Objective
To examine the association between the mobilization level during intensive care unit (ICU) admission and independence in activity of daily living (ADL), defined as Barthel Index (BI)≥70.
Methods
This was a post-hoc analysis of the EMPICS study involving nine hospitals. Consecutive patients who spend >48 hours in the ICU were eligible for inclusion. Mobilization was performed at each hospital according to the shared protocol and the highest ICU mobility score (IMS) during the ICU stay, baseline characteristics, and BI at hospital discharge. Multiple logistic regression analysis, adjusted for baseline characteristics, was used to deter-mine the association between the highest IMS (using the receiver operating characteristic [ROC]) and ADL.
Results
Of the 203 patients, 143 were assigned to the ADL independence group and 60 to the ADL dependence group. The highest IMS score was significantly higher in the ADL independence group than in the dependence group and was a predictor of ADL independence at hospital discharge (odds ratio, 1.22; 95% confidence interval, 1.07–1.38; adjusted p=0.002). The ROC cutoff value for the highest IMS was 6 (specificity, 0.67; sensitivity, 0.70; area under the curve, 0.69).
Conclusion
These results indicate that, in patients who were in the ICU for more than 48 hours, that patients with good function in the ICU also exhibit good function upon discharge. However, prospective, multicenter trials are needed to confirm this conclusion.

Citations

• Association between changes in disease severity and physical function after surviving a critical illness: A multicentre retrospective observational study
  Keibun Liu, Tomohiro Hamagami, Naoki Sugiyasu, Kenji Fujizuka, Akira Kawauchi, Sou Yamada, Takayuki Ogura, Naoko Hirata, Takafumi Tani, Shunsuke Taito, Kohei Ota, David McWilliams, Hajime Katsukawa, Toru Kotani
  Australian Critical Care.2024; 37(6): 889.     CrossRef

Objective
To discuss the association between the length of stay at the intensive care unit (ICU) and sarcopenia among hemiplegic stroke patients.
Methods
This study evaluated 66 hemiplegic stroke patients with history of ICU admission using handgrip strength and bioelectrical impedance analysis to obtain height-adjusted appendicular skeletal muscle mass. The diagnosis of sarcopenia was made according to the muscle mass based on the Asian Working Group for Sarcopenia. The patients were divided into sarcopenic and non-sarcopenic groups. The two groups were statistically analyzed, and the significant factors with differences were studied. A multivariate logistic regression analysis was performed to examine the association between length of stay in the ICU and sarcopenia, after adjusting for potential confounders.
Results
Among 66 hemiplegic patients with an ICU admission history, 12 patients were diagnosed with sarcopenia. Sarcopenia patients showed lower scores on the Korean version of the Modified Barthel Index and the Korean version of the Mini-Mental State Examination. Additionally, patients with sarcopenia had a longer length of stay in the ICU, and univariate and multivariate analyses confirmed that the ICU length of stay was significantly related to sarcopenia (adjusted odds ratio=1.187; 95% confidence interval, 1.019–1.382; p=0.028).
Conclusion
The length of stay in the ICU was significantly associated with sarcopenia in hemiplegic stroke patients.

Citations

• Usefulness of body composition assessment by bioelectrical impedance vector analysis in subacute post-stroke patients in rehabilitation
  Alessandro Guerrini, Mariacristina Siotto, Carola Cocco, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Stefania Lattanzi, Sabina Insalaco, Yeganeh Manon Khazrai, Irene Giovanna Aprile
  Scientific Reports.2025;[Epub]     CrossRef
• Indirect calorimetry directed feeding and cycling in the older ICU population: a pilot randomised controlled trial
  Ng Shu Hui Elizabeth, Tan Yanni, Leong Siaw May, Tiong Hui Fen, Li Xuanhui Janice, Kwan Peijun, Ong Sze Pheng, Toh Shi Jie, Loh Ne Hooi Will
  BMC Anesthesiology.2024;[Epub]     CrossRef
• Effects of Brunnstrom movement therapy versus mirror therapy on hand function in post-stroke hemiplegic population
  Nimra, Ayesha Zulifiqar, Muhammad Umair Javaid, Reham Ali Mohamed Ali Ahmed
  Journal of Musculoskeletal Surgery and Research.2024; 8: 389.     CrossRef
• Association between handgrip strength and small airway disease in patients with stable chronic obstructive pulmonary disease
  Thanapon Keawon, Narongkorn Saiphoklang
  Therapeutic Advances in Respiratory Disease.2024;[Epub]     CrossRef
• Trunk Impairment Scale for Predicting Lumbar Spine Bone Mineral Density in Young Male Patients With Subacute Stroke
  Yeon Hee Cho, Hyun Seok, Sang-Hyun Kim, Seung Yeol Lee, Hyun Jung Kim
  Annals of Rehabilitation Medicine.2023; 47(2): 98.     CrossRef
• Accuracy of Calf Circumference Measurement, SARC-F Questionnaire, and Ishii's Score for Screening Stroke-Related Sarcopenia
  Ruihong Yao, Liqing Yao, Changli Yuan, Bu-Lang Gao
  Frontiers in Neurology.2022;[Epub]     CrossRef
• Natural aging course of lumbar extensor muscle mass and strength in community-dwelling older women: a 1-year prospective observational study
  Dong Hyun Kim, Jinhee Park, Chang Won Lee, Sang Yoon Lee
  Aging Clinical and Experimental Research.2022; 34(9): 2099.     CrossRef
• Prognostic Value of Isolated Sarcopenia or Malnutrition–Sarcopenia Syndrome for Clinical Outcomes in Hospitalized Patients
  Iasmin Matias Sousa, Camila Ferri Burgel, Flávia Moraes Silva, Ana Paula Trussardi Fayh
  Nutrients.2022; 14(11): 2207.     CrossRef
• Effects of leucine-rich protein supplements in older adults with sarcopenia: A systematic review and meta-analysis of randomized controlled trials
  Sang Yoon Lee, Hyun Jeong Lee, Jae-Young Lim
  Archives of Gerontology and Geriatrics.2022; 102: 104758.     CrossRef
• Relationship between Nutritional Status, Food Consumption and Sarcopenia in Post-Stroke Rehabilitation: Preliminary Data
  Mariacristina Siotto, Marco Germanotta, Alessandro Guerrini, Simona Pascali, Valeria Cipollini, Laura Cortellini, Elisabetta Ruco, Yeganeh Manon Khazrai, Laura De Gara, Irene Aprile
  Nutrients.2022; 14(22): 4825.     CrossRef
• Handgrip Strength: An Irreplaceable Indicator of Muscle Function
  Sang Yoon Lee
  Annals of Rehabilitation Medicine.2021; 45(3): 167.     CrossRef