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"Yunsoo Soh"

Clinical Practice Guideline

Clinical Practice Guidelines for Diagnosis and Non-Surgical Treatment of Primary Frozen Shoulder
Byung Chan Lee, Beom Suk Kim, Byeong-Ju Lee, Chang-Won Moon, Chul-Hyun Park, Dong Hwan Kim, Dong Hwan Yun, Donghwi Park, Doo Young Kim, Du Hwan Kim, Gi-Wook Kim, Hyun Jung Kim, Il-Young Jung, In Jong Kim, Jae Hyeon Park, Jae-Hyun Lee, Jaeki Ahn, Jae-Young Lim, Jin A Yoon, Jong Hwa Lee, Jong-Moon Hwang, Keewon Kim, Kyeong Eun Uhm, Kyoung Hyo Choi, Kyung Eun Nam, Kyunghoon Min, Min Cheol Chang, Myung Woo Park, Nackhwan Kim, Hyeng-Kyu Park, Seong Hun Kim, Seoyon Yang, Sun Jae Won, Sung Gyu Moon, Sung Joon Chung, Sungju Jee, Woo Hyung Lee, Yong Bok Park, Yoonju Na, Yu Hui Won, Yu Jin Im, Yu Sung Yoon, Yun Jung Lee, Yunsoo Soh, Jae-Young Han
Ann Rehabil Med 2025;49(3):113-138.   Published online June 30, 2025
DOI: https://doi.org/10.5535/arm.250057
Objective
Primary frozen shoulder causes significant pain and progressively restricts shoulder movements. Diagnosis is primarily clinically based on patient history and physical examination. Management is mainly non-invasive owing to its self-limiting clinical course. However, clinical practice guidelines for frozen shoulder have not yet been developed in Korea. The developed guidelines aim to provide evidence-based recommendations for the diagnosis and treatment of frozen shoulder.
Methods
A guideline development committee reviewed the literature from four databases (PubMed, Embase, Cochrane Library, and KMbase). Using the PICO (Population, Intervention, Comparator, and Outcome) framework, the committee formulated two backgrounds and 16 key questions to address common clinical concerns. Recommendations were made using the Grading of Recommendations, Assessment, Development, and Evaluation framework.
Results
Diabetes, thyroid disease, and dyslipidemia significantly increase the risk of developing a frozen shoulder. Although frozen shoulder is often self-limiting, some patients may experience long-term disabilities. Ultrasound and magnetic resonance imaging should be used as adjunctive tools alongside clinical diagnosis, and not as independent diagnostic methods. Noninvasive approaches, such as medications, physical modalities, exercises, electrical stimulation, and manual therapy, may reduce pain and improve shoulder function. Other noninvasive interventions have limited evidence, and their application should be based on clinical judgment. Intra-articular steroid injections are recommended for treatment, and physiotherapy or hydrodilatation with steroid injections can also be beneficial.
Conclusion
These guidelines provide evidence-based recommendations for diagnosing and treating primary frozen shoulder.

Citations

Citations to this article as recorded by  
  • Comparison of efficacy of intra-articular injection of platelet-rich plasma with bupivacaine and steroid combination in chronic shoulder pain
    Naveen Malhotra, Neha Sinha, Amit Kumar, Ritu, Disha Gupta, Naman Malhotra
    Journal of Anaesthesiology Clinical Pharmacology.2026; 42(1): 120.     CrossRef
  • Hyperlipidemia exacerbates frozen shoulder fibrosis by activating the TGF-β/Smad2/3 signaling pathway via the TBX5-TNC-Itgα2 axis
    Fan Jiang, Yi Zhang, Jinlong Ma, Tengbo Yu, Youliang Shen
    iScience.2026; 29(2): 114660.     CrossRef
  • Axillary recess capsular edema is associated with heterogeneity in rehabilitation response: Implications for a magnetic resonance imaging-based stratified treatment strategy for adhesive capsulitis
    De-Ting Zhu, Yan-Qi Shan, Yan Wang, ChenChen, Da-Dong Zhang, Xiu-Li Kan, Quan-Bing Zhang, Xue-Ming Li, Yun Zhou
    Archives of Physical Medicine and Rehabilitation.2026;[Epub]     CrossRef
  • Clinical efficacy of Mulligan mobilization with movement versus proprioceptive neuromuscular facilitation on pain reduction and shoulder mobility in patients with frozen shoulder
    Sylejman Miftari, Mejdi Aliu
    Health, sport, rehabilitation.2026;[Epub]     CrossRef
  • 27,985 View
  • 890 Download
  • 2 Web of Science
  • 4 Crossref
Original Articles
Association Between Asymmetry in Knee Extension Strength and Balance in a Community-Dwelling Elderly Population: A Cross-Sectional Analysis
Jinmann Chon, Hee-Sang Kim, Jong Ha Lee, Seung Don Yoo, Dong Hwan Yun, Dong Hwan Kim, Seung Ah Lee, Yoo Jin Han, Yunsoo Soh, Yong Kim, Young Rok Han, Chang Won Won, Seonyoung Han
Ann Rehabil Med 2018;42(1):113-119.   Published online February 28, 2018
DOI: https://doi.org/10.5535/arm.2018.42.1.113
Objective

To evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population.

Methods

The strength of the knee extensors in each leg was measured in 306 community-dwelling elderly subjects (age, 76.70±4.85 years) and 25 young healthy subjects (age, 34.23±8.93 years). Based on the difference in strength of both legs, the elderly subjects were divided into symmetric (n=128) and asymmetric (n=178) strength groups using an asymmetry cutoff 20%. We determined the postural control ability of the subjects using InBody posturography, Berg Balance Scale (BBS), Timed Up and Go test (TUG) and Short Physical Performance Battery (SPPB). The sway index (SI) of the subjects in four positions was assessed using posturography.

