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"Chronic pain"

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Pain & Musculoskeletal rehabilitation

Chronic Neck Pain Prevalence Before and After COVID-19 Restrictions and Its Relationship With Digital Device Screen Viewing: A Population Study
Tomas Nakazato, Pablo Quezada, César Gutiérrez, Franco Romaní
Ann Rehabil Med 2024;48(2):124-134.   Published online April 22, 2024
DOI: https://doi.org/10.5535/arm.230030
Objective
To estimate the prevalence of chronic neck pain (CNP) among the adult population in Peru during the post-coronavirus disease 2019 (COVID-19) restriction period compared with that during the pre-pandemic period and evaluate its association with prolonged digital devices connected to the internet (DDCI) screen viewing.
Methods
We conducted a cross-sectional study using a representative sample of adults living in Peru in November 2022. A structured survey was employed to identify CNP, and the exposure variable was set as the duration of DDCI screen viewing. The McNemar test was used to compare CNP prevalence pre- and post-COVID-19 restrictions, and ordinal logistic regression was used to evaluate its association with prolonged screen viewing.
Results
A total of 1,202 individuals participated, with 52.8% females and 79.9% residing in urban areas. Following the restrictions, the prevalence of CNP occurring daily or almost daily and at least once a week was 14.8% and 27.8%, respectively (95% confidence Interval [95% CI], 12.6–17.3 and 24.9–30.9), representing a significant increase (p<0.001) compared with pre-pandemic estimates. Notably, among those viewing DDCI screens for ≥8 hours, the odds ratio for CNP frequency escalation compared with those who did not or rarely view screens was 1.61 (95% CI, 1.04–2.50; p=0.033).
Conclusion
Approximately 4 of 10 adults in Peru experienced CNP following the lifting of COVID-19 social restrictions, more than double the pre-pandemic prevalence. Furthermore, prolonged viewing of DDCI screens increased the risk of having this condition.
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Relief of Chronic Posterior Neck Pain Depending on the Type of Forest Therapy: Comparison of the Therapeutic Effect of Forest Bathing Alone Versus Forest Bathing With Exercise
Boram Kang, Taikon Kim, Mi Jung Kim, Kyu Hoon Lee, Seungyoung Choi, Dong Hun Lee, Hyo Ryoung Kim, Byol Jun, Seen Young Park, Sung Jae Lee, Si-Bog Park
Ann Rehabil Med 2015;39(6):957-963.   Published online December 29, 2015
DOI: https://doi.org/10.5535/arm.2015.39.6.957
Objective

To compare the pain-reducing effect of forest bathing alone versus forest bathing in combination with stretching and strengthening exercises in patients with chronic posterior neck pain.

Methods

Sixty-four subjects with posterior neck pain that had lasted more than 3 months were enrolled. They were randomly divided into a forest bathing alone (FBA) group and a forest bathing with exercise (FBE) group; each group included 32 subjects. All subjects from both groups walked every morning in the forest for about 2 hours for 5 days. In the afternoon, the FBE group did a stretching and strengthening exercise for about 4 hours; the FBA group had free time in the woods. Visual analog scale (VAS) on one day, VAS over the previous week, neck disability index (NDI), EuroQol 5D-3L VAS (EQ VAS) and index (EQ index), McGill pain questionnaire (MPQ), the number of trigger points in the posterior neck region (TRPs), and the range of motion of the cervical spine were evaluated on the first and last day of the program and compared between the two groups.

Results

The number of TRPs were significantly reduced in the FBE group compared with the FBA group (p=0.013). However, the other scales showed no significant difference between the two groups.

Conclusion

When patients with chronic posterior neck pain underwent a short-term forest bathing (less than 7 days) program, FBE was more effective in the reduction of the number of TRPs than FBA. However, all other pain measurement scales we evaluated showed no statistically significant difference between the two protocols.

