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Review Article

Pain & Musculoskeletal rehabilitation

Hand-Related Activities of Daily Living Challenges Among Individuals With Diabetic Peripheral Neuropathy: A Scoping Review
Noor Aziella Mohd Nayan, Chi-Wen Chien, Najihah Lokman, Mohammed Alrashdi, Ahmad Zamir Che Daud
Ann Rehabil Med 2025;49(3):139-151.   Published online June 19, 2025
DOI: https://doi.org/10.5535/arm.250003
Diabetic peripheral neuropathy (DPN), a common complication of type 2 diabetes mellitus, leads to sensory and motor impairments that significantly affect fine motor skills, grip strength, and dexterity, limiting daily functioning. Understanding the impact of DPN on hand-related activities of daily living (ADLs) is crucial for improving patient care and outcomes. This review employed the International Classification of Functioning, Disability, and Health (ICF) framework to assess hand function issues. A systematic search of peer-reviewed studies was conducted across multiple databases to identify research examining the impact of DPN on hand-related ADLs. The findings were categorised using relevant ICF codes linked to hand function issues. The analysis identified four major themes: (1) the impact of DPN on daily activities and participation; (2) sensory impairments affecting hand function; (3) muscle weakness and functional limitations; and (4) unaddressed areas, such as structural changes, driving, assisting others, and preparing meals. DPN was found to significantly hinder hand function, reducing independence in ADLs and overall quality of life. This review highlights the need for comprehensive assessments that address not only impairments, but also activity limitations and participation restrictions, to capture the multifaceted challenges of DPN. Developing targeted assessments tailored to the specific needs of individuals with DPN is essential for improving intervention strategies and overall quality of care.

Citations

Citations to this article as recorded by  
  • Prediction of diabetic peripheral neuropathy in type 2 diabetes using high-frequency ultrasound and shear-wave elastography of the median and tibial nerves: a nomogram study
    Kunbin Wu, Jiaying Wang, Wenting Jiang, Xiaohan Cai, Lu Huang, Boyu She, Menglu Song, Zhenhan Lai, Guorong Lyu
    European Journal of Medical Research.2026;[Epub]     CrossRef
  • Rehabilitation interventions for upper limb dysfunction in type 2 diabetes mellitus, with or without diabetic peripheral neuropathy: a systematic review and meta-analysis
    Noor Aziella Mohd Nayan, Mohammed Alrashdi, Hakim Zulkarnaen, Setho Hadisuyatmana, Hazliza Razali, Ahmad Zamir Che Daud
    Disability and Rehabilitation.2026; : 1.     CrossRef
  • Hand function in immune-mediated inflammatory rheumatic diseases: assessment and rehabilitation approaches
    Umida Khojakulova, Olena Zimba, Mariusz Korkosz, Burhan Fatih Kocyigit
    Rheumatology International.2025;[Epub]     CrossRef
  • 7,359 View
  • 171 Download
  • 3 Web of Science
  • 3 Crossref

Original Articles

Pain & Musculoskeletal rehabilitation

Efficacy and Safety of High Density LED Irradiation Therapy for Patients With Hand Osteoarthritis: A Single-Center Clinical Study
Kyungmin Kim, Sung Hoon Kim, Ji Hyun Kim, Sang Yeol Yong, Won Woo Choi, Sun Jung Kim, Hyuk Do Kim, Kyung Joon Oh, Dae Ryong Kang, Sehwa Hong, Jiseon Hong
Ann Rehabil Med 2024;48(1):50-56.   Published online December 12, 2023
DOI: https://doi.org/10.5535/arm.23127
Objective
To assess the safety and effectiveness of high-density light-emitting diode (LED) irradiation therapy in patients with hand osteoarthritis (OA) and compare the pre- and post-intervention symptoms.
Methods
Twenty-three patients with hand OA underwent eight sessions of high-density LED irradiation therapy directed at the five most painful areas in the finger joints. Each session lasted for 18 minutes; and the sessions were conducted twice a week, for 4 weeks. We evaluated the degree of pain using the visual analogue scale, ring size, and passive range of motion (flexion+extension) for two most painful joints from the baseline to post-therapy (weeks 4 and 6).
Results
High-density LED irradiation therapy significantly reduced the pain posttreatment compared with that observed at the baseline (p<0.001). Although improvements were observed in ring size and joint range of motion at 4 and 6 weeks, they were not statistically significant (p>0.05). No adverse events were observed.
Conclusion
We examined the safety and effectiveness of high-density LED irradiation therapy in reducing pain and hand swelling and improving joint mobility in patients with hand OA. These results suggest that high-density LED irradiation therapy has the potential to be an important strategy for managing hand OA.

Citations

Citations to this article as recorded by  
  • Letter to the Editor: Efficacy and Safety of High Density LED Irradiation Therapy for Patients With Hand Osteoarthritis: A Single-Center Clinical Study
    Vanshika Agarwal, Jeyanthi. S, Adarsh Sharma
    Annals of Rehabilitation Medicine.2025; 49(1): 1.     CrossRef
  • Response: Efficacy and Safety of High Density LED Irradiation Therapy for Patients With Hand Osteoarthritis: A Single-Center Clinical Study (Ann Rehabil Med 2024;48:50-6)
    Jiseon Hong
    Annals of Rehabilitation Medicine.2025; 49(1): 3.     CrossRef
  • Photobiomodulation Literature Watch December 2023
    James D. Carroll
    Photobiomodulation, Photomedicine, and Laser Surgery.2024; 42(10): 660.     CrossRef
  • 10,075 View
  • 136 Download
  • 2 Web of Science
  • 3 Crossref

Cardiopulmonary rehabilitation

Phase Angle Is Associated With Handgrip Strength in Older Patients With Heart Failure
Wataru Kawakami, Takuya Umehara, Yoshitaka Iwamoto, Makoto Takahashi, Nobuhisa Katayama
Ann Rehabil Med 2023;47(2):129-137.   Published online March 21, 2023
DOI: https://doi.org/10.5535/arm.22138
Objective
To assess the relationships between phase angle and muscle mass, strength, and physical function in patients with heart failure.
Methods
This study used a cross-sectional design. The analysis included 51 patients with heart failure. The Short Physical Performance Battery, one-leg standing time, handgrip strength, phase angle, and skeletal muscle index were measured. To identify explanatory variables of phase angle, hierarchical multiple regression analysis was performed.
Results
Handgrip strength was found to be an explanatory variable of phase angle independent of age, sex, and body mass index. This model was able to explain 30.4% of the model variance for phase angle.
Conclusion
In patients with heart failure, improving muscle strength rather than muscle mass or physical function might be more important for improving phase angle. Handgrip strength is an important outcome for improving prognosis in patients with heart failure.

Citations

Citations to this article as recorded by  
  • Phase Angle and Impedance Ratio as Indicators of Physical Function and Fear of Falling in Older Adult Women: Cross-Sectional Analysis
    Danielle A Sterner, Jeffrey R Stout, Kworweinski Lafontant, Joon-Hyuk Park, David H Fukuda, Ladda Thiamwong
    JMIR Aging.2024; 7: e53975.     CrossRef
  • Prevalence and clinical characteristics of Sarcopenia in older adult patients with stable chronic obstructive pulmonary disease: a cross-sectional and follow-up study
    Sang Hun Kim, Cho Hui Hong, Myung-Jun Shin, Ki Uk Kim, Tae Sung Park, Jun Yong Park, Yong Beom Shin
    BMC Pulmonary Medicine.2024;[Epub]     CrossRef
  • Malnutrition in Amyotrophic Lateral Sclerosis: Insights from Morphofunctional Assessment and Global Leadership Initiative on Malnutrition Criteria
    María Teresa Zarco-Martín, Carmen Freire, María Carmen Andreo-López, Socorro Leyva-Martínez, María Luisa Fernández-Soto
    Nutrients.2024; 16(16): 2625.     CrossRef
  • 9,938 View
  • 138 Download
  • 5 Web of Science
  • 3 Crossref

Pain & Musculoskeletal rehabilitation

Association Between Vitamin E and Handgrip Strength in the Korean General Population in KNHANES VII (2018)
Nodam Park, Soo A Kim, Kiyoung Oh, Yuntae Kim, Siha Park, Joon Yeop Kim, Namhun Heo
Ann Rehabil Med 2021;45(3):170-177.   Published online June 14, 2021
DOI: https://doi.org/10.5535/arm.21038
Objective
To investigate the association between vitamin E and handgrip strength (HGS) with multiple factors.
Methods
A total of 1,814 participants were included (822 men and 981 women) from the Korean subjects of the 7th Korea National Health and Nutrition Examination Survey in 2018. Data were analyzed using multiple logistic regression to determine the correlation between vitamin E and HGS with potential confounding factors.
Results
In the multiple logistic regression model, only the young age group (19–40 years) of men showed a positive relationship between vitamin E and HGS. However, in older age groups (41–80 years) of men and all age groups of women, there was no statistically significant result. After adjusting for confounding factors, young men showed higher vitamin E levels and higher HGS. Conversely, women and older age groups did not show significant results after adjusting for confounding factors.
Conclusion
In this study, the serum vitamin E level had a positive effect on HGS in young men (<40 years). Further research is needed on this topic regarding vitamin E intake and other objective measures.

Citations

Citations to this article as recorded by  
  • Role of Serum and Dietary Vitamins A and E in Pulmonary Function and Chronic Obstructive Pulmonary Disease: A Systematic Review
    Shabina Saifullah, Amna Ihsan, Syed Haris Ali Shah, Afshan Iftikhar, Muhammad Hassan Ali Khan, Naveed Pervez
    Pakistan Journal of Health Sciences.2025;[Epub]     CrossRef
  • Evaluation of personal water footprint components in Turkey: factors associated with obesity and food consumption
    Merve Şeyda Karaçil Ermumcu, Merve Esra Çıtar Dazıroğlu, Nazlıcan Erdoğan Gövez, Nilüfer Acar Tek
    International Journal of Environmental Health Research.2024; 34(1): 432.     CrossRef
  • Narrative Review of Sex Differences in Muscle Strength, Endurance, Activation, Size, Fiber Type, and Strength Training Participation Rates, Preferences, Motivations, Injuries, and Neuromuscular Adaptations
    James L. Nuzzo
    Journal of Strength & Conditioning Research.2023; 37(2): 494.     CrossRef
  • Effects of leucine-rich protein supplements in older adults with sarcopenia: A systematic review and meta-analysis of randomized controlled trials
    Sang Yoon Lee, Hyun Jeong Lee, Jae-Young Lim
    Archives of Gerontology and Geriatrics.2022; 102: 104758.     CrossRef
  • Handgrip Strength: An Irreplaceable Indicator of Muscle Function
    Sang Yoon Lee
    Annals of Rehabilitation Medicine.2021; 45(3): 167.     CrossRef
  • Folic Acid Is Related to Muscle Strength and Vitamin A Is Related to Health-Related Quality of Life: Results of the Korea National Health and Nutrition Examination Survey (KNHANES VII 2016–2018)
    Mee-Ri Lee, Sung Min Jung
    Nutrients.2021; 13(10): 3618.     CrossRef
  • 8,669 View
  • 167 Download
  • 5 Web of Science
  • 6 Crossref

Physical Therapy

Effect of Core Stability Exercises on Hand Functions in Children With Hemiplegic Cerebral Palsy
Hanaa Mohsen Abd-Elfattah, Sobhy Mahmoud Aly
Ann Rehabil Med 2021;45(1):71-78.   Published online February 9, 2021
DOI: https://doi.org/10.5535/arm.20124
Objective
To investigate the effectiveness of core stability exercises on hand functions in children with hemiplegic cerebral palsy.
Methods
Fifty-two children with hemiplegic cerebral palsy ranging in age from 6 years to 8 years were enrolled in this study. They were randomly assigned to two (control and study) groups. The control group received the selected physiotherapy exercises, and the study group received the same selected physiotherapy exercise program and core stability exercises. Time motor performance, gross manual dexterity, and upper extremity skills assessed using the Jebsen Taylor Hand Function Test, Box and Block Test, and Quality Upper Extremity Skill Test, respectively, were measured before and after 12 weeks of the treatment program.
Results
There were significant improvements in both groups by comparing the mean values of all measured variables before and after treatment (p<0.05). There were significant differences between the control and study groups with respect to all measured variables when comparing the post-treatment outcomes (p<0.05).
Conclusion
This study suggests that core stability exercises can be an effective intervention that may improve hand functions in children with hemiplegic cerebral palsy.

