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Original Articles

Ultrasonographic Analysis of Optimal Needle Placement for Extensor Indicis
Jin Young Kim, Hyun Seok, Sang-Hyun Kim, Yoon-Hee Choi, Jun Young Ahn, Seung Yeol Lee
Ann Rehabil Med 2020;44(6):450-458.   Published online December 31, 2020
DOI: https://doi.org/10.5535/arm.20035
Objective
To determine the most optimal needle insertion point of extensor indicis (EI) using ultrasound.
Methods
A total 80 forearms of 40 healthy volunteers were recruited. We identified midpoint (MP) of EI using ultrasound and set MP as optimal needle insertion point. The location of MP was suggested using distances from landmarks. Distance from MP to medial border of ulna (MP-X) and to lower margin of ulnar head (MP-Y) were measured. Ratios of MP-X to Forearm circumference (X ratio) and MP-Y to forearm length (Y ratio) were calculated. In cross-sectional view, depth of MP (Dmp), defined as middle value of superficial depth (Ds) and deep depth (Dd) was measured and suggested as proper depth of needle insertion.
Results
Mean MP-X was 1.37±0.14 cm and mean MP-Y was 5.50±0.46 cm. Mean X ratio was 8.10±0.53 and mean Y ratio was 22.15±0.47. Mean Dmp was 7.63±0.96 mm.
Conclusion
We suggested that novel optimal needle insertion point of the EI. It is about 7.6 mm in depth at about 22% of the forearm length proximal from the lower margin of the ulnar head and about 8.1% of the forearm circumference radial from medial border of ulna.
  • 5,097 View
  • 175 Download
Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Polydeoxyribonucleotide in the Treatment of Knee Osteoarthritis
Seihee Yoon, Jung Joong Kang, Jungin Kim, Seunghun Park, Jong Moon Kim
Ann Rehabil Med 2019;43(2):204-214.   Published online April 30, 2019
DOI: https://doi.org/10.5535/arm.2019.43.2.204
Objective
To assess the clinical efficacy and safety of intra-articular injection of hyaluronic acid (HA) combined with polydeoxyribonucleotide (PDRN) in patients with knee osteoarthritis in comparison with that of HA alone.
Methods
The current single-center, prospective, randomized, double-blind, controlled study was conducted in 36 patients with knee osteoarthritis at our medical institution. All the eligible patients (n=30) were equally assigned to two treatment arms (trial group ‘HA+PDRN’ and control group ‘HA’). For efficacy assessment, the patients were evaluated for the visual analogue scale (VAS) scores, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the Knee Society Scores (KSS), all of which served as efficacy outcome measures. We monitored time-dependent changes in efficacy outcome measures at baseline and 1, 3 and 6 months. Subsequently, we compared differences in changes in efficacy outcome measures at 6 months from baseline between the two groups. Moreover, we assessed the safety based on the treatment-emergent adverse events (TEAEs), adverse drug reactions (ADRs) and any other complications serving as safety outcome measures.
Results
There were significant differences in changes in the VAS scores, the WOMAC scores in all domains, except ‘Stiffness’, the total WOMAC scores, and the KSS scores in all the domains at 6 months from baseline between the two groups (p<0.05). In our series, there were no TEAEs, ADRs, and any other complications.
Conclusion
Intra-articular injections of HA combined with PDRN can also be considered in the treatment of knee osteoarthritis. However, further large-scale and multi-center studies are required to demonstrate the potential of the proposed combination.

Citations

Citations to this article as recorded by  
  • Emerging wound-healing injectable polydeoxyribonucleotide: potential as a prohibited doping method and its simple detection via CRISPR/Cas12a system
    Joon-Yeop Yi, Sanghwa Park, Minyoung Kim, Yujin Jeong, HyunA Shin, Yeojeong Cho, Mijin Jeon, Min-Kyu Oh, Changmin Sung
    International Journal of Biological Macromolecules.2025; 309: 142999.     CrossRef
  • Polydeoxyribonucleotide as a Regenerative Agent in Dermatology and Wound Healing: Mechanisms, Clinical Applications, and Safety
    Gi Young Park, Byeong-Churl Jang
    Keimyung Medical Journal.2025; 44(1): 9.     CrossRef
  • Points to ponder on the role of polynucleotides in regenerative and aesthetic medicine: a systematic review
    William Richard Webb, Eqram Rahman, Parinitha Rao, Hany Niamey Abu-Farsakh, Nanze Yu, Patricia E. Garcia, Sotirios Ioannidis, Karim Sayed, Elias Tam, Wolfgang G. Philipp-Dormston, Mohammad Najlah, Zakia Rahman, Jean D. A. Carruthers, Ash Mosahebi
    European Journal of Plastic Surgery.2024;[Epub]     CrossRef
  • An injectable hyaluronic acid-Polydeoxyribonucleotides (HA-PDRN) crosslinked hydrogel as a dermal filler
    Guo jiahong, Fang wei, Wang feifei
    European Polymer Journal.2024; 219: 113395.     CrossRef
  • Recent advances on polydeoxyribonucleotide extraction and its novel application in cosmeceuticals
    Thi Hanh Nguyen, San-Lang Wang, Van Bon Nguyen
    International Journal of Biological Macromolecules.2024; 282: 137051.     CrossRef
  • Injectable “Skin Boosters” in Aging Skin Rejuvenation: A Current Overview
    Nark-Kyoung Rho, Hyun-Seok Kim, Soo-Young Kim, Won Lee
    Archives of Plastic Surgery.2024; 51(06): 528.     CrossRef
  • Clinical Updates in Polydeoxyribonucleotide Injection
    Tae-Yeong Kim, Yong-Tae Kim, Jung-Taek Hwang
    Journal of the Korean Orthopaedic Association.2024; 59(6): 386.     CrossRef
  • Pseudoseptic Reaction to an Intra-Articular Polydeoxyribonucleotide Injection into the Ankle: A Case Report
    Seungcheol Yu, Hangaram Kim, Youngwoong Choi, Jeongsoo Kim
    International journal of Pain.2024; 15(2): 106.     CrossRef
  • Intra-articular injections of polynucleotides for joint preconditioning before the injections of bionic cross-link hyaluronic acid. Case report
    Irina S. Svintsitskaya, Konstantin Yu. Volkov, Aleksei Chetaikin Storm
    Terapevticheskii arkhiv.2024; 96(12): 1238.     CrossRef
  • Therapeutic effects of polydeoxyribonucleotide in an in vitro neuronal model of ischemia/reperfusion injury
    Seongmoon Jo, Ahreum Baek, Yoonhee Cho, Sung Hoon Kim, Dawoon Baek, Jihye Hwang, Sung-Rae Cho, Hyun Jung Kim
    Scientific Reports.2023;[Epub]     CrossRef
  • Skin boosters – The upcoming boom in cosmetic dermatology for healthy skin
    Maya Vedamurthy, Vaishnavi Duvvuru, Vijaya Lakshmi Chelikani
    Cosmoderma.2023; 3: 82.     CrossRef
  • Role and Effectiveness of Intra-articular Injection of Hyaluronic Acid in the Treatment of Knee Osteoarthritis: A Systematic Review
    Sumant Chavda, Syed Arman Rabbani, Tarun Wadhwa
    Cureus.2022;[Epub]     CrossRef
  • Polydeoxyribonucleotide: A promising skin anti-aging agent
    Aawrish Khan, Guobao Wang, Feng Zhou, Lunli Gong, Jun Zhang, Lili Qi, Haiyan Cui
    Chinese Journal of Plastic and Reconstructive Surgery.2022; 4(4): 187.     CrossRef
  • Adenosine A2A receptor agonist polydeoxyribonucleotide ameliorates short-term memory impairment by suppressing cerebral ischemia-induced inflammation via MAPK pathway
    Il-Gyu Ko, Jun-Jang Jin, Lakkyong Hwang, Sang-Hoon Kim, Chang-Ju Kim, Jung Won Jeon, Jun-Young Chung, Jin Hee Han, Giuseppe Pignataro
    PLOS ONE.2021; 16(3): e0248689.     CrossRef
  • Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering
    Tae-Hee Kim, Seong-Yeong Heo, Gun-Woo Oh, Soo-Jin Heo, Won-Kyo Jung
    Marine Drugs.2021; 19(6): 296.     CrossRef
  • Mesenchymal Stem Cells Use in the Treatment of Tendon Disorders: A Systematic Review and Meta-Analysis of Prospective Clinical Studies
    Woo Sup Cho, Sun Gun Chung, Won Kim, Chris H. Jo, Shi-Uk Lee, Sang Yoon Lee
    Annals of Rehabilitation Medicine.2021; 45(4): 274.     CrossRef
  • Viscosupplementation in the Therapy for Osteoarthritic Knee
    Junghyun Park, Hue Jung Park, Min Cheol Rho, Jin Joo
    Applied Sciences.2021; 11(24): 11621.     CrossRef
  • A Comprehensive Review of Viscosupplementation in Osteoarthritis of the Knee
    Jacquelin Peck, Annabel Slovek, Paulo Miro, Neeraj Vij, Blake Traube, Christopher Lee, Amnon A. Berger, Hisham Kassem, Alan D. Kaye, William F. Sherman, Alaa Abd-Elsayed
    Orthopedic Reviews.2021;[Epub]     CrossRef
  • Polydeoxyribonucleotide Regulation of Inflammation
    Maria Teresa Colangelo, Carlo Galli, Stefano Guizzardi
    Advances in Wound Care.2020; 9(10): 576.     CrossRef
  • The efficacy and safety of polydeoxyribonucleotide for the treatment of knee osteoarthritis
    Man Soo Kim, Ryu Kyoung Cho, Yong In
    Medicine.2019; 98(39): e17386.     CrossRef
  • 12,698 View
  • 489 Download
  • 15 Web of Science
  • 20 Crossref
Needle Entry Angle to Prevent Carotid Sheath Injury for Fluoroscopy-Guided Cervical Transforaminal Epidural Steroid Injection
Jaewoo Choi, Doo Hoe Ha, Shinyoung Kwon, Youngsu Jung, Junghoon Yu, MinYoung Kim, Kyunghoon Min
Ann Rehabil Med 2018;42(6):814-821.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.814
Objective
To suggest rotation angles of fluoroscopy that can bypass the carotid sheath according to vertebral levels for cervical transforaminal epidural steroid injection (TFESI).
Methods
Patients who underwent cervical spine magnetic resonance imaging (MRI) from January 2009 to October 2017 were analyzed. In axial sections of cervical spine MRI, three angles to the vertical line (α, angle not to insult carotid sheath; β, angle for the conventional TFESI; γ, angle not to penetrate carotid artery) were measured.
Results
Alpha (α) angles tended to increase for upper cervical levels (53.3° in C6-7, 65.2° in C5-6, 75.3° in C4-5, 82.3° in C3-4). Beta (β) angles for conventional TFESI showed a constant value of 45° to 47° (47.5° in C6-7, 47.4° in C5-6, 45.7° in C4-5, 45.0° in C3-4). Gamma (γ) angles increased at higher cervical levels as did α angles (25.2° in C6-7, 33.6° in C5-6, 43.0° in C4-5, 56.2° in C3-4).
Conclusion
The risk of causing injury by penetrating major vessels in the carotid sheath tends to increase at upper cervical levels. Therefore, prior to cervical TFESI, measuring the angle is necessary to avoid carotid vessels in the axial section of CT or MRI, thus contributing to a safer procedure.

Citations

Citations to this article as recorded by  
  • A Randomized Comparative Trial of Targeted Steroid Injection via Epidural Catheter vs Standard Transforaminal Epidural Injection for the Treatment of Unilateral Cervical Radicular Pain: Six-Month Results
    Zachary L McCormick, Aaron Conger, Beau P Sperry, Masaru Teramoto, Russell Petersen, Fabio Salazar, Shellie Cunningham, A Michael Henrie, Erica Bisson, Richard Kendall
    Pain Medicine.2020; 21(10): 2077.     CrossRef
  • 9,985 View
  • 157 Download
  • 1 Web of Science
  • 1 Crossref
Extracorporeal Shock Wave Therapy Versus Trigger Point Injection in the Treatment of Myofascial Pain Syndrome in the Quadratus Lumborum
Jin Oh Hong, Joon Sang Park, Dae Geun Jeon, Wang Hyeon Yoon, Jung Hyun Park
Ann Rehabil Med 2017;41(4):582-588.   Published online August 31, 2017
DOI: https://doi.org/10.5535/arm.2017.41.4.582
Objective

To compare the effectiveness of extracorporeal shock wave therapy (ESWT) and trigger point injection (TPI) for the treatment of myofascial pain syndrome in the quadratus lumborum.

Methods

In a retrospective study at our institute, 30 patients with myofascial pain syndrome in the quadratus lumborum were assigned to ESWT or TPI groups. We assessed ESWT and TPI treatment according to their affects on pain relief and disability improvement. The outcome measures for the pain assessment were a visual analogue scale score and pain pressure threshold. The outcome measures for the disability assessment were Oswestry Disability Index, Roles and Maudsley, and Quebec Back Pain Disability Scale scores.

Results

Both groups demonstrated statistically significant improvements in pain and disability measures after treatment. However, in comparing the treatments, we found ESWT to be more effective than TPI for pain relief. There were no statistically significant differences between the groups with respect to disability.

Conclusion

Compared to TPI, ESWT showed superior results for pain relief. Thus, we consider ESWT as an effective treatment for myofascial pain syndrome in the quadratus lumborum.

