral Science.2025; 20(1): 30.     CrossRef
  • 9,736 View
  • 130 Download
  • 1 Web of Science
  • 1 Crossref

Review Article

Cardiopulmonary rehabilitation

Effectiveness of Inspiratory Muscle Training on Respiratory Muscle Strength in Patients Undergoing Cardiac Surgeries: A Systematic Review With Meta-Analysis
Fiona Verdine Dsouza, Sampath Kumar Amaravadi, Stephen Rajan Samuel, Harish Raghavan, Nagaraja Ravishankar
Ann Rehabil Med 2021;45(4):264-273.   Published online August 30, 2021
DOI: https://doi.org/10.5535/arm.21027
To determine the effect of inspiratory muscle training (IMT) on pulmonary function, respiratory muscle strength (RMS), and functional capacity in patients undergoing cardiac surgery. The PubMed, PEDro, CINAHL, Web of Science, CENTRAL, and EMBASE databases were searched from inception to June 2020. Randomized controlled trials (RCTs) that evaluated patients who underwent cardiac surgery were included in this review. Meta-analysis performed using a random-effects model showed that the mean difference in forced vital capacity, forced expiratory volume in 1 second, 6-minute walk distance, and RMS was 3.47% (95% confidence interval [CI], 0.57 to 6.36), 5.80% (95% CI, 2.03 to 9.56), 78.05 m (95% CI, 60.92 to 95.18), and 4.8 cmH2O (95% CI, -4.00 to 13.4), respectively. There is strong evidence that IMT improves inspiratory muscle strength, pulmonary function, and functional capacity, and reduces the length of hospital stay in patients undergoing cardiac surgery.

Citations

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  • Effect of Breathing Exercises to Prevent Pulmonary Complications in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery: A Pilot Study
    Chao Li, Cuiyuan Huo, Hongli Li, Ruitian Ding, Ping Zhang
    Journal of Cardiothoracic and Vascular Anesthesia.2026;[Epub]     CrossRef
  • Nursing Care Across the Clinical Continuum of TAVI: A Systematic Review of Multidisciplinary Roles
    Anna Jendrzejczak, Jadwiga Klukow, Joanna Czerwik-Marcinkowska, Wojciech Styk, Szymon Zmorzynski
    Journal of Clinical Medicine.2025; 14(13): 4535.     CrossRef
  • The Effects of Pursed Lip Breathing Exercises on Patients' Post‐Bronchoscopy Recovery Parameters: A Nurse‐Led Quasi‐Experimental Study
    Rasha Abdulhalim Alqadi, Azza Ibrahim Abdelkader Habiba, Hanaa Hamad Mohamed El Sayed Akl, Engy AbdelRhman Khamis, Daniel Joseph E. Berdida
    Nursing & Health Sciences.2025;[Epub]     CrossRef
  • Inspiratory Muscle Training Improved Cardiorespiratory Performance in Patients Undergoing Open Heart Surgery: A Randomized Controlled Trial
    Chitima Kulchanarat, Suphannee Choeirod, Supattra Thadatheerapat, Dusarkorn Piathip, Opas Satdhabudha, Kornanong Yuenyongchaiwat
    Advances in Respiratory Medicine.2025; 93(3): 10.     CrossRef
  • Benefits of Cardiac Rehabilitation: Mechanisms to Restore Function and Clinical Impact
    Abdulla A. Damluji, Corey R. Tomczak, Stephanie Hiser, Deirdre E. O’Neill, Parag Goyal, Quinn R. Pack, Stephen J. Foulkes, Todd M. Brown, Mark J. Haykowsky, Dale M. Needham, Daniel E. Forman
    Circulation Research.2025; 137(2): 255.     CrossRef
  • Effectiveness of Active Cycle of Breathing Technique in Improving Physiological and Functional Outcomes Following Coronary Artery Bypass Graft Surgery: A Narrative Review
    Arnengsih Nazir
    Journal of Multidisciplinary Healthcare.2025; Volume 18: 5431.     CrossRef
  • Effects of Respiratory Muscle Training in Patients with Cardiomyopathy: Systematic Review
    Hanifa Suleman, Zohaib Shahid, Muhammad Naveed Babur, Abdul Wadood, Khizar Abid, Muhammad Ali Khan, Asna Waseem
    The Healer Journal of Physiotherapy and Rehabilitation Sciences.2025; 5(1): 233.     CrossRef
  • Respiratory therapy with positive expiratory pressure in patients after left ventricle geometric reconstruction
    Maksim L. Mamalyga, Mikhail M. Alshibaya, Mark A. Zatenko, Sergey A. Danilov, Gela G. Getsadze, Sergey L. Babak
    RUDN Journal of Medicine.2025; 29(2): 162.     CrossRef
  • Respiratory Muscle Training Combinations in Amateur Runners: A Randomized Trial of Pulmonary Function, Respiratory Muscle Strength, and Exercise Capacity
    Eunho Lee, Jinseop Kim
    Bioengineering.2025; 13(1): 11.     CrossRef
  • Can resistance prehabilitation training bring additional benefits in valvular cardiac surgery? protocol for a randomized controlled trial
    Jorge Montero-Cámara, Francisco José Ferrer-Sargues, María José Segrera Rovira, Adrián Sarria Cabello, David Cuesta Peredo, Juan Antonio Margarit Calabuig, Noemí Valtueña-Gimeno, María Luz Sánchez-Sánchez, Robert Jeenchen Chen
    PLOS ONE.2024; 19(5): e0303163.     CrossRef
  • Effectiveness of improving coordination abilities after cardiac surgery: a review
    Natalya V. Arkhipova, Svetlana A. Pomeshkina, Evgeniy V. Bykov
    Bulletin of Rehabilitation Medicine.2024; 23(3): 52.     CrossRef
  • Inspiratory Muscle Training in Phase 1 and 2 Postoperative Cardiac Rehabilitation Following Coronary Artery Bypass Graft Surgery: Systematic Review With Meta-Analysis
    Clênia Oliveira Araújo, Carla Cristina Araújo Alves, Francisco R A dos Santos, Lawrence P Cahalin, Graziella França Bernardelli Cipriano, Gerson Cipriano
    Physical Therapy.2024;[Epub]     CrossRef
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    Linqi Fang, Anqi Cheng, Zhaohua Zhu, Mengming Shao, Guoai Wang
    Journal of Cardiopulmonary Rehabilitation and Prevention.2024; 44(5): 324.     CrossRef
  • Effects of preoperative respiratory muscle training for improvement of postoperative health related quality of life in mitral valve replacement patients
    Umama Umar, Ahad Hussain, Komal Tariq
    Physiotherapy Research International.2024;[Epub]     CrossRef
  • Benefits from Implementing Low- to High-Intensity Inspiratory Muscle Training in Patients Undergoing Cardiac Surgery: A Systematic Review
    Aphrodite Evangelodimou, Irini Patsaki, Alexandros Andrikopoulos, Foteini Chatzivasiloglou, Stavros Dimopoulos
    Journal of Cardiovascular Development and Disease.2024; 11(12): 380.     CrossRef
  • The impact of threshold-loaded inspiratory muscle training and respiratory biofeedback on preserving inspiratory muscle strength and vital capacity after CABG: a randomized clinical trial
    Bahareh Mehregan-Far
    American Journal of Cardiovascular Disease.2024; 14(6): 375.     CrossRef
  • Distinguishing science from pseudoscience in commercial respiratory interventions: an evidence-based guide for health and exercise professionals
    Camilla R. Illidi, Lee M. Romer, Michael A. Johnson, Neil C. Williams, Harry B. Rossiter, Richard Casaburi, Nicholas B. Tiller
    European Journal of Applied Physiology.2023; 123(8): 1599.     CrossRef
  • Inspiratory Muscle and Functional Performance of Patients Entering Cardiac Rehabilitation after Cardiac Valve Replacement
    Sabine Gempel, Meryl Cohen, Eryn Milian, Melany Vidret, Andrew Smith, Ian Jones, Yessenia Orozco, Neva Kirk-Sanchez, Lawrence P. Cahalin
    Journal of Cardiovascular Development and Disease.2023; 10(4): 142.     CrossRef
  • Comparison of Effects of Liuzijue Exercise and Conventional Respiratory Training on Patients after Cardiac Surgery: A Randomized Controlled Trial
    Qiao-li Zhang, Min Ge, Cheng Chen, Fu-dong Fan, Yan Jin, Ning Zhang, Lei Wang
    Chinese Journal of Integrative Medicine.2023; 29(7): 579.     CrossRef
  • Inspiratory muscle training to reduce risk of pulmonary complications after coronary artery bypass grafting: a systematic review and meta-analysis
    Yuping Xiang, Qin Zhao, Tinahui Luo, Ling Zeng
    Frontiers in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • Impact of cardiac rehabilitation on pre- and post-operative transcatheter aortic valve replacement prognoses
    Jieru Zou, Jie Yuan, Jingjin Liu, Qingshan Geng
    Frontiers in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • The Effects of Inspiratory Muscle Training (IMT) on Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery: A Systematic Review and Meta-Analysis
    Sisi Zhang, Bo Li, Xiaoping Meng, Houjuan Zuo, Dayi Hu
    Reviews in Cardiovascular Medicine.2023;[Epub]     CrossRef
  • Resistance exercise for cardiac rehabilitation
    Danielle L. Kirkman, Duck-chul Lee, Salvatore Carbone
    Progress in Cardiovascular Diseases.2022; 70: 66.     CrossRef
  • Respiratory Muscle Strength in Patients with Coronary Heart Disease and Different Musculoskeletal Disorders
    E. D. Bazdyrev, N. A. Terentyeva, N. A. Galimova, K. E. Krivoshapova, O. L. Barbarash
    Rational Pharmacotherapy in Cardiology.2022; 18(4): 393.     CrossRef
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  • 24 Crossref