Citations

Citations to this article as recorded by  
  • Waldtherapie zur Behandlung chronischer muskuloskelettaler Schmerzen
    Anika Schubert, Gabriele Röhrig-Herzog
    Zeitschrift für Phytotherapie.2025; 46(01): 11.     CrossRef
  • Effects of Nature-Based Multisensory Stimulation on Pain Mechanisms in Women with Fibromyalgia Syndrome: A Randomized Double-Blind Placebo-Controlled Trial
    Dogukan Baran Gungormus, Mónica Fernández-Martín, Miguel Enrique Ortigosa-Luque, José Manuel Pérez-Mármol
    Pain Management Nursing.2024; 25(1): 46.     CrossRef
  • Forest bathing: a quantitative exploration of emerging trends, patterns, and growth areas
    Alessandro Paletto, Sandra Notaro, Pavaleanu Cristian
    Journal of Forest Research.2024; 29(4): 239.     CrossRef
  • Forest Therapy Research in Europe: A Scoping Review of the Scientific Literature
    Elena Mazzoleni, Davide Donelli, Federica Zabini, Francesco Meneguzzo, Michele Antonelli
    Forests.2024; 15(5): 848.     CrossRef
  • Nature-based interventions for physical health conditions: A systematic review and meta-analysis
    Nicole A. Struthers, Nasimi A. Guluzade, Aleksandra A. Zecevic, David M. Walton, Anna Gunz
    Environmental Research.2024; 258: 119421.     CrossRef
  • Does Forest Contemplation Provide Greater Psychological Benefits than Passive Exposure to the Urban Forest? A Pilot Study
    Emilia Janeczko, Małgorzata Woźnicka, Katarzyna Śmietańska, Anna Wiśniewska, Natalia Korcz, Agata Kobyłka
    Forests.2024; 15(8): 1411.     CrossRef
  • The impact of forest therapy on functional recovery after acute ischemic stroke
    Sang-Hwa Lee, Jong-Hee Sohn, Joo Hye Sung, Sang-Won Han, Minwoo Lee, Yerim Kim, Jong Ho Kim, Jin Pyeong Jeon, Jae Jun Lee, Chulho Kim
    Urban Forestry & Urban Greening.2024; 101: 128537.     CrossRef
  • Waldtherapie zur Behandlung chronischer muskuloskelettaler Schmerzen: eine Pilotstudie
    Anika Schubert, Gabriele Röhrig-Herzog
    Zeitschrift für Komplementärmedizin.2024; 16(05): 56.     CrossRef
  • Health education via “empowerment” digital marketing of consumer products and services: Promoting therapeutic benefits of self-care for depression and chronic pain
    Jade L. Huntsman, Grzegorz Bulaj
    Frontiers in Public Health.2023;[Epub]     CrossRef
  • Posted Sentiments toward Experiences in Degraded Forests Are Shaped Jointly by Landscape Structure and Microclimate
    Qian He, Yue Wang, Quan Qiu, Yan Su, Hongxu Wei, Jiyue Li
    Ecosystem Health and Sustainability.2023;[Epub]     CrossRef
  • New Concept of Forest Medicine
    Qing Li
    Forests.2023; 14(5): 1024.     CrossRef
  • Virtual Forest Bathing Programming as Experienced by Disabled Adults with Mobility Impairments and/or Low Energy: A Qualitative Study
    Kirsten McEwan, Kari S. Krogh, Kim Dunlop, Mahnoor Khan, Alyssa Krogh
    Forests.2023; 14(5): 1033.     CrossRef
  • Indicators of the Psychosocial and Physiological Effects of Forest Therapy: A Systematic Review
    Hae-ryoung Chun, Yoon-Young Choi, Inhyung Cho, Hee-kyoung Nam, Geonwoo Kim, Sujin Park, Sung-il Cho
    Forests.2023; 14(7): 1407.     CrossRef
  • Effects of exercise therapy on pain and disability in patients with non-specific neck pain: A systematic review and meta-analysis
    Woon Su Cho, Chi Bok Park, Byeong Geun Kim
    Journal of Bodywork and Movement Therapies.2023; 36: 213.     CrossRef
  • Exercise-based rehabilitation in and with nature: a scoping review mapping available interventions
    Henriette Busk, Jonas Ahler, Alessio Bricca, Pætur Mikal Holm, Dorthe Varning Poulsen, Søren T. Skou, Lars Hermann Tang
    Annals of Medicine.2023;[Epub]     CrossRef
  • Healthy Dwelling: Design of Biophilic Interior Environments Fostering Self-Care Practices for People Living with Migraines, Chronic Pain, and Depression
    Dorothy Day Huntsman, Grzegorz Bulaj
    International Journal of Environmental Research and Public Health.2022; 19(4): 2248.     CrossRef
  • The Restorative Effects of Virtual Reality Forests on Elderly Individuals During the COVID-19 Lockdown
    Shaofeng Yuan, Futai Tao, Ying Li
    Journal of Organizational and End User Computing.2022; 34(6): 1.     CrossRef
  • Simulated Forest Immersion Therapy: Methods Development
    Amy Miner Ross, Reo Jane Francesca Jones
    International Journal of Environmental Research and Public Health.2022; 19(9): 5373.     CrossRef
  • Does Forest Therapy Have Physio-Psychological Benefits? A Systematic Review and Meta-Analysis of Randomized Controlled Trials
    Yunjeong Yi, Eunju Seo, Jiyeon An
    International Journal of Environmental Research and Public Health.2022; 19(17): 10512.     CrossRef
  • An Analysis of Theoretical Perspectives in Research on Nature-Based Interventions and Pain
    Reo J. F. Jones, Chloé O. R. Littzen
    International Journal of Environmental Research and Public Health.2022; 19(19): 12740.     CrossRef
  • YENİ BİR DOĞA-TEMELLİ TURİZM: ORMAN BANYOSU (SHİNRİN-YOKU) VE BİR ROTA ÖNERİSİ
    Banu KARAŞAH
    Turkish Journal of Forest Science.2022; 6(2): 553.     CrossRef
  • Forest Therapy Trails: A Conceptual Framework and Scoping Review of Research
    Paul H. Gobster, Courtney L. Schultz, Linda E. Kruger, John R. Henderson
    Forests.2022; 13(10): 1613.     CrossRef
  • Spending Time in the Forest or the Field: Investigations on Stress Perception and Psychological Well-Being—A Randomized Cross-Over Trial in Highly Sensitive Persons
    Katja Oomen-Welke, Evelyn Schlachter, Tina Hilbich, Johannes Naumann, Alexander Müller, Thilo Hinterberger, Roman Huber
    International Journal of Environmental Research and Public Health.2022; 19(22): 15322.     CrossRef
  • The Psychological and Physical Effects of Forests on Human Health: A Systematic Review of Systematic Reviews and Meta-Analyses
    Marita Stier-Jarmer, Veronika Throner, Michaela Kirschneck, Gisela Immich, Dieter Frisch, Angela Schuh
    International Journal of Environmental Research and Public Health.2021; 18(4): 1770.     CrossRef
  • The Effects of Mindfulness-Based Mandala Coloring, Made in Nature, on Chronic Widespread Musculoskeletal Pain: Randomized Trial
    Han Choi, Suk-Chan Hahm, Yo-Han Jeon, Jin-Woo Han, Soo-Yeon Kim, Jong-Min Woo
    Healthcare.2021; 9(6): 642.     CrossRef
  • Yeşil Egzersizin Kronik Ağrıya, Fiziksel ve Mental Sağlığa Etkileri
    Ebru DURUSOY, Rıfat MUTUŞ
    İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi.2021; (14): 351.     CrossRef
  • Exposure to greenspaces could reduce the high global burden of pain
    Jessica Stanhope, Martin F. Breed, Philip Weinstein
    Environmental Research.2020; 187: 109641.     CrossRef
  • The physiological and psychosocial effects of forest therapy: A systematic review
    Keeren Sundara Rajoo, Daljit Singh Karam, Mohd Zaki Abdullah
    Urban Forestry & Urban Greening.2020; 54: 126744.     CrossRef
  • Forest and Wellbeing: Bridging Medical and Forest Research for Effective Forest-Based Initiatives
    Ilaria Doimo, Mauro Masiero, Paola Gatto
    Forests.2020; 11(8): 791.     CrossRef
  • Effect of ice massage with integrated neuromuscular inhibition technique on pain and function in subjects with mechanical neck pain: randomized controlled trial
    Heba Mohammed Moselhy Al-Najjar, Amal Hassan Mohammed, Dalia Mohammed Mosaad
    Bulletin of Faculty of Physical Therapy.2020;[Epub]     CrossRef
  • Medical empirical research on forest bathing (Shinrin-yoku): a systematic review
    Ye Wen, Qi Yan, Yangliu Pan, Xinren Gu, Yuanqiu Liu
    Environmental Health and Preventive Medicine.2019;[Epub]     CrossRef
  • Health and well-being benefits of spending time in forests: systematic review
    Byeongsang Oh, Kyung Ju Lee, Chris Zaslawski, Albert Yeung, David Rosenthal, Linda Larkey, Michael Back
    Environmental Health and Preventive Medicine.2017;[Epub]     CrossRef
  • Shinrin-Yoku (Forest Bathing) and Nature Therapy: A State-of-the-Art Review
    Margaret M. Hansen, Reo Jones, Kirsten Tocchini
    International Journal of Environmental Research and Public Health.2017; 14(8): 851.     CrossRef
  • 7,565 View
  • 160 Download
  • 30 Web of Science
  • 33 Crossref
The Relationships Between Determination of Treatment Success and Emotional Factors in Patients With Chronic Musculoskeletal Pain
Tae Im Yi, Bo Kyoung Kim, Seung A Ha, Ji Young Lim
Ann Rehabil Med 2014;38(1):77-83.   Published online February 25, 2014
DOI: https://doi.org/10.5535/arm.2014.38.1.77
Objective