Citations

Citations to this article as recorded by  
  • Myofascial Pain Syndrome: A Comprehensive Systematic Literature Review on Diagnostic Approaches, Treatment Modalities and Recent Advances
    Anjani Kumar, Sanjay Kumar Pandey, Sanyal Kumar, Amit Kumar Mallik, Debasish Jena
    Indian Journal of Physical Medicine and Rehabilitation.2025; 35(2): 59.     CrossRef
  • Extracorporeal ShockWave Treatment vs. mesotherapy in the treatment of myofascial syndromes: a clinical trial
    Dalila Scaturro, Domenico Migliorino, Lorenza Lauricella, Francesco Quartararo, Noemi Calabrese, Sofia Tomasello, Michele Vecchio, Giulia Letizia Mauro
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Effect of Quadratus Lumborum Block in Patients With Acute-Subacute Unilateral Lumbar Strain
    Emine Yıldırım Uslu
    Cureus.2024;[Epub]     CrossRef
  • Focused extracorporeal shockwave therapy for the treatment of low back pain: a systematic review
    Dilyan Ferdinandov
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Effect of Extracorporeal Shock Wave on Upper Trapezius Trigger Points in Patients With Cervicogenic Headache
    Radwa F. Hammam, Ahmed M. Alshimy, Omar M. Elabd, Aliaa M. Elabd
    American Journal of Physical Medicine & Rehabilitation.2024; 103(11): 1000.     CrossRef
  • Efficacy and tolerability of extracorporeal shock wave therapy in patients with plantar fasciopathy: a systematic review with meta-analysis and meta-regression
    Lorenzo LIPPI, Arianna FOLLI, Stefano MOALLI, Alessio TURCO, Antonio AMMENDOLIA, Alessandro de SIRE, Marco INVERNIZZI
    European Journal of Physical and Rehabilitation Medicine.2024;[Epub]     CrossRef
  • The Use and Benefits of Focused Shockwaves for the Diagnosis of Myofascial Pain Syndrome by Examining Myofascial Trigger Points in Low Back Pain
    Hannes Müller-Ehrenberg, Federico Giordani, Alessandra Müller-Ehrenberg, Richard Stange
    Biomedicines.2024; 12(12): 2909.     CrossRef
  • Efficacy of ultrasound-guided infiltration with levobupivacaine and triamcinolone for myofascial pain syndrome of the quadratus lumborum: a retrospective observational study
    Anabela Barreto Silva, Nuno Malheiro, Belinda Oliveira, Diamantino Pereira, Filipe Antunes, Joana Borges, Ana Cristina Cunha
    Brazilian Journal of Anesthesiology (English Edition).2023; 73(6): 718.     CrossRef
  • Shock waves as treatment of mouse myofascial trigger points
    Pol Monclús, Marc Bosque, Ramón Margalef, M. Teresa Colomina, Francisco J. Valderrama‐Canales, Laia Just, Manel M. Santafé
    Pain Practice.2023; 23(7): 724.     CrossRef
  • Myofascial points treatment with focused extracorporeal shock wave therapy (f-ESWT) for plantar fasciitis: an open label randomized clinical trial
    Lucrezia TOGNOLO, Federico GIORDANI, Carlo BIZ, Andrea BERNINI, Pietro RUGGIERI, Carla STECCO, Anna C. FRIGO, Stefano MASIERO
    European Journal of Physical and Rehabilitation Medicine.2022;[Epub]     CrossRef
  • Efficacy and Effectiveness of Extracorporeal Shockwave Therapy in Patients with Myofascial Pain or Fibromyalgia: A Scoping Review
    Marco Paoletta, Antimo Moretti, Sara Liguori, Giuseppe Toro, Francesca Gimigliano, Giovanni Iolascon
    Medicina.2022; 58(8): 1014.     CrossRef
  • Immediate effect of shock wave versus muscle energy technique in cases of quadratus lumborum myofascial pain
    Hessa Al Shehhi, Mouza Lootah, Ibrahim Moustafa, Tamer Shousha
    Fizjoterapia Polska.2022; 22(4): 148.     CrossRef
  • Combined Effects of Extracorporeal Shockwave Therapy and Integrated Neuromuscular Inhibition on Myofascial Trigger Points of Upper Trapezius: A Randomized Controlled Trial
    Dina Al-Amir Mohamed, Ragia Mohamed Kamal, Manal Mohamed Gaber, Yasser M. Aneis
    Annals of Rehabilitation Medicine.2021; 45(4): 284.     CrossRef
  • Comparison of efficacy of corticosteroid injection versus extracorporeal shock wave therapy on inferior trigger points in the quadratus lumborum muscle: a randomized clinical trial
    Bina Eftekharsadat, Negar Fasaie, Dina Golalizadeh, Arash Babaei-Ghazani, Fatemeh Jahanjou, Yashar Eslampoor, Neda Dolatkhah
    BMC Musculoskeletal Disorders.2020;[Epub]     CrossRef
  • Enhanced Spinal Therapy: Extracorporeal Shock Wave Therapy for the Spine
    Brian Fiani, Cyrus Davati, Daniel W Griepp, Jason Lee, Elisabeth Pennington, Christina M Moawad
    Cureus.2020;[Epub]     CrossRef
  • Efficacy of Extracorporeal Shockwave Therapy on Cervical Myofascial Pain Following Neck Dissection Surgery: A Randomized Controlled Trial
    FatmaAlzahraa Hassan Kamel, Maged Basha, Ashwag Alsharidah, Islam Mohamed Hewidy, Mohamed Ezzat, Nancy Hassan Aboelnour
    Annals of Rehabilitation Medicine.2020; 44(5): 393.     CrossRef
  • Efficacy of Extracorporeal Shock Wave Therapy in Neck and Shoulder Pain Syndrome
    Joon Yub Kim, Jae Yoon Kim, Jong Pil Yoon, Seok Won Chung, Dong-Hyun Kim, Yoo-Sun Won
    The Korean Journal of Sports Medicine.2020; 38(4): 208.     CrossRef
  • The effect of core stabilization exercises and shock wave therapy in patients with radiculopathy
    J. Bubelis
    Neurologijos seminarai.2018; 22(2(76)): 123.     CrossRef
  • 8,289 View
  • 235 Download
  • 20 Web of Science
  • 18 Crossref
Characteristics of Myofascial Pain Syndrome of the Infraspinatus Muscle
Junbeom Kwon, Hyoung Seop Kim, Won Hyuk Chang, Chunung Park, Sang Chul Lee
Ann Rehabil Med 2017;41(4):573-581.   Published online August 31, 2017
DOI: https://doi.org/10.5535/arm.2017.41.4.573
Objective

To report the characteristics of myofascial trigger points (MTrPs) in the infraspinatus muscle and evaluate the therapeutic effect of trigger-point injections.

Methods

Medical records of 297 patients (221 women; age, 53.9±11.3 years) with MTrPs in the infraspinatus muscle were reviewed retrospectively. Because there were 83 patients with MTrPs in both infraspinatus muscles, the characteristics of total 380 infraspinatus muscles with MTrPs (214 one side, 83 both sides) were investigated. Specific characteristics collected included chief complaint area, referred pain pattern, the number of local twitch responses, and distribution of MTrPs in the muscle. For statistical analysis, the paired t-test was used to compare a visual analogue scale (VAS) before and 2 weeks after the first injection.

Results

The most common chief complaint area of MTrPs in the infraspinatus muscle was the scapular area. The most common pattern of referred pain was the anterolateral aspect of the arm (above the elbow). Active MTrPs were multiple rather than single in the infraspinatus muscle. MTrPs were frequently in the center of the muscle. Trigger-point injection of the infraspinatus muscle significantly decreased the pain intensity. Mean VAS score decreased significantly after the first injection compared to the baseline (7.11 vs. 3.74; p<0.001).

Conclusion

Characteristics of MTrPs and the therapeutic effects of trigger-point injections of the infraspinatus muscle were assessed. These findings could provide clinicians with useful information in diagnosing and treating myofascial pain syndrome of the infraspinatus muscle.

Citations

Citations to this article as recorded by  
  • Blood Flow of the Infraspinatus Muscle in Individuals With and Without Shoulder Pain and Myofascial Trigger Points
    Jace Brown, Gary Kearns, Emily Hedges, Samantha Samaniego, Sharon Wang‐Price
    Journal of Ultrasound in Medicine.2025; 44(1): 127.     CrossRef
  • The effects of dry needling on muscle blood flow of the infraspinatus muscle in individuals with shoulder pain - a randomized clinical trial
    Jace Brown, Gary Kearns, Kelli Brizzolara, Mark Weber, Sharon Wang-Price
    Journal of Manual & Manipulative Therapy.2025; : 1.     CrossRef
  • Sonoanatomy and an ultrasound scanning protocol of the intramuscular innervation pattern of the infraspinatus muscle
    Hyung-Jin Lee, Ji-Hyun Lee, Kyu-Ho Yi, Hee-Jin Kim
    Regional Anesthesia & Pain Medicine.2023; 48(4): 175.     CrossRef
  • Anatomical analysis of the motor endplate zones of the suprascapular nerve to the infraspinatus muscle and its clinical significance in managing pain disorder
    Hyung‐Jin Lee, Ji‐Hyun Lee, Kyu‐Ho Yi, Hee‐Jin Kim
    Journal of Anatomy.2023; 243(3): 467.     CrossRef
  • Inter- and intra-rater-reliability of a clinical framework for spine-related neck-arm pain
    C. Kapitza, K. Luedtke, M. Komenda, M. Kiefhaber, A.B. Schmid, N. Ballenberger, B. Tampin
    Musculoskeletal Science and Practice.2023; 67: 102853.     CrossRef
  • The Clinical Results of Radial and Focused Extracorporeal Shockwave Therapy on Periscapular Myofascial Pain Syndrome
    Jaeman Lee, Cheungsoo Ha, Tae-Keun Ahn
    Journal of the Korean Orthopaedic Association.2022; 57(2): 122.     CrossRef
  • Change in muscle hardness after trigger point injection and physiotherapy for myofascial pain syndrome
    Akiko Okada-Ogawa, Naohiko Sekine, Kosuke Watanabe, Ryutaro Kohashi, Sayaka Asano, Koich Iwata, Yoshiki Imamura
    Journal of Oral Science.2019; 61(1): 36.     CrossRef
  • 7,970 View
  • 187 Download
  • 6 Web of Science
  • 7 Crossref
Contrast Spread in the Superoposterior Approach of Transforaminal Epidural Steroid Injections for Lumbosacral Radiculopathy
Young Cheol Jeong, Chung Ho Lee, Seok Kang, Joon Shik Yoon
Ann Rehabil Med 2017;41(3):413-420.   Published online June 29, 2017
DOI: https://doi.org/10.5535/arm.2017.41.3.413
Objective

To observe the contrast spread in superoposterior transforaminal epidural steroid injection (SP TFESI) and investigate the correlation between spread patterns and efficacy.

Methods

Thirty-one patients with lumbosacral radiculopathy underwent single-level TFESI under fluoroscopy. The final needle tip position was targeted toward the SP quadrant of the intervertebral foramen. To observe the spread, 1 mL of contrast material was injected, followed by a steroid injection. The contrast spread was graded anteroposteriorly and vertically in the epidural space. The effect of SP TFESI was evaluated by proportional pain score reduction.

Results

Levels injected were L4-5 (n=20) and L5-S1 (n=11). Seventeen cases were lateral, and 14 were central herniated disc (HD). Baseline mean visual analog scale score was 6.23. Contrast dispersed dorsally in all the cases, and 45.2% cases showed a concurrent ventral spread. The proportion of the pain reduction after 2 weeks showed no difference between the two groups. In vertical spreading analysis, mean cephalic/caudal grades were 1.40/1.55 at L4-5 level and 1.73/1.64 at L5-S1 level. The HD location had no effect on contrast dispersion.

Conclusion

In SP TFESI, ventral contrast spread did not guarantee a better effect; however, the extent of cephalic flow in ventral expansion group correlated with the proportion of pain reduction.

Citations

Citations to this article as recorded by  
  • Perfusion pressure as a determinant of respiratory function outcomes in unilateral biportal lumbar endoscopic procedures
    Liang Zhang, Han Zheng, Yan Fu, Wenbo Li, Jianlong Lang, Yi Wang, Weibin Ren
    Frontiers in Pharmacology.2025;[Epub]     CrossRef
  • Accurate location and minimally invasive treatment of lumbar lateral recess stenosis with combined SNRB and PTED
    Bing Yue, Fang Shen, Zhi-Fang Ye, Ze-Hao Wang, Hui-Lin Yang, Guo-Qiang Jiang
    Journal of International Medical Research.2020;[Epub]     CrossRef
  • Extraforaminal Cervical Selective Nerve Root Block‐Description of a Posterolateral Approach With Cone Beam–Based CT Guidance
    Shawn Reddy, Jiang Wu
    Pain Practice.2020; 20(8): 919.     CrossRef
  • CT-guided transforaminal epidural steroid injections: do needle position and degree of foraminal stenosis affect the pattern of epidural flow?
    Nityanand Miskin, Glenn C. Gaviola, Varand Ghazikhanian, Jacob C. Mandell
    Skeletal Radiology.2018; 47(12): 1615.     CrossRef
  • 11,497 View
  • 95 Download
  • 4 Web of Science
  • 4 Crossref
Ultrasonography Evaluation of Vulnerable Vessels Around Cervical Nerve Roots During Selective Cervical Nerve Root Block
Hoon Hoon Lee, Donghwi Park, Yoongul Oh, Ju Seok Ryu
Ann Rehabil Med 2017;41(1):66-71.   Published online February 28, 2017
DOI: https://doi.org/10.5535/arm.2017.41.1.66
Objective

To evaluate the prevalence of vulnerable blood vessels around cervical nerve roots before cervical nerve root block in the clinical setting.

Methods

This retrospective study included 74 patients with cervical radiculopathy who received an ultrasonography-guided nerve block at an outpatient clinic from July 2012 to July 2014. Before actual injection of the steroid was performed, we evaluated the vulnerable blood vessels around each C5, C6, and C7 nerve root of each patient's painful side, with Doppler ultrasound.

Results

Out of 74 cases, the C5 level had 2 blood vessels (2.7%), the C6 level had 4 blood vessels (5.45%), and the C7 level had 6 blood vessels (8.11%) close to each targeted nerve root. Moreover, the C5 level had 2 blood vessels (2.7%), the C6 level 5 blood vessels (6.75%), and the C7 level had 4 blood vessels (5.45%) at the site of an imaginary needle's projected pathway to the targeted nerve root, as revealed by axial transverse ultrasound imaging with color Doppler imaging. In total, the C5 level had 4 blood vessels (5.45%), the C6 level 9 blood vessels (12.16%), and the C7 level 10 had blood vessels (13.51%) either at the targeted nerve root or at the site of the imaginary needle's projected pathway to the targeted nerve root. There was an unneglectable prevalence of vulnerable blood vessels either at the targeted nerve root or at the site of the needle' projected pathway to the nerve root. Also, it shows a higher prevalence of vulnerable blood vessels either at the targeted nerve root or at the site of an imaginary needle's projected pathway to the nerve root as the spinal nerve root level gets lower.