Original Article

Pain & Musculoskeletal rehabilitation

Objective
To investigate differences in the relative sizes of the ankle-stabilizing muscles in individuals with versus without flexible flat feet and to determine predictors of symptom severity.
Methods
This cross-sectional study included 30 patients with symptomatic flexible flat feet and 24 normal controls. The following were evaluated: foot posture index, resting calcaneal stance position angle, radiographic findings (calcaneal pitch, Meary’s angle, talocalcaneal angle, talonavicular coverage angle [TNCA]), foot function index (FFI), and cross-sectional areas (CSA) of the tibialis anterior (TA), tibialis posterior (TP), and peroneus longus (PL) upon ultrasonographic examination. To address morphometric differences among participants, individual muscle measurements were normalized to proportions of total muscle CSA. Between-group differences were evaluated with independent t-tests. Correlations between muscle ratios, radiographic parameters, and FFI scores were investigated. Logistic regression analysis was performed to determine which parameters predicted severe symptoms.
Results
The relative size of the TP was significantly greater and those of the TA and PL were significantly smaller in patients with flat feet than in normal controls. Correlations were found among relative muscle CSA ratios, radiographic parameters, and FFI score. Linear regression analysis confirmed that the TNCA and the relative CSA of the PL were independent predictors of symptom severity.
Conclusion
This study found significant differences in the relative CSAs of the ankle muscles in patients with flexible flat feet versus individuals without flat feet; these differences were significantly correlated with anatomic abnormalities. Symptoms were more severe in patients with relatively greater forefoot abduction and relatively smaller PL.

Citations

Citations to this article as recorded by  
  • Plantar pressures in symptomatic and asymptomatic flexible flatfeet: how do they differ?
    Victoria Blackwood, Kelly A. Jeans, Rusty L. Hartman, Kirsten Tulchin-Francis, Jacob R. Zide, Anthony I. Riccio
    Journal of Pediatric Orthopaedics B.2026; 35(3): 250.     CrossRef
  • Does severity of the flatfoot deformity affect pain and mobility in adolescents with symptomatic flatfoot
    Matthew William, Daniel E. Pereira, Beltran Torres-Izquierdo, Claire Schaibley, Pooya Hosseinzadeh
    Journal of Pediatric Orthopaedics B.2025; 34(2): 189.     CrossRef
  • 정상발 및 평발 집단의 발목관절 토크 및 만성발목불안정증(CAI)의 특성 차이
    석경 안, 상근 조, 승재 김
    The Korean Journal of Physical Education.2024; 63(5): 339.     CrossRef
  • Relation of Flatfoot Severity with Flexibility and Isometric Strength of the Foot and Trunk Extensors in Children
    Min Hwan Kim, Sangha Cha, Jae Eun Choi, Minsoo Jeon, Ja Young Choi, Shin-Seung Yang
    Children.2022; 10(1): 19.     CrossRef
  • Effect of Foot Orthoses in Children With Symptomatic Flexible Flatfoot Based on Ultrasonography of the Ankle Invertor and Evertor Muscles
    Dong Joon Cho, So Young Ahn, Soo-Kyung Bok
    Annals of Rehabilitation Medicine.2021; 45(6): 459.     CrossRef
  • Biomechanical Evidence From Ultrasonography Supports Rigid Foot Orthoses in Children With Flatfoot
    Joon-Ho Shin
    Annals of Rehabilitation Medicine.2021; 45(6): 411.     CrossRef
  • 9,318 View
  • 191 Download
  • 7 Web of Science
  • 6 Crossref

Case Report

Brain disorders

Upper Extremity Deep Vein Thrombosis After Botulinum Toxin Injection: A Case Report
Nana Lim, Geun Su Lee, Ki Hong Won, Jin Sun Kang, Sung Hoon Lee, Eun Young Kang, Hyun Kyung Lee, Youn Kyung Cho
Ann Rehabil Med 2021;45(2):160-164.   Published online April 14, 2021
DOI: https://doi.org/10.5535/arm.20118
Botulinum toxin (BoNT) injection is widely used to improve spasticity. However, after the treatment, the patient may experience pain, inflammation, swelling and redness at the injection site. In this case, we addressed deep vein thrombosis (DVT) after BoNT treatment of the upper limb. A male aged 37 years had spasticity and dystonia in his left upper extremity. BoNT-A 100 U was injected into the left biceps brachii and an equal amount into the brachialis to relieve spasticity. After three days, he developed redness and painful swelling in the left upper arm and the next day, through the upper extremity computed tomography venography, DVT was identified in the left cephalic vein. The thrombus resolved after the anticoagulation therapy with rivaroxaban (Xarelto). We hypothesized the role of mainly three mechanisms in the development of DVT in this case: repetitive strenuous activity, relative stasis due to reduced muscle tone, and possible direct mechanical damage to the vessel wall.
  • 9,478 View
  • 235 Download

Original Articles

Electrodiagnosis

Which Approach Is Most Optimal for Needle Electromyographic Examination of the Biceps Femoris Short Head: Medial or Lateral?
Jong Heon Park, Im Joo Rhyu, Ha Kyoung Lim, Jae Hyun Cha, Gi Jun Shin, Hye Chang Rhim, Dong Hwee Kim
Ann Rehabil Med 2021;45(1):42-48.   Published online February 9, 2021
DOI: https://doi.org/10.5535/arm.20092
Objective
To investigate the anatomical characteristics of the biceps femoris short head (BS) and determine the optimal needle placement for BS examination.
Methods
Twenty-one lower limbs were dissected. The distances from the medial and lateral margins of the biceps femoris long head (BL) tendon to the common fibular nerve (CFN) (M_CFN_VD and L_CFN_VD, respectively) and the distance from the lateral margin of the BL tendon to the lateral margin of the BS (L_BS_HD) were measured 5 cm proximal to the tip of the fibular head (P1), four fingerbreadths proximal to the tip of the fibular head (P2), and at the upper apex of the popliteal fossa (P3).
Results
The BS was located lateral to the BL tendon. The CFN was located along the medial margin of the BL tendon. The median values were 2.0 (P1), 3.0 (P2), and 0 mm (P3) for M_CFN_VD; and 17.4 (P1), 20.2 (P2), and 21.8 mm (P3) for L_CFN_VD; and 8.1 (P1), 8.8 (P2), and 13.0 mm (P3) for L_BS_VD.
Conclusion
The lateral approach to the BL tendon was safer than the medial approach for examining the BS. Amore proximal insertion site around the upper apex of the popliteal fossa was more accurate than the distal insertion site. In this study, we propose a safer and more accurate approach for electromyography of the BS.

Citations

Citations to this article as recorded by  
  • Ultrasound Depiction of the Optimal Window for Needle Placement for Electromyography of the Short Head of the Biceps Femoris
    Reece M. Hass, Cecilia V. Mitchell, James B. Meiling, William J. Litchy, Andrea J. Boon
    Muscle & Nerve.2026; 73(4): 630.     CrossRef
  • Muscle dynamics analysis by clustered categories during jogging in patients with anterior cruciate ligament deficiency
    Haoran Li, Hongshi Huang, Si Zhang, Shuang Ren, Qiguo Rong
    BMC Musculoskeletal Disorders.2023;[Epub]     CrossRef
  • 7,534 View
  • 175 Download
  • 2 Web of Science
  • 2 Crossref
Knee Extensor Strength Measurement in Patients With Limited Physical Activity Using a Supine Dynamometer Anchoring Frame
Min-Yong Lee, Kwan-Sik Sung, Hyungsuk Ham, You Gyoung Yi, Hyung-Ik Shin
Ann Rehabil Med 2020;44(6):502-509.   Published online December 31, 2020
DOI: https://doi.org/10.5535/arm.20056
Objective
To investigate the reliability of knee extensor strength measurements using a supine hand-held dynamometer (HHD) anchoring frame in patients with limited physical activity. Although an HHD is suitable for bedside use, its inter-rater reliability is low because measurements can be influenced by tester strength.
Methods
Maximal knee extensor isometric strength was measured using an HHD anchored to the supine frame. Three trials of three maximal contractions were assessed by two raters.
Results
A total of 33 inpatients who were non-ambulatory due to acute illness participated in the study. The intraclass correlation coefficients were 0.974 (inter-rater) and 0.959 (intra-rater). The minimal detectable changes in intra- and inter-observer measurements were 29.46 N (24.10%) and 36.73 N (29.26%), respectively. The limits of agreement ranged from -19.79% to 24.81% for intra-rater agreement and from -21.45% to 37.07% for inter-rater agreement.
Conclusion
The portable dynamometer anchoring system can measure the isometric strength of the knee extensor reliably in the supine position, and could be used for measurements in patients who have difficulty visiting the laboratory and maintaining a seated posture.