To investigate the relationship of the patient's criteria of successful treatment to emotional factors in patients with chronic musculoskeletal pain.

Methods

Patients who visited our outpatient hospital due to chronic musculoskeletal pain were evaluated using a questionnaire survey. Patients were evaluated with the Patient-Centered Outcomes Questionnaire (PCOQ) to investigate their expectation and criteria for success regarding treatment of chronic musculoskeletal pain. Beck Depression Inventory and State-Trait Anxiety Inventory were used to check for psychological variables. Correlations among each of the variables were evaluated statistically.

Results

Patients with higher levels of depression and anxiety needed larger improvements to consider the treatment as a success in the pain domain (depression, r=0.398, p=0.04; anxiety, r=0.447, p=0.02) and emotional distress domain (depression, r=0.617, p=0.001; anxiety, r=0.415, p=0.03), but had lower level of expectation of the treatment in the pain domain (depression, r=-0.427, p=0.01; anxiety, r=-0.441, p=0.004), emotional distress domain (depression, r=-0.454, p=0.01; anxiety, r=-0.395, p=0.04), and interference of daily activities domain (depression, r=-0.474, p=0.01; anxiety, r=-0.396, p=0.04). Patients were classified into 3 clusters based on the importance rating of each domain via a hierarchical analysis. The cluster of the patients with the higher rating of importance across all domains (importance of pain domain, 9.54; fatigue domain, 9.08; emotional distress domain, 9.23; interference of daily activities domain, 9.23) had the highest level of depression and anxiety.