Citations

Citations to this article as recorded by  
  • Comparison of Trunk Control and Upper Limb Function in Children with Spastic Cerebral Palsy: A Cross-Sectional Observational Study
    Seema V. Lad, Dhwanit S. Shah
    International Journal of Health Sciences and Research.2026; : 76.     CrossRef
  • A self-made suspension trainer as a tool for core muscle activation and motivation in a girl with cognitive and motor impairments: a case report
    Volodymyr Maksym
    Frontiers in Rehabilitation Sciences.2026;[Epub]     CrossRef
  • Effect of core stability exercises on upper limb reaching in children with spastic hemiparetic cerebral palsy: a randomized controlled trial
    Nadia Hassan Abd-Elhameed, Heballah Mohammed Kamal, Mai Elsayed Abbass
    Bulletin of Faculty of Physical Therapy.2025;[Epub]     CrossRef
  • A protocol to evaluate the effect of Modified Scooter Board Therapy on Trunk Control and Hip muscles Activation in children with Cerebral Palsy
    Shreekanth D. Karnad, Amitesh Narayan, Nutan Kamath, Bhamini K. Rao, Monika Sharma, Vijaya Kumar K
    MethodsX.2025; 14: 103301.     CrossRef
  • The Effect of Core Stabilization Exercises on Upper Extremity Function and Balance in Children with Cerebral Palsy: A Randomized Controlled Trial
    Kübra Ecem Küçük, Cigdem Cekmece
    Healthcare.2025; 13(12): 1454.     CrossRef
  • Ethical issues in Iranian pediatrics: a qualitative study
    Maryam Modabber, Shabnam Bazmi, Leila Masoudiyekta, Mina Forouzandeh
    BMC Medical Ethics.2025;[Epub]     CrossRef
  • Effects of Upper Limb Children Action-Observation Training (UP-CAT) with and without visual feedback in children with cerebral palsy
    Iqra Iqra, Samra Anwar, Faria Riaz, Sarah Khalid
    International journal of health sciences.2025; 9(S1): 643.     CrossRef
  • Effective of Core Muscles Exercises and Proprioceptive Exercises on Balance and Functional Mobility in Children with Cerebral Palsy- A Comparative Study
    Samiya Shaikh, Abhijit Satralkar, Sucheta Golhar
    International Journal of Innovative Science and Research Technology (IJISRT).2024; : 912.     CrossRef
  • Acute effect of single-session physio-ball wall squat training on knee active reposition sense and isokinetic parameters in sedentary female collegiate students: an experimental study
    Mariam Ameer, Ammar Al Abbad, Arun Subbarayalu, Heba Bahey El- Deen, Shahad AL Sirhani, Elaf AL Arjan, Wessam ALIhawy, Njoud AL Ruwaili, Mohamed Kamel
    Human Movement.2024; 25(3): 109.     CrossRef
  • Effects of abdominal muscle strengthening and pelvic control exercises on trunk control and pelvic movement in children with unilateral cerebral palsy
    Sun-Young Ha, Yong-Hun Kim, Yun-Hee Sung
    Journal of Exercise Rehabilitation.2024; 20(6): 250.     CrossRef
  • What Is the Relationship between Trunk Control Function and Arm Coordination in Adults with Severe-to-Moderate Quadriplegic Cerebral Palsy?
    María Isabel Cornejo, Alba Roldan, Raul Reina
    International Journal of Environmental Research and Public Health.2022; 20(1): 141.     CrossRef
  • 14,254 View
  • 387 Download
  • 9 Web of Science
  • 11 Crossref
Effect of Decreased Skeletal Muscle Index and Hand Grip Strength on Functional Recovery in Subacute Ambulatory Stroke Patients
Jin Gee Park, Kyeong Woo Lee, Sang Beom Kim, Jong Hwa Lee, Young Hwan Kim
Ann Rehabil Med 2019;43(5):535-543.   Published online October 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.5.535
Objective
To investigate the effect of decreased Skeletal Muscle Index (SMI) and hand grip strength on functional recovery in subacute ambulatory stroke patients.
Methods
Subacute stroke patients who were referred to the rehabilitation center were recruited. Decreased SMI and hand grip strength were diagnosed according to the Asian Working Group on Sarcopenia. Diagnostic criteria were decreased SMI and decreased unaffected hand grip strength. SMI was measured by bioelectrical impedance analysis. Unaffected hand grip strength was measured with a hand dynamometer. Patients were divided into two groups, decreased group (DG) and not-decreased group (NDG), according to the presence of decreased SMI and hand grip strength. Both groups received conventional stroke rehabilitation for 3 weeks. All patients were evaluated at the baseline and at 3 weeks after treatment. Functional status was evaluated with 4-meter walk test (4MWT), 6-minute walk test (6MWT), Timed Up and Go test (TUG), and Modified Barthel Index (MBI).
Results
Both groups showed improvement in 4MWT, TUG, and MBI. NDG showed improvement in 6MWT. Comparing improvements between the two groups, NDG showed more improvement in 6MWT and TUG than DG.
Conclusion
The presence of decreased SMI and hand grip strength had negative effects on functional recovery in subacute ambulatory stroke patients.

Citations

Citations to this article as recorded by  
  • Prevalence of Stroke‐Related Sarcopenia: A Systematic Review and Meta‐Analysis
    Lavinia Pereira dos Santos, Bruna Machado Staico, Anna Balsamão Vaz, Ana Carolina Joviano Galvão, Ana Luiza Miranda de Oliveira, Maria Clara Ferreira, Amanda Leopoldino, Janaíne Cunha Polese
    Physiotherapy Research International.2026;[Epub]     CrossRef
  • Optimized transcranial direct current stimulation for post-stroke dysphagia with small electrodes: a double-blind, randomized, feasibility study protocol
    TaeYeong Kim, Hae-Yeon Park, Sung-Hwa Ko, Yeun Jie Yoo, Hanna Jang, Hyun Mi Oh, Mi-Jeong Yoon, Geun-Young Park, Donghyeon Kim, Tae-Woo Kim, Sun Im
    Frontiers in Neurology.2026;[Epub]     CrossRef
  • Validity and Reliability of the InGrip® Load-Cell Handgrip Dynamometer Compared With the Takei Handgrip Dynamometer in Healthy Adults and Patients With Stroke
    Byung Joo Lee, Hyeon-Taek Hong, Ga Hui Yu, Kyoung Tae Kim
    Journal of Korean Medical Science.2026;[Epub]     CrossRef
  • Usefulness of body composition assessment by bioelectrical impedance vector analysis in subacute post-stroke patients in rehabilitation
    Alessandro Guerrini, Mariacristina Siotto, Carola Cocco, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Stefania Lattanzi, Sabina Insalaco, Yeganeh Manon Khazrai, Irene Giovanna Aprile
    Scientific Reports.2025;[Epub]     CrossRef
  • Prevalence and Clinical Implications of Osteosarcopenia in Patients With Acute Stroke
    Kyoung Tae Kim, Soyoung Lee, Jang Hyuk Cho, Yongmin Choi
    American Journal of Physical Medicine & Rehabilitation.2025; 104(2): 101.     CrossRef
  • Clinical Significance of Sarcopenia Defined by the Cross-Sectional Area of the Masseter Muscle in Cerebrovascular Events: A Retrospective Cohort Study
    Fatih Seğmen, Semih Aydemir, Temel Kayan, Firdevs Tuğba Bozkurt Biçer, Cihangir Doğu, Esra Yakışık Aktekin, Deniz Erdem, Elif Uzun Ata
    Medicina.2025; 61(2): 268.     CrossRef
  • Eating difficulties among Nigerian community-dwelling stroke survivors: prevalence, correlates, and association with quality of life
    Adekola B. Ademoyegun, Adebukola G. Ibitoye, Wasiu A. Rasaq, Oluwafunmilayo A. Adeniyi, David O. Fabuluje, Israel A. Ojo, Taofeek O. Awotidebe, Chidozie E. Mbada
    BMC Public Health.2025;[Epub]     CrossRef
  • Role of sarcopenia in Temporal progression trajectory of cardiometabolic diseases: a prospective study in UK biobank
    Yi Xiao, Chen Zhu, Xunjie Cheng, Qun Huang, Tianqi Ma, Yongping Bai
    BMC Public Health.2025;[Epub]     CrossRef
  • Phase angle is a predictor of functional outcomes at discharge in patients with acute ischemic stroke
    Hiroshi Ohmae, Shin Kondo, Takashi Saito, Wataru Sano, Yuka Sugiyama, Ayane Tomari, Motomu Kamada, Yuka Nakanowatari, Maki Fujimoto, Megumi Yamada, Nori Sato, Kimiko Umemura, Ryoma Morigaki, Yasushi Takagi, Tetsuya Matsuura
    The Journal of Medical Investigation.2025; 72(1.2): 148.     CrossRef
  • Combined Effect of tDCS and GRASP for Upper Limb Rehabilitation in Stroke: A Clinical and Accelerometric Pilot Study
    Erica Grange, Rachele Di Giovanni, Fabio Giuseppe Masuccio, Virginia Tipa, Luca Dileo, Alessandra Bordino, Micaela Porta, Bruno Leban, Martina Rolla, Massimiliano Pau, Claudio Marcello Solaro
    Sensors.2025; 25(16): 4907.     CrossRef
  • The relationship between stroke-related sarcopenia and 3-month neurological outcome in stroke patients: a prospective cohort study
    Aiguo Zhang, Sunwen You, Jianning Xia, Xiangzhi Shao, Xinyu Pu, Jiacheng Zhang, Xinming Wu, Jinyihui Zheng, Dengchong Wu, Bing Chen, Lielie Zhu
    BMC Geriatrics.2025;[Epub]     CrossRef
  • Detection of skeletal muscle loss using ultrasound and its association with the plasma C-terminal agrin fragment biomarker in acute ischemic stroke patients in the neurological intensive care unit
    Nesibe Büşra Fidantek, Eşref Akıl, Ayfer Ertekin, Hamza Gültekin, Aysun Ekinci, Mehmet Uğur Çevik, Mehmet Ufuk Aluçlu
    Clinical Science of Nutrition.2025; 7(3): 169.     CrossRef
  • Impact of sarcopenia on functional and cognitive recovery in Caucasian post-stroke patients following rehabilitation
    Alessandro Guerrini, Mariacristina Siotto, Alessio Fasano, Carola Cocco, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Stefania Lattanzi, Sabina Insalaco, Erika Antonacci, Elisabetta Ruco, Yeganeh Manon Khazrai, Irene Giovanna Apri
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Risk prediction models for post-stroke sarcopenia: A systematic review and appraisal
    Ting Wu, Hui Si, Weixiang Luo, Sijia Zhou, Julan Xiao, Xiufen Yang
    Cure & Care.2025; 1(2): 100025.     CrossRef
  • Development and Evaluation of a Mobile Application to Prevent Recurrent Stroke by Enhancing Self-management on Health Outcomes for Stroke Survivors
    Young Ju Jeong, Hee Sun Kim, Hyun Goo Kang
    CIN: Computers, Informatics, Nursing.2024; 42(1): 53.     CrossRef
  • Muscle quality improvement in subacute post-stroke patients after rehabilitation: Usefulness of segmental phase angle from bioelectrical impedance analysis
    Alessandro Guerrini, Mariacristina Siotto, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Sabina Insalaco, Yeganeh Manon Khazrai, Irene Aprile
    Clinical Nutrition.2024; 43(1): 224.     CrossRef
  • Exploratory analysis using machine learning algorithms to predict pinch strength by anthropometric and socio-demographic features
    Sajjad Rostamzadeh, Alireza Abouhossein, Khurshid Alam, Shahram Vosoughi, Seyedeh Sousan Sattari
    International Journal of Occupational Safety and Ergonomics.2024; 30(2): 518.     CrossRef
  • Hydroxytyrosol, a Promising Supplement in the Management of Human Stroke: An Exploratory Study
    Ángela Naranjo, M. Josefa Álvarez-Soria, Pilar Aranda-Villalobos, Ana M. Martínez-Rodríguez, Esther Martínez-Lara, Eva Siles
    International Journal of Molecular Sciences.2024; 25(9): 4799.     CrossRef
  • Association of Characteristics between Acute Stroke Patients and Sarcopenia: A Cross-Sectional Study
    So-Yeong Kim, Byeong-Geun Kim, Se-Ju Park
    Exercise Science.2024; 33(2): 216.     CrossRef
  • Sex difference, proteostasis and mitochondrial function impact stroke-related sarcopenia—A systematic review and meta-analysis
    Chien-Yu Huang, Yu-Huei Liu
    Ageing Research Reviews.2024; 101: 102484.     CrossRef
  • Effect of Sarcopenia on Functional Recovery in Acute Stroke Patients Admitted for Standard Rehabilitation Program
    So-Yeong Kim, Woon-Su Cho, Chi-Bok Park, Byeong-Geun Kim
    Medicina.2024; 60(10): 1716.     CrossRef
  • Effects of muscle strength exercise on muscle mass and muscle strength in patients with stroke: a systematic review and meta-analysis
    Ah-Young Choi, Jae-Hyun Lim, Byeong-Geun Kim
    Journal of Exercise Rehabilitation.2024; 20(5): 146.     CrossRef
  • Prevalence and risk factors of sarcopenia in patients with stroke: a systematic review and meta-analysis
    Xiang He, Xiping Shen, Tingting Yang, Guifen Ma, Jinhan Nan, Juanjuan Feng, Fanghong Yan, Cuilian Wang, Lin Han, Yanan Zhang, Yuxia Ma
    Neurosurgical Review.2024;[Epub]     CrossRef
  • Body Cell Mass from Bioelectrical Impedance Analysis in Patients with Stroke Undergoing Rehabilitation
    Alessandro Guerrini, Mariacristina Siotto, Marco Germanotta, Mirko Schirru, Arianna Pavan, Valeria Cipollini, Sabina Insalaco, Irene Aprile
    Applied Sciences.2023; 13(6): 3965.     CrossRef
  • Impact of skeletal muscle mass on functional prognosis in acute stroke: A cohort study
    Keisuke Honma, Yosuke Honda, Masahiro Nagase, Yuta Nakao, Tetsuya Harada, Naoki Sasanuma, Yuki Uchiyama, Norihiko Kodama, Kazuhisa Domen
    Journal of Clinical Neuroscience.2023; 112: 43.     CrossRef
  • Sarcopenia in patients following stroke: Prevalence and associated factors
    Rio Ikeji, Masafumi Nozoe, Miho Yamamoto, Haruka Seike, Hiroki Kubo, Shinichi Shimada
    Clinical Neurology and Neurosurgery.2023; 233: 107910.     CrossRef
  • Comparison of two handgrip dynamometers in older adults before elective surgery
    Maricarmen S. Andrade, Macarena P. Honorato, Javiera P. Vargas, María de los Angeles Galvez, Mariana R. Rojas
    Perioperative Medicine.2023;[Epub]     CrossRef
  • Association Between Skeletal Muscle Mass Index and Falls in Patients With Functional Impairment
    Hideki Arai, Masafumi Nozoe, Kuniyasu Kamiya, Satoru Matsumoto, Takeshi Morimoto
    American Journal of Physical Medicine & Rehabilitation.2023; 102(10): 913.     CrossRef
  • Impact of Sarcopenia on Functional Outcomes Among Patients With Mild Acute Ischemic Stroke and Transient Ischemic Attack: A Retrospective Study
    Hyungwoo Lee, Il Hyung Lee, JoonNyung Heo, Minyoul Baik, Hyungjong Park, Hye Sun Lee, Hyo Suk Nam, Young Dae Kim
    Frontiers in Neurology.2022;[Epub]     CrossRef
  • Effect of combined locomotor training and aerobic exercise on increasing handgrip strength in elderly with locomotive syndrome: A randomised controlled trial
    Ajeng Hayu Nayasista, Damayanti Tinduh, Putu I Alit Pawana, Sri Mardjiati Mei Wulan, Dwikora Novembri Utomo, Melaniani Soenarnatalina
    Annals of Medicine & Surgery.2022;[Epub]     CrossRef
  • Possible Sarcopenia and Its Association with Nutritional Status, Dietary Intakes, Physical Activity and Health-Related Quality of Life among Older Stroke Survivors
    Hui Jie Wong, Sakinah Harith, Pei Lin Lua, Khairul Azmi Ibrahim
    Annals of Geriatric Medicine and Research.2022; 26(2): 162.     CrossRef
  • Predictive ability of hand-grip strength and muscle mass on functional prognosis in patients rehabilitating from stroke
    Tatsuya Matsushita, Shinta Nishioka, Anna Yamanouchi, Yuka Okazaki, Kana Oishi, Ryusei Nakashima, Yoshiharu Tokunaga, Shinya Onizuka
    Nutrition.2022; 102: 111724.     CrossRef
  • Sarcopenia and nervous system disorders
    Jie Yang, Feifei Jiang, Ming Yang, Zhizhi Chen
    Journal of Neurology.2022; 269(11): 5787.     CrossRef
  • Does grip strength of the less-affected side of ischemic stroke survivors influences performance of self-care activities?
    Adekola Babatunde Ademoyegun, Chidozie Emmanuel Mbada, Oluwatobi Ademola Sonuga, Oluwatobi Elijah Malomo, Wasiu Abiodun Fatai, Ishanosen Abidemi Aghedo
    Bulletin of Faculty of Physical Therapy.2022;[Epub]     CrossRef
  • Aging after stroke: how to define post-stroke sarcopenia and what are its risk factors?
    Sheng LI, Javier GONZALEZ-BUONOMO, Jaskiran GHUMAN, Xinran HUANG, Aila MALIK, Nuray YOZBATIRAN, Elaine MAGAT, Gerard E. FRANCISCO, Hulin WU, Walter R. FRONTERA
    European Journal of Physical and Rehabilitation Medicine.2022;[Epub]     CrossRef
  • Relationship between Nutritional Status, Food Consumption and Sarcopenia in Post-Stroke Rehabilitation: Preliminary Data
    Mariacristina Siotto, Marco Germanotta, Alessandro Guerrini, Simona Pascali, Valeria Cipollini, Laura Cortellini, Elisabetta Ruco, Yeganeh Manon Khazrai, Laura De Gara, Irene Aprile
    Nutrients.2022; 14(22): 4825.     CrossRef
  • Stroke-Related Sarcopenia among Two Different Developing Countries with Diverse Ethnic Backgrounds (Cross-National Study in Egypt and China)
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Sleep Quality and Attention May Correlate With Hand Grip Strength: FARM Study
Gyuhyun Lee, Sora Baek, Hee-won Park, Eun Kyoung Kang
Ann Rehabil Med 2018;42(6):822-832.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.822
Objective
To determine the socio-demographic, psychologic, hematologic, or other relevant factors associated with hand grip strength in Korean farmers.
Methods
A total of 528 healthy Korean farmers were enrolled. Hand grip strength was measured in both hands using a hydraulic dynamometer. Socio-demographic characteristics were assessed and anthropometric measurements were obtained. Psycho-cognitive measurements such as sleep quality (Pittsburgh Sleep Quality Index) and Go/No-Go test response time were conducted. In addition to physical measurements, serologic parameters including insulin-like growth factor 1 were measured. The factors associated with hand grip strength were analyzed using multiple linear regression analysis after adjusting for age, height, and weight.
Results
The mean hand grip strength was associated with the Pittsburgh Sleep Quality Index total score (β=-0.12, p=0.01), the Go/No-Go test response time (β=-0.18, p=0.001), vitamin D (β=0.12, p=0.02), and insulin-like growth factor 1 levels (β=0.1, p=0.045). In female farmers, hand grip strength was only associated with the Pittsburgh Sleep Quality Index total score (β=-0.32, p<0.001).
Conclusion
The results of this study demonstrate that hand grip strength was associated with sleep quality and attention in Korean farmers.