Citations

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  • Mim-pong: a serious game for assessment and treatment of the lower limb in hemiparetic stroke patients
    Fernando L. F. Eichinger, Fabrício Noveletto, Susana C. Domenech, Thierry Moulin, Yoshimasa Sagawa, Antonio Vinicius Soares
    Archives of Physiotherapy.2025; : 59.     CrossRef
  • Development and performance verification of an isometric dynamometer for lower extremity
    Yihua Wang, Yining Sun, Lisheng Gao, Zuchang Ma, Xianjun Yang
    Scientific Reports.2025;[Epub]     CrossRef
  • Toe Grip Strength Is Associated with Improving Gait Function in Patients with Subacute Stroke
    Jin-Whan Ryu, In-Su Hwang, Sol Jin, Soo-A Kim, Min-Su Kim
    Brain Sciences.2024; 14(3): 215.     CrossRef
  • Development and validation of a portable articulated dynamometry system to assess knee extensor muscle strength
    Youho Myong, Sungwoo Park, Minwoo Cho, Seung Yeon Cho, Woo Hyung Lee, Byung-Mo Oh, Sungwan Kim
    Scientific Reports.2023;[Epub]     CrossRef
  • 8,315 View
  • 136 Download
  • 5 Web of Science
  • 4 Crossref
Ultrasound Imaging of the Trunk Muscles in Acute Stroke Patients and Relations With Balance Scales
Yunho Kim, Jeeyoung Kim, Heesung Nam, Hyun Dong Kim, Mi Ja Eom, Sang Hoon Jung, Nami Han
Ann Rehabil Med 2020;44(4):273-283.   Published online July 28, 2020
DOI: https://doi.org/10.5535/arm.19125
Objective
To examine the correlation between ultrasonographic trunk muscle parameters and balance scales in mild acute stroke patients.
Methods
A total of 55 stroke patients with hemiparesis and motor power grade ≥4 in the manual motor test were included. The Scale for the Assessment and Rating of Ataxia (SARA), Berg Balance Scale (BBS), Timed Up and Go Test (TUG), and Trunk Control Test (TCT) were used to evaluate patient balance function. Ultrasonographic parameters were measured on both non-paretic and paretic sides of the rectus abdominis, external oblique, internal oblique, transversus abdominis, and erector spinae muscles. Resting thickness and contraction thickness were measured in all muscles, and contractility and contractility ratio were calculated based on measured thicknesses. The differences between paretic and non-paretic muscle parameters, and the correlation between ultrasonographic parameters and balance scales were analyzed. Stroke patients were divided into two groups according to their fall risk. Ultrasonographic measurements between the two groups were compared.
Results
All muscles’ contraction thickness and contractility were significantly different between paretic and non-paretic sides (p<0.001). Contractility ratios of all trunk muscles showed a significant correlation with SARA, BBS, TUG, and TCT (p<0.05). Contractility ratios of all muscles were significantly different between high- and low-risk fall groups (p<0.05).
Conclusion
The contractility ratio in stroke patients reflects their balance disturbance and fall risk and it may serve as a new parameter for ultrasound imaging of trunk muscles.

Citations

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  • Respiratory muscle weakness after stroke: An exploratory mediation analysis of associated factors
    Natalia Domínguez-Sanz, Robinson Ramírez-Vélez
    Respiratory Medicine.2026; 257: 108842.     CrossRef
  • Ultrasonographic Evaluation of Respiratory Muscles in Stroke Patients and Its Correlation With Pulmonary Function Tests
    Yunus Emre Doğan, Kadriye Öneş, Burak Kütük
    Acupuncture & Electro-Therapeutics Research: International Journal of Integrated Medicine.2026;[Epub]     CrossRef
  • Immediate effects of trunk Kinesio Taping® on functional parameters in the acute stage of patients with mild stroke: A randomized controlled trial
    Asalet Aybüke Güp, Banu Bayar
    Physiotherapy Theory and Practice.2024; 40(7): 1447.     CrossRef
  • Investigation of the reliability and validity of the Turkish version of the Sitting Balance Scale in individuals with stroke
    Kübra Çapraz, Saniye Aydoğan Arslan, Teoman Çolak
    Acta Neurologica Belgica.2024; 124(1): 81.     CrossRef
  • The investigation of ultrasound to assess lateral abdominal wall activation with different types of core exercises
    Nan Hu, Fengshan Huang, Rui Yu, Neil Chen Yi Lun MacAlevey, Yi Zeng, Ping Miao
    BMC Sports Science, Medicine and Rehabilitation.2024;[Epub]     CrossRef
  • Respiratory muscle ultrasonography evaluation and its clinical application in stroke patients: A review
    Xiaoman Liu, Ying Yang, Jie Jia
    Frontiers in Neuroscience.2023;[Epub]     CrossRef
  • BOBATH vs. TASK-ORIENTED TRAINING AFTER STROKE: An assessor-blind randomized controlled trial
    Gülşah Sütçü, Levent Özçakar, Ali İmran Yalçın, Muhammed Kılınç
    Brain Injury.2023; 37(7): 581.     CrossRef
  • Association between trunk core muscle thickness and functional ability in subacute hemiplegic stroke patients: an exploratory cross-sectional study
    Jee Hyun Suh, Eun Chae Lee, Joo Sup Kim, Seo Yeon Yoon
    Topics in Stroke Rehabilitation.2022; 29(3): 163.     CrossRef
  • Ultrasonography of abdominal muscles: Differential diagnosis of late-onset Pompe disease and myotonic dystrophy type 1
    Pei-Chen Hsieh, Chun-Wei Chang, Long-Sun Ro, Chin-Chang Huang, Jia-En Chi, Hung-Chou Kuo
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Investigation of Structural Changes in Rectus Abdominis Muscle According to Curl-Up Angle Using Ultrasound with an Extended Field of View
    Chansol Park, Hwi-Young Cho, Chang-Ki Kang
    International Journal of Environmental Research and Public Health.2022; 19(21): 14525.     CrossRef
  • Trunk Muscle Activation Patterns During Standing Turns in Patients With Stroke: An Electromyographic Analysis
    I-Hsuan Chen, Pei-Jung Liang, Valeria Jia-Yi Chiu, Shu-Chun Lee
    Frontiers in Neurology.2021;[Epub]     CrossRef
  • 11,509 View
  • 190 Download
  • 14 Web of Science
  • 11 Crossref
Efficacy and Safety of Abdominal Trunk Muscle Strengthening Using an Innovative Device in Elderly Patients With Chronic Low Back Pain: A Pilot Study
Satoshi Kato, Satoru Demura, Yuki Kurokawa, Naoki Takahashi, Kazuya Shinmura, Noriaki Yokogawa, Noritaka Yonezawa, Takaki Shimizu, Ryo Kitagawa, Hiroyuki Tsuchiya
Ann Rehabil Med 2020;44(3):246-255.   Published online May 29, 2020
DOI: https://doi.org/10.5535/arm.19100
Objective
To examine the efficacy and safety of an innovative, device-driven abdominal trunk muscle strengthening program, with the ability to measure muscle strength, to treat chronic low back pain (LBP) in elderly participants.
Methods
Seven women with non-specific chronic LBP, lasting at least 3 months, were enrolled and treated with the prescribed exercise regimen. Patients participated in a 12-week device-driven exercise program which included abdominal trunk muscle strengthening and 4 types of stretches for the trunk and lower extremities. Primary outcomes were adverse events associated with the exercise program, improvement in abdominal trunk muscle strength, as measured by the device, and improvement in the numerical rating scale (NRS) scores of LBP with the exercise. Secondary outcomes were improvement in the Roland-Morris Disability Questionnaire (RDQ) score and the results of the locomotive syndrome risk test, including the stand-up and two-step tests.
Results
There were no reports of increased back pain or new-onset abdominal pain or discomfort during or after the device-driven exercise program. The mean abdominal trunk muscle strength, NRS, RDQ scores, and the stand-up and two-step test scores were significantly improved at the end of the trial compared to baseline.
Conclusion
No participants experienced adverse events during the 12-week strengthening program, which involved the use of our device and stretching, indicating the program was safe. Further, the program significantly improved various measures of LBP and physical function in elderly participants.