Conclusion

To prevent unexpected critical complications involving vulnerable blood vessel injury during cervical nerve root block, it is recommended to routinely evaluate for the presence of vulnerable blood vessels around each cervical nerve root using Doppler ultrasound imaging before the cervical nerve root block, especially for the lower cervical nerve root level.

Citations

Citations to this article as recorded by  
  • Ultrasound-Guided Selective Cervical Root Block in Spondylotic Radiculopathy: Advantages and Safety
    Dong Gyu Lee
    Clinical Pain.2023; 22(2): 61.     CrossRef
  • A prospective randomized comparison of the efficacy of standard antiviral therapy versus ultrasound-guided thoracic paravertebral block for acute herpes zoster
    Yingchao Ma, Bingsi Li, Lei Sun, Xin He, Shuang Wu, Fan Shi, Li Niu
    Annals of Medicine.2022; 54(1): 369.     CrossRef
  • Diagnosis and Treatment of Cervical Spondylotic Radiculopathy Using Selective Nerve Root Block (SNRB): Where are We Now?
    Dongfang Yang, Lichen Xu, Yutong Hu, Weibing Xu
    Pain and Therapy.2022; 11(2): 341.     CrossRef
  • Remnant Tumor Margin as Predictive Factor for Its Growth After Incomplete Resection of Cervical Dumbbell-Shaped Schwannomas
    Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Satoshi Suzuki, Satoshi Nori, Eijiro Okada, Mitsuru Yagi, Morio Matsumoto, Masaya Nakamura, Kota Watanabe
    Neurospine.2022; 19(1): 32.     CrossRef
  • An open-label non-inferiority randomized trail comparing the effectiveness and safety of ultrasound-guided selective cervical nerve root block and fluoroscopy-guided cervical transforaminal epidural block for cervical radiculopathy
    Xiaohong Cui, Di Zhang, Yongming Zhao, Yongsheng Song, Liangliang He, Jian Zhang
    Annals of Medicine.2022; 54(1): 2669.     CrossRef
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    Reza Ehsanian, Byron J Schneider, David J Kennedy, Eugene Koshkin
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    Hazem Adel Ashmawi, André Marques Mansano
    Revista Paulista de Reumatologia.2021; (2021 abr-j): 61.     CrossRef
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    Reza Ehsanian, David J. Kennedy, Byron Schneider
    Current Physical Medicine and Rehabilitation Reports.2019; 7(4): 386.     CrossRef
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The Prognostic Value of Enhanced-MRI and Fluoroscopic Factors for Predicting the Effects of Transforaminal Steroid Injections on Lumbosacral Radiating Pain
Yun Suk Jung, Jee Hyun Suh, Ha Young Kim, Kyunghoon Min, Yoongul Oh, Donghwi Park, Ju Seok Ryu
Ann Rehabil Med 2016;40(6):1071-1081.   Published online December 30, 2016
DOI: https://doi.org/10.5535/arm.2016.40.6.1071
Objective

To investigate the predictive value of enhanced-magnetic resonance imaging (MRI) and fluoroscopic factors regarding the effects of transforaminal epidural steroid injections (TFESIs) in low back pain (LBP) patients with lumbosacral radiating pain.

Methods

A total of 51 patients who had LBP with radiating pain were recruited between January 2011 and December 2012. The patient data were classified into the two groups ‘favorable group’ and ‘non-favorable group’ after 2 weeks of follow-up results. The favorable group was defined as those with a 50%, or more, reduction of pain severity according to the visual analogue scale (VAS) for back or leg pain. The clinical and radiological data were collected for univariate and multivariate analyses to determine the predictors of the effectiveness of TFESIs between the two groups.

Results

According to the back or the leg favorable-VAS group, the univariate analysis revealed that the corticosteroid approach for the enhanced nerve root, the proportion of the proximal flow, and the contrast dispersion of epidurography are respectively statistically significant relative to the other factors. Lastly, the multiple logistic regression analysis showed a significant association between the corticosteroid approach and the enhanced nerve root in the favorable VAS group.

Conclusion

Among the variables, MRI showed that the corticosteroid approach for the enhanced target root is the most important prognostic factor in the predicting of the clinical parameters of the favorable TFESIs group.

Citations

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Case Report

Acute Paraplegia After Lumbar Steroid Injection in Patients With Spinal Dural Arteriovenous Fistulas: Case Reports
Sunwoong Kim, Yuseong Choi, Jinyoung Park, Duk Hyun Sung
Ann Rehabil Med 2016;40(5):949-954.   Published online October 31, 2016
DOI: https://doi.org/10.5535/arm.2016.40.5.949

Spinal dural arteriovenous fistulas (SDAVFs) are the most common type of spinal vascular malformations. However, SDAVFs are still underdiagnosed entities because their clinical symptoms are usually non-specific, as they include low back pain or radiating pain to the limb. There have been several reports of acute paraplegia after lumbar epidural steroid injections in patients with SDAVFs. We present 4 patients with SDAVFs who received lumbar steroid injection. Among the 4 cases, acute paraplegia developed in 2 cases that received a larger volume of injectate than the other cases. Thus, we are suggesting that the volume of injectate may be a contributing factor for acute paraplegia after lumbar steroid injection in patients with SDAVFs.

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Original Articles

Comparison of the Effects of Ultrasound-Guided Interfascial Pulsed Radiofrequency and Ultrasound-Guided Interfascial Injection on Myofascial Pain Syndrome of the Gastrocnemius
So Min Park, Yun Woo Cho, Sang Ho Ahn, Dong Gyu Lee, Hee Kyung Cho, Sung Yup Kim
Ann Rehabil Med 2016;40(5):885-892.   Published online October 31, 2016
DOI: https://doi.org/10.5535/arm.2016.40.5.885
Objective

To investigate the comparative treatment effects of ultrasound-guided pulsed radiofrequency treatment (UG-PRF) in the gastrocnemius interfascial space and ultrasound-guided interfascial injection (UG-INJ) on myofascial pain syndrome.

Methods

Forty consecutive patients with myofascial pain syndrome of the gastrocnemius were enrolled and were allocated to one of the two groups. Twenty patients were treated by UG-PRF delivered to the gastrocnemius interfascial space (UG-PRF group) and the other 20 patients were treated by interfascial injection (UG-INJ group). The primary outcome measure was the numeric rating score (NRS) for pain on pressing the tender point in the gastrocnemius, and the secondary outcome measure was health-related quality of life as determined by the Short Form-36 questionnaire (SF-36). NRSs were obtained at the first visit, immediately after treatment, and at 2 and 4 weeks post-treatment, and physical component summary scores (PCS) and mental component summary scores (MCS) of the SF-36 questionnaire were measured at the first visit and at 4 weeks post-treatment.

Results

Immediately after treatments, mean NRS in the UG-PRF group was significantly higher than that in the UG-INJ group (p<0.0001). However, at 2 and 4 weeks post-treatment, the mean NRS was significantly lower in the UG-PRF group (both p<0.0001). Similarly, at 4 weeks post-treatment, mean PCS and MCS were significantly higher in the UG-PRF group (p<0.0001 and p=0.002, respectively).

Conclusion

Based on these results, the authors conclude that ultrasound-guided gastrocnemius interfascial PRF provides an attractive treatment for myofascial pain syndrome of the gastrocnemius.

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  • Study on the Effectiveness of Ultrasound-guided Pulsed Radiofrequency Therapy for Shoulder Pain Caused by Trigger Points
    Wei Shen, Nan-hai Xie, Xin-yu Cong, Yong-jun Zheng
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    Damla Yürük, Ömer Taylan Akkaya, Özgür Emre Polat, Hüseyin Alp Alptekin
    Journal of Ultrasound in Medicine.2022; 41(1): 185.     CrossRef
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    Min Cheol Chang, Seoyon Yang
    World Journal of Clinical Cases.2022; 10(22): 7720.     CrossRef
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    Magdalena Kocot-Kępska, Maksymilian Hanarz, Karolina Pająk-Wyżga, Gabriela Mruk, Anna Przeklasa-Muszyńska
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    Min Cheol Chang, Dong Gyu Lee
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    Gang Wang, Xinglin Wang, Qian Gao, Ming Zhou, Ning Wang
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    Sarah Razaq, Murat Kara, Bayram Kaymak, Iskender Öner, Ömer Ozkan, Levent Özçakar
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    MinCheol Chang, YunWoo Cho
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    Ik Tae Cho, Yun Woo Cho, Sang Gyu Kwak, Min Cheol Chang
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Effect of Intra-articular Hyaluronic Acid Injection on Hemiplegic Shoulder Pain After Stroke
Myung Hun Jang, Chang-Hyung Lee, Yong-Il Shin, Soo-Yeon Kim, Sung Chul Huh
Ann Rehabil Med 2016;40(5):835-844.   Published online October 31, 2016
DOI: https://doi.org/10.5535/arm.2016.40.5.835
Objective

To evaluate the efficacy of intra-articular hyaluronic acid (IAHA) injection for hemiplegic shoulder pain (HSP) after stroke.

Methods

Thirty-one patients with HSP and limited range of motion (ROM) without spasticity of upper extremity were recruited. All subjects were randomly allocated to group A (n=15) for three weekly IAHA injection or group B (n=16) for a single intra-articular steroid (IAS) injection. All injections were administered by an expert physician until the 8th week using a posterior ultrasonography-guided approach. Shoulder joint pain was measured using the Wong-Baker Scale (WBS), while passive ROM was measured in the supine position by an expert physician.

Results

There were no significant intergroup differences in WBS or ROM at the 8th week. Improvements in forward flexion and external rotation were observed from the 4th week in the IAHA group and the 8th week in the IAS group. Subjects experienced a statistically significant improvement in pain from the 1st week in the IAS and from the 8th week in IAHA group, respectively.

Conclusion

IAHA seems to have a less potent ability to reduce movement pain compared to steroid in the early period. However, there was no statistically significant intergroup difference in WBS and ROM improvements at the 8th week. IAHA might be a good alternative to steroid for managing HSP when the use of steroid is limited.

Citations

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    Aryoobarzan Rahmatian, Elham Bastani, Fariba Shokri, Ali Karbasfrushan
    Anesthesiology and Pain Medicine.2023;[Epub]     CrossRef
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    Hui-Min Xie, Ting-Ting Guo, Xuan Sun, Han-Xiao Ge, Xue-Dan Chen, Ke-Jia Zhao, Li-Ning Zhang
    Archives of Physical Medicine and Rehabilitation.2021; 102(9): 1775.     CrossRef
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    Yi-Hsiang Chiu, Ke-Vin Chang, Wei-Ting Wu, Po-Cheng Hsu, Levent Özçakar
    Pharmaceuticals.2021; 14(8): 788.     CrossRef
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    Eun-Mi Oh, Eun-Jung Lee
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    Min Cheol Chang
    International Journal of Neuroscience.2017; 127(11): 958.     CrossRef
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    Donghwi Park, Kwang Jae Yu, Ju Young Cho, Seung Beom Woo, Junu Park, Zeeihn Lee, Jong Min Kim
    Medicine.2017; 96(46): e8741.     CrossRef
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    Xiangnan Yuan, Zhiqiang Zhang, Jianjun Li
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Botulinum Toxin A Injection into the Subscapularis Muscle to Treat Intractable Hemiplegic Shoulder Pain
Jeong-Gue Choi, Joon-Ho Shin, Bo-Ra Kim
Ann Rehabil Med 2016;40(4):592-599.   Published online August 24, 2016
DOI: https://doi.org/10.5535/arm.2016.40.4.592
Objective

To evaluate the beneficial effect of botulinum toxin A (Botox) injection into the subscapularis muscle on intractable hemiplegic shoulder pain.

Methods

Six stroke patients with intractable hemiplegic shoulder pain were included. Botulinum toxin A was injected into the subscapularis muscle. Intractable hemiplegic shoulder pain was evaluated using an 11-point numerical rating scale. Pain-free range of motion was assessed for shoulder abduction and external rotation. The spasticity of the shoulder internal rotator was measured using the modified Ashworth scale. Assessments were carried out at baseline and at 1, 2, 4, and, if possible, 8 weeks.

Results

Intractable hemiplegic shoulder pain was improved (p=0.004) after botulinum toxin injection into the subscapularis muscle. Restricted shoulder abduction (p=0.003), external rotation (p=0.005), and spasticity of the shoulder internal rotator (p=0.005) were also improved. Improved hemiplegic shoulder pain was correlated with improved shoulder abduction (r=–1.0, p<0.001), external rotation (r=–1.0, p<0.001), and spasticity of the internal rotator (r=1.0, p<0.001).

Conclusion

Botulinum toxin A injection into the subscapularis muscle appears to be valuable in the management of intractable hemiplegic shoulder pain.

Citations

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    Praveen Kumar, Avgi Christodoulou, Michael Loizou
    Disability and Rehabilitation.2025; 47(7): 1677.     CrossRef
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    Peng Zheng, Yu Shi, Hang Qu, Meng lin Han, Zhi qiang Wang, Qing Zeng, Manxu Zheng, Tao Fan
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    Logeswaran Selvarajah, Mark Cresswell, Romain David, Paul Winston, Timothy Murray
    Journal of Ultrasound.2024; 27(4): 963.     CrossRef
  • Canadian Physicians’ Use of Intramuscular Botulinum Toxin Injections for Shoulder Spasticity: A National Cross-Sectional Survey
    Farris Kassam, Brendan Lim, Sadia Afroz, Ève Boissonnault, Rajiv Reebye, Heather Finlayson, Paul Winston
    Toxins.2023; 15(1): 58.     CrossRef
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    Pieter Struyf, Lisa Tedesco Triccas, Fabienne Schillebeeckx, Filip Struyf
    International Journal of Environmental Research and Public Health.2023; 20(4): 2797.     CrossRef
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    Jingjing Zhang, Huiwen Mao, Fang Gao, Yan Li, Yang Yang
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    Subhadeep Batabyal, Saumen Kumar De, Rathindra Nath Haldar
    INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH.2021; : 16.     CrossRef
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    Trutz Vogelsang, Jens Agneskirchner
    Arthroskopie.2021; 34(5): 390.     CrossRef
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    Botao Tan, Lang Jia
    Stroke.2021; 52(12): 3759.     CrossRef
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    Neurological Sciences.2020; 41(8): 2225.     CrossRef
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    Ke-Vin Chang, Yi-Hsiang Chiu, Wei-Ting Wu, Po-Cheng Hsu, Levent Özçakar
    Pain Management.2020; 10(6): 411.     CrossRef
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    Ian James Baguley, Hannah Louise Holman Barden, Emmanuel Jesulola, Melissa Therese Nott
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  • Ultrasound Visualization of Torsional Anatomic Changes From External Rotation of the Anterior Shoulder
    Jeffrey A. Strakowski, Faye Y. Chiou-Tan, Elizabeth G. Forrest, Uvieoghene O. Ughwanogho, Katherine H. Taber
    Journal of Computer Assisted Tomography.2019; 43(3): 519.     CrossRef
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    Jihye Park, Myung Eun Chung
    Toxins.2018; 10(6): 224.     CrossRef
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Phantom Study of a New Laser-Etched Needle for Improving Visibility During Ultrasonography-Guided Lumbar Medial Branch Access With Novices
Jung Wook Park, Min Woo Cheon, Min Hong Lee
Ann Rehabil Med 2016;40(4):575-582.   Published online August 24, 2016
DOI: https://doi.org/10.5535/arm.2016.40.4.575
Objective

To compare the visibility and procedural parameters between a standard spinal needle and a new laser-etched needle (LEN) in real-time ultrasonography guided lumbar medial branch access in a phantom of the lumbosacral spine.