Conclusion

Consideration of psychological factors, especially in patients who require larger improvements in all treatment domains, may be helpful for the successful treatment of chronic musculoskeletal pain.

Citations

Citations to this article as recorded by  
  • The Influence of Exercise Intensity on Psychosocial Outcomes in Musculoskeletal Disorders: A Systematic Review
    Sim Klaps, Sarah Haesevoets, Jeanine Verbunt, Albère Köke, Lotte Janssens, Annick Timmermans, Jonas Verbrugghe
    Sports Health: A Multidisciplinary Approach.2022; 14(6): 859.     CrossRef
  • Measurement of patients’ acceptable symptom levels and priorities for symptom improvement in advanced lung cancer
    Ellen Krueger, Ekin Secinti, Wei Wu, Nasser Hanna, Gregory Durm, Lawrence Einhorn, Shadia Jalal, Catherine E. Mosher
    Supportive Care in Cancer.2021; 29(10): 5895.     CrossRef
  • Factors underlying metastatic breast cancer patients' perceptions of symptom importance: a qualitative analysis
    C.E. Mosher, S. Daily, D. Tometich, M.S. Matthias, S.D. Outcalt, A. Hirsh, S.A. Johns, K. Rand, B. Schneider, L. Mina, A.M. Storniolo, E. Newton, K. Miller
    European Journal of Cancer Care.2018; 27(1): e12540.     CrossRef
  • Trastorno depresivo, trastorno de ansiedad y dolor crónico: múltiples manifestaciones de un núcleo fisiopatológico y clínico común
    Cesar A. Arango-Dávila, Hernán G. Rincón-Hoyos
    Revista Colombiana de Psiquiatría.2018; 47(1): 46.     CrossRef
  • Metastatic breast cancer patients’ expectations and priorities for symptom improvement
    Danielle B. Tometich, Catherine E. Mosher, Adam T. Hirsh, Kevin L. Rand, Shelley A. Johns, Marianne S. Matthias, Samantha D. Outcalt, Bryan P. Schneider, Lida Mina, Anna Maria V. Storniolo, Erin V. Newton, Kathy D. Miller
    Supportive Care in Cancer.2018; 26(11): 3781.     CrossRef
  • Depressive disorder, anxiety disorder and chronic pain: Multiple manifestations of a common clinical and pathophysiological core
    Cesar A. Arango-Dávila, Hernán G. Rincón-Hoyos
    Revista Colombiana de Psiquiatría (English ed.).2018; 47(1): 46.     CrossRef
  • Patient expectations for management of chronic non‐cancer pain: A systematic review
    Jose W. Geurts, Paul C. Willems, Craig Lockwood, Maarten van Kleef, Jos Kleijnen, Carmen Dirksen
    Health Expectations.2017; 20(6): 1201.     CrossRef
  • 4,790 View
  • 53 Download
  • 6 Web of Science
  • 7 Crossref
Randomized, Sham Controlled Trial of Transcranial Direct Current Stimulation for Painful Diabetic Polyneuropathy
Yon Joon Kim, Jeonghun Ku, Hyun Jung Kim, Dal Jae Im, Hye Sun Lee, Kyung Ah Han, Youn Joo Kang
Ann Rehabil Med 2013;37(6):766-776.   Published online December 23, 2013
DOI: https://doi.org/10.5535/arm.2013.37.6.766
Objective

To investigate the analgesic effect of transcranial direct current stimulation (tDCS) over the primary motor (M1), dorsolateral prefrontal cortex (DLPFC), and sham tDCS in patients with painful diabetic polyneuropathy (PDPN).

Methods

Patients with PDPN (n=60) were divided randomly into the three groups (n=20 per group). Each group received anodal tDCS with the anode centered over the left M1, DLPFC, or sham stimulation for 20 minutes at intensity of 2 mA for 5 consecutive days. A blinded physician rated the patients' pain using a visual analog scale (VAS), Clinical Global Impression (CGI) score, anxiety score, sleep quality, Beck Depression Inventory (BDI), and the pain threshold (PT) to pressure.

Results

After the tDCS sessions, the M1 group showed a significantly greater reduction in VAS for pain and PT versus the sham and DLPFC groups (p<0.001). The reduction in VAS for pain was sustained after 2 and 4 weeks of follow-up in the M1 group compared with the sham group (p<0.001, p=0.007). Significant differences were observed among the three groups over time in VAS for pain (p<0.001), CGI score (p=0.01), and PT (p<0.001). No significant difference was observed among the groups in sleep quality, anxiety score, or BDI score immediately after tDCS.

Conclusion

Five daily sessions of tDCS over the M1 can produce immediate pain relief, and relief 2- and 4-week in duration in patients with PDPN. Our findings provide the first evidence of a beneficial effect of tDCS on PDPN.