Citations

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    Ahmad Zahid Rao, Saba Shahid Siddique, Muhammad Danish Mujib, Muhammad Abul Hasan, Ahmad O. Alokaily, Tayyaba Tahira
    IEEE Access.2024; 12: 41676.     CrossRef
  • Relationship between Respiratory Function and the Strength of the Abdominal Trunk Muscles Including the Diaphragm in Middle-Aged and Older Adult Patients
    Yuki Kurokawa, Satoshi Kato, Noriaki Yokogawa, Takaki Shimizu, Hidenori Matsubara, Tamon Kabata, Satoru Demura
    Journal of Functional Morphology and Kinesiology.2024; 9(4): 175.     CrossRef
  • Research hotspots and frontiers in non-specific low back pain: a bibliometric analysis
    Qiangjian Mao, Yuqing Wang, Shiqi Xu, Desheng Wu, Guomin Huang, Ziru Li, Lin Jiao, Zhenhai Chi
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Validation and comparison of trunk muscle activities in male participants during exercise using an innovative device and abdominal bracing maneuvers
    Yuki Kurokawa, Satoshi Kato, Satoru Demura, Kazuya Shinmura, Noriaki Yokogawa, Noritaka Yonezawa, Takaki Shimizu, Ryo Kitagawa, Hiroichi Miaki, Hiroyuki Tsuchiya
    Journal of Back and Musculoskeletal Rehabilitation.2022; 35(3): 589.     CrossRef
  • Evaluation of locomotive syndrome in patients receiving surgical treatment for degenerative musculoskeletal diseases: A multicentre prospective study using the new criteria
    Satoshi Kato, Satoru Demura, Tamon Kabata, Hidenori Matsubara, Yuki Kurokawa, Yoshitomo Kajino, Yoshiyuki Okamoto, Kazunari Kuroda, Hiroaki Kimura, Kazuya Shinmura, Noriaki Yokogawa, Takaki Shimizu, Kentaro Igarashi, Daisuke Inoue, Hiroyuki Tsuchiya
    Modern Rheumatology.2022; 32(4): 822.     CrossRef
  • Associations between Abdominal Trunk Muscle Weakness and Future Osteoporotic Vertebral Fracture in Middle-Aged and Older Adult Women: A Three-Year Prospective Longitudinal Cohort Study
    Satoshi Kato, Satoru Demura, Kazuya Shinmura, Noriaki Yokogawa, Yuki Kurokawa, Ryohei Annen, Motoya Kobayashi, Yohei Yamada, Satoshi Nagatani, Hidenori Matsubara, Tamon Kabata, Hiroyuki Tsuchiya
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Suggested Assessments for Sarcopenia in Patients With Stroke Who Can Walk Independently
Ho Joong Jung, Yong Min Lee, Minsun Kim, Kyeong Eun Uhm, Jongmin Lee
Ann Rehabil Med 2020;44(1):20-37.   Published online February 29, 2020
DOI: https://doi.org/10.5535/arm.2020.44.1.20
Objective
To investigate variables for assessment of stroke-related sarcopenia that are alternative options to the current assessment for sarcopenia, which focuses on age-related sarcopenia and also has limitations in addressing sarcopenia due to weakness resulting from stroke.
Methods
Forty patients (17 men, 23 women; mean age, 66.9±15.4 years) with first-ever stroke who can walk independently were included. Muscle mass was determined by measuring ultrasonographic muscle thickness of vastus intermedius, rectus femoris, tibialis anterior, medial gastrocnemius, and biceps brachii muscles in addition to using the skeletal muscle index (SMI) with bioelectrical impedance analysis. Muscle strength was assessed with the Medical Research Council (MRC) sum score as well as handgrip (HG) strength. Physical performance was measured by the Berg Balance Scale (BBS) along with 4-meter gait speed (4MGS). Correlations between each assessment in the three categories were analyzed and adjusted by stroke severity, comorbidity, and nutritional status.
Results
For muscle mass, SMI showed the highest correlation with the tibialis anterior muscle (r=0.783, p<0.001) among the other muscles. Regarding muscle strength, the MRC sum score correlated with the HG (r=0.660, p<0.001). For physical performance, the BBS correlated with the 4MGS (r=0.834, p<0.001). The same result was obtained after adjusting for factors of stroke severity, comorbidity, and nutritional status.
Conclusion
These results suggest that ultrasonographic muscle thickness of the tibialis anterior, the MRC sum score, and BBS might be alternatives to SMI, HG, and usual gait speed for sarcopenia in stroke patients.

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    International Journal of Environmental Research and Public Health.2020; 17(19): 7064.     CrossRef
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Effects of Strengthening and Stretching Exercises on the Temporospatial Gait Parameters in Patients With Plantar Fasciitis: A Randomized Controlled Trial
Suthasinee Thong-On, Sunee Bovonsunthonchai, Roongtiwa Vachalathiti, Warinda Intiravoranont, Sarawut Suwannarat, Richard Smith
Ann Rehabil Med 2019;43(6):662-676.   Published online December 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.6.662
Objective
To investigate the effects of physical therapy interventions using strengthening and stretching exercise programs on pain and temporospatial gait parameters in patients with plantar fasciitis (PF).
Methods
Eighty-four patients with PF participated in the study and were randomly assigned to the strengthening or stretching exercise groups. All patients received 8 physical therapy interventions two times per week in the first 4 weeks and performed daily strengthening or stretching exercises three times per day. After 4 weeks, they continued the assigned exercise programs every day for 8 weeks. Pain visual analogue scale (VAS) scores at the worst and in the morning and temporospatial gait parameters were evaluated at the baseline, intermediate of the intervention, end of the intervention, and the first and second month follow-up.
Results
There were significant effects of the time on the worst pain, morning pain, cadence, stride time, stride length, total double support, and gait speed, but there was no effect on step width. In addition, the main effect of the group and the interaction effects of the time and the group were not found in any parameters. For intra-group comparisons, there were significant differences in worst pain, morning pain, cadence, and stride time among the assessment times in both groups. For inter-group comparisons, there were no significant differences in all parameters.
Conclusion
Both strengthening and stretching exercise programs significantly reduced pain and improved gait in patients with PF.

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Correlation Between Mechanography and Clinical Parameters at Six Months After Hip Fracture Surgery
Tae Jun Min, Junmo Cho, Yong-Chan Ha, Jae-Young Lim, Si Hyun Kang, Don-Kyu Kim, Kyung Mook Seo, Jaewon Beom
Ann Rehabil Med 2019;43(6):642-649.   Published online December 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.6.642
Objective
To investigate the correlation between mechanography and clinical parameters in older people at 3 and 6 months after hip fracture surgery.
Methods
A longitudinal follow-up study was conducted in university hospitals with 38 patients at 3 months and 29 patients at 6 months after hip fracture surgery. Subjects 65 years and older completed measurements on the Berg Balance Scale (BBS), Functional Ambulation Category (FAC), walking ability by Koval, Korean version of the fatigue, resistance, ambulation, illnesses, and loss of weight (K-FRAIL) scale, and hand grip strength. The Romberg test with center of foot pressure (COP), chair rise test (CRT), and maximal power (W/kg) were conducted using the Leonardo Mechanograph.
Results
COP area and pathway length were correlated with BBS at 3 and 6 months. Change in BBS was correlated with change in COP area, but not with change in COP length. COP area and pathway length were correlated with K-FRAIL at 3 months after hip fracture surgery. The same COP variables showed correlations with FAC and walking ability by Koval at 6 months after surgery. Maximal power during CRT had correlation with chair rise time but not with other clinical parameters.
Conclusion
The study revealed correlations between mechanography and clinical parameters in older people at 3 and 6 months after hip fracture surgery. Both the clinical assessment and objective test with mechanography may be required for the quantitative and sensitive measurement of postural balance and lower limb muscle power.

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  • Jumping Mechanography is a Suitable Complementary Method to Assess Motor Function in Ambulatory Boys with Duchenne Muscular Dystrophy
    Astrid Blaschek, Martin Rodrigues, Rainer Rawer, Christine Müller, Lena Ille, Sebastian Schröder, Mohamed Idriess, Wolfgang Müller-Felber, Katharina Vill
    Neuropediatrics.2021; 52(06): 455.     CrossRef
  • 9,142 View
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  • 4 Crossref
Safe Needle Insertion Locations for Motor Point Injection of the Triceps Brachii Muscle: A Pilot Cadaveric and Ultrasonography Study
Hyun Jung Koo, Hye Jung Park, Geun-Young Park, Yeonjae Han, Donggyun Sohn, Sun Im
Ann Rehabil Med 2019;43(6):635-641.   Published online December 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.6.635
Objective
To determine the location of the motor endplate zones (MoEPs) for the three heads of the triceps brachii muscles during cadaveric dissection and estimate the safe injection zone using ultrasonography.
Methods
We studied 12 upper limbs of 6 fresh cadavers obtained from body donations to the medical school anatomy institution in Seoul, Korea. The locations of MoEPs were expressed as the percentage ratio of the vertical distance from the posterior acromion angle to the midpoint of the olecranon process. By using the same reference line as that used for cadaveric dissection, the safe injection zone away from the neurovascular bundle was identified in 6 healthy volunteers via ultrasonography. We identified the neurovascular bundle and its location with respect to the distal end of the humerus and measured its depth from the skin surface.
Results
The MoEPs for the long, lateral, and medial heads were located at a median of 43.8%, 54.8%, and 60.4% of the length of the reference line in cadaver dissection. The safe injection zone of the medial head MoEPs corresponded to a depth of approximately 3.5 cm from the skin surface and 1.4 cm away from the humerus, as determined by sonography.
Conclusion
Correct identification of the motor points for each head of the triceps brachii would increase the precision and efficacy of motor point injections to manage elbow extensor spasticity.