Methods

We conducted a prospective single-blinded observational study at a rehabilitation medicine center. A new model of LEN was manufactured with a standard 22-gauge spinal needle and a laser etching machine. Thirty-two inexperienced polyclinic medical students performed ultrasonography-guided lumbar medial branch access using both a standard spinal needle and a LEN with scanning protocol. The outcomes included needle visibility score, needle elapsed time, first-pass success rate, and number of needle sticks.

Results

The LEN received significantly better visibility scores and shorter needle elapsed time compared to the standard spinal needle. First-pass success rate and the number of needle sticks were not significantly different between needles.

Conclusion

A new LEN is expected to offer better visibility and enable inexperienced users to perform an ultrasonography-guided lumbar medial branch block more quickly. However, further study of variables may be necessary for clinical application.

Citations

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    Adam Margalit, Henry Phalen, Cong Gao, Justin Ma, Krishna V. Suresh, Punya Jain, Amirhossein Farvardin, Russell H. Taylor, Mehran Armand, Akhil Chattre, Amit Jain
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    Ignacio Muro‐Fraguas, Ana Sainz‐García, Rodolfo Múgica‐Vidal, Elisa Sainz‐García, Ana González‐Marcos, Fernando Alba‐Elías
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    Caroline Harder Hovgesen, Jens E. Wilhjelm, Peter Vilmann, Evangelos Kalaitzakis
    Journal of Ultrasound in Medicine.2022; 41(2): 311.     CrossRef
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    Guntz Emmanuel, Pourveur Arnaud, Gouwy Jonathan, Renard Marie, Mocanu Iulia, Pather Sanjiva, Fils Jean-François, Vannieuwenhove Olivier
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    Paul Mignon, Philippe Poignet, Jocelyne Troccaz
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    Yi Li, Zhixi Li, Simon Ammanuel, Derrick Gillan, Vinil Shah
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Objective

To evaluate the feasibility of a new position (internal rotation in hanging) in ultrasonography, we compared the length of the glenohumeral joint space and the effectiveness of steroid injection with the hanging position and with the commonly used abdomen or cross position.

Methods

A prospective, randomized controlled trial was performed in 42 patients with adhesive capsulitis of shoulder. We used three arm positions for the posterior approach as follows: the patient's palm on thigh, other hand on abdomen (abdomen position); hand on patient's opposite shoulder (cross position); arm in hanging position with internal rotation of shoulder (hanging position). The order of shoulder position was randomized and blinded. Real-time ultrasonography-guided intra-articular steroid injection was performed by posterior approach at the first position in each patient. The Brief Pain Inventory (BPI), the Shoulder Pain and Disability Index (SPADI), and range of motion (ROM) were measured before steroid injection and 2 weeks after injection.

Results

The lengths of the joint space were 2.88±0.75, 2.93±0.89, and 2.82±0.79 mm in abdomen, cross, and hanging position respectively, with no significant difference among the three positions (p=0.429). Treatment efficacy was significantly improved in ROM, total BPI, and SPADI in all three positions (p<0.001). The changes in ROM for shoulder abduction were 23.6°±19.7°, 22.2°±20.9°, and 10.0°±7.8° in abdomen, cross, and hanging position, respectively. Changes in total BPI scores were 25.1±15.7, 23.6.±18.0, 11.6±6.1, and changes in total SPADI score were 35.0±14.2, 30.9±28.9, and 16.5±10.3 in abdomen, cross, and hanging position, respectively. There were no significant difference among the three positions for all parameters (p=0.194, p=0.121, and p=0.108, respectively.

Conclusion

For patients with adhesive capsulitis who cannot achieve or maintain abdomen or cross position, scanning and injection with the shoulder in internal rotation with hanging position may be a useful alternative.

Citations

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  • Effects of Transcatheter Arterial Embolization for Chronic Intractable Shoulder Pain: A Prospective Clinical Study
    Kun Yung Kim, Young-Min Han, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park, Yu Hui Won, Gi-Wook Kim, Tun-Chieh Chen
    International Journal of Clinical Practice.2025;[Epub]     CrossRef
  • Effect of Arm Position on Visualization of Target Zone for Posterior Glenohumeral Joint Injection
    James Kho, Ghassan Almeer, Christine Azzopardi, Ravneet Singh, Steven James, Rajesh Botchu
    Indian Journal of Musculoskeletal Radiology.2020; 2: 104.     CrossRef
  • Treatment of Adhesive Capsulitis of the Shoulder
    Lauren H. Redler, Elizabeth R. Dennis
    Journal of the American Academy of Orthopaedic Surgeons.2019; 27(12): e544.     CrossRef
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Survey of Botulinum Toxin Injections in Anticoagulated Patients: Korean Physiatrists' Preference in Controlling Anticoagulation Profile Prior to Intramuscular Injection
Yongjun Jang, Geun-Young Park, Jihye Park, Asayeon Choi, Soo Yeon Kim, Chris Boulias, Chetan P. Phadke, Farooq Ismail, Sun Im
Ann Rehabil Med 2016;40(2):279-287.   Published online April 25, 2016
DOI: https://doi.org/10.5535/arm.2016.40.2.279
Correction in: Ann Rehabil Med 2016;40(3):556
Objective

To evaluate Korean physiatrists' practice of performing intramuscular botulinum toxin injection in anticoagulated patients and to assess their preference in controlling the bleeding risk before injection.

Methods

As part of an international collaboration survey study, a questionnaire survey was administered to 100 Korean physiatrists. Physiatrists were asked about their level of experience with botulinum toxin injection, the safe international normalized ratio range in anticoagulated patients undergoing injection, their tendency for injecting into deep muscles, and their experience of bleeding complications.

Results

International normalized ratio <2.0 was perceived as an ideal range for performing Botulinum toxin injection by 41% of the respondents. Thirty-six respondents replied that the international normalized ratio should be lowered to sub-therapeutic levels before injection, and 18% of the respondents reported that anticoagulants should be intentionally withheld and discontinued prior to injection. In addition, 20%–30% of the respondents answered that they were uncertain whether they should perform the injection regardless of the international normalized ratio values. About 69% of the respondents replied that they did have any standardized protocols for performing botulinum toxin injection in patients using anticoagulants. Only 1 physiatrist replied that he had encountered a case of compartment syndrome.

Conclusion

In accordance with the lack of consensus in performing intramuscular botulinum toxin injection in anticoagulated patients, our survey shows a wide range of practices among many Korean physiatrists; they tend to avoid botulinum toxin injection in anticoagulated patients and are uncertain about how to approach these patients. The results of this study emphasize the need for formulating a proper international consensus on botulinum toxin injection management in anticoagulated patients.

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    María Muñoz, Jan Dommerholt, Sara Pérez-Palomares, Pablo Herrero, Sandra Calvo, Massimiliano Valeriani
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    Yeow Leng Tan, Tze Chao Wee
    PM&R.2021; 13(8): 880.     CrossRef
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  • Management of antithrombotics for intramuscular injection of botulinum toxin for spasticity. A survey of real-life practice in France
    Ozoua Ble, Djamel Bensmail, Dominic Pérennou, Bernard Parratte, Pierre-Alain Joseph, François-Constant Boyer, Hugues Michelon, Thibaud Lansaman, Jonathan Levy
    Annals of Physical and Rehabilitation Medicine.2021; 64(6): 101467.     CrossRef
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    Rozalina Dimitrova, Lynn James, Chengcheng Liu, Amelia Orejudos, Irina Yushmanova, Mitchell F. Brin
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    Jeffrey LaVallee, Regan Royer, Geoffrey Smith
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    Toxicon.2017; 138: 188.     CrossRef
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The Effect and Safety of Steroid Injection in Lumbar Spinal Stenosis: With or Without Local Anesthetics
Sung Hyuk Song, Gi Hyeong Ryu, Jin Woo Park, Ho Jun Lee, Ki Yeun Nam, Hyojun Kim, Seung Yeon Kim, Bum Sun Kwon
Ann Rehabil Med 2016;40(1):14-20.   Published online February 26, 2016
DOI: https://doi.org/10.5535/arm.2016.40.1.14
Objective

To compare the long-term effect and safety of an epidural steroid injection in spinal stenosis patients, with or without local anesthetics.

Methods

Twenty-nine patients diagnosed with spinal stenosis were included and randomly divided into two groups. Translaminar epidural and selective nerve root spinal injection procedures were performed using steroids mixed with local anesthetics or normal saline. The effects of spinal injection procedures were measured with visual analogue scale (VAS) and functional rate index (FRI). These measurements were performed before injection, at 1 month after injection and at 3 months after injection. The occurrence of side effects was investigated each time.

Results

The VAS and FRI scores were significantly reduced in both the local anesthetics group and normal saline group at 1 and 3 months after the injection. However, there was no significant difference in VAS and FRI score reduction between the two groups each time. Side effects are not noted in both groups.

Conclusion

The spinal injection procedures using steroids mixed either with local anesthetics or normal saline have an effect in reducing pain and improving functional activities. However, there was no significant difference between the two groups in relation to side effects and the long-term effects of pain and function.

Citations

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    Saher Saeed, Jan Boriesosdick, Arwed Michael, Nina Pauline Haag, Julian Schreck, Denise Schoenbeck, Matthias Michael Woeltjen, Julius Henning Niehoff, Christoph Moenninghoff, Jan Borggrefe, Jan Robert Kroeger
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    Sana Sadat Khoshnazar, Hamid Reza Farpour, Reza Shahriarirad
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    Piotr Godek, Kuba Ptaszkowski
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    Danny Zakria, James R. Patrinely, Anna K. Dewan, Sharon E. Albers, Lee E. Wheless, Aleta N. Simmons, Brian C. Drolet
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    Carlo Ammendolia, Corey Hofkirchner, Joshua Plener, André Bussières, Michael J Schneider, James J Young, Andrea D Furlan, Kent Stuber, Aksa Ahmed, Carol Cancelliere, Aleisha Adeboyejo, Joseph Ornelas
    BMJ Open.2022; 12(1): e057724.     CrossRef
  • Do steroid injections to the peripheral nerve increase perineural fibrosis? An animal experimental study
    Mustafa ÇELİKTAŞ, Semih Kivanc OLGUNER, Kivilcim ERDOGAN, Remzi ÇAYLAK, Kenan DAĞLIOĞLU
    Journal of Surgery and Medicine.2022; 6(2): 181.     CrossRef
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    Mi-Hyun Kim, K.M.D., Eun-Sang Park, Hyeon-Ho Hwang, Yeo-Gyeong Lee, Geum-Ju Song, Mi-Ri Kwon, Jun-Hyuk Kang
    Journal of Korean Medicine Rehabilitation.2021; 31(3): 1.     CrossRef
  • Short-Term Efficacy of Epidural Injection of Triamcinolone Through Translaminar Approach for the Treatment of Lumbar Canal Stenosis
    Saeed Sabbaghan, Elham Mirzamohammadi, Maryam Ameri Mahabadi, Farshad Nikouei, Farhad Rahbarian, Susan Ahmadichaboki, Samira Eftekhari, Maryam Zamankhani, Amir Aghaie Aghdam
    Anesthesiology and Pain Medicine.2020;[Epub]     CrossRef
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    Ariana M. Nelson, Geeta Nagpal
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    Franz Xaver Glocker
    Deutsches Ärzteblatt Online.2018;[Epub]     CrossRef
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Objective

To investigate the efficacy of percutaneous adhesiolysis (PA) compared to fluoroscopy (FL)-guided transforaminal epidural steroid injection (TFESI) in patients with radicular pain caused by lumbar foraminal spinal stenosis (LFSS) by assessing pain relief and functional improvement at 4 and 12 weeks post-procedure.

Methods

This retrospective study included 45 patients who underwent PA or FL-guided TFSEI for radicular pain caused by LFSS of at least 3 months' duration. Outcomes were assessed with the Oswestry Disability Index (ODI) and Verbal Numeric Pain Scale (VNS) before the procedure and at 4 and 12 weeks post-procedure. A successful outcome was defined by >50% improvement in the VNS score and >40% improvement in the ODI score.

Results

ODI and VNS scores improved 4 and 12 weeks post-procedure in both groups. Statistically significant differences between groups were observed in ODI and VNS at 12 weeks (p<0.05). The proportion of patients with successful outcomes was significantly different between the two groups only at the 12-week time point.

Conclusion

Our study suggests that PA is effective for pain reduction and functional improvement in patients with chronic radicular pain caused by LFSS. Therefore, PA can be considered for patients with previous ineffective responses to conservative treatment. Although PA seems to be more effective than TFEFI according to the results of our study, in order to fully elucidate the difference in effectiveness, a prospective study with a larger sample size is necessary.