Citations

Citations to this article as recorded by  
  • Working memory ımprovement after transcranial direct current stimulation paired with working memory training ın diabetic peripheral neuropathy
    Serkan Aksu, Buse Rahime Hasırcı Bayır, Ceyhun Sayman, Ahmet Zihni Soyata, Gökalp Boz, Sacit Karamürsel
    Applied Neuropsychology: Adult.2025; 32(1): 231.     CrossRef
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    Andrew Flood, Rocco Cavaleri, We-Ju Chang, Jason Kutch, Constantino Toufexis, Simon J Summers
    Pain Medicine.2025; 26(2): 98.     CrossRef
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    Ping-Tao Tseng, Bing-Yan Zeng, Chih-Wei Hsu, Chao-Ming Hung, Brendon Stubbs, Yen-Wen Chen, Tien-Yu Chen, Jiann-Jy Chen, Wei-Te Lei, Yow-Ling Shiue, Chih-Sung Liang
    Journal of NeuroEngineering and Rehabilitation.2025;[Epub]     CrossRef
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    Li Li, Xueqin Luo, Yong Liu, Yongjie Jiang, Yankun Chen, Yangmei Chen, Jinping Wang
    Neurology and Therapy.2025;[Epub]     CrossRef
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    Ahmad Alipour, Roghayeh Mohammadi
    Neuroscience Letters.2024; 818: 137554.     CrossRef
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    Qiao Kong, Tingting Li, Sveta Reddy, Sierra Hodges, Jian Kong
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    Brain, Behavior, & Immunity - Health.2024; 35: 100723.     CrossRef
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    Yu-Jie Su, Pei-Lu Yi, Fang-Chia Chang
    Brain Sciences.2024; 14(1): 105.     CrossRef
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    Qiqi Wu, Xiaoyun Li, Yinhua Zhang, Shengxiong Chen, Richu Jin, Weiwei Peng
    Journal of Psychosomatic Research.2024; 185: 111868.     CrossRef
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    Yoeseph Cho, Seongeun Jeon, Yejin Lee, Hana Park, Yinglan Xu, Mijin Jeon, Sunmi Jung, Minyoung Kim, Ahlim Chin, Sang Sun Yoon, Junghyun Son
    Separations.2023; 10(7): 413.     CrossRef
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    L. Garcia-Larrea, N. André-Obadia, S. Rostaing, C. Colomb
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    Young-Ji Lee, Bong-Jo Kim, Cheol-Soon Lee, Boseok Cha, So-Jin Lee, Jae-Won Choi, Eunji Lim, Nuree Kang, Dongyun Lee
    Chronobiology in Medicine.2022; 4(4): 141.     CrossRef
  • Can a tDCS treatment enhance subjective and objective sleep among student-athletes?
    Jonathan Charest, Alexandre Marois, Celyne H. Bastien
    Journal of American College Health.2021; 69(4): 378.     CrossRef
  • Transcranial Direct Current Stimulation and Visual Illusion Effect According to Sensory Phenotypes in Patients With Spinal Cord Injury and Neuropathic Pain
    Dolors Soler, David Moriña, Hatice Kumru, Joan Vidal, Xavier Navarro
    The Journal of Pain.2021; 22(1): 86.     CrossRef
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    Sleep Medicine Reviews.2021; 55: 101381.     CrossRef
  • Towards the endotyping of the sleep–pain interaction: a topical review on multitarget strategies based on phenotypic vulnerabilities and putative pathways
    Alberto Herrero Babiloni, Gabrielle Beetz, Nicole K.Y. Tang, Raphael Heinzer, Jo Nijs, Marc O. Martel, Gilles J. Lavigne
    Pain.2021; 162(5): 1281.     CrossRef
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    Xiaoyun Li, Junjie Yao, Wenyun Zhang, Shengxiong Chen, Weiwei Peng
    Clinical Neurophysiology.2021; 132(9): 2163.     CrossRef
  • Transcranial direct current stimulation for provoked vestibulodynia: What roles do psychosexual factors play in treatment response?
    Mélanie Morin, Annie Morin, Véronique Gougeon, Serge Marchand, Guy Waddell, Yves-André Bureau, Isabelle Girard, Audrey Brassard, Justine Benoit-Piau, Guillaume Léonard
    Journal of Clinical Neuroscience.2021; 93: 54.     CrossRef
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    Stefano Giannoni-Luza, Kevin Pacheco-Barrios, Alejandra Cardenas-Rojas, Piero F. Mejia-Pando, Maria A. Luna-Cuadros, Judah L. Barouh, Marina Gnoatto-Medeiros, Ludmilla Candido-Santos, Alice Barra, Wolnei Caumo, Felipe Fregni
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    X. Moisset, M. Lanteri-Minet, D. Fontaine
    Journal of Neural Transmission.2020; 127(4): 673.     CrossRef
  • Transcranial direct current stimulation improves quality of life and physical fitness in diabetic polyneuropathy: a pilot double blind randomized controlled trial
    Galeno Ferreira, Edson Silva-Filho, Antônio de Oliveira, Clemilda de Lucena, Johnnatas Lopes, Rodrigo Pegado
    Journal of Diabetes & Metabolic Disorders.2020; 19(1): 327.     CrossRef
  • Anodal transcranial direct current stimulation over the primary motor cortex attenuates capsaicin‐induced dynamic mechanical allodynia and mechanical pain sensitivity in humans
    Sam W. Hughes, Grace Ward, Paul H. Strutton
    European Journal of Pain.2020; 24(6): 1130.     CrossRef
  • Noninvasive motor cortex stimulation effects on quantitative sensory testing in healthy and chronic pain subjects: a systematic review and meta-analysis