Citations

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    Hyun Jin Park, You-Jin Choi
    Toxins.2026; 18(7): 302.     CrossRef
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    Aylin Ayyıldız, Burak Tayyip Dede, Mustafa Hüseyin Temel, Bülent Alyanak, Mustafa Turgut Yıldızgören, Fatih Bağcıer
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    Camille Heslot, Omar Khan, Alexis Schnitzler, Chloe Haldane, Romain David, Rajiv Reebye
    Toxins.2024; 16(7): 304.     CrossRef
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    Kyu‐Ho Yi, Ji‐Hyun Lee, Hye‐Won Hur, Hyung‐Jin Lee, You‐Jin Choi, Hee‐Jin Kim
    Clinical Anatomy.2023; 36(7): 964.     CrossRef
  • Mapping the limb muscle motor points for targeted administration of botulinum toxin in the treatment of focal and segmental spasticity
    A. P. Kovalenko, K. A. Sinelnikov, V. D. Shamigulov, N. N. Akhmedov, E. M. Shamina
    Neurology, Neuropsychiatry, Psychosomatics.2020; 12(6): 61.     CrossRef
  • 10,123 View
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Case Report

Niemann-Pick Disease Type C Misdiagnosed as Cerebral Palsy: A Case Report
Eun Jae Ko, In Young Sung, Han-Wook Yoo
Ann Rehabil Med 2019;43(5):621-624.   Published online October 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.5.621
Niemann-Pick disease type C (NP-C) is a rare autosomal recessive neurovisceral lysosomal lipid storage disorder. The clinical manifestations of the disorder are variable. This report describes the case of a 27-month-old girl with NP-C whose condition had been misdiagnosed as spastic cerebral palsy (CP). She had spasticity, particularly at both ankles, and gait disturbance. Magnetic resonance imaging of the brain revealed findings suspicious of sequelae from a previous insult, such as periventricular leukomalacia, leading to the diagnosis of CP. However, she had a history of hepatosplenomegaly when she was a fetus and her motor development had deteriorated, with symptoms of vertical supranuclear gaze palsy, cataplexy, and ataxia developing gradually. Therefore, NP-C was considered and confirmed with a genetic study, which showed mutation of the NPC1 gene. Thus, if a child with CP-like symptoms presents with a deteriorating course and NP-C-specific symptoms, NP-C should be cautiously considered.

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    Anna M. Janzing, Erik Eklund, Tom J. De Koning, Hendriekje Eggink
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    Thora Wesenberg Helt, Lars Søndergaard Johansen, Daniel Faurholt‐Jepsen, Vibeke Andrée Larsen, Lise Borgwardt, Jann Mortensen, Vibeke Brix Christensen
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    Mercedes Cabezas-López
    Journal of Pediatric Neuropsychology.2023; 9(2): 64.     CrossRef
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    Sun Woo Park, Ji Hong Park, Hye Jeong Moon, Minsoo Shin, Jin Soo Moon, Jae Sung Ko
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Original Articles
Post-operative Physical Performance Factors Associated With Gait Speed in Patients Surgically Treated for Hip Fracture: A Cross-Sectional Study
Young Tae Jeon, Bo Ryun Kim, Eun Young Han, Kwang Woo Nam, So Young Lee, Yong Geun Park, Min Ji Suh, Jong Hyun Kim
Ann Rehabil Med 2019;43(5):570-580.   Published online October 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.5.570
Objective
To determine post-operative physical performance factors associated with gait speed in patients surgically treated for hip fracture.
Methods
Cross-sectional data from 59 patients (16 males and 43 females; mean age, 79.2±9.1 years) who underwent hip fracture surgery were enrolled. Patients completed a 10-meter walk test (10MWT) to assess gait speed. Additional physical performance tests included the Timed Up and Go test (TUG), the Berg Balance Scale (BBS), maximum voluntary isometric contraction (MVIC) of the knee extensors and flexors on the operated and non-operated sides as well as of the hip abductors (all tested using air-resistance weight machines), and analysis of spatio-temporal gait parameters at about 6 weeks after hip surgery.
Results
Bivariate analyses revealed a significant positive correlation between the post-operative 10MWT and the post-operative TUG, age, swing phase duration, and gait cycle duration along with a significant negative correlation between post-operative BBS score, MVIC of the knee extensors and flexors on the operated and non-operated sides, MVIC of the hip abductors, and cadence and stance phase duration. Linear regression analyses revealed that the post-operative TUG (β=0.85, p<0.01), gait cycle duration (β=0.17, p=0.02), and osteoporosis (β=-0.18, p=0.02) were associated with the post-operative 10MWT.
Conclusion
The presence of osteoporosis, post-operative balance, and isometric muscle strength in the operated and non-operated legs were statistically associated with post-operative gait speed early after hip fracture surgery.

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  • Association of surgical procedure and radiographic hip alignment with hip abductor strength ratio at discharge after proximal femoral fracture surgery
    Satoshi Hakukawa, Shunsuke Onuma, Kanata Yoshihara
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    Batool Abdulelah Alkhamis, Ravi Shankar Reddy, Khalid A. Alahmari, Mastour Saeed Alshahrani, Ghada Mohammed Koura, Olfat Ibrahim Ali, Debjani Mukherjee, Basant Hamdy Elrefaey, Holakoo Mohsenifar
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  • 12,093 View
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Objective
To investigate dosage changes in intrathecal baclofen during long-term treatment of patients with severe leg spasticity.
Methods
We performed a retrospective chart review of 49 patients treated with an intrathecal baclofen pump (ITB) because of severe leg spasticity, for a minimum of 7 years. Eight patients were excluded due to catheter/pump failure or factors aggravating spasticity. Of the remaining 41 patients, 19 had spinal cord injury (SCI) and 22 were diagnosed with multiple sclerosis (MS). Among the SCI patients, 15 had cervical and 4 thoracic SCI, with 7 patients showing the American Spinal Injury Association impairment scale (AIS) A and 12 patients with AIS B–D. The dose was regulated by discussion among the patients and their physicians, usually 4–10 times annually, to reduce leg spasticity and also avoid leg/trunk weakness.
Results
After 1 year patients on ITB needed a median dose of 168 mg/24 hr (range, 30–725 mg) for an optimal effect. After 7 to 10 years the dosage needed to reduce leg spasticity in the MS patients was significantly increased compared with the initial dose (mean 157%, n=22 and mean 194%, n=18). In contrast, the SCI patients needed only a modest increase (mean 113% and 121%). The difference between MS and SCI patients was significant (t-test p=0.006 and p=0.004).
Conclusion
The increased dosage in MS patients compared with patients diagnosed with SCI probably reflects the progressive disease course. The need for a large dosage increase in patients with SCI suggests possible pump failure, triggering factors for spasticity or progressive spinal disease.

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    Abdulaziz Al Mosallam, Ahmad Zaheer Qureshi, Anas J. AlSaleh
    The Journal of the International Society of Physical and Rehabilitation Medicine.2025; 8(2): 50.     CrossRef
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    Radha Korupolu, Melanie Quoilin, Benjamin Ballard, Jacob Frentzen
    The Journal of Spinal Cord Medicine.2025; : 1.     CrossRef
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    James W Leiphart, Thaddeus J Leiphart
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    Zackery J. Billington, Austin M. Henke, David R. Gater
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    Hasan Burak Gündüz
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Effect of Decreased Skeletal Muscle Index and Hand Grip Strength on Functional Recovery in Subacute Ambulatory Stroke Patients
Jin Gee Park, Kyeong Woo Lee, Sang Beom Kim, Jong Hwa Lee, Young Hwan Kim
Ann Rehabil Med 2019;43(5):535-543.   Published online October 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.5.535
Objective
To investigate the effect of decreased Skeletal Muscle Index (SMI) and hand grip strength on functional recovery in subacute ambulatory stroke patients.
Methods
Subacute stroke patients who were referred to the rehabilitation center were recruited. Decreased SMI and hand grip strength were diagnosed according to the Asian Working Group on Sarcopenia. Diagnostic criteria were decreased SMI and decreased unaffected hand grip strength. SMI was measured by bioelectrical impedance analysis. Unaffected hand grip strength was measured with a hand dynamometer. Patients were divided into two groups, decreased group (DG) and not-decreased group (NDG), according to the presence of decreased SMI and hand grip strength. Both groups received conventional stroke rehabilitation for 3 weeks. All patients were evaluated at the baseline and at 3 weeks after treatment. Functional status was evaluated with 4-meter walk test (4MWT), 6-minute walk test (6MWT), Timed Up and Go test (TUG), and Modified Barthel Index (MBI).
Results
Both groups showed improvement in 4MWT, TUG, and MBI. NDG showed improvement in 6MWT. Comparing improvements between the two groups, NDG showed more improvement in 6MWT and TUG than DG.
Conclusion
The presence of decreased SMI and hand grip strength had negative effects on functional recovery in subacute ambulatory stroke patients.