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    Burak Erken, Ipek S. Edipoglu
    Neuromodulation: Technology at the Neural Interface.2024; 27(1): 135.     CrossRef
  • The Short-Term Outcome of Transforaminal Epidural Steroid Injection in Patients with Radicular Pain Due to Foraminal Stenosis from Lumbar Isthmic Spondylolisthesis
    Gyu-Sik Choi, Mathieu Boudier-Revéret, Min Cheol Chang
    Journal of Pain Research.2024; Volume 17: 519.     CrossRef
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    Archives of Physical Medicine and Rehabilitation.2024; 105(8): 1458.     CrossRef
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  • Changes in pain scores and walking distance after transforaminal epidural steroid injection in patients with lumbar foraminal spinal stenosis
    Minsoo Kim, Jiwon Bak, Daehun Goh, Jangho Bae, Kiyoung Shin, Hee-Jeong Son, Jin Huh, Seong-Sik Kang, Byeongmun Hwang
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    Dong Ah Shin, Yoo Jin Choo, Min Cheol Chang
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    Halil Cihan Kose, Omer Taylan Akkaya
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    Journal of Surgery and Medicine.2022; 6(2): 181.     CrossRef
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Case Report

Cervical Meningomyelitis After Lumbar Epidural Steroid Injection
Yujin Lee, Joon-Sung Kim, Ji Yeon Kim
Ann Rehabil Med 2015;39(3):504-507.   Published online June 30, 2015
DOI: https://doi.org/10.5535/arm.2015.39.3.504

Epidural steroid injections (ESI) are a common treatment for back pain management. ESI-related complications have increased with the growing number of procedures. We report a case of cervical meningomyelitis followed by multiple lumbar ESI. A 60-year-old male with diabetes mellitus presented to our hospital with severe neck pain. He had a history of multiple lumbar injections from a local pain clinic. After admission, high fever and elevated inflammatory values were detected. L-spine magnetic resonance imaging (MRI) revealed hematoma in the S1 epidural space. Antibiotic treatment began under the diagnosis of a lumbar epidural abscess. Despite the treatment, he started to complain of weakness in both lower extremities. Three days later, the weakness progressed to both upper extremities. C-spine MRI revealed cervical leptomeningeal enhancement in the medulla oblongata and cervical spinal cord. Removal of the epidural abscess was performed, but there was no neurological improvement.

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Original Articles

Clinical Implications of Real-Time Visualized Ultrasound-Guided Injection for the Treatment of Ulnar Neuropathy at the Elbow: A Pilot Study
Chang Kweon Choi, Hyun Seok Lee, Jae Yeoun Kwon, Won-Jae Lee
Ann Rehabil Med 2015;39(2):176-182.   Published online April 24, 2015
DOI: https://doi.org/10.5535/arm.2015.39.2.176
Objective

To investigate the feasibility of ultrasound (US)-guided steroid injection by in-plane approach for cubital tunnel syndrome (CuTS), based on symptomatic, morphologic and electrophysiological outcomes.

Methods

A total of 10 patients, who were clinically diagnosed as CuTS and confirmed by an electrodiagnostic study, participated in this study. US-guided injection into the cubital tunnel was performed with 40 mg triamcinolone and 2 mL of 1% lidocaine. Outcomes of the injections were evaluated at pre-injection, 1st week and 4th week after injection. Visual analog scale, self-administered questionnaire of the ulnar neuropathy at the elbow (SQUNE), and McGowan classification were used for clinical evaluation. Cross-sectional area of the ulnar nerve by US and the electrophysiological severity scale through a nerve conduction study were utilized in the evaluation of morphologic and electrophysiological changes. The cross-sectional area of the ulnar nerve was measured at 3 points of condylar, proximal, and distal level of the cubital tunnel.

Results

No side effects were reported during the study period. The visual analog scale and cross-sectional area showed a significant decrease at 1st week and 4th week, as compared to baseline (p<0.05). The electrophysiological severity scale was significantly decreased at the 4th week, as compared with baseline and 1st week (p<0.05). Among the quantitative components of the scale, there were statistically significant improvements with respect to the conduction velocity and block.

Conclusion

The new approach of US-guided injection may be a safe tool for the treatment of CuTS. Symptomatic and morphologic recoveries preceded the electrophysiological improvement.

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    Aref Nasiri, Farzaneh Rezaei Motlagh, Mohammad Amin Vafaei
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    Tinatin Natroshvili, Milly S. van de Warenburg, Erwin P. Heine, Nicholas J. Slater, Erik T. Walbeehm, Ronald H. M. A. Bartels
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    Clarissa Neves Spitz, Izabela Jardim Rodrigues Pitta, Ligia Rocha Andrade, Anna Maria Sales, Euzenir Nunes Sarno, Nivaldo Ribeiro Villela, Roberta Olmo Pinheiro, Marcia Rodrigues Jardim
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    Christian Dejaco, Pedro M Machado, Francesco Carubbi, Philipp Bosch, Lene Terslev, Giorgio Tamborrini, Luca Maria Sconfienza, Carlo Alberto Scirè, Sebastian Ruetten, Jef van Rompay, Fabian Proft, Costantino Pitzalis, Marina Obradov, Rikke Helene Moe, Vasc
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    Daniela Poenaru, Florina Ojoga, Miruna Sandulescu, Delia Cinteza
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    Kamal Mezian, Jakub Jačisko, Radek Kaiser, Stanislav Machač, Petra Steyerová, Karolína Sobotová, Yvona Angerová, Ondřej Naňka
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    Christian Gronbeck, Jennifer Wolf, Craig M. Rodner
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    Luca Maria Sconfienza, Miraude Adriaensen, Domenico Albano, Georgina Allen, Maria Pilar Aparisi Gómez, Alberto Bazzocchi, Ian Beggs, Bianca Bignotti, Vito Chianca, Angelo Corazza, Danoob Dalili, Miriam De Dea, Jose Luis del Cura, Francesco Di Pietto, Elen
    European Radiology.2020; 30(3): 1498.     CrossRef
  • Ultrasound‐Guided Hydrodissection With Corticosteroid Injection in the Treatment of Carpal Tunnel Syndrome
    Verena J. M. M. Schrier, Jeffrey S. Brault, Peter C. Amadio
    Journal of Ultrasound in Medicine.2020; 39(9): 1759.     CrossRef
  • Perineural Dextrose and Corticosteroid Injections for Ulnar Neuropathy at the Elbow: A Randomized Double-blind Trial
    Liang-Cheng Chen, Tsung-Yen Ho, Yu-Ping Shen, Yu-Chi Su, Tsung-Ying Li, Chia-Kuang Tsai, Yung-Tsan Wu
    Archives of Physical Medicine and Rehabilitation.2020; 101(8): 1296.     CrossRef
  • USG-guided Hydrodissection for Recurrent Ulnar Neuropathy in a Patient with Anteriorly Transposed Nerve
    Vikas Jhanwar, Aakanksha Agarwal, Abhishek Chandra, Meenu Bagarhatta
    Indian Journal of Musculoskeletal Radiology.2020; 2: 125.     CrossRef
  • Nerve hydrodissection for carpal tunnel syndrome: A prospective, randomized, double‐blind, controlled trial
    Yung‐Tsan Wu, Si‐Ru Chen, Tsung‐Ying Li, Tsung‐Yen Ho, Yu‐Ping Shen, Chia‐Kuang Tsai, Liang‐Cheng Chen
    Muscle & Nerve.2019; 59(2): 174.     CrossRef
  • Ultrasound‐guided treatment of peripheral entrapment mononeuropathies
    John W. Norbury, Levon N. Nazarian
    Muscle & Nerve.2019; 60(3): 222.     CrossRef
  • Comparison of perineural platelet‐rich plasma and dextrose injections for moderate carpal tunnel syndrome: A prospective randomized, single‐blind, head‐to‐head comparative trial
    Yu‐Ping Shen, Tsung‐Ying Li, Yu‐Ching Chou, Tsung‐Yen Ho, Ming‐Jen Ke, Liang‐Cheng Chen, Yung‐Tsan Wu
    Journal of Tissue Engineering and Regenerative Medicine.2019; 13(11): 2009.     CrossRef
  • Ulnar Nerve Entrapment at the Cubital Tunnel Successfully Treated with Ultrasound-Guided Peripheral Nerve Hydrodissection: A Case Report and Further Evidence for a Developing Treatment Option
    Jonathan M. Stoddard, Cole R. Taylor, Francis G. O'Connor
    Current Sports Medicine Reports.2019; 18(11): 382.     CrossRef
  • A reliable technique for ultrasound-guided perineural injection in ulnar neuropathy at the elbow
    Ulrike M. Hamscha, Ines Tinhofer, Stefan Heber, Wolfgang Grisold, Wolfgang J. Weninger, Stefan Meng
    Muscle & Nerve.2017; 56(2): 237.     CrossRef
  • Six-month Efficacy of Perineural Dextrose for Carpal Tunnel Syndrome
    Yung-Tsan Wu, Tsung-Yen Ho, Yu-Ching Chou, Ming-Jen Ke, Tsung-Ying Li, Chia-Kuang Tsai, Liang-Cheng Chen
    Mayo Clinic Proceedings.2017; 92(8): 1179.     CrossRef
  • Differential expression of miRNAs in Osborne's ligament of cubital tunnel syndrome
    Xian-Hu Zhou, Yi-Ming Ren, Zhi-Jian Wei, Wei Lin, Bao-You Fan, Shen Liu, Yan Hao, Gui-Dong Shi, Shi-Qing Feng
    Molecular Medicine Reports.2017; 16(1): 687.     CrossRef
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Effects of Repeated Steroid Injection at Subacromial Bursa With Different Interval
Seung Deuk Byun, Yong Ho Hong, Sung Kyung Hong, Jin Won Song, Seung Beom Woo, Jae Hyun Noh, Jong Min Kim, Zee Ihn Lee
Ann Rehabil Med 2014;38(6):805-811.   Published online December 24, 2014
DOI: https://doi.org/10.5535/arm.2014.38.6.805
Objective

To evaluate the effects of repeated steroid injection at subacromial bursa with different interval for patient with periarticular shoulder disorder.

Methods

Group A (n=10) received subacromial bursa injection only on their first visit, group C (n=10) received the injection on their first visit and one week later, and group B (n=10) received the injection on their first visit and two weeks later. All injections were done with a combination of 40 mg (1.0 mL) of triamcinolone and 5.0 mL 0.5% lidocaine (6 mL total). We examined the active range of motion (AROM) of the shoulder joint, visual analogue scale (VAS), and shoulder disability questionnaire (SDQ) at baseline at 1, 2, and 4 weeks after the initial injection.

Results

In VAS, comparing the changes in VAS between groups, group B showed significant improvements compared with group A or C at 4 weeks after the initial injection (p<0.05). In SDQ, comparing the changes in SDQ between the groups, group B and C showed more improvement than group A at 4 weeks after the initial injection, but these results were not statistically significant (p>0.05). In AROM, comparing the changes in AROM of external rotation between groups, group B and C showed significant improvement compared with group A at 4 weeks after the initial injection (p<0.05).

Conclusion

It may be more effective in pain relief for patients with periarticular disorder to receive subacromial bursa injections twice with 2-week interval, as opposed to once.

Citations

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  • Role of Platelet Rich Plasma (PRP) injection in treatment of rotator cuff tear
    Nermin Hassan El Gharbawy, Hossam Salaheldin Labib
    Egyptian Rheumatology and Rehabilitation.2020;[Epub]     CrossRef
  • Ultrasound-guided injection of platelet rich plasma versus corticosteroid for treatment of rotator cuff tendinopathy: Effect on shoulder pain, disability, range of motion and ultrasonographic findings
    Doaa H. Ibrahim, Nagat M. El-Gazzar, Hanan M. El-Saadany, Radwa M. El-Khouly
    The Egyptian Rheumatologist.2019; 41(2): 157.     CrossRef
  • Efficacy of ultrasonography-guided intra-articular steroid injection of the shoulder and excercising in patients with adhesive capsulitis: Glenohumeral versus subacromial approaches
    Soha F. Khallaf, Mervat I. Hussein, Amal M. El-Barbary, Radwa M. El Khouly
    The Egyptian Rheumatologist.2018; 40(4): 277.     CrossRef
  • Early Clinical Outcomes after Subacromial Injection of Ketorolac in Patients with Shoulder Impingement Syndrome: A Comparison with Steroid Injection
    Jieun Kwon, Ye Hyun Lee, Hae Min Kim, Jong Min Kim, Hyun Suk Jung, Seung Rim Yi
    Journal of the Korean Orthopaedic Association.2017; 52(2): 170.     CrossRef
  • The Effectiveness of Ultrasound-guided Bee Venom Pharmacopuncture Combined with Integrative Korean Medical Treatment for Rotator cuff Diseases : A Retrospective Case Series※
    Jeong Kyo Jeong, Gi Nam Park, Kyung Min Kim, So Yun Kim, Eun Seok Kim, Jung Ho Kim, Seung Kyu Nam, Young Il Kim
    The Acupuncture.2016; 33(4): 165.     CrossRef
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Use of Magnetic Resonance Imaging to Identify Outcome Predictors of Caudal Epidural Steroid Injections for Lower Lumbar Radicular Pain Caused by a Herniated Disc
Sung Oh Cha, Chul Hoon Jang, Jin Oh Hong, Joon Sang Park, Jung Hyun Park
Ann Rehabil Med 2014;38(6):791-798.   Published online December 24, 2014
DOI: https://doi.org/10.5535/arm.2014.38.6.791
Objective

We used lumbar magnetic resonance image (MRI) findings to determine possible outcome predictors of a caudal epidural steroid injection (CESI) for radicular pain caused by a herniated lumbar disc (HLD).

Methods

Ninety-one patients with radicular pain whose MRI indicated a HLD were enrolled between September 2010 and July 2013. The CESIs were performed using ultrasound (US). A responder was defined as having complete relief or at least a 50% reduction of pain as assessed by the visual analog scale (VAS) and functional status on the Roland Morris Disability Questionnaire (RMDQ); responder (VAS n=61, RMDQ n=51), and non-responder (VAS n=30, RMDQ n=40). MRI findings were analyzed and compared between the two groups with regard to HLD level, HLD type (protrusion or exclusion), HLD zone (central, subarticular, foraminal, and extraforaminal), HLD volume (mild, moderate, or severe), relationship between HLD and nerve root (no contact, contact, displaced, or compressed), disc height loss (none, less than half, or more than half ), and disc degeneration grade (homogeneous disc structure or inhomogeneous disc structure-clear nucleus and height of intervertebral disc).

Results

A centrally located herniated disc was more common in the responder group than that in the non-responder group. Treatment of centrally located herniated discs showed satisfactory results. (VAS p=0.025, RMDQ p=0.040). Other factors, such as HLD level, HLD type, HLD volume, relationship to nerve root, disc height loss, and disc degeneration grade, were not critical.