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    Antonina Kaczorowska, Sławomir Kozieł, Zofia Ignasiak
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  • Protein Intake and Diet Quality Mediate the Relationship Between Sleep and Handgrip Strength in Adults in the HANDLS Study
    Marie Fanelli Kuczmarski, Elizabeth Orsega-Smith, May A. Beydoun, Michele K. Evans, Alan B. Zonderman
    Nutrients.2025; 17(11): 1900.     CrossRef
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    Xin Xiong, Yinchen Cui, Weinan Zhang, Chenlin Zhao, Jiahui Wu, Haifeng Li, Zhiping Zhen, Jian Sun
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The Persisted Effects of Low-Frequency Repetitive Transcranial Magnetic Stimulation to Augment Task-Specific Induced Hand Recovery Following Subacute Stroke: Extended Study
Jarugool Tretriluxana, Jenjira Thanakamchokchai, Chutima Jalayondeja, Narawut Pakaprot, Suradej Tretriluxana
Ann Rehabil Med 2018;42(6):777-787.   Published online December 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.6.777
Objective
To examine the long-term effects of the low-frequency repetitive transcranial magnetic stimulation (LFrTMS) combined with task-specific training on paretic hand function following subacute stroke.
Methods
Sixteen participants were randomly selected and grouped into two: the experimental group (real LFrTMS) and the control group (sham LF-rTMS). All the 16 participants were then taken through a 1-hour taskspecific training of the paretic hand. The corticospinal excitability (motor evoke potential [MEP] amplitude) of the non-lesioned hemisphere, and the paretic hand performance (Wolf Motor Function Test total movement time [WMFT-TMT]) were evaluated at baseline, after the LF-rTMS, immediately after task-specific training, 1 and 2 weeks after the training.
Results
Groups comparisons showed a significant difference in the MEP after LF-rTMS and after the training. Compared to the baseline, the MEP of the experimental group significantly decreased after LF-rTMS and after the training and that effect was maintained for 2 weeks. Group comparisons showed significant difference in WMFT-TMT after the training. Only in the experimental group, the WMFT-TMT of the can lifting item significantly reduced compared to the baseline and the effect was sustained for 2 weeks.
Conclusion
The results of this study established that the improvement in paretic hand after task-specific training was enhanced by LF-rTMS and it persisted for at least 2 weeks.

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  • High-frequency rTMS and home-based exercise in individuals with Parkinson’s disease: A double-blind randomized controlled trial
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    Afifa Safdar, Marie-Claire Smith, Winston D. Byblow, Cathy M. Stinear
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Validity of the Buttoning Test in Hand Disability Evaluation of Patients With Stroke
Youn-Soo Cheong, Ae Ryoung Kim, Eunhee Park, Won-Jong Yang, Jae-Won Huh, Hyun-Min Oh, Yu-Sun Min, Chul-Hyun Kim, Tae-Du Jung, Yang-Soo Lee
Ann Rehabil Med 2018;42(1):18-25.   Published online February 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.1.18
Objective

To investigate the relationship between the buttoning test and Jebsen-Taylor Hand Function Test (JTHFT), and to determine the validity of using the buttoning test as a tool to evaluate hand disability in patients with stroke.

Methods

This was a retrospective study of the medical records of 151 ischemic stroke patients affecting the dominant hand. Patients underwent the buttoning test and JTHFT for their affected hand. All patients were divided into three groups depending on how quickly they fastened a button (group A, not completed; group B, slowly completed over 18 seconds; and group C, completed within 18 seconds).

Results

The button fastening time was negatively correlated with the total score and subtest scores of the JTHFT. Patients who experienced difficulty during the buttoning test had lower mean scores in the JTHFT (group A, 28.0±23.9; group B, 62.9±21.7; group C, 75.4±13.3; p<0.0001, Jonckheere-Terpstra test). We observed significant differences in JTHFT scores among the three groups (p<0.017, Mann-Whitney U-test), although there were considerable overlaps in JTHFT scores between the groups. Significant differences were also found in the subtest scores of the JTHFT, which include fine hand motor function (writing letters, p=0.009; moving small objects, p=0.003; stacking checkers, p=0.001 between groups B and C), among the three groups.

Conclusion

Considering its relationship with the JTHFT and validity, the buttoning test can be considered appropriate for evaluation of hand disability in patients with stroke.

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    Nadinne Roman, Cozmin Baseanu, Vlad Ionut Tuchel, Cristina Nicolau, Angela Repanovici, Adina Manaila, Diana Minzatanu, Roxana Steliana Miclaus
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    Alessandra Angelucci, Marco Damiani, Andrea Aliverti, Marina Scarlato
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    Alessandra Angelucci, Andrea Tettamanti, Elisabetta Sarasso, Massimo Filippi, Andrea Aliverti, Marina Scarlato, Inmaculada Riquelme
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  • Evaluation of Motor Function Rehabilitation for Stroke Patients Based on Magnetic Resonance DTI Technology
    Jie Kang, Dongyang Wang, Yongchang Duan, Aixu Chu, Di Wang
    IEEE Access.2020; 8: 77850.     CrossRef
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Relationship Between Grip and Pinch Strength and Activities of Daily Living in Stroke Patients
Jung Hyun Bae, Si Hyun Kang, Kyung Mook Seo, Don-Kyu Kim, Hyun Iee Shin, Hye Eun Shin
Ann Rehabil Med 2015;39(5):752-762.   Published online October 26, 2015
DOI: https://doi.org/10.5535/arm.2015.39.5.752
Objective

To investigate the relationship between grip and pinch strength and independence in activities of daily living (ADL) in stroke patients.

Methods

Medical records of 577 stroke patients from January 2010 to February 2013 were retrospectively reviewed. Patients' grip and pinch strength of both hemiplegic and non-hemiplegic hands and the Korean version of Modified Barthel Index (K-MBI) score were collected. These patients were divided into three groups: group A (onset duration: ≤3 months), group B (onset duration: >3 months and <2 years), and group C (onset duration: ≥2 years). The correlation between grip and pinch strength and the K-MBI score was analyzed.