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Effect of Sensory Impairment on Balance Performance and Lower Limb Muscle Strength in Older Adults With Type 2 Diabetes
Ratchanok Kraiwong, Mantana Vongsirinavarat, Vimonwan Hiengkaew, Petra von Heideken Wågert
Ann Rehabil Med 2019;43(4):497-508.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.497
Objective
To compare balance performance and lower limb muscle strength between older adults with type 2 diabetes mellitus (DM), with and without sensory impairments and non-DM groups. Influence of a number of sensory impairments, and muscle strength on balance performance were explored.
Methods
Ninety-two older adults with and without type 2 DM, were examined relative to visual function with the Snellen chart, Melbourne Edge test, and Howard-Dolman test, vestibular function with the modified Romberg test, proprioception of the big toe, and diabetic peripheral neuropathy with the Michigan Neuropathy Screening Instrument. Balance performances were evaluated with the Romberg test, Functional Reach Test (FRT), and Timed Up and Go test (TUG). Strength of knee and ankle muscles was measured.
Results
FRT of type 2 DM groups with at least two sensory impairments, was lower than the non-DM group (p<0.05). TUG of all DM groups, was worse than the non-DM group (p<0.01). Lower limb muscle strength of type 2 DM groups with two and three sensory impairments, was weaker than non-DM group (p<0.05). Regression analysis showed that type 2 DM with three sensory impairments, ankle dorsiflexors strength, and age were influential predictors of TUG.
Conclusion
There were significant differences, of muscle strength and balance performance among groups. Poorer balance and reduced lower limb strength were marked in older adults with type 2 DM, even ones without sensory impairment. Muscle weakness seemed to progress, from the distal part of lower limbs. A greater number of sensory impairments, weaker dorsiflexors, and advanced age influenced balance performance.

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Effect of Pre-training and Post-training Nordic Exercise on Hamstring Injury Prevention, Recurrence, and Severity in Soccer Players
Ahmed Ebrahim Elerian, Mohsen M. El-Sayyad, Hend Adel Abdelhalim Dorgham
Ann Rehabil Med 2019;43(4):465-473.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.465
Objective
To investigate the effect of adding Nordic exercise as post-training in decreasing hamstring initial, recurrent injuries rates, and their severity.
Methods
In this randomly controlled trial study, 34 professional football players aged 21 to 35 years were randomly assigned into two groups (17 players each) from Sporting clubs at Alexandria, Egypt. For group one, Nordic hamstring exercise (NHE) was performed pre-training and post-training. For group two, NHE was only performed pre-training. The control group was the same team during the previous season. Length of the trial was 12 weeks. The Australian football association injury form was used to collect incidence of injuries for each subject in both groups.
Results
Pooled results based on total injuries showed that group one had significantly less hamstring initial injuries (92% less) than the previous season, while group two had 80% less initial injuries and 85% less recurrent injuries than previous season. Regarding the severity of injuries in term of mean number of absent days, it was 1 day for group one and 2.7 days for group two while it was 7.95 days for the previous season during total risk time of 116.3±13.2 and 117.6±5.7 exposure hours for group one and group two, respectively.
Conclusion
The use of NHE as a prevention protocol was effective in reducing all hamstring injuries with the use of NHE during pre-training and post-training having the greatest effect.

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The Role of Regular Physical Therapy on Spasticity in Children With Cerebral Palsy
Heewon Lee, Eun Kyung Kim, Dong Baek Son, Youngdeok Hwang, Joon-Sung Kim, Seong Hoon Lim, Bomi Sul, Bo Young Hong
Ann Rehabil Med 2019;43(3):289-296.   Published online June 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.3.289
Objective
To investigate the effect of physical therapy (PT) intervention on spasticity in patients with cerebral palsy (CP), and to assess the degree of deterioration of spasticity when regular PT is interrupted in those patients.
Methods
We recruited 35 children with spastic CP who visited our hospital for PT, and whose Modified Tardieu Scale (MTS) scores were serially recorded including before and after a 10-day public holiday time frame period. The outcome measures were the angle of range of motion (ROM) of dorsiflexion of the ankle joint (R1 and R2) in the knee flexion and extension positions as assessed using the MTS.
Results
The range of dorsiflexion of the ankle joint (R1 and R2) after the holiday period was significantly decreased as compared with that measured ROM noted before the holiday period, regardless of the knee position, age, or gross motor function. The dynamic component of the MTS (R2–R1) showed a slight decrease in the knee flexion position.
Conclusion
Interruption of regular PT aggravated spasticity and decreased ankle joint ROM in children with spastic CP. Our findings suggest that regular PT in the care continuum for children with CP is crucial for the maintenance of ROM in the spastic ankle joints.

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    Włodzisław Kuliński, Emilia Gryl
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Duration of Treatment Effect of Extracorporeal Shock Wave on Spasticity and Subgroup-Analysis According to Number of Shocks and Application Site: A Meta-Analysis
Jae Ho Oh, Hee Dong Park, Seung Hee Han, Ga Yang Shim, Kyung Yeul Choi
Ann Rehabil Med 2019;43(2):163-177.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.163
Objective
To investigate duration of the treatment effect of extracorporeal shockwave therapy (ESWT) on spasticity levels measured with Modified Ashworth Scale (MAS) regardless of the patient group (stroke, multiple sclerosis, and cerebral palsy) and evaluate its spasticity-reducing effect depending on the number of shocks and site of application.
Methods
PubMed, EMBASE, the Cochrane Library, and Scopus were searched from database inception to February 2018. Randomized controlled trials and cross-over trials were included. All participants had spasticity regardless of cause. ESWT was the main intervention and MAS score was the primary outcome. Among 122 screened articles, 9 trials met the inclusion criteria.
Results
The estimate of effect size showed statistically significant MAS grade reduction immediately after treatment (standardized mean difference [SMD]=-0.57; 95% confidence interval [CI], -1.00 to -0.13; p=0.012), 1 week after (SMD=-1.81; 95% CI, -3.07 to -0.55; p=0.005), 4 weeks after (SMD=-2.35; 95% CI, -3.66 to -1.05; p<0.001), and 12 weeks after (SMD=-1.07; 95% CI, -2.04 to -0.10; p=0.03). Meta-regression and subgroup analysis were performed for the ‘immediately after ESWT application’ group. The prediction equation obtained from metaregression was -1.0824+0.0002* (number of shocks), which was not statistically significant. Difference in MAS grade reduction depending on site of application was not statistically significant either in subgroup analysis (knee and ankle joints vs. elbow, wrist, and finger joints).
Conclusion
ESWT effectively reduced spasticity levels measured with MAS regardless of patient group. Its effect maintained for 12 weeks. The number of shocks or site of application had no significant influence on the therapeutic effect of ESWT in reducing spasticity. Ongoing trials with ESWT are needed to address optimal parameters of shock wave to reduce spasticity regarding intensity, frequency, and numbers.

Citations

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    Shu-Mei YANG, Shao-Yu CHEN, Kuan-Yu CHEN, Ting-Ju LAI, Meng-Ting LIN
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    Yide WANG, Qianqian LIANG, Xiangpeng LI, Siming TAO, Rong BIAN
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    Boris S.G. Hellenbrand, Charlotte C.M. van Laake – Geelen, Henk A.M. Seelen
    The Journal of Spinal Cord Medicine.2025; 48(3): 429.     CrossRef
  • Using Radial Shock Wave Therapy to Control Cerebral Palsy-Related Dysfunctions: A Randomized Controlled Trial
    Hisham Hussein, Ahmed Gabr, Monira Aldhahi, Amsha Alshammari, Hand Alshammari, Khulood Altamimi, Abdulaziz Alqahtani, Ibrahim Dewir, Shamekh El-Shamy, Ahmed Ibrahim
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    Takatsugu Okamoto, Takumi Watanabe, Shogo Uemori
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    Mohammed A Khan, Nada M Aljohani, Saad A AlSehemi, Salma A Abdelhamid, Omar A Alahmadi, Abdulmajeed Y Altohami, Abdullah A Shweikan, Mohammad K Aljohani
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    Sheng Li, Paul Winston, Manuel F. Mas
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    Ting-Yu Su, Yu-chi Huang, Jih-Yang Ko, Yi-Jung Hsin, Min-Yuan Yu, Pi-Lien Hung
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    Ileana M. Howard, Atul T. Patel
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    Irem Onin, Hatice Kumru, Monserrat Bernabeu, Giuseppe Lucente
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Effects of Neuromuscular Electrical Stimulation for Masseter Muscle on Oral Dysfunction After Stroke
Kyeong Woo Lee, Sang Beom Kim, Jong Hwa Lee, Sook Joung Lee, Jin Gee Park, Kyung Won Jang
Ann Rehabil Med 2019;43(1):11-18.   Published online February 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.1.11
Objective
To determine positive effect of neuromuscular electrical stimulation (NMES) in conventional dysphagia therapy on masseter muscle oral dysfunction of patients after subacute stroke.
Methods
Among subacute stroke patients who were diagnosed as oropharyngeal dysphagia by videofluoroscopy swallowing study (VFSS), those with oral dysfunction were enrolled. They were randomly assigned to a study group or a control group. The study group received NMES on masseter muscle and suprahyoid muscle simultaneously, while the control group received NMES only on suprahyoid muscle. NMES therapy session as applied 30 minutes each time, two times per day for a total of 20 sessions. Both groups received conventional dysphagia therapy for 2 weeks. All enrolled patients were evaluated by VFSS after 2 weeks. Oropharyngeal swallowing function was evaluated by Penetration-Aspiration Scale, Functional Dysphagia Scale (FDS), and American Speech-Language-Hearing Association National Outcome Measurement System swallowing scale based on results of VFSS.
Results
Patients were randomly assigned to the study group (n=20) or the control group (n=20). There were no significant differences in baseline characteristics or initial values between the two groups. After 2 weeks of NMES, both groups showed improvement in scores of total FDS and pharyngeal phase FDS. Additionally, the study group showed improvement in oral phase FDS. Changes in all measurements were similar between the two groups.
Conclusion
In this preliminary study, NMES for masseter muscle has a therapeutic effect on oral dysfunction of patients after subacute stroke.