Conclusion

The HLD zone was significant for pain reduction after CESI. A centrally located herniated disc was a predictor of a good clinical outcome.

Citations

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  • The role of psychosocial factors in mediating the treatment response of epidural steroid injections for low back pain with or without lumbosacral radiculopathy: A scoping review
    Meredith Stensland, Donald McGeary, Caleigh Covell, Elizabeth Fitzgerald, Mahsa Mojallal, Selena Lugosi, Luke Lehman, Zachary McCormick, Paul Nabity, Rajakumar Anbazhagan
    PLOS ONE.2025; 20(1): e0316366.     CrossRef
  • Transforaminal Epidural Injection for Far Lateral Lumbar Disc Herniations: An Alternative to Surgery or Just a Delay?
    Luay Serifoglu, Mustafa U Etli
    Cureus.2024;[Epub]     CrossRef
  • Prognostic factors associated with outcome following an epidural steroid injection for disc-related sciatica: a systematic review and narrative synthesis
    Alan Nagington, Nadine E. Foster, Kym Snell, Kika Konstantinou, Siobhán Stynes
    European Spine Journal.2023; 32(3): 1029.     CrossRef
  • Effect of Transforaminal Epidural Corticosteroid Injections in Acute Sciatica A Randomized Controlled Trial
    Bastiaan C. Ter Meulen, Johanna M. van Dongen, Esther Maas, Marinus H. van de Vegt, Johan Haumann, Henry C. Weinstein, Raymond Ostelo
    The Clinical Journal of Pain.2023;[Epub]     CrossRef
  • Fluoroscopically guided caudal epidural steroid injections for axial low back pain associated with central disc protrusions: a prospective outcome study
    James J. Lee, Elizabeth T. Nguyen, Julian R. Harrison, Caitlin K. Gribbin, Nicole R. Hurwitz, Jennifer Cheng, Kwadwo Boachie-Adjei, Eric A. Bogner, Peter J. Moley, James F. Wyss, Gregory E. Lutz
    International Orthopaedics.2019; 43(8): 1883.     CrossRef
  • Factors for Predicting Favorable Outcome of Percutaneous Epidural Adhesiolysis for Lumbar Disc Herniation
    Sang Ho Moon, Jae Il Lee, Hyun Seok Cho, Jin Woo Shin, Won Uk Koh
    Pain Research and Management.2017; 2017: 1.     CrossRef
  • The Effectiveness of Transforaminal Versus Caudal Routes for Epidural Steroid Injections in Managing Lumbosacral Radicular Pain
    Jun Liu, Hengxing Zhou, Lu Lu, Xueying Li, Jun Jia, Zhongju Shi, Xue Yao, Qiuli Wu, Shiqing Feng
    Medicine.2016; 95(18): e3373.     CrossRef
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Analgesic Effect of Intrathecal Gabapentin in a Rat Model of Persistent Muscle Pain
Tae-Wook Kang, Min Kyun Sohn, Noh Kyoung Park, Sang Hyung Ko, Kyoung Jin Cho, Jaewon Beom, Sangkuk Kang
Ann Rehabil Med 2014;38(5):682-688.   Published online October 30, 2014
DOI: https://doi.org/10.5535/arm.2014.38.5.682
Objective

To evaluate the analgesic effect of intrathecal gabapentin therapy on secondary hyperalgesia in a rat model of persistent muscle pain.

Methods

Intrathecal catheters were implanted into rats. Mechanical secondary hyperalgesia was induced by repeated intramuscular injections of acidic solution into the gastrocnemius muscle. Gabapentin was administrated intrathecally. Rats were allocated to control and experimental (gabapentin 30, 100, 300, and 1,000 µg) group. After gabapentin administration, mechanical withdrawal threshold was measured every 15 minutes and the motor function was measured 30 minutes later.

Results

Mechanical hyperalgesia was evoked after the second acidic buffer injection. There was a significant improvement on the mechanical threshold after administration of 100, 300, and 1,000 µg gabapentin compared to pre-injection and the control group. The analgesic effect continued for 105, 135, and 210 minutes, respectively. To discern side effects, motor function was measured. Motor function was preserved in both groups after gabapentin administration, except for rats who received 1,000 µg gabapentin.

Conclusion

Intrathecal gabapentin administration produces dose-dependent improvements in mechanical hyperalgesia in a persistent muscle pain rat model. This implicates the central nervous system as having a strong influence on the development of persistent mechanical hyperalgesia. These results are helpful in understanding the pathophysiology of secondary hyperalgesia and in the treatment of patients with chronic muscle pain.

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  • Investigating the ameliorative effect of alpha‐mangostin on development and existing pain in a rat model of neuropathic pain
    Mahboobeh Ghasemzadeh Rahbardar, Bibi Marjan Razavi, Hossein Hosseinzadeh
    Phytotherapy Research.2020; 34(12): 3211.     CrossRef
  • Gabapentin decreases microglial cells and reverses bilateral hyperalgesia and allodynia in rats with chronic myositis
    A.S. Rosa, M.F. Freitas, I.R.C. Rocha, M. Chacur
    European Journal of Pharmacology.2017; 799: 111.     CrossRef
  • Gabapentin Effects on PKC-ERK1/2 Signaling in the Spinal Cord of Rats with Formalin-Induced Visceral Inflammatory Pain
    Yan-bo Zhang, Zheng-dong Guo, Mei-yi Li, Peter Fong, Ji-guo Zhang, Can-wen Zhang, Ke-rui Gong, Ming-feng Yang, Jing-zhong Niu, Xun-ming Ji, Guo-wei Lv, Yvette Tache
    PLOS ONE.2015; 10(10): e0141142.     CrossRef
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Randomized Controlled Trial for Efficacy of Capsular Distension for Adhesive Capsulitis: Fluoroscopy-Guided Anterior Versus Ultrasonography-Guided Posterolateral Approach
Jae Hyun Bae, Young Sook Park, Hyun Jung Chang, Min Jung Kim, Kang Young Park, Seung Hwan Jin, Eun Hee Lee
Ann Rehabil Med 2014;38(3):360-368.   Published online June 26, 2014
DOI: https://doi.org/10.5535/arm.2014.38.3.360
Objective

To find the most effective procedure to treat adhesive capsulitis of the shoulder, we evaluated the clinical effects of an ultrasonographic-guided anterior approach capsular distension and a fluoroscopy-guided posterolateral approach capsular distension. We expected the anterior approach to be better than the posterolateral approach because the rotator interval, a triangular anatomic area in the anterosuperior aspect of the shoulder, which is considered an important component of the pathology of adhesive capsulitis.

Methods

Participants were randomly assigned to two groups: 27 patients in group A were injected by an anterior approach with 2% lidocaine (5 mL), contrast dye (5 mL), triamcinolone (40 mg), and normal saline (9 mL) under fluoroscopic guidance in the operating room. Twenty-seven patients in group B were injected using a posterolateral approach with 2% lidocaine (5 mL), triamcinolone (40 mg), and normal saline (14 mL) under ultrasonographic guidance. After injection, all patients received physiotherapy four times in the first postoperative week and then two times each week for eight more weeks. Treatment effects were assessed using the shoulder pain and disability index (SPADI), visual numeric scale (VNS), passive range of motion (PROM), hand power (grip and pinch) at baseline and at one week, five and nine weeks after injection.

Results

SPADI, VNS, PROM, and hand power improved in one week, five and nine weeks in both groups. Statistically significant differences were not observed in SPADI, VNS, PROM, or hand power between groups.

Conclusion

Ultrasonography-guided capsular distension by a posterolateral approach has similar effects to fluoroscopy-guided capsular distension by an anterior approach.

Citations

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  • A prospective, randomized, blinded study on the efficacy of using corticosteroids in hydrodilatation as a treatment for adhesive capsulitis of the shoulder
    Joan Tomàs Gebellí-Jové, Antonio Buñuel-Viñau, Marta Canela-Capdevila, Jordi Camps, Fàtima Sabench, Petrea Iftimie-Iftimie
    Shoulder & Elbow.2025; 17(3): 274.     CrossRef
  • A Comparative Study Between Hydrodilatation and Intra-Articular Corticosteroid Injection in Patients with Shoulder Adhesive Capsulitis: A Single-Blinded Randomized Clinical Trial
    Aref Nasiri, Maryam Mirhadi, Vahideh Nadgaran, Amirsalar Motamedi, Maryamsadat Fakheri
    Journal of Pain & Palliative Care Pharmacotherapy.2025; 39(2): 286.     CrossRef
  • Use and safety of corticosteroid injections in joints and musculoskeletal soft tissue: guidelines from the American Society of Regional Anesthesia and Pain Medicine, the American Academy of Pain Medicine, the American Society of Interventional Pain Physic
    Honorio T Benzon, David Anthony Provenzano, Ameet Nagpal, Dmitri Souza, Maxim S Eckmann, Ariana M Nelson, Maged Mina, Alaa Abd-Elsayed, Dalia Elmofty, Andrea L Chadwick, Tina L Doshi, Carlos A Pino, Maunak Rana, Shalini Shah, Hariharan Shankar, Alison Sto
    Regional Anesthesia & Pain Medicine.2025; : rapm-2024-105656.     CrossRef
  • Efficacy of Combination Therapy (Hydrodilatation and Subdeltoid Bursa Injection With Corticosteroid, Mobilization, and Physical Therapy) vs Physical Therapy Alone for Treating Frozen Shoulder: A Randomized Single-Blind Controlled Trial, Phase I
    Yu-Hao Huang, Ying-Chen Kuo, Lin-Fen Hsieh, Chun-Mei Tsai, Ya-Fang Liu, Tien-Lee Hsieh
    Archives of Physical Medicine and Rehabilitation.2024; 105(4): 631.     CrossRef
  • Corticosteroid Injection Methods for Frozen Shoulder: A Network Meta-analysis
    Chun-Wei Liang, Hsiao-Yi Cheng, Yu-Hao Lee, Chun- De Liao, Shih-Wei Huang
    Archives of Physical Medicine and Rehabilitation.2024; 105(4): 750.     CrossRef
  • Comparative outcome of ultrasound guided vs. fluoroscopy guided hydrodilatation in adhesive capsulitis: a prospective study
    Mehtab Ahmad
    International Journal of Burns and Trauma.2024; 14(4): 65.     CrossRef
  • Efficacy of hydrodilatation in frozen shoulder: a systematic review and meta-analysis
    Daryl Poku, Rifat Hassan, Filippo Migliorini, Nicola Maffulli
    British Medical Bulletin.2023; 147(1): 121.     CrossRef
  • Peripheral Joint Injections
    Austin Marcolina, Kevin Vu, George Chang Chien
    Physical Medicine and Rehabilitation Clinics of North America.2022; 33(2): 267.     CrossRef
  • Intra-articular distension preceded by physical therapy versus intra-articular distension followed by physical therapy for treating adhesive capsulitis of the shoulder
    Anis Jellad, Wafa May, Ahmed Zrig, Amine Kalai, Mahbouba Jguirim, Zohra Ben Salah Frih, Mondher Golli
    Journal of Back and Musculoskeletal Rehabilitation.2020; 33(3): 443.     CrossRef
  • Comparative Efficacy of Intra-Articular Steroid Injection and Distension in Patients With Frozen Shoulder: A Systematic Review and Network Meta-Analysis
    Meng-Ting Lin, Ming-Yen Hsiao, Yu-Kang Tu, Tyng-Guey Wang
    Archives of Physical Medicine and Rehabilitation.2018; 99(7): 1383.     CrossRef
  • Correlations between MRI findings and outcome of capsular distension in adhesive capsulitis of the shoulder
    Yun Hee Park, Young Sook Park, Hyun Jung Chang, Yeongmi Kim
    Journal of Physical Therapy Science.2016; 28(10): 2798.     CrossRef
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Short-Term Change of Handgrip Strength After Trigger Point Injection in Women With Muscular Pain in the Upper Extremities
Soo Jin Lee, Dong Heun Ahn, Ji Hun Jung, Yong Rok Kim, Young Jin Lee
Ann Rehabil Med 2014;38(2):241-248.   Published online April 29, 2014
DOI: https://doi.org/10.5535/arm.2014.38.2.241
Objective

To determine overall handgrip strength (HGS), we assessed the short-term change of HGS after trigger point injection (TPI) in women with muscular pain in the upper extremities by comparison with established pain scales.

Methods

The study enrolled 50 female patients (FMS with MPS group: 29 patients with combined fibromyalgia [FMS] and myofascial pain syndrome [MPS]; MPS group: 21 patients with MPS) who presented with muscular pain in the upper extremities at Konyang University Hospital. In addition, a total of 9 healthy women (control group) were prospectively enrolled in the study. We surveyed the three groups using the following established pain scales: the Fibromyalgia Impact Questionnaire (FIQ), the 36-Item Short Form Health Survey (SF-36), and the Short Form McGill Pain Questionnaire (MPQ). HGS was measured in both hands of study participants using a handgrip dynamometer. We performed TPI (0.5% lidocaine, total 10 mL, injected at the pain site of upper extremities). After 20 minutes, we remeasured the patient's HGS and MPQ score.

Results

ANOVA analysis was conducted among groups. Based on Tukey multiple comparison test, the majority of FIQ and SF-36 subscales, total FIQ and SF-36 scores, MPQ and HGS were significantly different between FMS with MPS and the other groups. There was no statistically significant difference between MPS and control groups. Higher HGS was positively associated with enhanced physical function, negatively associated with total FIQ and MPQ scores, and positively associated with the total SF-36 score calculated using Spearman correlation. Post-TPI MPQ decreased and HGS increased. In patient groups, a negative correlation was found between MPQ and HGS.

Conclusion

The HGS test might potentially be a complementary tool in assessing the short-term treatment effects of women with muscular pain in the upper extremities.