Results

In group A (95 patients), the K-MBI score was significantly (p<0.05) correlated with the grip and pinch strength of both hands in patients with right hemiplegia. Significant (p<0.05) correlation between the K-MBI score and the grip and pinch strength of the hemiplegic hand was shown in patients with left hemiplegia. In group B (69 patients) and group C (73 patients), the K-MBI score was significantly (p<0.05) correlated with the grip and pinch strength of the hemiplegic hand.

Conclusion

Stroke patients in subacute stage mainly performed activities of daily living using their dominant hand. However, independence in ADL was associated with the strength of the affected dominant hand. For stroke patients in chronic and late chronic stages, their hand power of the affected hand was associated with independence in ADL regardless whether the dominant hand was affected.

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Handwriting Rehabilitation in Parkinson Disease: A Pilot Study
Adriana Ziliotto, Maria G. Cersosimo, Federico E. Micheli
Ann Rehabil Med 2015;39(4):586-591.   Published online August 25, 2015
DOI: https://doi.org/10.5535/arm.2015.39.4.586
Objective

To assess the utility of handwriting rehabilitation (HR) in Parkinson disease (PD) patients who experienced difficulties with handwriting and signing.

Methods

Sixty PD patients were prospectively studied with graphological evaluations. Thirty PD patients were assigned to HR for 9 weeks. At the end of this training, all patients were evaluated again and results of basal vs. final evaluations were compared.

Results

At final evaluation, the group assigned to HR showed significantly larger amplitude of the first 'e' in the phrase, larger signature surface area, and superior margin. A trend of increase in letter size was also observed. Handwriting with progressively decreasing size of letters and ascending direction with respect to the horizontal were prominent findings in both groups of patients and they did not change after HR.

Conclusion

Rehabilitation programs for handwriting problems in PD patients are likely to be helpful. Larger randomized studies are needed to confirm these results.

Citations

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The Relationship Between Sleep Disturbance and Functional Status in Mild Stroke Patients
Jinil Kim, Yuntae Kim, Kwang Ik Yang, Doh-eui Kim, Soo A Kim
Ann Rehabil Med 2015;39(4):545-552.   Published online August 25, 2015
DOI: https://doi.org/10.5535/arm.2015.39.4.545
Objective

To investigate the sleep state of mild stroke patients and relationship between sleep disturbance and functional status.

Methods

A total of 80 acute stroke patients were enrolled in this study. The criteria for inclusion in the study was as following: 1) first stroke, 2) cognitive function preserved enough to perform the test (Mini Mental State Examination ≥24), 3) good functional levels (Modified Rankin Scale ≤3), 4) upper extremity motor function preserved enough to perform occupational tests (hand strength test, Purdue pegboard test, 9-hole peg test, and Medical Research Council score ≥3), and 5) less than 2 weeks between the stroke and the assessment. Quality of sleep was assessed by using Pittsburg Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), and Stanford Sleepiness Scale (SSS). Activities of daily living was assessed by using the Modified Barthel Index (MBI) and depressed mood was assessed by using the Beck Depression Inventory (BDI). Gross and fine motor function of the upper extremity was assessed by using hand strength test (Jamar dynamometer), Purdue pegboard test, and the 9-hole peg test.

Results

The results of the occupational assessment were fine in the good sleepers. The PSQI, ESS, and ISI were correlated with some of the assessment tools (BDI, MBI, Purdue pegboard, 9-hole peg, and hand strength).

Conclusion

In conclusion, this study emphasizes that sleep disturbance can affect the functional status in mild acute stroke patients. Therefore, clinicians must consider sleep status in stroke patients and need to work to control it.

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Objective

To compare the effect of two different hand exercises on hand strength and vascular maturation in patients who underwent arteriovenous fistula surgery.

Methods

We recruited 18 patients who had chronic kidney disease and had undergone arteriovenous fistula surgery for hemodialysis. After the surgery, 10 subjects performed hand-squeezing exercise with GD Grip, and other 8 subjects used Soft Ball. The subjects continued the exercises for 4 weeks. The hand grip strength, pinch strength (tip, palmar and lateral pinch), and forearm circumference of the subjects were assessed before and after the hand-squeezing exercise. The cephalic vein size, blood flow velocity and volume were also measured by ultrasonography in the operated limb.

Results

All of the 3 types of pinch strengths, grip strength, and forearm circumference were significantly increased in the group using GD Grip. Cephalic vein size and blood flow volume were also significantly increased. However, blood flow velocity showed no difference after the exercise. The group using Soft Ball showed a significant increase in the tip and lateral pinch strength and forearm circumference. The cephalic vein size and blood flow volume were also significantly increased. On comparing the effect of the two different hand exercises, hand-squeezing exercise with GD Grip had a significantly better effect on the tip and palmar pinch strength than hand-squeezing exercise with Soft Ball. The effect on cephalic vein size was not significantly different between the two groups.

Conclusion

The results showed that hand squeezing exercise with GD Grip was more effective in increasing the tip and palmar pinch strength compared to hand squeezing exercise with soft ball.

Citations

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Short-Term Change of Handgrip Strength After Trigger Point Injection in Women With Muscular Pain in the Upper Extremities
Soo Jin Lee, Dong Heun Ahn, Ji Hun Jung, Yong Rok Kim, Young Jin Lee
Ann Rehabil Med 2014;38(2):241-248.   Published online April 29, 2014
DOI: https://doi.org/10.5535/arm.2014.38.2.241
Objective

To determine overall handgrip strength (HGS), we assessed the short-term change of HGS after trigger point injection (TPI) in women with muscular pain in the upper extremities by comparison with established pain scales.

Methods

The study enrolled 50 female patients (FMS with MPS group: 29 patients with combined fibromyalgia [FMS] and myofascial pain syndrome [MPS]; MPS group: 21 patients with MPS) who presented with muscular pain in the upper extremities at Konyang University Hospital. In addition, a total of 9 healthy women (control group) were prospectively enrolled in the study. We surveyed the three groups using the following established pain scales: the Fibromyalgia Impact Questionnaire (FIQ), the 36-Item Short Form Health Survey (SF-36), and the Short Form McGill Pain Questionnaire (MPQ). HGS was measured in both hands of study participants using a handgrip dynamometer. We performed TPI (0.5% lidocaine, total 10 mL, injected at the pain site of upper extremities). After 20 minutes, we remeasured the patient's HGS and MPQ score.

Results

ANOVA analysis was conducted among groups. Based on Tukey multiple comparison test, the majority of FIQ and SF-36 subscales, total FIQ and SF-36 scores, MPQ and HGS were significantly different between FMS with MPS and the other groups. There was no statistically significant difference between MPS and control groups. Higher HGS was positively associated with enhanced physical function, negatively associated with total FIQ and MPQ scores, and positively associated with the total SF-36 score calculated using Spearman correlation. Post-TPI MPQ decreased and HGS increased. In patient groups, a negative correlation was found between MPQ and HGS.

Conclusion

The HGS test might potentially be a complementary tool in assessing the short-term treatment effects of women with muscular pain in the upper extremities.

Citations

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Case Report

Stepwise Rehabilitation of the Triple Amputee Combined With Dysfunction of the Sound Limb
Ji Cheol Shin, Hye Eun Yang, Su Jin Yu, Na Young Kim, Seo Yeon Yoon
Ann Rehabil Med 2014;38(1):116-121.   Published online February 25, 2014
DOI: https://doi.org/10.5535/arm.2014.38.1.116

To find a multiple amputee more severe than a triple amputee is not easy. This is a report of a 36-year-old patient with right knee disarticulation, left trans-femoral amputation and right elbow disarticulation due to peripheral ischemic necrosis, when he was applied vasopressor in septic shock condition. His left hand was also 2nd, 3rd, 4th, and 5th distal interphalangeal joint disarticulation status, and it was more difficult for him to do rehabilitation program, such as donning and doffing the prostheses. For more efficient rehabilitation training program, we first focused on upper extremities function, since we believed that he might need a walking aid for gait training later. After 13 weeks of rehabilitation program, he has become sit to stand and walk short distance independently with an anterior walker. Although he still needs some assistance with activities of daily living, his Functional Independence Measure score improved from 48 to 90 during the course of 13 weeks.

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Original Articles

Generalized Joint Hypermobility in Healthy Female Koreans: Prevalence and Age-Related Differences
Ji-Won Kwon, Won-Jae Lee, Si-Bog Park, Mi Jung Kim, Seong Ho Jang, Chang Kweon Choi
Ann Rehabil Med 2013;37(6):832-838.   Published online December 23, 2013
DOI: https://doi.org/10.5535/arm.2013.37.6.832
Objective

Objective To evaluate the prevalence of generalized joint hypermobility (GJH) in healthy female Koreans and to determine whether the degree of GJH differs between children and adults.

Methods

Two groups of females were enrolled, a group of girls from an elementary school (n=404) and women from a call center (n=266). GJH was diagnosed using the Beighton score, which is composed of an evaluation of bilateral knees, elbows, thumbs, and fifth fingers as well as thoracolumbar joint. The GJH and localized hypermobility of each joint was compared between the two groups, and the pattern of hypermobility according to age and dominant hand was investigated.

Results

Total prevalence of GJH was 50.0% (335/750), and it was more frequently observed in the group of girls (58.9%, 238/404) than women (36.5%, 97/266). The degree of GJH expressed in terms of Beighton score was inversely correlated with age (p<0.05). Significant differences in localized hypermobility of the thumb and fifth finger were found between the two groups and were postulated as the cause for the decline in GJH with age. The pattern of decreased mobility proportional to aging differed between the two joints. Decreased mobility occurred equally on both sides of the thumb but was biased toward the fifth finger of the dominant side (mostly the right).

Conclusion

The female Koreans appeared to have a high prevalence of GJH. The incidence of GJH decreased as age increased as a result of decreased mobility of the fifth finger on the dominant side.

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The Effect of a Hand-Stretching Device During the Management of Spasticity in Chronic Hemiparetic Stroke Patients
Eun Hyuk Kim, Min Cheol Jang, Jeong Pyo Seo, Sung Ho Jang, Jun Chan Song, Hae Min Jo
Ann Rehabil Med 2013;37(2):235-240.   Published online April 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.2.235
Correction in: Ann Rehabil Med 2013;37(3):459
Objective

To describe a hand-stretching device that was developed for the management of hand spasticity in chronic hemiparetic stroke patients, and the effects of this device on hand spasticity.

Methods

Fifteen chronic hemiparetic stroke patients with finger flexor spasticity were recruited and randomly assigned to an intervention group (8 patients) or a control group (7 patients). The stretching device consists of a resting hand splint, a finger and thumb stretcher, and a frame. In use, the stretched state was maintained for 10 minutes per exercise session, and the exercise was performed twice daily for 4 weeks. Spasticity of finger flexor muscles in the two groups was assessed 3 times, 4 weeks apart, using the Modified Ashworth Scale (MAS). Patients in the intervention group were assessed twice (pre-1 and pre-2) before and once (post-1) after starting the stretching program.

Results

Mean MAS (mMAS) scores at initial evaluations were not significantly different at pre-1 in the intervention group and at 1st assessment in the control group (p>0.05). In addition, no significant differences were observed between mMAS scores at pre-1 and pre-2 in the intervention group (p>0.05). However, mMAS scores at post-1 were significantly lower than that at pre-2 in the intervention group (p<0.05). Within the control group, no significant changes in mMAS scores were observed between 1st, 2nd, and 3rd assessments (p>0.05). In addition, mMAS scores at post-1 in the intervention group were significantly decreased compared with those at the 3rd assessment in the control group (p<0.05).

Conclusion

The devised stretching device was found to relieve hand spasticity effectively in chronic hemiparetic stroke patients.

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Causes of Hand Tingling in Visual Display Terminal Workers
Sein Oh, Hyung Kuk Kim, Jehwan Kwak, Taikon Kim, Seong Ho Jang, Kyu Hoon Lee, Mi Jung Kim, Si-Bog Park, Seung Hoon Han
Ann Rehabil Med 2013;37(2):221-228.   Published online April 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.2.221
Objective

To offer the basic data about the causes and distribution of hand tingling, symptoms and physical findings, and pressure pain threshold in desk workers.

Methods

Five physiatrists participated in the screening test composed of history and physical examination. A total of 876 desk workers were evaluated and of them 37 subjects with hand tingling were selected. For further analyzing, detailed history taking and meticulous physical examination were taken. Pressure pain threshold (PPT) at the infraspinatus, upper trapezius, flexor carpi radialis, rhomboideus, and flexor pollicis longus were examined. PPT measurements were repeated three times with two minute intervals by a pressure algometer. Electrodiagnostic study was done to detect potential neurologic abnormalities.

