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"Atlantoaxial joint"

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"Atlantoaxial joint"

Case Reports
Grisel Syndrome: Pathophysiological Evidence from Magnetic Resonance Imaging Findings
See-Hyun Park, Sung-Hee Park, Sang-Hee Lee
Ann Rehabil Med 2013;37(5):713-716.   Published online October 29, 2013
DOI: https://doi.org/10.5535/arm.2013.37.5.713

Grisel syndrome is a condition of uncertain etiology characterized by a non-traumatic atlantoaxial subluxation following an infection in the head and neck region. Although first described in 1830, the exact pathophysiology of Grisel syndrome remains unclear. We present a case of atlantoaxial subluxation after acute lymphadenitis diagnosed with a dynamic computed tomography (CT) and magnetic resonance imaging (MRI). A previously healthy 9-year-old male patient presented with torticollis of sudden onset. Dynamic CT and MR imaging showed rotary atlantoaxial subluxation and inflammation surrounding the cervical spinal ligaments. A follow-up MRI of the cervical spine, taken 3 weeks after the onset of symptoms, showed a complete resolution of subluxation and inflammation surrounding the cervical spinal ligaments. In this case report, we support the hypothesis that an inflammation-induced laxity of the cervical ligaments is the pathologic key to Grisel syndrome using radiologic findings.