    Stefano Giannoni-Luza, Kevin Pacheco-Barrios, Alejandra Cardenas-Rojas, Piero F. Mejia-Pando, Maria A. Luna-Cuadros, Judah L. Barouh, Marina Gnoatto-Medeiros, Ludmilla Candido-Santos, Alice Barra, Wolnei Caumo, Felipe Fregni
    Pain.2020; 161(9): 1955.     CrossRef
  • Letter to the editor - Transcranial direct current stimulation improves quality of life and physical fitness in diabetic polyneuropathy: a pilot double blind randomized controlled trial”
    Satkarjit Kaur Jhandi, Nidhi Sharma, Manu Goyal
    Journal of Diabetes & Metabolic Disorders.2020; 19(2): 2025.     CrossRef
  • Age as a Mediator of tDCS Effects on Pain: An Integrative Systematic Review and Meta-Analysis
    Júlia Schirmer Saldanha, Maxciel Zortea, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo
    Frontiers in Human Neuroscience.2020;[Epub]     CrossRef
  • Non-invasive neuromodulation effects on painful diabetic peripheral neuropathy: a systematic review and meta-analysis
    Huiyan Zeng, Kevin Pacheco-Barrios, Ying Cao, Ying Li, Jinming Zhang, Caifeng Yang, Felipe Fregni
    Scientific Reports.2020;[Epub]     CrossRef
  • Role of the Prefrontal Cortex in Pain Processing
    Wei-Yi Ong, Christian S. Stohler, Deron R. Herr
    Molecular Neurobiology.2019; 56(2): 1137.     CrossRef
  • Primary Motor Cortex Transcranial Direct Current Stimulation Modulates Temporal Summation of the Nociceptive Withdrawal Reflex in Healthy Subjects
    Sam Hughes, Sybil Grimsey, Paul H Strutton
    Pain Medicine.2019; 20(6): 1156.     CrossRef
  • Latin American and Caribbean consensus on noninvasive central nervous system neuromodulation for chronic pain management (LAC2-NIN-CP)
    Abrahão Fontes Baptista, Ana Mércia B.L. Fernandes, Katia Nunes Sá, Alexandre Hideki Okano, André Russowsky Brunoni, Argelia Lara-Solares, Aziza Jreige Iskandar, Carlos Guerrero, César Amescua-García, Durval Campos Kraychete, Egas Caparelli-Daquer, Elias
    PAIN Reports.2019; 4(1): e692.     CrossRef
  • Transcranial Direct Current Stimulation to Improve the Dysfunction of Descending Pain Modulatory System Related to Opioids in Chronic Non-cancer Pain: An Integrative Review of Neurobiology and Meta-Analysis
    Maxciel Zortea, Leticia Ramalho, Rael Lopes Alves, Camila Fernanda da Silveira Alves, Gilberto Braulio, Iraci Lucena da Silva Torres, Felipe Fregni, Wolnei Caumo
    Frontiers in Neuroscience.2019;[Epub]     CrossRef
  • Non-invasive brain stimulation techniques for chronic pain
    Neil E O'Connell, Louise Marston, Sally Spencer, Lorraine H DeSouza, Benedict M Wand
    Cochrane Database of Systematic Reviews.2018;[Epub]     CrossRef
  • At-Home Transcranial Direct Current Stimulation (tDCS) With Telehealth Support for Symptom Control in Chronically-Ill Patients With Multiple Symptoms
    Alexa Riggs, Vaishali Patel, Bhaskar Paneri, Russell K. Portenoy, Marom Bikson, Helena Knotkova
    Frontiers in Behavioral Neuroscience.2018;[Epub]     CrossRef
  • Frequency‐dependent top‐down modulation of temporal summation by anodal transcranial direct‐current stimulation of the primary motor cortex in healthy adults
    S.W. Hughes, M. Ali, P. Sharma, N. Insan, P.H. Strutton
    European Journal of Pain.2018; 22(8): 1494.     CrossRef
  • Transcranial direct current stimulation for upper limb neuropathic pain: A double‐blind randomized controlled trial
    G.N. Lewis, D.A. Rice, M. Kluger, P.J. McNair
    European Journal of Pain.2018; 22(7): 1312.     CrossRef
  • Anodal Transcranial Direct Current Stimulation of the motor cortex reduces chronic pain in Alcock canal syndrome
    Raffaella Ricci, Ada Ghiggia, Ilenia La Rosa, Azzurra Milano, Walter Troni, Mark S. George, Jeffrey J. Borckardt, Lorys Castelli, Adriana Salatino
    Brain Stimulation.2018; 11(3): 648.     CrossRef
  • Non-invasive brain stimulation techniques for chronic pain
    Neil E O'Connell, Louise Marston, Sally Spencer, Lorraine H DeSouza, Benedict M Wand
    Cochrane Database of Systematic Reviews.2018;[Epub]     CrossRef
  • Emerging therapies for neuropathic pain: new molecules or new indications for old treatments?
    Didier Bouhassira, Nadine Attal
    Pain.2018; 159(3): 576.     CrossRef
  • Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS)
    Jean-Pascal Lefaucheur, Andrea Antal, Samar S. Ayache, David H. Benninger, Jérôme Brunelin, Filippo Cogiamanian, Maria Cotelli, Dirk De Ridder, Roberta Ferrucci, Berthold Langguth, Paola Marangolo, Veit Mylius, Michael A. Nitsche, Frank Padberg, Ulrich Pa
    Clinical Neurophysiology.2017; 128(1): 56.     CrossRef
  • Efficacy of transcranial direct-current stimulation in women with provoked vestibulodynia
    Annie Morin, Guillaume Léonard, Véronique Gougeon, Marie-Pierre Cyr, Guy Waddell, Yves-André Bureau, Isabelle Girard, Mélanie Morin
    American Journal of Obstetrics and Gynecology.2017; 216(6): 584.e1.     CrossRef
  • A Case of Long-Term Treatment of Chronic Pain Syndrome by Anodal tDCS of the Motor Cortex, Previously Resistant to High-Frequency rTMS and Implanted Spinal Cord Stimulation
    Hasan Hodaj, Jean-François Payen, Jean-Pascal Lefaucheur
    Brain Stimulation.2016; 9(4): 618.     CrossRef