Results

The causes of hand tingling in order of frequency were: myofascial pain syndrome, 68%; cervical radiculopathy, 27%; rotator cuff syndrome, 11%; tenosynovitis, 8%; and carpal tunnel syndrome, 5%. The location of trigger points in the myofascial pain syndrome, which were proven to evoke a tingling sensation to the hand in order of frequency were: infraspinatus, 65.4%; upper trapezius, 57.7%; flexor carpi radialis, 38.5%; rhomboideus 15.4%; and flexor pollicis longus 11.5%. The PPT of the affected side was significantly lower than that of the unaffected side in myofascial pain syndrome (p<0.05).

Conclusion

The most common cause of hand tingling in desk workers was myofascial pain syndrome rather than carpal tunnel syndrome. Common trigger points to evoke hand tingling were in the infraspinatus and upper trapezius.

Citations

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    Faye Y. Chiou‐Tan
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    Chandler L. Bolles, Ahmad Abdella, Patrick J. Battaglia
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Case Reports

Alien Hand Syndrome in Stroke - Case Report & Neurophysiologic Study -
Yong Won Park, Chang Hwan Kim, Myeong Ok Kim, Hyung Joon Jeong, Han Young Jung
Ann Rehabil Med 2012;36(4):556-560.   Published online August 27, 2012
DOI: https://doi.org/10.5535/arm.2012.36.4.556

Alien Hand Syndrome is defined as unwilled, uncontrollable, but seemingly purposeful movements of an upper limb. Two major criteria for the diagnosis are complaint of a foreign limb and complex, autonomous, involuntary motor activity that is not part of an identifiable movement disorder. After a cerebrovascular accident in the corpus callosum, the parietal, or frontal regions, various abnormal involuntary motor behaviors may follow. Although different subtypes of Alien Hand Syndrome have been distinguished, this classification clearly does not cover the wide clinical variety of abnormal motor behaviors of the upper extremity. And there are few known studies about the neurophysiology of this syndrome using transcranial magnetic stimulation (TMS). We recently experienced 2 rare cases of Alien Hand Syndrome which occurred after anterior cerebral artery (ACA) infarction. A 72 year-old male with right hemiplegia following a left ACA infarct had difficulty with voluntarily releasing an object from his grasp. A 47 year-old female with left hemiplegia following a right ACA infarct had a problem termed 'intermanual conflict' in which the two hands appear to be directed at opposing purposes. Both of them had neurophysiologic studies done, and showed reduced amplitude by single pulse MEP and a lack of intracortical inhibition (ICI) by paired pulse TMS. No abnormalities were found in SSEP.

Citations

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  • Alien hand syndrome as the initial presentation of posterior cerebral artery infarction: a case report
    Fatima Alabandi, Zahra Gaw
    BMC Neurology.2026;[Epub]     CrossRef
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    Gaia Galluzzi, Fabiana Mogavero, Maddalena Boccia, Gabriella Bottini, Maria Paola Ciurli, Rita Formisano, Chiara Incoccia, Maria Bianca Muneghina, Alice Teghil, Antonella Di Vita
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    Valentina Pacella, Sara Bertagnoli, Riccardo Danese, Cristina Bulgarelli, Valeria Gobbetto, Giuseppe Kenneth Ricciardi, Valentina Moro
    Cortex.2025; 182: 181.     CrossRef
  • Post‑stroke disorders of ownership and agency, alien/anarchic hand syndrome: A longitudinal case analysis and systematic review
    Davide Cardile, Serena Campana, Carmelo Mario Vicario, Fabrizio Doricchi, Stefano Lasaponara, Rocco Salvatore Calabrò, Francesco Tomaiuolo
    The Clinical Neuropsychologist.2025; : 1.     CrossRef
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    Khaled Moghib, Trisha Shivashankar, Thoria I. Essa Ghanm, Mona I. Elshamy, Eman G. Allam, Salomon Izere, Md. Al Hasan Mia, Muhannad Wael Abu Arafeh, Mostafa Meshref
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    Ghada Rashwan, Sara Elagha, Tahani Aldaham, Liza Thomas
    Cureus.2024;[Epub]     CrossRef
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    Dylan Ryan, Tasnim Mushannen, Scott Le
    The Neurohospitalist.2024; 14(3): 308.     CrossRef
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    Kendall Higgins, Stephanie Gandelman, Julien Menko
    The American Journal of Emergency Medicine.2024; 82: 214.e1.     CrossRef
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    Takumi Matsuyama, Koji Hayashi, Mamiko Sato, Asuka Suzuki, Yuka Nakaya, Toyoaki Miura, Yasutaka Kobayashi
    Cureus.2024;[Epub]     CrossRef
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    Jei Hak Myung, Sung-Bom Pyun
    Dysphagia.2023; 38(1): 227.     CrossRef
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    Yiming Ma, Ye Liu, Xuejing Yan, Yi Ouyang
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    Hsin‐Chen Liu, Austin Apramian, Antonio Liu
    Clinical Case Reports.2020; 8(11): 2204.     CrossRef
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    S. Rosie Gellman, Yu-Tze Ng
    Pediatric Neurology.2018; 89: 66.     CrossRef
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    Xiaoyu Gao, Bing Li, Wenzheng Chu, Xuwen Sun, Chunjuan Sun
    Experimental and Therapeutic Medicine.2016; 12(4): 2129.     CrossRef
  • Paroxysmal posterior variant alien hand syndrome associated with parietal lobe infarction: case presentation
    Bekir Enes Demiryürek, Aslı Aksoy Gündogdu, Bilgehan Atılgan Acar, Aybala Neslihan Alagoz
    Cognitive Neurodynamics.2016; 10(5): 453.     CrossRef
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    Ihtesham Aatif Qureshi, Daniel Korya, Darine Kassar, Mohammed Moussavi
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    Florian Brugger, Marian Galovic, Bruno J. Weder, Georg Kägi
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    Ragesh Panikkath, Deepa Panikkath, Deb Mojumder, Kenneth Nugent
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    Takatoshi HARA, Kiyohito KAKITA, Mami KODAMA, Takaaki DOI, Masahiro ABO
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  • 19 Crossref
Augmentative and Alternative Communication Training Using Eye Blink Switch for Locked-in Syndrome Patient
Si-Woon Park, You-lim Yim, Sook-hee Yi, Hyun-young Kim, Seung-min Jung
Ann Rehabil Med 2012;36(2):268-272.   Published online April 30, 2012
DOI: https://doi.org/10.5535/arm.2012.36.2.268

Locked-in Syndrome is a severe pontine stroke causing quadriplegia, lower cranial nerve paralysis, and mutism with preservation of only vertical gaze and upper eyelid movement in a conscious patient. We present a case of a Locked-in Syndrome patient who received communication training with augmentative and alternative communication equipment by using eye blinks. After 3 weeks of training, the patient was able to make an attempt to interact with other people, and associate a new word by Korean alphabet selection. Augmentative and alternative communication equipment which uses eye blinks might be considered to be beneficial in improving the communication skills of locked-in syndrome patients.

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    Markus Schmidt, Tobias Tempel
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    Marco Caligari, Marica Giardini, Marco Guenzi
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    Alberto J. Molina-Cantero, Clara Lebrato-Vazquez, Manuel Merino-Monge, Roylan Quesada-Tabares, Juan A. Castro-Garcia, Isabel M. Gomez-Gonzalez
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  • Beyond the gaze: Communicating in chronic locked-in syndrome
    Zulay R. Lugo, Marie-Aurélie Bruno, Olivia Gosseries, Athena Demertzi, Lizette Heine, Marie Thonnard, Véronique Blandin, Frédéric Pellas, Steven Laureys
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  • A concept-environment for computer-based augmentative and alternative communication founded on a systematic review
    Luiz Fernando Batista Loja, Renato de Sousa Gomide, Fabiana Freitas Mendes, Ricardo Antonio Gonçalves Teixeira, Rodrigo Pinto Lemos, Edna Lúcia Flôres
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Original Articles

Effect of Stimulation Polarity of Transcranial Direct Current Stimulation on Non-dominant Hand Function
Min Kyun Sohn, Bong Ok Kim, Hyun Tak Song
Ann Rehabil Med 2012;36(1):1-7.   Published online February 29, 2012
DOI: https://doi.org/10.5535/arm.2012.36.1.1
Objective

To evaluate motor excitability and hand function on the non-dominant side according to the polarity of transcranial direct current stimulation (tDCS) on the motor cortex in a healthy person.

Method

tDCS was applied to the hand motor cortex for 15 minutes at an intensity of 1 mA in 28 healthy right-handed adults. Subjects were divided randomly into four groups: an anodal tDCS of the non-dominant hemisphere group, a cathodal tDCS of the non-dominant hemisphere group, an anodal tDCS of the dominant hemisphere group, and a sham group. We measured the motor evoked potential (MEP) in the abductor pollicis brevis and Jabsen-Taylor hand function test (JTT) in the non-dominant hand prior to and following tDCS. All study procedures were done under double-blind design.

Results

There was a significant increase in the MEP amplitude and a significant improvement in the JTT in the non-dominant hand following anodal tDCS of the non-dominant hemisphere (p<0.05). But there was no change in JTT and a significant decrease in the MEP amplitude in the non-dominant hand following cathodal tDCS on the non-dominant hemisphere and anodal tDCS of the dominant hemisphere.

Conclusion

Non-dominant hand function is improved by increased excitability of the motor cortex. Although motor cortex excitability is decreased in a healthy person, non-dominant hand function is maintained. A homeostatic mechanism in the brain might therefore be involved in preserving this function. Further studies are warranted to examine brain functions to clarify this mechanism.

Citations

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  • The Influence of Transcranial Alternating Current Stimulation on the Excitability of the Unstimulated Contralateral Primary Motor Cortex
    Erik W. Wilkins, Richard J. Young, Ryder Davidson, Reese Krider, George Alhwayek, Jonathan A. Park, Armaan C. Parikh, Zachary A. Riley, Brach Poston
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    Liam C. Tapsell, Matheus D. Pinto, Ann-Maree Vallence, Casey Whife, Maria Luciana Perez Armendariz, Shaswat Senger, Jack Andringa-Bate, Dana Hince, Myles C. Murphy
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    Erik W. Wilkins, Richard J. Young, Daniel Houston, Eric Kawana, Edgar Lopez Mora, Meghana S. Sunkara, Zachary A. Riley, Brach Poston
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    Jitka Veldema, Dennis Alexander Nowak, Kathrin Bösl, Alireza Gharabaghi
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    Elisabeth Kaminski, Tom Maudrich, Pauline Bassler, Madeleine Ordnung, Arno Villringer, Patrick Ragert
    Frontiers in Aging Neuroscience.2022;[Epub]     CrossRef
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    Adrianna Giuffre, Ephrem Zewdie, James G. Wrightson, Lauran Cole, Helen L. Carlson, Hsing-Ching Kuo, Ali Babwani, Adam Kirton
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    Mujda Nooristani, Thomas Augereau, Karina Moïn-Darbari, Benoit-Antoine Bacon, François Champoux
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    Jared Cooney Horvath, Olivia Carter, Jason D. Forte
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    Bernadette T. Gillick, Adam Kirton, Jason B. Carmel, Preet Minhas, Marom Bikson
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Effects of Modified Dynamic Metacarpophalangeal Joint Flexion Orthoses after Hand Burn
Ji Soo Choi, Jeong Hyeon Mun, Ju Youn Lee, Jong Hyun Jeon, Yun Jae Jung, Cheong Hoon Seo, Ki Un Jang
Ann Rehabil Med 2011;35(6):880-886.   Published online December 30, 2011
DOI: https://doi.org/10.5535/arm.2011.35.6.880
Objective

To assess the effectiveness of modified dynamic metacarpophalangeal joint flexion orthoses for treatment of post-burn hand contractures.

Method

We enrolled 42 hand burn patients with limited range of motion at the metacarpophalangeal joints in this study. The patients were randomly assigned into either a control or an orthotic group. Both groups received the standard rehabilitation therapy focused on hand therapy; 21 subjects in the orthotic group wore a splint for 3 hours per day for 8 weeks. Hand function was measured by active range of motion, grip strength and other assessment tools. All parameters were estimated using the Mann-Whitney U test at the beginning and the end of the treatment after 8 weeks.

Results

The 21 subjects that had an orthotic intervention showed significant improvement in the range of motion at 2nd, 3rd, 4th and 5th metacarpophalangeal joints (p<0.05). However, the grip strength was not significantly increased after the 8 weeks of treatment compared to control group (p>0.05). There was a significant difference in the hand function scales between the 2 groups (p<0.05).

Conclusion

The modified dynamic metacarpophalangeal joint flexion orthoses provide continuous flexion to metacarpophalangeal joint that is needed for the restoration of range of motion in post-burn hand contractures. For the clinical application of hand orthoses in patients with hand disorders, additional research into its affects are required.