Citations

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  • Dry Needling on the Infraspinatus Latent and Active Myofascial Trigger Points in Older Adults With Nonspecific Shoulder Pain: A Randomized Clinical Trial
    César Calvo-Lobo, Soraya Pacheco-da-Costa, Jorge Martínez-Martínez, David Rodríguez-Sanz, Pedro Cuesta-Álvaro, Daniel López-López
    Journal of Geriatric Physical Therapy.2018; 41(1): 1.     CrossRef
  • Consideration of the Efficacy of Nerve Block Therapy and Trigger Point Injection (Tender Point Injection) Therapy in Fibromyalgia
    Fukami Nakajima
    Journal of The Society of Japanese Women Scientists.2018; 18(1): 29.     CrossRef
  • Massage therapy in cortisol circadian rhythm, pain intensity, perceived stress index and quality of life of fibromyalgia syndrome patients
    Felipe Rodrigues de Oliveira, Laura Cristina Visnardi Gonçalves, Filipy Borghi, Larissa Gabriela Rocha Ventura da Silva, Anne Elise Gomes, Gustavo Trevisan, Aglécio Luiz de Souza, Dora Maria Grassi-Kassisse, Danilo Roberto Xavier de Oliveira Crege
    Complementary Therapies in Clinical Practice.2018; 30: 85.     CrossRef
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The Comparison of Effects of Suprascapular Nerve Block, Intra-articular Steroid Injection, and a Combination Therapy on Hemiplegic Shoulder Pain: Pilot Study
Woo Hyun Jeon, Gun Woong Park, Ho Joong Jeong, Young Joo Sim
Ann Rehabil Med 2014;38(2):167-173.   Published online April 29, 2014
DOI: https://doi.org/10.5535/arm.2014.38.2.167
Objective

To assess the relative effectiveness of three injections methods suprascapular nerve block (SSNB) alone, intra-articular steroid injection (IAI) alone, or both-on relief of hemiplegic shoulder pain.

Methods

We recruited 30 patients with hemiplegic shoulder pain after stroke. SSNB was performed in 10 patients, IAI in 10 patients, and a combination of two injections in 10 patients. All were ultrasonography guided. Each patient's maximum passive range of motion (ROM) in the shoulder was measured, and the pain intensity level was assessed with a visual analogue scale (VAS). Repeated measures were performed on pre-injection, and after injection at 1 hour, 1 week, and 1 month. Data were analyzed by Kruskal-Wallis and Friedman tests.

Results

All variables that were repeatedly measured showed significant differences in shoulder ROM with time (p<0.05), but there was no difference according injection method. In addition, VAS was statistically significantly different with time, but there was no difference by injection method. Pain significantly decreased until a week after injection, but pain after a month was relatively increased. However, pain was decreased compared to pre-injection.

Conclusion

The three injection methods significantly improved shoulder ROM and pain with time, but no statistically significant difference was found between them.

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    Praveen Kumar, Avgi Christodoulou, Michael Loizou
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    Wenjuan Yu, Luoluo Wang, Yige Li, Shuwei Tao, Qingrui Li, Mingyue Zhu
    Physikalische Medizin, Rehabilitationsmedizin, Kurortmedizin.2024; 34(05): 280.     CrossRef
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    Arvind K Sharma, Satyasheel S Asthana, Indrajit Deshmukh
    Cureus.2024;[Epub]     CrossRef
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    Asude Uzdu, Yeşim Kirazlı, Hale Karapolat, Burcu Unlu, Göksel Tanıgör, Funda Atamaz Çalış
    Neurological Sciences.2021; 42(5): 1977.     CrossRef
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    Neil Smith, Ziheng Liew, Samantha Johnson, David R Ellard, Martin Underwood, Rebecca Kearney
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    Hiroki Funao, Mayumi Tsujikawa, Ryo Momosaki, Motomu Shimaoka
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    Yi-Hsiang Chiu, Ke-Vin Chang, Wei-Ting Wu, Po-Cheng Hsu, Levent Özçakar
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    Neurological Sciences.2020; 41(8): 2225.     CrossRef
  • Suprascapular nerve block in hemiplegic shoulder pain: comparison of the effectiveness of placebo, local anesthetic, and corticosteroid injections—a randomized controlled study
    Rana Terlemez, Selda Çiftçi, Mahir Topaloglu, Beril Dogu, Figen Yilmaz, Banu Kuran
    Neurological Sciences.2020; 41(11): 3243.     CrossRef
  • Effects of fluoroscopy-guided intraarticular injection, suprascapular nerve block, and combination therapy in hemiplegic shoulder pain: a prospective double-blind, randomized clinical study
    Savas Sencan, Alp Eren Celenlioglu, Evrim Karadag-Saygı, İpek Midi, Osman Hakan Gunduz
    Neurological Sciences.2019; 40(5): 939.     CrossRef
  • Efficacy of ultrasound-guided suprascapular nerve block treatment in patients with painful hemiplegic shoulder
    Tuğba Aydın, Ekin İlke Şen, Merve Yıldız Yardımcı, Fatma Nur Kesiktaş, Kadriye Öneş, Nurdan Paker
    Neurological Sciences.2019; 40(5): 985.     CrossRef
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    Donghwi Park, Kwang Jae Yu, Ju Young Cho, Seung Beom Woo, Junu Park, Zeeihn Lee, Jong Min Kim
    Medicine.2017; 96(46): e8741.     CrossRef
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    Min Cheol Chang
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    Alessandro Picelli, Sara Bonazza, Davide Lobba, Massimo Parolini, Alvise Martini, Elena Chemello, Marialuisa Gandolfi, Enrico Polati, Nicola Smania, Vittorio Schweiger
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Appropriate Depth of Needle Insertion During Rhomboid Major Trigger Point Block
Seung Jun Seol, Hyungpil Cho, Do Hyun Yoon, Seong Ho Jang
Ann Rehabil Med 2014;38(1):72-76.   Published online February 25, 2014
DOI: https://doi.org/10.5535/arm.2014.38.1.72
Objective

To investigate an appropriate depth of needle insertion during trigger point injection into the rhomboid major muscle.

Methods

Sixty-two patients who visited our department with shoulder or upper back pain participated in this study. The distance between the skin and the rhomboid major muscle (SM) and the distance between the skin and rib (SB) were measured using ultrasonography. The subjects were divided into 3 groups according to BMI: BMI less than 23 kg/m2 (underweight or normal group); 23 kg/m2 or more to less than 25 kg/m2 (overweight group); and 25 kg/m2 or more (obese group). The mean±standard deviation (SD) of SM and SB of each group were calculated. A range between mean+1 SD of SM and the mean-1 SD of SB was defined as a safe margin.

Results

The underweight or normal group's SM, SB, and the safe margin were 1.2±0.2, 2.1±0.4, and 1.4 to 1.7 cm, respectively. The overweight group's SM and SB were 1.4±0.2 and 2.4±0.9 cm, respectively. The safe margin could not be calculated for this group. The obese group's SM, SB, and the safe margin were 1.8±0.3, 2.7±0.5, and 2.1 to 2.2 cm, respectively.

Conclusion

This study will help us to set the standard depth of safe needle insertion into the rhomboid major muscle in an effective manner without causing any complications.

Citations

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    Tsunehiko Wada, Miyono Okinaka, Kodai Kawasaki, Yuika Onozaki, Keigo Hayakawa, Syota Fukumaru
    Journal of Physical Therapy Science.2025; 37(2): 84.     CrossRef
  • Ultrasound-guided serratus posterior superior muscle block: an anatomical study investigating the extent of injected dye and the mechanism of action of a simulated injection in Thiel soft-embalmed cadavers
    Atsushi Sawada, Tatsuya Kunigo, Yuki Ohsaki, Kanna Nagaishi, Michiaki Yamakage
    Journal of Anesthesia.2025;[Epub]     CrossRef
  • Association of activities of daily living and cognitive function with thickness of the upper extremity muscles in children and adults with cerebral palsy
    Mitsuhiro Masaki, Yuki Uchikawa, Yuka Iizuka, Karin Sugawara, Honoka Isobe, Fuyumi Hattori, Mami Okamoto, Saki Takahashi, Emina Morohashi, Yuki Kitamura
    Journal of Medical Ultrasonics.2023; 50(2): 245.     CrossRef
  • A Cadaveric Study of a Safe and Accurate Electromyographic Needle Approach to the Rhomboid Major
    Ki Hoon Kim, Hong Bum Park, Dasom Kim, Im Joo Rhyu, Dong Hwee Kim
    American Journal of Physical Medicine & Rehabilitation.2023; 102(5): 404.     CrossRef
  • Trigger Point Injections
    Malathy Srinivasan, Christopher Lam, John Alm, Andrea L. Chadwick
    Physical Medicine and Rehabilitation Clinics of North America.2022; 33(2): 307.     CrossRef
  • Effectiveness of ultrasound-guided fascia hydrorelease on the coracohumeral ligament in patients with global limitation of the shoulder range of motion: a pilot study
    Hiroaki Kimura, Masei Suda, Tadashi Kobayashi, Shigeki Suzuki, Sho Fukui, Hideaki Obata
    Scientific Reports.2022;[Epub]     CrossRef
  • Accuracy of rib palpation for dry needling of deep periscapular musculature, measured with ultrasound
    Daniel M. Cushman, Linda Vernon Scholl, Monica Ludlow, Shellie Cunningham, Masaru Teramoto
    Journal of Bodywork and Movement Therapies.2021; 26: 7.     CrossRef
  • Prediction model of rhomboid major and pleura depth based on anthropometric features to decrease the risk of pneumothorax during dry needling
    Juan Antonio Valera‐Calero, Enrique Cendra‐Martel, Tomás Fernández‐Rodríguez, César Fernández‐de‐las‐Peñas, Gracia María Gallego‐Sendarrubias, Jesús Guodemar‐Pérez
    International Journal of Clinical Practice.2021;[Epub]     CrossRef
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    Jerrold Petrofsky, Michael Laymon, Haneul Lee
    Journal of Back and Musculoskeletal Rehabilitation.2020; 33(1): 21.     CrossRef
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    Parinaz Abiri, Arash Abiri, Varun Gudapati, Chih-Chiang Chang, Mehrdad Roustaei, Hamed Bourenane, Usama Anwar, Dejan Markovic, Tzung K. Hsiai
    Annals of Biomedical Engineering.2020; 48(4): 1368.     CrossRef
  • Enhancing Trigger Point Dry Needling Safety by Ultrasound Skin-to-Rib Measurement: An inter-Rater Reliability Study
    Anna Folli, Alessandro Schneebeli, Simone Ballerini, Francesca Mena, Emiliano Soldini, César Fernández-de-las-Peñas, Marco Barbero
    Journal of Clinical Medicine.2020; 9(6): 1958.     CrossRef
  • Intramuscular Neural Distribution of Rhomboid Muscles: Evaluation for Botulinum Toxin Injection Using Modified Sihler’s Method
    Kyu-Ho Yi, Hyung-Jin Lee, You-Jin Choi, Ji-Hyun Lee, Kyung-Seok Hu, Hee-Jin Kim
    Toxins.2020; 12(5): 289.     CrossRef
  • Positional changes in distance to the pleura and in muscle thickness for dry needling
    Ulrike H. Mitchell, A. Wayne Johnson, Robert E. Larson, Cameron T. Seamons
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    Ki Hoon Kim, Goo Young Kim, Seong Gyu Lim, Byung Kyu Park, Dong Hwee Kim
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    Daniel Cushman, Michael Henrie, Linda Vernon Scholl, Monica Ludlow, Masaru Teramoto
    Muscle & Nerve.2018; 57(1): 61.     CrossRef
  • Comparison of the Efficiency of Ultrasound‐Guided Injections of the Rhomboid Major and Trapezius Muscles in Myofascial Pain Syndrome: A Prospective Randomized Controlled Double‐blind Study
    Burcu Metin Ökmen, Korgün Ökmen, Lale Altan
    Journal of Ultrasound in Medicine.2018; 37(5): 1151.     CrossRef
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    T. Sha, L.L. Gao, C.H. Zhang, J.G. Zheng, Z.H. Meng
    QJM.2016; 109(10): 639.     CrossRef
  • Pneumothorax after trigger point injection: A case report and review of literature
    Elif Oral Ahiskalioglu, Haci Ahmet Alici, Aysenur Dostbil, Mine Celik, Ali Ahiskalioglu, Mehmet Aksoy
    Journal of Back and Musculoskeletal Rehabilitation.2016; 29(4): 895.     CrossRef
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    Jihyun Lee, Wonsug Jung
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Efficacy of Epidural Neuroplasty Versus Transforaminal Epidural Steroid Injection for the Radiating Pain Caused by a Herniated Lumbar Disc
Hae Jong Kim, Byeong Cheol Rim, Jeong-Wook Lim, Noh Kyoung Park, Tae-Wook Kang, Min Kyun Sohn, Jaewon Beom, Sangkuk Kang
Ann Rehabil Med 2013;37(6):824-831.   Published online December 23, 2013
DOI: https://doi.org/10.5535/arm.2013.37.6.824
Objective

To compare the treatment effects of epidural neuroplasty (NP) and transforaminal epidural steroid injection (TFESI) for the radiating pain caused by herniated lumbar disc.

Methods

Thirty-two patients diagnosed with herniated lumbar disc through magnetic resonance imaging or computed tomography were included in this study. Fourteen patients received an epidural NP and eighteen patients had a TFESI. The visual analogue scale (VAS) and functional rating index (FRI) were measured before the treatment, and at 2 weeks, 4 weeks and 8 weeks after the treatment.

Results

In the epidural NP group, the mean values of the VAS before the treatment, and at 2 weeks, 4 weeks and 8 weeks after the treatment were 7.00±1.52, 4.29±1.20, 2.64±0.93, 1.43±0.51 and those of FRI were 23.57±3.84, 16.50±3.48, 11.43±2.44, 7.00±2.15. In the TFESI group, the mean values of the VAS before the treatment, and at 2 weeks, 4 weeks and 8 weeks after the treatment were 7.22±2.05, 4.28±1.67, 2.56±1.04, 1.33±0.49 and those of FRI were 22.00±6.64, 16.22±5.07, 11.56±4.18, 8.06±1.89. During the follow-up period, the values of VAS and FRI within each group were significantly reduced (p<0.05) after the treatment. But there were no significant differences between the two groups statistically.

Conclusion

Epidural NP and TFESI are equally effective treatments for the reduction of radiating pain and for improvement of function in patients with a herniated lumbar disc. We recommend that TFESI should be primarily applied to patients who need interventional spine treatment, because it is easier and more cost-effective than epidural NP.