  • Potential Mechanisms Supporting the Value of Motor Cortex Stimulation to Treat Chronic Pain Syndromes
    Marcos F. DosSantos, Natália Ferreira, Rebecca L. Toback, Antônio C. Carvalho, Alexandre F. DaSilva
    Frontiers in Neuroscience.2016;[Epub]     CrossRef
  • A Systematic Review on the Acceptability and Tolerability of Transcranial Direct Current Stimulation Treatment in Neuropsychiatry Trials
    Luana V.M. Aparício, Fabiana Guarienti, Lais Boralli Razza, André F. Carvalho, Felipe Fregni, André Russowsky Brunoni
    Brain Stimulation.2016; 9(5): 671.     CrossRef
  • Efficacy of transcranial direct-current stimulation (tDCS) in women with provoked vestibulodynia: study protocol for a randomized controlled trial
    Annie Morin, Guillaume Léonard, Véronique Gougeon, Guy Waddell, Yves-André Bureau, Isabelle Girard, Mélanie Morin
    Trials.2016;[Epub]     CrossRef
  • Effects of left primary motor and dorsolateral prefrontal cortex transcranial direct current stimulation on laser-evoked potentials in migraine patients and normal subjects
    Eleonora Vecchio, Katia Ricci, Anna Montemurno, Marianna Delussi, Sara Invitto, Marina de Tommaso
    Neuroscience Letters.2016; 626: 149.     CrossRef
  • A comprehensive database of published tDCS clinical trials (2005–2016)
    Jean-Pascal Lefaucheur
    Neurophysiologie Clinique/Clinical Neurophysiology.2016; 46(6): 319.     CrossRef
  • Cortical neurostimulation for neuropathic pain
    Jean-Pascal Lefaucheur
    Pain.2016; 157(Supplement): S81.     CrossRef
  • Repetitive transcranial magnetic stimulation and transcranial direct-current stimulation in neuropathic pain due to radiculopathy
    Nadine Attal, Samar S. Ayache, Daniel Ciampi De Andrade, Alaa Mhalla, Sophie Baudic, Frédérique Jazat, Rechdi Ahdab, Danusa O. Neves, Marc Sorel, Jean-Pascal Lefaucheur, Didier Bouhassira
    Pain.2016; 157(6): 1224.     CrossRef
  • Transcranial direct current stimulation as a tool in the study of sensory-perceptual processing
    Thiago L. Costa, Olivia M. Lapenta, Paulo S. Boggio, Dora F. Ventura
    Attention, Perception, & Psychophysics.2015; 77(6): 1813.     CrossRef
  • Effects of Transcranial Direct Current Stimulation (tDCS) on Pain Distress Tolerance: A Preliminary Study
    Timothy Y. Mariano, Mascha van't Wout, Benjamin L. Jacobson, Sarah L. Garnaat, Jason L. Kirschner, Steven A. Rasmussen, Benjamin D. Greenberg
    Pain Medicine.2015; 16(8): 1580.     CrossRef
  • Transcranial Direct Current Stimulation (tDCS) Targeting Left Dorsolateral Prefrontal Cortex Modulates Task-Induced Acute Pain in Healthy Volunteers
    Timothy Y. Mariano, Mascha van’t Wout, Sarah L. Garnaat, Steven A. Rasmussen, Benjamin D. Greenberg
    Pain Medicine.2015; : pnv042.     CrossRef
  • Patient-conducted anodal transcranial direct current stimulation of the motor cortex alleviates pain in trigeminal neuralgia
    Tim Hagenacker, Vera Bude, Steffen Naegel, Dagny Holle, Zaza Katsarava, Hans-Christoph Diener, Mark Obermann
    The Journal of Headache and Pain.2014;[Epub]     CrossRef
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Screening Test for Depression Using the SF-36 Health Survey in Patients with Chronic Musculoskeletal Pain.
Kim, Dong Hyun , Kim, Tae Hoon , Kim, Jun Lae , Lee, Hyuck , Kim, Soo A , Oh, Ki Young
J Korean Acad Rehabil Med 2007;31(4):434-439.
Objective
To evaluate the usefulness of the mental component summary (MCS) from the short form 36-item health survey (SF-36) as a screening test for depression in patients with chronic musculoskeletal pain and identify the optimal cut-off value that predicts a positive depression score measured by the center for epidemiological study depression survey (CES-D). Method: This study was designed as a questionnaire survey. 502 patients who visited our outpatient clinics due to chronic musculoskeletal pain were evaluated. They completed the SF-36 and the CES-D. The correlation between the MCS score from the SF-36 and the CES-D was identified, and also the cut-off value of the MCS score was determined with ROC curves used the CES-D as the standard measure for depression. The MCS scores were compared according to age, sex, duration of diseases, diagnosis, and the presence of depression. Results: The mean overall score of CES-D and the MCS score were 17.5±10.2, 52.2±16.4 respectively. The MCS scores negatively correlated with the CES-D (γ=-0.879, p<0.01). There were no significant differences of the MCS scores in each group according to age, sex, duration of diseases, and diagnosis (p>0.05). However, patients with depression had significantly lower MCS scores than patients without depression (p<0.05). The cut-off value was 42.4 with 88.1% of sensitivity and 92.6% of specificity. Conclusion: The MCS scores would be useful screening test for depression with cut-off value of 42.4 that predicts the closest result of the CES-D. (J Korean Acad Rehab Med 2007; 31: 434-439)
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Chronic Pain and Psychosocial Functions in Adults with Athetoid Cerebral Palsy.
Park, Eun Sook , Park, Chang Il , Cho, Sung Rae , Kim, Eun Joo , Moon, Ja Young
J Korean Acad Rehabil Med 2002;26(4):391-397.