Citations

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    Prosthetics & Orthotics International.2016; 40(1): 142.     CrossRef
  • Clinical response of dynamic splint using functional scales for the extension contracture of the metacarpophalangeal joint
    Jun Nakayama, Mituru Horiki, Kakuro Denno, Kazunori Ogawa, Hisao Oka, Kazuhisa Domen
    Asian Journal of Occupational Therapy.2016; 12(1): 85.     CrossRef
  • Effects of a Modified Hand Compression Bandage for Treatment of Post-Burn Hand Edemas
    Won Yong Park, Soo Jin Jung, So Young Joo, Ki Un Jang, Cheong Hoon Seo, Ah Young Jun
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  • Development of a Dynamic Traction and Flexion Splint for MP joint Extension Contractures
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    Biomechanisms.2014; 22: 249.     CrossRef
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Correlation of the Motor Evoked Potentials Amplitude and Hand Function of the Affected Side in Stroke.
Son, Soo Youn , Park, Sung Hee , Seo, Jeong Hwan , Ko, Myoung Hwan
J Korean Acad Rehabil Med 2011;35(1):34-41.
Objective
To investigate the correlation between the motor evoked potentials (MEPs) amplitude of 1st dorsal interosseus in affected limbs and affected hand function after stroke. MethodWe enrolled 109 patients with acute and subacute 1st attack stroke. Transcranial magnetic stimulation (TMS) was applied to the motor cortex and MEP was recorded at the 1st dorsal interossei (DI) muscle. MEP parameters were latency of the affected side, latency ratio (latency of affected side/latency of unaffected side), amplitude of affected side and amplitude ratio (amplitude of affected side/latency of unaffected side). Hand function tests (HFT) including hand power measures and a nine hole peg test (NHPT) were conducted and the ratios of the value of the affected hand to unaffected hand were used for the analysis. The Korean version of the modified Barthel index (K-MBI) and the manual muscle test (MMT) of finger flexion were also evaluated. Correlation between MEP parameters and the clinical variables such as HFT, K-MBI and MMT grades were analyzed. ResultsWhile MEPs in the affected 1st DI were recorded in fifty six patients, MEPs were not recorded in forty nine patients. The responsiveness of MEPs was significantly correlated with the HFT, K-MBI and MMT grades. The amplitude ratio had the most significant correlation with the HFT and MMT grade in this MEP study. Also, the amplitude ratio had more significant correlations with the K-MBI score compared with other MEP parameters. Conclusion We concluded that the amplitude ratio may be a useful MEPs parameter for indicating hand function.
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Improvement of Hand Function with Transcranial Direct Current Brain Polarization in Stroke Patients.
Ko, Myoung Hwan , Han, Sang Hyoung , Park, Sung Hee , Seo, Jeong Hwan
J Korean Acad Rehabil Med 2009;33(3):259-264.
Objective
To investigate therapeutic effects of anodal direct current (DC) polarization on the primary motor cortex in subacute and chronic stroke patients by measuring changes of hand function and corticospinal excitability before and after stimulation. Method: Fourteen subacute and chronic stroke patients were included in this study. This study was designed as a sham-controlled, double-blind, and crossover experiment. The anode was positioned on the primary motor cortex of the affected hemisphere. The primary motor cortex was identified using transcranial magnetic stimulation (TMS), the motor evoked potentials (MEPs) were recorded by surface electrodes placed over the contralateral first dorsal interosseous muscle. DC was delivered for 20 minute at 2 mA with 25 cm2 saline-soaked sponge electrodes. Before and after DC polarization, we checked the box and block test, nine hole peg test, grip power, lateral prehension power, MEPs amplitude, and MEPs latency. Results: The box and block test, grip power, lateral prehension power, and MEPs amplitude increased after anodal DC to primary motor cortex (p<0.05). Positive correlation showed between improvement of box and block test and change of MEPs amplitude (r=0.808, p=0.001). Conclusion: Increased hand functions and the corticospinal tract excitability were obtained by 2 mA, 20 minute anodal DC polarization. Anodal DC polarization to primary motor cortex may play a potential role for facilitating the corticospinal tract thereby enhancing hand motor recovery in stroke patients. (J Korean Acad Rehab Med 2009; 33: 259-264)
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Severity of Disability and Quality of Life in Handicapped Persons in Welfare Facility and Home in Goyang City.
Kim, Seong Woo , Lee, Won Seok , Shin, Jung Bin , You, Sung , Lee, Sun Kyoung , Yun, Doo Sik , Choi, Young Sook
J Korean Acad Rehabil Med 2008;32(4):443-448.
Objective: To compare severity of disability and quality of life between the handicapped residing in a welfare facility and the handicapped living at home. Method: This research conducted a survey for the handicapped persons in Goyang city. The survey consisted of the following items: disability diagnosis, modified Barthel index (MBI), Korean-activities of daily living (K-ADL), 8-item short form health survey instrument (SF-8) and life domain satisfaction measure (LDSM). A total number of 144 handicapped persons participated, and 66 among them lived at home. Results: In regard to the range of activities of daily living MBI, K-ADL and quality of life; SF-8, those who resided in a welfare facility showed higher scores. In terms of satisfaction of life, the two groups did not show significant difference in housing, education and family relationship. However, as for leisure and health, those who resided in a welfare facility showed higher satisfaction. Conclusion: The handicapped persons residing in a welfare facility could function more independently in carrying out daily activities, and they showed higher quality and more satisfaction of life compared to those who lived at home. These results support that more attention would be needed for disabled persons at home to make welfare and rehabilitation policies. (J Korean Acad Rehab Med 2008; 32: 443-448)
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Case Report

Striatal Hand in Traumatic Brain Injury: A case report.
Do, Hyun Kyung , Kim, Dong Gun , Jung, Kyu Young , Kim, Hyun Dong
J Korean Acad Rehabil Med 2008;32(3):345-348.
Striatal hand is characterized by flexion in metacarpopharyngeal (MCP) joints and hyperextension in proximal interphalangial (PIP) joints and flexion in distal interphalangeal (DIP) joint. In clinical practice, this problem is often overlooked or misdiagnosed as rheumatoid arthritis and the opportunity for an early diagnosis and a correct management of the patient's is missed. In this report, a case with striatal hand following traumatic brain injury (TBI) without cardinal Parkinsonian signs is presented, and the differential diagnosis of the disease is discussed. A-62-year-old man presented with hemiplegia subsequent to traumatic brain injury. During the last two years, "swan neck" deformity of the hands occurred. We could diagnose this case as striatial hand with exclusion of similar rheumatologic causes by careful study and its characteristic deformity pattern. Clinician should consider the possibility of striatal hand when the patient with TBI presents swan neck deformity for an early diagnosis and a correct management. (J Korean Acad Rehab Med 2008; 32: 345-348)
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Original Articles

Hand Function and Diffusion Tensor Imaging according to Response of Evoked Potentials in Post-stroke Hemiplegic Patients.
Park, Gi Young , Cho, Jang Hyuk , Lee, So Young , Bae, Jung Ho , Sohn, Chul Ho , Sohn, Sung Il
J Korean Acad Rehabil Med 2008;32(2):182-188.
Objective: To investigate the association between evoked potentials and fractional anisotropy (FA) ratio in posterior limb of the internal capsule and hand movement scale (HMS) in post-stroke hemiplegic patients.

Method: Thirty-six post-stroke hemiplegic patients with a lesion in the internal capsule were included in this study. Diffusion tensor imaging (DTI) was performed with a 3.0 tesla MR at about 1 month after stroke. FA ratio was measured in posterior limb of the internal capsule of the patients. Motor evoked potential (MEP) was obtained by magnetic stimulation of the motor cortex and recorded from the abductor pollicis muscle. Somatosensory evoked potential (SSEP) was obtained by electrical stimulation of the median nerve at the wrist and recorded from the somatosensory cortex. Hand movement scale was obtained at about 1 month and 3 months after stroke.

Results: Hand movement scale at about 1 month and 3 months after stroke and FA ratio were reduced significantly in patients who showed no response on MEP. However, no significant differences were observed between the patients who showed SSEP response and those who did not. FA ratio and hand movement scale were highly correlated to each other.

Conclusion: MEP and FA ratio can be helpful in assessing the hand function at about 1 month and 3 months in post-stroke hemiplegic patients. (J Korean Acad Rehab Med 2008; 32: 182-188)

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New Scoring System for Jebsen Hand Function Test.
Kim, Jung Hwan , Kim, Il Soo , Han, Tai Ryoon
J Korean Acad Rehabil Med 2007;31(6):623-629.
Objective
To develop a new scoring system for Jebsen Hand Function Test (JHFT) and test validity of the new score scale in stroke patients. Method: JHFT and the modified Barthel index upper extremity subtest (MBI-U) were performed on a total of 210 stroke patients at a tertiary university hospital. Based on JHFT raw data, scores were calculated from the existing scoring system and the new one. Validity of scores from each system was evaluated by comparing each score with the MBI-U score. Floor effects of both scoring system were compared. Results: In all the seven subtest items of JHFT, the floor effect of the new scoring system was far lower than that of the existing one. Pearson correlation coefficient between the score from the new scoring system and the MBI-U score was 0.4880 (p<0.0001, n=210). Conclusion: 'New score scale' -a scoring system for JHFT based upon new criteria- was presented. New score scale for JHFT has reduced floor effect and is valid in stroke patients. (J Korean Acad Rehab Med 2007; 31: 623-629)
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Scar Quality and Hand Function after Moist Exposed Burn Ointment and Skin Graft Treatment in Full Thickness Hand Burn.
Shin, Ji Cheol , Seo, Cheong Hoon , Jang, Ki Un , Jung, Ki Yang
J Korean Acad Rehabil Med 2007;31(5):582-589.
Objective
To compare the scar formation and hand function between moist exposed burn ointment (MEBO) treatment and conventional skin graft in full thickness hand burns. Method: Prospective comparative study was done between MEBO treatment group and conventional skin graft group. Full thickness burn wound scars on dorsal hand were compared. Scars were assessed with the Vancouver scar scale and other objective measurement tools such as pigmentation, erythema, pliability, transepideramal water loss, thickness and perfusion. Hand function was evaluated by the Jebsen hand function test and Michigan Hand Function Questionnaire. Results: Vancouver Scar scale showed significantly better scores in the MEBO group than in the conventional skin graft group. Scar thickness and transepidermal water loss were greater in the MEBO treatment group whereas pigmentation value was greater in the conventional skin graft group. There was no significant difference in the hand function between the two groups. Conclusion: MEBO application could be an alternative treatment to conventional skin graft treatment in full thickness hand burn wounds. In the future, more studies are yet to come how MEBO treatment may affect the skin condition of the burn injuries. (J Korean Acad Rehab Med 2007; 31: 582-589)
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Improvement of Apraxia and Hand Function with Transcranial Direct Current Brain Polarization in Patients with Corticobasal Degeneration.
Ko, Myoung Hwan , Wassermann, Eric M , Seo, Jeong Hwan , Kim, Yun Hee
J Korean Acad Rehabil Med 2007;31(3):278-282.
Objective
To see whether anodal direct current (DC) polarization of the inferior parietal cortex (IPC) and the primary sensorimotor area (SM1) in corticobasal degeneration (CBD) patients leads to improvement of praxia and finger motion. Method: Twelve patients with CBD were enrolled. This single blind crossover study had three arms, anodal DC to IPC, anodal DC to SM1, and shame polarization on occipital area. DC was delivered for 40 minute at 2 mA with 25 cm2 sponge electrodes. Before and 20 min after the start of polarization, we performed the test of oral and limb apraxia (TOLA), finger tapping frequency, and grooved pegboard test. Results: The total score of TOLA was increased 5.4±2.3% after anodal DC to IPC. The scores of limb apraxia and picture gesture subtests of TOLA, not of oral apraxia subtest, increased significantly after anodal DC to IPC compared to sham DC polarization (p<0.05). In anodal DC to SM1 group, the finger tapping frequency increased 15.5±14.1%, which was significantly greater than in sham group (p<0.05). Conclusion: These results showed beneficial effects of anodal DC polarization on apraxia and hand function in CBD patients. In addition, these effects for apraxia and hand movement were dependent on their stimulation sites of brain. (J Korean Acad Rehab Med 2007; 31: 278-282)
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Follow Up of Asymptomatic Hands in the Patients with Unilateral Carpal Tunnel Syndrome.
Park, Won Beom , Lee, Seong Jae , Hyun, Jung Keun , Jeon, Jae Yong , Kim, Kyoung Yol
J Korean Acad Rehabil Med 2006;30(6):575-579.
Objective
To know whether nerve conduction study (NCS) could predict later development of carpal tunnel syndrome (CTS) in asymptomatic hands of the patients with unilateral CTS. Method: Thirty four patients with unilateral CTS were studied. Subjects were divided into groups with or without the delay of latency, based on the results of initial NCS of asymptomatic hands. After follow up for more than 6 months clinically and electrodiagnostically, the development of CTS in initially asymptomatic hands was compared between groups. Results: At follow up, CTS was diagnosed in 83% of the subjects in the group with motor latency delay at first study, while it was diagnosed in 32% of the subjects in the group without motor latency delay. In the group with sensory latency delay at first study, CTS was diagnosed in 78% of subjects at follow up, whereas only 19% of the subjects developed CTS in the group without sensory latency delay. The incidence of CTS at follow up was significantly higher in the group with motor or sensory latency delay at first study. Conclusion: In unilateral CTS, latency delay in motor or sensory NCS of asymptomatic hands may suggest a greater risk of later development of CTS. (J Korean Acad Rehab Med 2006; 30: 575-579)
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Case Report