Citations

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  • Effectiveness of intradiscal ozone injections for treating pain following herniated lumbar disc: A systematic review and meta-analysis
    Min Cheol Chang, Yoo Jin Choo, Isabelle Denis, Christopher Mares, Carl Majdalani, Seoyon Yang
    Journal of Back and Musculoskeletal Rehabilitation.2024; 37(5): 1131.     CrossRef
  • Comparison of Clinical Effects and Physical Examination of Transforaminal and Caudal Steroid Injection With Targeted Catheter in Lumbar Radiculopathy: A Single‐Blind Randomized Clinical Trial
    Farnad Imani, Faezeh Mohammad‐Esmaeel, Seyedeh‐Fatemeh Morsalli, Ali Ahani‐Azari, Mahzad Alimian, Nasim Nikoubakht, Azadeh Emami
    Brain and Behavior.2024;[Epub]     CrossRef
  • EVALUATION OF THE EFFICACY OF PERCUTANEOUS CAUDAL AND COMBINED CAUDAL/TRANSFORAMINAL NEUROPLASTY-ADESIOLYSIS FOR TREATING SYMPTOMATIC LUMBAR SPINAL STENOSIS
    Mehmet Osman Akçakaya, Alparslan Aşır, Savaş Çömlek
    Journal of Turkish Spinal Surgery.2023; 34(2): 61.     CrossRef
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    Doo-Hwan Kim, Jin-Woo Shin, Seong-Soo Choi
    Anesthesia and Pain Medicine.2022; 17(4): 361.     CrossRef
  • Comparison of Clinical Results between Percutaneous Epidural Neuroplasty and Trans-Foraminal Epidural Block for Lumbar Foraminal Stenosis
    Seung-Woo Shim, Min-Young Kim, Young-Jae Kim, Yong-Soo Choi
    Journal of Korean Society of Spine Surgery.2022; 29(4): 107.     CrossRef
  • Nonsurgical treatments for patients with radicular pain from lumbosacral disc herniation
    Jung Hwan Lee, Kyoung Hyo Choi, Seok Kang, Dong Hwan Kim, Du Hwan Kim, Bo Ryun Kim, Won Kim, Jung Hwan Kim, Kyung Hee Do, Jong Geol Do, Ju Seok Ryu, Kyunghoon Min, Sung Gin Bahk, Yun Hee Park, Heui Je Bang, Kyoung-ho Shin, Seoyon Yang, Hee Seung Yang, Seu
    The Spine Journal.2019; 19(9): 1478.     CrossRef
  • Factors Associated with Successful Response to Balloon Decompressive Adhesiolysis Neuroplasty in Patients with Chronic Lumbar Foraminal Stenosis
    Yul Oh, Doo-Hwan Kim, Jun-Young Park, Gyu Yeul Ji, Dong Ah Shin, Sang Won Lee, Jin Kyu Park, Jin-Woo Shin, Seong-Soo Choi
    Journal of Clinical Medicine.2019; 8(11): 1766.     CrossRef
  • The effect of additional transforaminal epidural blocks on percutaneous epidural neuroplasty with a wire-type catheter
    Ho Young Gil, Sook Young Lee, Sang Kee Min, Ji Eun Kim, Hye Seon Lee, Hae Won Jeong, Bumhee Park, Jinhee Choung, Jong Bum Choi
    Medicine.2019; 98(50): e18233.     CrossRef
  • Epidural neuroplasty/epidural adhesiolysis
    Se Hee Kim, Sang Sik Choi
    Anesthesia and Pain Medicine.2016; 11(1): 14.     CrossRef
  • Safety of Epidural Corticosteroid Injections
    Ippokratis Pountos, Michalis Panteli, Gavin Walters, Dudley Bush, Peter V. Giannoudis
    Drugs in R&D.2016; 16(1): 19.     CrossRef
  • 7,748 View
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Ischemic Compression After Trigger Point Injection Affect the Treatment of Myofascial Trigger Points
Soo A Kim, Ki Young Oh, Won Hyuck Choi, In Kyum Kim
Ann Rehabil Med 2013;37(4):541-546.   Published online August 26, 2013
DOI: https://doi.org/10.5535/arm.2013.37.4.541
Objective

To investigate the effects of trigger point injection with or without ischemic compression in treatment of myofascial trigger points in the upper trapezius muscle.

Methods

Sixty patients with active myofascial trigger points in upper trapezius muscle were randomly divided into three groups: group 1 (n=20) received only trigger point injections, group 2 (n=20) received trigger point injections with 30 seconds of ischemic compression, and group 3 (n=20) received trigger point injections with 60 seconds of ischemic compression. The visual analogue scale, pressure pain threshold, and range of motion of the neck were assessed before treatment, immediately after treatment, and 1 week after treatment. Korean Neck Disability Indexes were assessed before treatment and 1 week after treatment.

Results

We found a significant improvement in all assessment parameters (p<0.05) in all groups. But, receiving trigger point injections with ischemic compression group showed significant improvement as compared with the receiving only trigger point injections group. And no significant differences between receiving 30 seconds of ischemic compression group and 60 seconds of ischemic compression group.

Conclusion

This study demonstrated the effectiveness of ischemic compression for myofascial trigger point. Trigger point injections combined with ischemic compression shows better effects on treatment of myofascial trigger points in the upper trapezius muscle than the only trigger point injections therapy. But the duration of ischemic compression did not affect treatment of myofascial trigger point.

Citations

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  • Treatment of upper trapezius myofascial trigger points does not influence pain in individuals with shoulder pain: A randomized trial
    Alyssa Conte da Silva, Ana Karoline Nazário, Jéssica Bianca Aily, Stela Marcia Mattiello
    Journal of Bodywork and Movement Therapies.2025; 42: 71.     CrossRef
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    Anita R Gross, Haejung Lee, Jeanette Ezzo, Nejin Chacko, Geoffrey Gelley, Mario Forget, Annie Morien, Nadine Graham, Pasqualina L Santaguida, Maureen Rice, Craig Dixon
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    Alyssa Conte da Silva, Jéssica Bianca Aily, Stela Marcia Mattiello
    Journal of Bodywork and Movement Therapies.2023; 36: 335.     CrossRef
  • Effect of Inhalation Aromatherapy on Pain, Anxiety, Comfort, and Cortisol Levels During Trigger Point Injection
    Kadriye Sayin Kasar, Yasemin Yildirim, Fisun Senuzun Aykar, Meltem Uyar, Ferhan Girgin Sagin, Sevcan Atay
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    Mohamed Salaheldein Alayat, Kadrya Hosney Battecha, Ahmed Mohamed ELsodany, Mohamed Ibrahim Ali
    Journal of Physical Therapy Science.2020; 32(7): 422.     CrossRef
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    A. Pignatelli Vilajeliu, N. Mestre Farràs, F. Escalada Recto, M. Coll Molinos
    Rehabilitación.2020; 54(3): 181.     CrossRef
  • The Effectiveness of Ischemic Compression Technique on Pain and Function in Individuals With Shoulder Pain: A Systematic Review
    Alyssa Conte da Silva, Marcos De Noronha, Ricardo Marcos Liberatori-Junior, Jéssica Bianca Aily, Glaucia Helena Gonçalves, Cristina Arrais-Lima, Ludmilla Maria Souza Mattos de Araújo Vieira, Stela Marcia Mattiello
    Journal of Manipulative and Physiological Therapeutics.2020; 43(3): 234.     CrossRef
  • Effects of Integrated Neuromuscular Inhibition Technique on pain threshold and pain intensity in patients with upper trapezius trigger points
    Zahra Saadat, Ladan Hemmati, Soraya Pirouzi, Mahnaz Ataollahi, Fatemeh Ali-mohammadi
    Journal of Bodywork and Movement Therapies.2018; 22(4): 937.     CrossRef
  • Short term effectiveness of Pressure Release and Kinesiotaping in Cervical Myofascial Pain caused by sternocleidomastoid muscle: A randomized clinical trial
    M.Á. Capó-Juan, A. Grávalos-Gasull, M. Bennasar-Veny, A. Aguiló-Pons, A. Gamundí-Gamundí, J.E. De Pedro-Gómez
    Fisioterapia.2017; 39(2): 68.     CrossRef
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    Jorge Hugo Villafañe, Pablo Herrero
    Journal of Hand Therapy.2016; 29(1): 89.     CrossRef
  • The immediate effect of multiple mechanical impulses on electromyography and pressure pain threshold of lumbar latent trigger points: an experimental study
    Bert Ameloot, Jeff Bagust
    Chiropractic & Manual Therapies.2016;[Epub]     CrossRef
  • Ischemic Compression After Dry Needling of a Latent Myofascial Trigger Point Reduces Postneedling Soreness Intensity and Duration
    Aitor Martín‐Pintado‐Zugasti, Daniel Pecos‐Martin, Ángel Luis Rodríguez‐Fernández, Isabel María Alguacil‐Diego, Alicia Portillo‐Aceituno, Tomás Gallego‐Izquierdo, Josue Fernandez‐Carnero
    PM&R.2015; 7(10): 1026.     CrossRef
  • Comparison of Dry Needling versus Orthopedic Manual Therapy in Patients with Myofascial Chronic Neck Pain: A Single-Blind, Randomized Pilot Study
    Irene Campa-Moran, Etelvina Rey-Gudin, Josué Fernández-Carnero, Alba Paris-Alemany, Alfonso Gil-Martinez, Sergio Lerma Lara, Almudena Prieto-Baquero, José Luis Alonso-Perez, Roy La Touche
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    Gang Wang, Qian Gao, Jingshan Hou, Jun Li, Ching-Liang Hsieh
    Evidence-Based Complementary and Alternative Medicine.2014;[Epub]     CrossRef
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  • 45 Download
  • 14 Crossref

Case Report

A Case of the Cauda Equina Syndrome Associated With the Intrathecal Chemotherapy in a Patient With Primary Central Nervous System Lymphoma
Seunglee Park, Jung-Il Kang, Hyun Bang, Bo-Ram Kim, Jongmin Lee
Ann Rehabil Med 2013;37(3):420-425.   Published online June 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.3.420

The intrathecal chemotherapy with methotrexate and cytarabine arabinoside is used for the treatment and prophylaxis of the primary central nervous system lymphoma. The therapy may induce neurotoxicity including the cauda equina syndrome. We report a case of a 58-year-old man with the diffuse large B-cell lymphoma, who developed the cauda equina syndrome after the administration of intrathecal methotrexate and cytarabine arabinoside, as diagnosed by the electrodiagnostic, urodynamic, and radiologic approaches.

Citations

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  • Drug‐Induced Cauda Equina Syndrome in an 8‐Year‐Old Boy With Acute Lymphoblastic Leukemia: An Uncommon Case Report
    Marzieh Babaee, Mohsen Javadzadeh, Ali Hazeghi
    Clinical Case Reports.2025;[Epub]     CrossRef
  • Acute lumbar polyradiculoneuropathy as early sign of methotrexate intrathecal neurotoxicity: Case report and literature review
    Carmen Montejo, Judith Navarro‐Otano, Gerard Mayà‐Casalprim, Michela Campolo, Jordi Casanova‐Mollá
    Clinical Case Reports.2019; 7(4): 638.     CrossRef
  • FDG-Avid Intrathecal Inflammation Following Administration of Intrathecal Methotrexate
    Molly P. Hogan, Joseph Osborne, Gary A. Ulaner
    Clinical Nuclear Medicine.2016; 41(12): 995.     CrossRef
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  • 32 Download
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Original Article
A Comparison of the Short-Term Effects of a Botulinum Toxin Type A and Triamcinolone Acetate Injection on Adhesive Capsulitis of the Shoulder
Young-Jin Joo, Se-Jin Yoon, Chang-Won Kim, Jung-Hwan Lee, Young-Jin Kim, Jung-Hoi Koo, Sun-Hong Song
Ann Rehabil Med 2013;37(2):208-214.   Published online April 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.2.208
Objective

To evaluate the short-term clinical effects of the intra-articular injection of botulinum toxin type A (BoNT-A) for the treatment of adhesive capsulitis.

Methods

A prospective, controlled trial compared the effects of intra-articular BoNT-A (Dysport; 200 IU, n=15) with the steroid triamcinolone acetate (TA; 20 mg, n=13) in patients suffering from adhesive capsulitis of the shoulder. All patients were evaluated using a Numeric Rating Scale (NRS) of the pain intensity and a measurement of the range of motion (ROM) at baseline (before treatment) and at 2, 4, and 8 weeks post-treatment.

Results

The NRS at 2 weeks (BoNT-A vs. TA; 5.0 vs. 5.2), 4 weeks (4.1 vs. 4.9) and 8 weeks (3.8 vs. 4.6) of both treatment groups were significantly lower than that measured at baseline (7.4 vs. 7.6). The ROM of patients' shoulders increased significantly from baseline in both treatment groups. There was no significant difference in the NRS of pain intensity or the ROM between the two groups. Reduction in the pain intensity score was maintained for 8 weeks post-injection in both groups. There were no significant adverse events in either treatment group.

Conclusion

The results suggest that there are no significant short-term differences between the intra-articular injections of BoNT-A and TA. Although BoNT-A has a high cost, it may be used as a safe alternative of TA to avoid the steroid-induced side effects or as a second-line agent, for patients who have failed to respond to the current treatments.

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    Peng Zheng, Yu Shi, Hang Qu, Meng lin Han, Zhi qiang Wang, Qing Zeng, Manxu Zheng, Tao Fan
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    Ahmed Alghamdi, Ali H Alyami, Raad M. M Althaqafi, Ahmed Alzeyadi, Faisal S Alrubaei, Almuhanad A Alyami , Mohamed S Singer, Abdulelah A Saati , Wasn T Alotaibi , Maha O Alsharif
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    Neal L. Millar, Adam Meakins, Filip Struyf, Elaine Willmore, Abigail L. Campbell, Paul D. Kirwan, Moeed Akbar, Laura Moore, Jonathan C. Ronquillo, George A. C. Murrell, Scott A. Rodeo
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    Byung Joo Lee, Donghwi Park
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    Nicole Blanshan, Hollis Krug
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    Ke-Vin Chang, Yi-Hsiang Chiu, Wei-Ting Wu, Po-Cheng Hsu, Levent Özçakar
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    Giulia Bellon, Andrea Venturin, Stefano Masiero, Alessandra Del Felice
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    Mathilde Courseau, Pascale Vergne Salle, Danièle Ranoux, Anais de Pouilly Lachatre
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    Helka M. Heikkilä, Tarja S. Jokinen, Pernilla Syrjä, Jouni Junnila, Anna Hielm-Björkman, Outi Laitinen-Vapaavuori, Louis S Premkumar
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