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    Seoyon Yang, You Gyoung Yi
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    Ibrahim M. Alayaseh, Ponnusamy Subramaniam, Thanzeem Razak, Yaser S. Natour, Marissa A. Barrera, Shobha Sharma
    Dysphagia.2026; 41(3): 657.     CrossRef
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    Muhan Zhou, Baoqiang Dong, Hongfei Zhou, Wei Zhang, Aihui Fu, Zhiqiang Sun, Xi Wu
    Frontiers in Neuroscience.2026;[Epub]     CrossRef
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    Frauke Johannes, Anna Maria Pekacka-Egli, Simone Köhler, Andreas Disko, Jan von Meyenburg, Bartosz Bujan
    Brain Sciences.2025; 15(4): 410.     CrossRef
  • Gum Chewing Exercise Synchronised With Neuromuscular Electrical Stimulation is Better Than Gum Chewing Exercise Alone for Improving Masticatory Function and Mucosal Moisture in Older Adults With Sarcopenic Dysphagia
    Ji‐Su Park, Jong‐Bae Choi, Na‐Kyoung Hwang
    Journal of Oral Rehabilitation.2025; 52(9): 1420.     CrossRef
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    Bendix Labeit, Emilia Michou, Michaela Trapl-Grundschober, Sonja Suntrup-Krueger, Paul Muhle, Philip M Bath, Rainer Dziewas
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  • The Effects of Neuromuscular Electrical Stimulation on Swallowing Functions in Post-stroke Dysphagia: A Randomized Controlled Trial
    Elif Tarihci Cakmak, Ekin Ilke Sen, Can Doruk, Comert Sen, Selim Sezikli, Ayse Yaliman
    Dysphagia.2023; 38(3): 874.     CrossRef
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    Yuhan Wang, Lu Xu, Linjia Wang, Minjiao Jiang, Ling Zhao
    Frontiers in Neurology.2023;[Epub]     CrossRef
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    James C. Borders, Alessandro A. Grande, Michelle S. Troche
    Dysphagia.2022; 37(6): 1673.     CrossRef
  • Therapeutic Effect and Optimal Electrode Placement of Transcutaneous Neuromuscular Electrical Stimulation in Patients with Post-Stroke Dysphagia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Thanh-Nhan Doan, Wen-Chao Ho, Liang-Hui Wang, Fei-Chun Chang, Trang Thi Quynh Tran, Li-Wei Chou
    Life.2022; 12(6): 875.     CrossRef
  • The Facial Skin Blood Flow Change of Stroke Patients with Facial Paralysis after Peripheral Magnetic Stimulation: A Pilot Study
    Yongli Zhang, Shugeng Chen, Yinglu Ruan, Jiaying Lin, Chengdong Li, Chong Li, Shuo Xu, Zhijie Yan, Xiangyun Liu, Peng Miao, Jie Jia
    Brain Sciences.2022; 12(10): 1271.     CrossRef
  • Effect of Neuromuscular Electrical Stimulation on Masseter Muscle Thickness and Maximal Bite Force among Healthy Community-Dwelling Persons Aged 65 Years and Older: A Randomized, Double Blind, Placebo-Controlled Study
    Moon-Young Chang, Gihyoun Lee, Young-Jin Jung, Ji-Su Park
    International Journal of Environmental Research and Public Health.2020; 17(11): 3783.     CrossRef
  • Effects of Neuromuscular Electrical Stimulation Synchronized with Chewing Exercises on Bite Force and Masseter Muscle Thickness in Community-Dwelling Older Adults in South Korea: A Randomized Controlled Trial
    Ji-Su Park, Young-Jin Jung, Min-Ji Kim
    International Journal of Environmental Research and Public Health.2020; 17(13): 4902.     CrossRef
  • Effectiveness of Different Application Parameters of Neuromuscular Electrical Stimulation for the Treatment of Dysphagia after a Stroke: A Systematic Review
    Isabel Diéguez-Pérez, Raquel Leirós-Rodríguez
    Journal of Clinical Medicine.2020; 9(8): 2618.     CrossRef
  • Effectiveness of Neuromuscular Electrical Stimulation on Post-Stroke Dysphagia: A Systematic Review of Randomized Controlled Trials


    Abayneh Alamer, Haimanot Melese, Fetene Nigussie
    Clinical Interventions in Aging.2020; Volume 15: 1521.     CrossRef
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Effect of Whole Body Horizontal Vibration Exercise in Chronic Low Back Pain Patients: Vertical Versus Horizontal Vibration Exercise
Heejae Kim, Bum Sun Kwon, Jin-Woo Park, Hojun Lee, Kiyeun Nam, Taejune Park, Yongjin Cho, Taeyeon Kim
Ann Rehabil Med 2018;42(6):804-813.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.804
Objective
To elucidate the effect of a 12-week horizontal vibration exercise (HVE) in chronic low back pain (CLBP) patients as compared to vertical vibration exercise (VVE).
Methods
Twenty-eight CLBP patients were randomly assigned to either the HVE or VVE group. All participants performed the exercise for 30 minutes each day, three times a week, for a total of 12 weeks. Altered pain and functional ability were evaluated using the visual analog scale (VAS) and Oswestry Disability Index (ODI), respectively. Changes in lumbar muscle strength, transverse abdominis (TrA) and multifidus muscle thicknesses, and standing balance were measured using an isokinetic dynamometer, ultrasonography, and balance parameters, respectively. These assessments were evaluated prior to treatment, 6 weeks and 12 weeks after the first treatment, and 4 weeks after the end of treatment (that is, 16 weeks after the first treatment).
Results
According to the repeated-measures analysis of variance, there were significant improvements with time on VAS, ODI, standing balance score, lumbar flexor, and extensor muscle strength (all p<0.001 in both groups) without any significant changes in TrA (p=0.153 in HVE, p=0.561 in VVE group) or multifidus (p=0.737 in HVE, p=0.380 in VVE group) muscle thickness. Further, there were no significant differences between groups according to time in any of the assessments. No adverse events were noticed during treatment in either group.
Conclusion
HVE is as effective as VVE in reducing pain, strengthening the lumbar muscle, and improving the balance and functional abilities of CLBP patients. Vibrational exercise increases muscle strength without inducing muscle hypertrophy.

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    Kaitlin D. Lyons, Aaron G. Parks, Oluwagbemiga Dadematthews, Nilophar Zandieh, Paige McHenry, Kenneth E. Games, Michael D. Goodlett, William Murrah, Jaimie Roper, JoEllen M. Sefton
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Comparison Between Neuromuscular Electrical Stimulation to Abdominal and Back Muscles on Postural Balance in Post-stroke Hemiplegic Patients
Mingeun Park, Hyun Seok, Sang-Hyun Kim, Kyudong Noh, Seung Yeol Lee
Ann Rehabil Med 2018;42(5):652-659.   Published online October 31, 2018
DOI: https://doi.org/10.5535/arm.2018.42.5.652
Objective
To compare the effects of neuromuscular electrical stimulation (NMES) to abdominal muscles and back muscles on postural balance in post-stroke hemiplegic patients.
Methods
Thirty post-stroke hemiplegic patients were prospectively enrolled and randomly assigned to one of the three groups: core muscle-strengthening exercise (CME) with NMES to abdominal muscles (group A), CME with NMES to back muscles (group B), and CME alone (group C). All subjects underwent their targeted interventions for 30 minutes each day, 5 days per week for 3 weeks under a conventional stroke rehabilitation program. Subjects were evaluated using Korean version of Berg Balance Scale (K-BBS), Trunk Impairment Scale (TIS), Korean version of Modified Barthel Index (K-MBI), Weight Distribution Index (WDI), and Stability Index (SI) just before and 3 weeks after intervention.
Results
Changes in K-BBS (p<0.05) and TIS (p<0.05) were significantly higher in group A (18.5±8.10, 6.6±1.90) and group B (19.9±5.44, 7.0±2.26) than in group C (8.4±4.14, 3.1±0.99). However, K-MBI, WDI, and SI failed to show any significant difference. No significant difference in all outcomes was observed between groups A and B.
Conclusion
The effect of NMES to the abdominal muscles was similar to the effect on back muscles in terms of postural balance. This finding indicated that the NMES to the abdominal muscles may be an alternative for post-stroke hemiplegic patients contraindicated for NMES to the back muscles. Additional studies investigating the effects of NMES on abdominal and back muscles are needed.