Problems of Driver's License Test for the Handicapped People with Weak Upper Extremities in Korea: A case report.
Lee, Ju Hyun , Lee, Bum Suk , Lim, Mun Hee
J Korean Acad Rehabil Med 2005;29(2):235-238.
The mobility provided by a car can obviously give much greater independence and opportunities for work and social activities to people with physical handicaps, even though they may still find it difficult to drive an ordinary production car. But, in our country, the driver's license test is to the disadvantage for driving of the handicapped people who can drive a car with suitable modifications. The authors examined the relationship between the motor ability test of driver's license test for the handicapped people and actual car-driving abilities in three handicapped people who have driven suitably modified cars for several years. All three subjects failed in steering wheel operation of motor ability test and one subject failed in parking brake operation. These results showed that the motor ability test of driver's license test for the handicapped people was inappropriate and had to be changed. (J Korean Acad Rehab Med 2005; 29: 235-238)
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Original Articles

Historically WHO has concentrated on infection control and mortality reduction. However, diagnosis alone does not explain what patients can do, what their prognosis will be. To answer these questions, significant challenges are presented in model the International Classification of Impairment, Disability and Handicap (ICIDH) announced in 1980. Following several revisions of ICIDH, WHO (2001) finally approved the International Classification of Functioning, Disability and Health (ICF), which is universal and clear terminology with qualifiable assessment measures. The ICF is a new form which (1) is not based on disability, rather on human function, (2) is interactive rather than linearly progressive, and (3) is not medical or social model, rather integration model. Also, the new language ICF is an landmark event for rehabilitation. Key to successful rehabilitation management is the understanding and proper assessment of the relationship between disease (ICD-10) and impaired body functions and structures and psychosocial and environmental factors(ICF). (J Korean Acad Rehab Med 2004; 28: 401-411)
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Changes in Ipsilateral Motor Cortex Excitability during Hand Exercise in Normal Subjects.
Yoo, Woo Kyoung , Jun, Ah Young , Jung, Kwang Ik , Park, Dong Sik , Ju, Young Su
J Korean Acad Rehabil Med 2004;28(2):146-150.
Objective
To observe the effect of complexity of unilateral hand activity or dominance of hand on ipsilateral motor cortex excitability.Method: Twenty healthy volunteers of right handedness were recruited. We applied the transcranial magnetic stimulation on right hemisphere, and measured motor evoked potential (MEP) at left first dorsal interossei (FDI). We observed the changes of MEP amplitude during the execution of three different complexities of right finger movement. We set the motor tasks as (1) relaxed state, (2) repetitive opposition of 3rd finger (simple exercise) and (3) opposition of 3rd, 5th, 2nd, 4th finger (complex exercise). These tasks were performed within one minute, and repeated 3 times. To observe the effect of hand dominance, we also measured MEP at right FDI during left hand movements.Results: Ipsilateral motor cortex was significantly facilitated by ipsilateral voluntary hand activity (p<0.01). And the MEP amplitude was also increased by complexity of hand exercise. Conclusion: We found that the excitability of ipsilateral motor cortex was changed by unilateral hand exercise, and the excitability was increased by complexity of hand exercise. (J Korean Acad Rehab Med 2004; 28: 146-150)
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The Chronological Review of Uninvolved Hand Function in Stroke Patients.
Han, Tai Ryoon , Yoon, Kyung Jae , Jung, Se Hee
J Korean Acad Rehabil Med 2004;28(1):13-19.
Objective
To investigate chronological change of uninvolved hand function in hemiplegic patients and to assess any correlation between the improvement in Jebsen hand function test (JHFT) and modified Barthel index (MBI) and between the improvement in hand power and modified Barthel index. Method: JHFT, MBI and hand power measurement were done twice on twenty hemiplegic patients. Initial test were done after 36.5⁑18.2 days from onset and follow-up interval were 28.2⁑7.2 days. Results: We could find statistically significant time shortening in JHFT (p<0.01) and power increment (p<0.05) of uninvolved hands. None of MBI was normalized except for feeding. Majority were not normalized in JHFT. Patients who improved in stacking checkers in JHFT and in lateral pinch power showed improvement in total MBI score. But any correlation between the improvement in other items of JHFT and each items of MBI and between the improvement in hand power and each items of MBI were not found. Conclusion: Not normalized uninvolved hand function of the majority in the follow-up test proved the necessity of active rehabilitation on the uninvolved hand in acute stage. Generally there was no correlation between the improvement in JHFT and MBI, and between the improvement in HP and MBI. (J Korean Acad Rehab Med 2004; 28: 13-19)
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Effect of Constraint-Induced Movement Therapy in Chronic Hemiplegic Patients.
Kim, Deog Young , Park, Chang Il , Chang, Won Hyuk , Jang, Yong Won
J Korean Acad Rehabil Med 2003;27(6):813-818.
Objective: To evaluate the effectiveness of constraint-induced movement therapy (CIT) for chronic hemiplegic patients and to investigate the factors that influence on the effectiveness of CIT.

Method: Forty two chronic stroke patients were enrolled and classified into two groups, experimental and control group. The experimental group took CIT for 2 weeks. CIT consisted of restraint of the unaffected upper extremity with massive training of the affected upper extremity. The motor function of patient's upper extremity was assessed by Manual Function Test (MFT) and Jebsen Hand Function Test before treatment, at 2 weeks and at 8 weeks after the treatment.

Results: The withdrawal rate was 46.7% during CIT period. There was substantial significant improvements in MFT and Jebsen Hand Function Test after 2 weeks of treatment in the experimental group (p<0.05). The effects in the experimental group were maintained at 6 weeks after cessation of the treatment.

Conclusion: CIT is considered to be an effective treatment for motor function of the chronic hemiplegic upper extremity motor function, and will be useful as an additional therapeutic tool. (J Korean Acad Rehab Med 2003; 27: 813-818)

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Isokinetic Evaluation of Shoulder Joint Strength in College Handball Players and General College Students.
Kim, Kweon Young , Shin, Su Beom , Song, Ji Won
J Korean Acad Rehabil Med 2003;27(5):774-777.
OBJECTIVE
To obtain the comparison data of the shoulder strength between handball players of college and general college students. METHOD: Fifteen subjects from each group, college handball players and general college students groups were tested. Peak torque, peak torque ratio of internal rotator to external rotator, peak torque to body weight ratio and average work during isokinetic exercise were studied. RESULTS: All of the parameters tested in handball players of college were greater than those of general college students. The peak torque in handball players was greater than that of general college students at 60o/sec, 180o/sec, which was statistically significant (p<0.05). The peak torque ratio of internal rotator to external rotator in dominant side of handball players was greater than the college group (p<0.05). The peak torque to body weight ratio at 60o/sec did not show significant differences between handball players of college and general college students. The average power at 60o/sec did not show significant differences between the two groups. CONCLUSION: The values of peak torque ratio of internal rotator to external rotator of the shoulder joint in dominant side of handball players were greater than those of the general college students. So it was suggested this result have to be considered in selecting handball players and exercise prescription.
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Recovery of Hand Motor Function in Patients with Subcortical Hemorrhage.
Yoo, Woo Kyoung , So, Eun Ha , Yun, Suk Bong , Jung, Seung Suk
J Korean Acad Rehabil Med 2002;26(6):672-680.
Objective
The aim of this study was to find out the factors related to the recovery of hand motor function in patients with subcortical hemorrhage. Method: We investigated 21 patients with subcortical hemorrhage prospectively. We used their CT and/or MR imaging for the localization and estimation of the size of lesion. The Hand Movement Scale (HMS) was used for evaluation of the hand function. Proprioception, initial shoulder and hand recovery were also measured every month for at least 6 months during the follow up periods. Results: There are 13 patients with putaminal hemorrhage and 8 patients with thalamic hemorrhage. There is no difference in general characteristics between the two groups. When recovery began within 4 weeks after onset, only thalamic hemorrhage patients showed significantly good recovery. Initial shoulder shrug, especially within 4 weeks after onset, could be one of the prognostic factors of good hand motor recovery. Putaminal hemorrhage patients, who had higher scores on the hand movement scale, showed early recovery of proprioceptive function. Conclusion: Among many other factors which can be involved in the recovery of hand function in patients with subcortical hemorrhage, the time of initial hand motor recovery, the time of initial shoulder shrug, and proprioceptive function were most important. (J Korean Acad Rehab Med 2002; 26: 672-680
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Quality of Life and Life Satisfaction of the Registered Disabled Persons in Uiwang City.
Rah, Ueon Woo , Kim, Kyong Mi , Lee, Il Yung , Shim, Dae Seop , Rhie, Kyong Seok , Im, In Dong , Ko, Yung Deug
J Korean Acad Rehabil Med 2002;26(5):615-625.

Objective: The purposes of this study were to investigate the factors influencing life satisfaction and quality of life (QOL) of the disabled persons and to help the planning and evaluation of Community Based Rehabilitation (CBR).

Method: Data were collected through personal interviews of 503 registrated disabled persons in Uiwang City. Demographic variables and scores of modified Barthel index (MBI), modified Lambeth disability screening questionnaire (MLDSQ), Craig handicap assessment and reporting technique (CHART) and life domain satisfaction measure (LDSM) were obtained.

Results: The score of LDSM was 4.0⁑1.0. Life satisfaction was related to the age, sex, employment status, severity of disability, educational level, housing and residence, level of instrumental activities of daily living and social integration. MLDSQ score was the most strong predictor of life satisfaction (p=0.00) followed by social integration (p=0.001) and total CHART scores (p=0.017). And the factors influencing the handicap were monthly income, severity of disability, employment, level of education and age.

Conclusion: Based on our study, we suggest that the CBR program of Uiwang City need to focus on improving functional ability and social skill of disabled individual and housing, and also promoting their vocational and educational status. (J Korean Acad Rehab Med 2002; 26: 615-625)

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Measurement of the Hand Control Operating Force in Cervical Cord Injured Drivers.
Kim, Ji Young , Lee, Bum Suk , Shin, Oh Soo , Cho, Hyun Woo , Kim, Byung Sik
J Korean Acad Rehabil Med 2002;26(1):32-36.

Objectives: To provide proper standards of handicapped driver's ability test in Korea and evolve new driving aids.

Method: Thirty-six cervical cord injured persons (C5∼C7) were evaluated with Baltimore Therapeutic Equipment work simulator to which a straight handle was attached. The isotonic torque on a straight handle was measured during forward and backward movement and isometric torque was measured at neutral position. Analysis of variance (ANOVA) was used to compare torque among three groups (C5∼C7).

Results: The forward and backward torque of C7 tetraplegics was significantly higher than that of C6 tetraplegics

(p<0.05). All of 12 persons with C5 tetraplegia could not pass the test. Only 1 out of 12 persons with C6 tetraplegia and all of 12 persons with C7 tetraplegia could pass the test. But 9 out of 12 persons with C5 tetraplegia and all of 12 persons with C6 tetraplegia could operate brake and accelerator with servo-hand control.

Conclusion: All of the C5 tetraplegics and 92% of the C6 tetraplegics could not pass the handicapped driver's ability test of Korea. Therefore it is necessary to evolve driving aids for the C5 and C6 tetrapleigics and to modify this test. (J Korean Acad Rehab Med 2002; 26: 32-36)

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The Proximal and Distal Interphalangeal Flexion Dysfunction, Opposition Palm Ratio and Thumb Index Ratio in the Korean Adults.
Jang, Ki Un , Jang, Yeong Uck , Yoo, Hyun Jae , Jeong, Kwang Ik , Kim, Do Hoon , Park, Dong Sik
J Korean Acad Rehabil Med 2001;25(6):1023-1030.

Objective: The purpose of this study was to evaluate the incidence of inability to flex proximal interphalangeal (PIP) and distal interphalangeal (DIP) joint in normal Koreans. The opposition palm ratio and thumb index ratio was also of interest.

Method: Randomly selected eighty nine normal Korean adults of 48 men and 41 women, with ages 20 to 79 years. The finger flexion was measured using the standard flexor digitorum superficialis (FDS) and flexor digitorum profundus (FDP) screening tests. Thumb index ratio and opposition palm ratio was also assessed additionally.