Objective: To evaluate the effect of chronic pain on psychosocial functions in adults with athetoid cerebral palsy.

Method: Thirty-five adults with athetoid cerebral palsy were recruited as subjects, then the radiologic and electrodiagnostic studies were assessed. The characteristics of pain in severity and disability status with Von Korff's chronic pain grade classification system and psychosocial functional status using affect balance scale, Beck depression inventory, social adjustment scale and satisfaction with life scale were evaluated.

Results: Twenty-eight (80.0%) subjects had the pain lasting more than 3 months. The mean score of characteristic pain intensity was 65.5⁑11.5. Eleven subjects (31.4%) showed both abnormal radiologic and electrodiagnostic findings, and these subjects had higher disability score among the subjects who complaint of chronic pain (p<0.05). The pain intensity had significant relationship with negative affects such as depression and dissatisfaction with life style (p<0.05). In addition, social adjustment tended to be lower in subjects with severe chronic pain.

Conclusion: Chronic pain was commonly observed in adults with athetoid cerebral palsy, and the pain adversely affected psychosocial functions. Therefore, proper management of chronic pain might be helpful for enhancing their psychosocial functions in these subjects. (J Korean Acad Rehab Med 2002; 26: 391-397)

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Influencing Psychologic Factors and Stress in Patients with Chronic Pain.
Kim, Sei Joo , Kim, Woo Sub , Kang, Yoon Kyoo , Lee, Sang Heon , Cho, Sook Haeng
J Korean Acad Rehabil Med 2000;24(6):1161-1167.

Objective: To investigate the influence of psychologic factors and stress on chronic pain syndrome and predictive factors of chronic pain.

Method: The subjects were 23 patients with chronic pain. The age was ranged from 25 to 66 years with an average of 45. We measured pain with initial visual analogue scale (VAS), one-week total VAS, and tenderness threshold by pressure algometer. We evaluated the degree of depression, anxiety and disability with chronic pain and the impact of stress of major versus minor daily events. Association between degree of pain and psychologic factors was studied by regression and stress of major versus minor daily events by correlation analysis. Predictive factors for chronic pain were determined by multiple regression analysis. Association of daily fluctuation of pain severity and stress from minor life events was also studied.

Results: One-week total VAS was associated with initial VAS (r=0.601, p<0.05). Initial VAS had association with depression and anxiety. Predictive factors for one-week total VAS were initial VAS, static anxiety, and pain disability (r=0.624, p<0.05).

Conclusion: Depression, anxiety, pain disability from chronic pain, and stress were major influencing factors in patients with chronic pain.

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