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Quantitative Evaluation of Post-stroke Spasticity Using Neurophysiological and Radiological Tools: A Pilot Study
Mi Jin Hong, Jong Bum Park, Yung Jin Lee, Hyeong Tae Kim, Won Chul Lee, Cheol Mog Hwang, Hyun Kyoon Lim, Dong Hyun Lee
Ann Rehabil Med 2018;42(3):384-395.   Published online June 27, 2018
DOI: https://doi.org/10.5535/arm.2018.42.3.384
Objective
To determine the possibility of a new measurement tool using electromyography and ultrasonography for quantitative spasticity assessment in post-stroke patients.
Methods
Eight hemiplegic stroke patients with ankle plantarflexor spasticity confirmed by a Modified Ashworth Scale (MAS) were enrolled. Spasticity was evaluated using the MAS and Modified Tardieu Scale (MTS). Each subject underwent surface electromyography (sEMG) using the Brain Motor Control Assessment (BMCA) protocol and was compared with a healthy control group. Using ultrasonography, muscle architecture and elasticity index were measured from the medial gastrocnemius muscle (GCM) on the affected and unaffected sides.
Results
MAS and MTS revealed significant correlation with sEMG activity. The fascicle length and pennation angle were significantly decreased in the medial GCM on the hemiplegic side compared with the unaffected side. The elasticity index of the spastic medial GCM was significantly increased compared with the unaffected side. The MTS X and R2–R1 values were significantly correlated with the elasticity index in the hemiplegic GCM. The relationship between clinical evaluation tools and both BMCA and sonoelastography was linear, but not statistically significant in the multiple regression analysis.
Conclusion
The BMCA protocol and ultrasonographic evaluation provide objective assessment of post-stroke spasticity. Further studies are necessary to conduct accurate assessment and treatment of spasticity.

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Relationship Between Functional Level and Muscle Thickness in Young Children With Cerebral Palsy
Yeo Reum Choe, Joo Sup Kim, Kee Hoon Kim, Tae Im Yi
Ann Rehabil Med 2018;42(2):286-295.   Published online April 30, 2018
DOI: https://doi.org/10.5535/arm.2018.42.2.286
Objective

To investigate the relationship between functional level and muscle thickness (MT) of the rectus femoris (RF) and the gastrocnemius (GCM) in young children with cerebral palsy (CP).

Methods

The study participants were comprised of 26 children (50 legs) with spastic CP, aged 3–6 years, and 25 age-matched children with typical development (TD, 50 legs). The MT of the RF, medial GCM, and lateral GCM was measured with ultrasound imaging. The functional level was evaluated using the Gross Motor Function Measurement-88 (GMFM-88), Gross Motor Function Classification System (GMFCS), and based on the mobility area of the Korean version of the Modified Barthel Index (K-MBI). The measurement of spasticity was evaluated with the Modified Ashworth Scale (MAS).

Results

We note that the height, weight, body mass index, and MT of the RF, and the medial and lateral GCM were significantly higher in the TD group (p<0.05). There was a direct relationship between MT of the RF and medial GCM and the GMFM-88, GMFCS, and mobility scores of the K-MBI in individuals with early CP. In addition, we have noted that there was a direct relationship between MT of the lateral GCM and the GMFM-88 and GMFCS. Although there was a tendency toward lower MT with increasing MAS ratings in the knee and ankle, the correlation was not statistically significant.

Conclusion

In young children with CP, MT of the RF and GCM was lower than in age-matched children with TD. Furthermore, it is noted with confidence that a significant positive correlation existed between MT and functional level as evaluated using the GMFM-88, GMFCS, and mobility area of K-MBI.

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Determinants of Hip and Femoral Deformities in Children With Spastic Cerebral Palsy
Yoona Cho, Eun Sook Park, Han Kyul Park, Jae Eun Park, Dong-wook Rha
Ann Rehabil Med 2018;42(2):277-285.   Published online April 30, 2018
DOI: https://doi.org/10.5535/arm.2018.42.2.277
Objective

To find factors affecting hip and femoral deformities in children with spastic cerebral palsy (CP) by comparing various clinical findings with imaging studies including plain radiography and computed tomography (CT) imaging.

Methods

Medical records of 709 children with spastic CP who underwent thorough baseline physical examination and functional assessment between 2 to 6 years old were retrospectively reviewed. Fifty-seven children (31 boys and 26 girls) who had both plain radiography of the hip and three-dimensional CT of the lower extremities at least 5 years after baseline examination were included in this study.

Results

The mean age at physical examination was 3.6 years (SD=1.6; range, 2–5.2 years) and the duration of follow-up imaging after baseline examination was 68.4 months (SD=22.0; range, 60–124 months). The migration percentage correlated with motor impairment and the severity of hip adductor spasticity (R1 angle of hip abduction with knee flexion). The femoral neck and shaft angle correlated with the ambulation ability and severity of hip adductor spasticity (R1 and R2 angles of hip abduction with both knee flexion and extension).

Conclusion

Hip subluxation and coxa valga deformity correlated with both dynamic spasticity and shortening of hip adductor muscles. However, we found no correlation between femoral deformities such as femoral anteversion, coxa valga, and hip subluxation.

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Quantitative Measurement of Muscle Atrophy and Fat Infiltration of the Supraspinatus Muscle Using Ultrasonography After Arthroscopic Rotator Cuff Repair
Yong Ki Kim, Eun Seok Choi, Keon Tae Kim, Jung Ro Yoon, Sang Han Chae
Ann Rehabil Med 2018;42(2):260-269.   Published online April 30, 2018
DOI: https://doi.org/10.5535/arm.2018.42.2.260
Objective

To investigate the utility of ultrasonography to objectively examine morphological changes (i.e., muscle atrophy and fatty infiltration) of the supraspinatus muscle.

Methods

Thirty-four patients were prospectively enrolled in this study. The degrees of muscle atrophy and fat infiltration were measured using ultrasonography 3–4 months after arthroscopic supraspinatus tendon repair. Shoulder function (i.e., shoulder active range of motion, visual analogue scale, and constant score) was examined. Using the symmetricity of the muscles in the human body, the degrees of morphological changes of the supraspinatus muscle were quantitatively measured. The associations between the morphological changes of the supraspinatus muscle and shoulder function were identified.

Results

There were statistically significant differences in the cross-sectional area (CSA) and echogenicity between the surgery and non-surgery sides (p<0.001). The CSA ratio, which represents the degree of muscle atrophy, was associated with shoulder forward flexion, external rotation, and constant score; however, the echogenicity ratio, which represents the degree of fat infiltration, was not associated with shoulder function after surgery.

Conclusion

This study demonstrated that shoulder function could be predicted by evaluating the morphological changes of the supraspinatus muscle using ultrasonography and that objective evaluation is possible through quantitative measurement using the symmetricity of the human body.

Citations

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    Vincent Martinel, Marie Faruch, Maxime Pastor, Geoffroy Nourissat
    Revue de Chirurgie Orthopédique et Traumatologique.2025; 111(6): 720.     CrossRef
  • Investigating the relationship between quantitative‐based ultrasound and MRI estimations of rotator cuff fatty infiltration
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Effects of Very High Stimulation Frequency and Wide-Pulse Duration on Stimulated Force and Fatigue of Quadriceps in Healthy Participants
Kitima Rongsawad, Jonjin Ratanapinunchai
Ann Rehabil Med 2018;42(2):250-259.   Published online April 30, 2018
DOI: https://doi.org/10.5535/arm.2018.42.2.250
Objective

To determine the effect of very high stimulation frequency (150 and 200 Hz) with wide pulse duration versus 50 Hz with wide pulse duration on stimulated force and fatigue of quadriceps femoris in healthy participants.

Methods

Thirty-four healthy participants underwent fatigue test using three stimulation frequency conditions (50, 150, and 200 Hz) with pulse duration of 0.9 ms. Normalized force values at the end of each fatigue protocol and curve fitting patterns were compared among stimulated frequencies.

Results

Very high stimulation frequency (150 and 200 Hz) conditions showed a trend of having more decline in normalized stimulated force during fatigue test compared to a low stimulation frequency at 50 Hz. However, the difference was not statistically significant. Responder group showed the same slope of a linear fitting pattern, implying the same pattern of muscle fatigue among three stimulation frequency conditions (−3.32 in 50 Hz, −2.88 in 150 Hz, and −3.14 in 200 Hz, respectively).

Conclusion

There were high inter-subject variations in the response to different frequency stimulation conditions. However, very high stimulation frequency generated the same fatigue pattern as the low stimulation frequency in the responder group. Further research is needed to explore the mechanism involved.

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  • 13,379 View
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  • 7 Web of Science
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