Results: In the sample population, 2 subjects (2.2%) were unable to bilaterally flex their fifth PIP joints independently. Four subjects (4.4%) were unable to flex one or both of their fourth or fifth DIP joints. These results show far less incidence of FDS dysfunction comparing with 52% of FDS dysfunction rate in Americans. The opposition palm ratio in men were 63.6% and in women 69.9%, indicating lower ratio in men. The thumb index ratio was not different statistically between the men and women.

Conclusion: These data suggest that the different incidences of FDS and FDP dysfunction should be considered in interpretation. The opposition palm ratio and thumb index ratio might be useful in the hand rehabilitation.

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The Static Rotation Force of Wheel by the Wheel Angle and Hand Position.
Sohn, Min Kyun , Yoon, Yong Soon , Kwon, Hyeok Su , Song, Jung Young
J Korean Acad Rehabil Med 2001;25(5):877-882.

Objective: The purpose of this study is to determine the proper hand position during driving by measuring of the wheel rotation strength according to the wheel angle and hand position to the wheel.

Method: BTE Work Simulator was used to measure the clockwise and counter clockwise static wheel rotation force of twenty healthy men in three different hand position (2∼10 spot, 3∼9 spot, and 4∼8 spot) and two different wheel angle (45o and 60o, average and peak force were measured during maximal isometric contraction.

Results: The average and peak force was significantly different by the wheel angle, and hand position (p<0.01), but the direction of rotation didn't an effect on the rotation force. The hand position was the most significant factor, especially wheel rotation force at 2∼10 spot hand position was significantly lower than that of 3∼9 spot and 4∼8 spot (p<0.05). The rotation force by the wheel angle was influenced by hand position, and lower in 60o wheel angle in the 2∼10 spot (p<0.05).

Conclusion: The rotation force of wheel was influenced by the hand position. Therefore proper hand position is recommended during driving to reduce muscle fatigue.

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Recovery from Motor Weakness of Ipsilateral Upper Limb Following Stroke Comparison on Recovery of Proximal Portion with That of Distal Portion.
Jung, Han Young , Yoon, Joon Shik , Kim, Sung A , Park, Bong Soon
J Korean Acad Rehabil Med 2001;25(5):745-750.

Objective: To observe the ipsilateral upper limb function after stroke comparing proximal with distal part and to determine how they recover after stroke.

Method: Cohort study of 72 patients with stroke in the middle cerebral arterial territory undergoing multidisciplinary stroke rehabilitation program. The main outcome was assessed by the Manual Function Test (MFT) for upper limb function, weekly.

Results: The recovery time of the ipsilateral upper limb to maximum function was 32.4 ⁑ 15.4 days. The functions of the ipsilateral shoulder and hand after stroke decreased significantly. Even at the maximum recovery, complete recovery was not seen. For ipsilateral shoulder, more severe functional deficits were seen with subcortical lesion than with cortical lesion, whereas for ipsilateral hands, no difference was seen between them.

Conclusion: Therefore, the fact that recoveries of the shoulders and hands were different according to the presence of cerebral cortical or subcortical lesions suggests that the brain structures that control these areas or the recovery mechanisms might be different.

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The Effects of Botulinum Toxin A on Upper Limb Function in Children with Cerebral Palsy.
Kim, Hyeon Sook , Hwang, Ji Hye , Lee, Peter KW , Jung, Sung Hyun , Park, Heui Dong , Cho, Eun Hee , Shim, Jong Sup , Kim, Jong Moon
J Korean Acad Rehabil Med 2001;25(4):594-600.

Objective: To evaluate the efficacy of botulinum toxin type A in the treatment of spasticitc and dystonic upper limbs in a group of cerebral palsy children

Method: Eighteen children with cerebral palsy who did not have fixed contractures in the wrist and hand were enrolled (mean age 9.0 years; range 6∼15). Measurements were obtained before and at 1 and 3 months after botulinum toxin A injections. Assessments included spasticity (modified Ashworth scale), range of motion of thumb and functional assessments including Melbourne assessment of unilateral upper limb function and Jebsen Taylor hand function test. Hand and forearm muscles were injected with 1∼3 u/kg botulinum toxin.

Results: Spasticity measured by modified Ashworth scale decreased by 1 month and diminished spasticity continued for 3 months. Range of motion of thumb increased by 1 and 3 months. In Jebsen hand function test, patients showed functional improvements in item 6 (lifting light weight object) and item 7 (lifting heavy object). Melbourne assessment of unilateral upper limb function scores improved from a mean value of 92 at baseline to a mean value of 101 at 1 month and a mean value of 105 at 3 months.

Conclusion: Botulinum toxin A would be helpful in some selected cerebral palsy patients with upper limb dysfunction. But further research including randomized controlled study is needed on the use of botulinum toxin A to improve function.

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Measurement of the Steering Torque in Cervical Cord Injured Persons Using BTE Work Simulator.
Shin, Oh Soo , Lee, Bum Suk , Kim, Kee Kyung , Na, In Soo , Kim, Byung Sik , Ahn, Sang Ho , Yum, Young Il
J Korean Acad Rehabil Med 2001;25(3):452-457.

Objective: To evaluate the standards of handicapped driver's ability test in Korea and available driving aids in cervical cord injured persons.

Method: Forty-two cervical cord injured persons (C5∼C8) were evaluated with BTE (Baltimore Therapeutic Equipment) work simulator. The isotonic turning torque was measured during clockwise and counter-clockwise turning. And isometric turning torque was measured at 12 directions.

Results: By the isotonic measurement, the turning torque increased in the lower level of injury. In the C6 tetraplegics, the counter-clockwise turning torque was significantly higher than clockwise. Among 25 persons with C5 or C6 tetraplegia, only 2 with C6 tetraplegia could operate the power steering with the lowest wheel turning torque (3.0 Nm). Only three persons (1 person with C7 tetraplegia, 2 persons with C8 tetraplegia) could pass the handicapped driver's ability test of Korea (9.4 Nm). By the isometric measurement, turning torque was lowest at left upper quadrant (10 to 12 o'clock direction) in clockwise rotation.

Conclusion: Among the 42 cervical cord injured persons, only 3 persons with C7 and C8 tetraplegia could pass the handicapped driver's ability test of Korea. And among 25 C5 and C6 tetraplegia, only 2 persons with C6 tetraplegia could operate the power steering. It seems to be essential to modify the standards of handicapped drivers ability test and to evolve the driving aids for the C5 and C6 tetraplegics in Korea.

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A Study on Driver Training Program for the Handicapped at the National Rehabilitation Center.
Shin, Oh Soo , Jang, Soon Ja , Kim, Uan Ho , Lee, Bum Suk , Hong, Byung Jin , Kim, Jae Hyung , Kim, Byung Sik
J Korean Acad Rehabil Med 2000;24(4):618-623.

Objective: To evaluate the results of driver training program for the handicapped.

Method: Retrospective study on the 699 disabled who participated in the two-months driver training program at the NRC (National Rehabilitation Center) from January 1995 to May 1998.

Results: 1) Of these subjects, 70.4% were men and 29.6% were women. 2) According to the disability grading system by the Ministry of Health and Social Welfare of Korea, 19.2% of the subjects had the first grade disability, 28.2% the second grade, 26.3% the third grade, 18.3% the fourth grade, 6.3% the fifth grade, and 1.4% the sixth grade. 3) The licensing rate was 74.6% for the first grade, 64.7% for the second grade, 70.9% for the third grade, 73.6% for the fourth grade, 55.8% for the fifth grade, and 70% for the sixth grade. 4) The licensing rate was the highest in the subjects with spinal cord injury (79.2%) and the lowest in the subjects with stroke (45.0%). 5) Overall, 78.2% of subjects licensed with automatic transmission and 21.8% with hand- control. On the other hand, in the subjects with spinal cord injury, 42.5% licensed with automatic transmission and 57.5% with hand-control.

Conclusion: The mean licensing rate of this program was 69.2%. Further study is required for the effect of cognitive function on driving test and various driving aids to promote the licensing rate for the handicapped.

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Evaluation of the Knee Extension Force in Korean Adults Using a Manual Muscle Tester.
Lee, Kyoung Moo , Kang, Jeon Wan
J Korean Acad Rehabil Med 2000;24(2):281-286.

Objective: The purpose of this study was to determine the knee extension force of healthy Korean adults by using a hand-held dynamometer and evaulate the relationship of knee extension force between each decade.

Method: One hundred and twenty healthy subjects (60 males, 60 females) between the ages of 20 and 79 years were tested for knee extension force by using Nicholas Manual Muscle Tester (MMT). Data were analyzed for means, standard deviations, test-retest reliability and correlation with variables by using the SPSS software package.

Results: The mean value of the knee extension force was 25.9⁑5.8 kg in the males and 16.5⁑4.1 kg in the females. Significant difference between each decade was found in the males but not in the females. The knee extension force of the males was stastically correlated with all of variables, i.e., age, weight and height, but the knee extension force of the females, was correlated only with weight. Intratester correlation coefficients were high for the Nicholas MMT to measure the knee extension force for healthy adults. Also the difference between the dominant and nondominant side for the knee extensor force was not significant, stastically.

Conclusion: This MMT may be useful to quickly and objectively evaluate force in the clinical setting.

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A Survey on Spinal Cord Injury Persons in Suwon City.
Rah, Ueon Woo , Lee, Il Yung , Moon, Hae Won , Lim, Min Jeong
J Korean Acad Rehabil Med 2000;24(1):42-51.

Objective: To collect the informations of the traumatic spinal cord injury persons in Suwon city.

Method: Seventy-five traumatic spinal cord injury persons were evaluated by the neurological level, American Spinal Injury Association scale, Functional Independence Measure (FIM), Craig Handicap Assessment and Reporting Technique (CHART), Beck Depression Inventory (BDI), and questionnaire on their voiding methods, complications, etc.

Results: The leading cause of 75 persons with traumatic spinal cord injury was a traffic accident. Among them, paraplegics were 46 persons. The most common complication was a pressure sore which was also the leading cause of their rehospitalization. Twenty-six persons voided by reflex. Among five dimensions of CHART, the physical independence score was the highest and the economic self sufficiency score was the lowest. The total CHART scores were significantly correlated with BDI scores, FIM scores, and level of injury.

Conclusion: This study revealed that physical impairment, disability and depression affect the handicaps of spinal cord injury persons. These data could be used to develop a social rehabilitation program for the spinal cord injury persons in the community.

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Effects of Unilateral Brain Damage on Ipsilateral Upper Extremity Function in Hemiplegia.
Kim, Hye Won , Ko, Young Jin , Kang, Sae Yun , Suh, Sun Sook
J Korean Acad Rehabil Med 2000;24(1):8-13.

Objective: The objective of this study is to determine the effect of unilateral brain lesion on hand strength and dexterity of ipsilateral side in hemiplegic patients and the change of strength and dexterity of ipsilateral hand after rehabilitation according to the side of brain lesion.

Method: Sixty four hemiplegic patients with unilateral brain lesion underwent hand function tests for the ipsilateral hand to the brain lesion. Grip strength, tip pinch, lateral pinch, and palmar pinch strength were measured, and Purdue pegboard test was performed. Results were compared with a group of forty age-matched healthy volunteers.

Results: There was significant decrement of hand strength and dexterity of ipsilateral side except grip strength in patients with unilateral brain lesion in the begining of rehabilitation compared with the controls. Hand strength and dexterity of ipsilateral hand was significantly improved after rehabilitation. There was no significant difference in hand strength and dexterity of ipsilateral side according to the side of hemispheric lesion.

Conclusion: Ipsilateral upper extremity function in hemiplegic patients may also be affected adversely, and therefore rehabilitation treatment for ipsilateral upper extremity function should be involved.

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Case Report
Paralytic Disease Related to Enterovirus 71 Infection: A report of 4 cases.
Wee, Jeong Sun , Lee, Sam Kyu , Seon, Kwang Jin
J Korean Acad Rehabil Med 1999;23(5):1046-1051.

Enterovirus 71 (E-71) infection was first described in 1974 after isolation studies of specimens from a series of patients who had severe neurological disease. One important feature of E-71 is its ability to cause paralytic disease. In the summer of 1997, we identified 4 children with E-71 infection. The striking feature of this outbreak is the occurrence of all cases with polio-like paralytic disease. Other disease associated with E-71 infection included aseptic meningitis, meningoencephalitis, respiratory disease, gastroenteritis, and hand-foot-mouth disease. The spectrum of illness observed in our cases was compared to that seen in other outbreaks. It is suggested that the significance of E-71 infection lies in its neuropathogenic potential. There is no specific, therapeutic modality of E-71 infection but its prognosis is good except some cases.

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