Citations

Citations to this article as recorded by  
  • Predictors of clinically significant underlying etiologies in children presenting with torticollis
    Matan Shemer, Shai Noyman, Ayelet Rimon, Neta Cohen
    Paediatrics & Child Health.2026; 31(2): 111.     CrossRef
  • Usefulness of CT-like Bone Contrast MRI in the Treatment of Atlantoaxial Rotatory Fixation
    Yutaka Kinoshita, Toshinori Sakai, Shoichiro Takao, Akihiro Nagamachi, Yasuhiro Takahashi, Koichi Sairyo
    JBJS Case Connector.2026;[Epub]     CrossRef
  • Torticollis in a child with Grisel syndrome: A case report and review of the literature
    Bishal Budha, Sujan Paudel, Prajjwol Luitel, Bishweshwar Joshi, Arun Upreti, Nischal Ghimire
    International Journal of Surgery Case Reports.2025;[Epub]     CrossRef
  • Das Grisel-Syndrom – häufiger als gedacht?
    Jani Puhakka, Gregor Fischer, Alexander Küffer, Markus Loibl, Tamás Fekete, Dezsö Jeszenszky, Daniel Haschtmann
    Die Wirbelsäule.2025; 09(04): 203.     CrossRef
  • Diagnostic Approach and Treatment Options for Pediatric Cases of Grisel’s Syndrome Post Otolaryngology Procedure: A Systematic Review
    Omair H Al-Hussain, Ghadah Al-Hussain
    Cureus.2024;[Epub]     CrossRef
  • A Case Report of Grisel’s Syndrome Complicating the Postoperative Course of Craniotomy for a Massive Cystic Brain Lesion
    Takara R Newsome-Cuby, Kwadwo Darko, Peace Odiase, Sean O'Leary, Charles Marchese, Michael J Valentine, Benjamin Pautler, Usama AlDallal, Mohamed Ismail, Fakhar Hayat
    Cureus.2024;[Epub]     CrossRef
  • A Case of Grisel’s Syndrome After Tonsillectomy and Adenoidectomy
    Sea Eun Yi, Yoo-Sam Chung
    Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2022; 65(9): 533.     CrossRef
  • Magnetic Resonance Imaging as the Primary Imaging Modality in Children Presenting with Inflammatory Nontraumatic Atlantoaxial Rotatory Subluxation
    Katharina J. Wenger, Elke Hattingen, Luciana Porto
    Children.2021; 8(5): 329.     CrossRef
  • Atlantoaxial Rotatory Subluxation: A Rare Complication of Craniofacial Surgery
    Viren Patel, Robin Yang, Sameer Shakir, Mari Groves, Scott P. Bartlett
    Journal of Craniofacial Surgery.2020; 31(1): 166.     CrossRef
  • Occipital condyle syndrome in a case of rotatory atlantoaxial subluxation (type II) with craniovertebral junction tuberculosis: Should we operate on “active tuberculosis?”
    Ashutosh Kumar, Suyash Singh, Priyadarshi Dikshit, KuntalKanti Das, ArunKumar Srivastava
    Journal of Craniovertebral Junction and Spine.2020; 11(2): 143.     CrossRef
  • Grisel’s Syndrome in Children: Two Case Reports and Systematic Review of the Literature
    Nicole Pini, Martina Ceccoli, Patrizia Bergonzini, Lorenzo Iughetti, Piero Pavone
    Case Reports in Pediatrics.2020; 2020: 1.     CrossRef
  • Atlantoaxial subluxation in the pediatric patient: Case series and literature review
    Catherine A Mazzola, Catherine Christie, Isabel A Snee, Hamail Iqbal
    Journal of Neuroscience and Neurological Disorders.2020; 4(2): 069.     CrossRef
  • Grisel’s syndrome associated with tonsillitis
    Mahmoud Khodabandeh, Saeed Shakiba, Soroosh Alizadeh, Hamid Eshaghi
    IDCases.2019; 15: e00470.     CrossRef
  • Grisel Syndrome in Pediatric Age: A Single-Center Italian Experience and Review of the Literature
    Pasquale Anania, Piero Pavone, Mattia Pacetti, Monica Truffelli, Marco Pavanello, Marcello Ravegnani, Alessandro Consales, Armando Cama, Gianluca Piatelli
    World Neurosurgery.2019; 125: 374.     CrossRef
  • Interventional magnetic resonance imaging as a diagnostic and therapeutic method in treating acute pediatric atlantoaxial rotatory subluxation
    Juuli Hannonen, Marja Perhomaa, Niina Salokorpi, Willy Serlo, Roberto Sequeiros, Jaakko Sinikumpu
    Experimental and Therapeutic Medicine.2019;[Epub]     CrossRef
  • Craniovertebral Junction Abnormalities in Surgical Patients With Congenital Muscular Torticollis
    Ah-Reum Ahn, Ueon Woo Rah, Ji-Eun Woo, Sunghoon Park, Sanghyun Kim, Shin-Young Yim
    Journal of Craniofacial Surgery.2018; 29(3): e327.     CrossRef
  • A Case of Grisel Syndrome Showing No Underlying Laxity of the Atlanto-axial Joint
    Ah-Reum Ahn, Yul-Hyun Park, Eun Ji Park, Shin-Young Yim
    Annals of Rehabilitation Medicine.2017; 41(3): 511.     CrossRef
  • Torticollis in Children
    Anne Filleron, Mohamed L’Kaissi, Jérôme Cottalorda, Eric Jeziorski, Michel Rodière, Olivier Prodhomme, Tu Anh Tran
    Clinical Pediatrics.2016; 55(5): 459.     CrossRef
  • Akuter Schiefhals oder Grisel-Syndrom
    B. Schulze, L. Beyer
    Manuelle Medizin.2016; 54(4): 251.     CrossRef
  • Case Report of Atlantoaxial Rotatory Fixation after Cochlear Implantation
    Takahiro Nakashima, Keiji Matsuda, Takumi Okuda, Tetsuya Tono, Minoru Takaki, Tamon Hayashi, Yutaka Hanamure
    Case Reports in Otolaryngology.2016; 2016: 1.     CrossRef
  • Tortícolis muscular congénito
    P. Peyrou, Y. Lefèvre
    EMC - Aparato Locomotor.2015; 48(2): 1.     CrossRef
  • Cervical Traction for the Treatment of Spinal Injury and Deformity
    Joanne H. Wang, Alan H. Daniels, Mark A. Palumbo, Craig P. Eberson
    JBJS Reviews.2014;[Epub]     CrossRef
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Cervical Myelopathy from Atlantoaxial Instability in a Child with Down Syndrome and Cerebral Palsy: A case report.
Kim, Min Young , Kim, Sung Hyun
J Korean Acad Rehabil Med 2008;32(2):230-233.
The development of nontraumatic atlantoaxial instability in children with Down syndrome has been well documented. Even though the incidence of symptomatic myelopathy from atlantoaxial instability is quite low, early recognition has tremendous significance to reduce the chance of progressing into life threatening conditions. Recently we experienced a case with atlantoaxial instability in a Down syndrome patient who was also diagnosed as cerebral palsy and subsequently in a quadriplegic state. Since neurologic changes from cord compression are difficult to recognize in this kind of complicated case, special attention should be paid to prevent catastrophic events. (J Korean Acad Rehab Med 2008; 32: 230-233)
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  • 13 Download
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