Results

The group with asymmetric strength presented a significantly higher SI than the group with symmetric strength, in the normal position with eyes open and eyes open on pillows. In the normal position with the eyes closed and in postures with the eyes closed on pillows, the statistical analysis revealed no significant differences between the two groups. The three tests for physical performance (BBS, TUG, and SPPB) show no statistically significant difference between the two groups.

Conclusion

The asymmetric strength group showed a significantly lower balance than the group with symmetric strength based on several posturographic parameters. Ambulatory elderly individuals with asymmetry in knee extension strength, showed deficits in balance control even in normal clinical tests.

Citations

Citations to this article as recorded by  
  • Degenerative Hip Osteoarthritis in Unilateral Knee Osteoarthritis Patients: A Correlation Analysis
    Juncheng Li, Wenrun Zhu, Jun Yang, Xinhao Niu, Han Tang, Lu Cao, Changan Guo
    Orthopaedic Surgery.2025; 17(4): 1201.     CrossRef
  • Effects of high-intensity interval robot-assisted gait training on cardiopulmonary function and walking ability in chronic stroke survivors: A multicenter single-blind randomized controlled trial
    Junghwa Do, Woo-Taek Lim, Dae Yul Kim, Eun Jae Ko, Myoung-Hwan Ko, Geon Woo Kim, Ji Hye Kim, SooBin Kim, Hwal Kim
    Journal of Back and Musculoskeletal Rehabilitation.2024; 37(5): 1309.     CrossRef
  • Smartphone Assessment of the Sitting Heel-Rise Test
    Gustavo O. Hoffmann, Edilson Borba, Eduardo H. Casarotto, Gisele Francine Devetak, Ramzi Jaber, John G. Buckley, André L. F. Rodacki
    Sensors.2024; 24(18): 6036.     CrossRef
  • Leg skeletal muscle mass asymmetry is independently associated with gait speed in older adults requiring long‐term care
    Ryo Sato, Yohei Sawaya, Masahiro Ishizaka, Takahiro Shiba, Tamaki Hirose, Tomohiko Urano
    Geriatrics & Gerontology International.2023; 23(5): 371.     CrossRef
  • Age-Related Differences in Intermuscular Coherence EMG-EMG of Ankle Joint Antagonist Muscle Activity during Maximal Leaning
    Mariusz Konieczny, Przemysław Domaszewski, Elżbieta Skorupska, Zbigniew Borysiuk, Kajetan J. Słomka
    Sensors.2022; 22(19): 7527.     CrossRef
  • Body Composition Symmetry in Long-Term Active Middle-Aged and Older Individuals
    Silvia Stagi, Alessia Moroni, Margherita Micheletti Cremasco, Elisabetta Marini
    International Journal of Environmental Research and Public Health.2021; 18(11): 5956.     CrossRef
  • Does piriformis muscle syndrome impair postural balance? A case control study
    Mariem Jardak, Fatma Chaari, Fatma Bouchaala, Thouraya Fendri, Mohammed Achraf Harrabi, Haithem Rebai, Sonia Sahli
    Somatosensory & Motor Research.2021; 38(4): 315.     CrossRef
  • Effect of improvement in quadriceps strength asymmetry on trunk movement asymmetry after total knee arthroplasty
    Yoshinori Hiyama, Tsuyoshi Asai, Osamu Wada
    Gait & Posture.2020; 79: 21.     CrossRef
  • Recovery of mobility function and life-space mobility after ischemic stroke: the MOBITEC-Stroke study protocol
    R. Rössler, S. A. Bridenbaugh, S. T. Engelter, R. Weibel, D. Infanger, E. Giannouli, A. Sofios, L. Iendra, E. Portegijs, T. Rantanen, L. Streese, H. Hanssen, R. Roth, A. Schmidt-Trucksäss, N. Peters, T. Hinrichs
    BMC Neurology.2020;[Epub]     CrossRef
  • The Effect of Exercise Training on Gait, Balance, and Physical Fitness Asymmetries in Persons With Chronic Neurological Conditions: A Systematic Review of Randomized Controlled Trials
    John W. Farrell, Jordan Merkas, Lara A. Pilutti
    Frontiers in Physiology.2020;[Epub]     CrossRef
  • Trunk movement asymmetry associated with pain, disability, and quadriceps strength asymmetry in individuals with knee osteoarthritis: a cross-sectional study
    H. Iijima, R. Eguchi, T. Aoyama, M. Takahashi
    Osteoarthritis and Cartilage.2019; 27(2): 248.     CrossRef
  • 8,376 View
  • 84 Download
  • 11 Web of Science
  • 11 Crossref
Association Between a Polymorphism in CASP3 and CASP9 Genes and Ischemic Stroke
Bae Youl Lee, Jinmann Chon, Hee-Sang Kim, Jong Ha Lee, Dong Hwan Yun, Seung Don Yoo, Dong Hwan Kim, Seung Ah Lee, Yoo Jin Han, Hyunseok Lee, Jin Chul Kim, Yunsoo Soh, Joo-Ho Chung, Su Kang Kim, Hae Jeong Park
Ann Rehabil Med 2017;41(2):197-203.   Published online April 27, 2017
DOI: https://doi.org/10.5535/arm.2017.41.2.197
Objective

To investigate whether the polymorphisms of CASP3 gene (rs4647602, intron A/C and rs1049216, UTR C/T) and CASP9 gene (rs1052576, Gln/Arg G/A and rs1052571, Ser/Val T/C) were associated with the development, and clinical severity of ischemic stroke and functional consequences after stroke.

Methods

Genomic DNA from 121 ischemic stroke patients and 201 healthy control subjects were extracted, and polymerase chain reaction products were sequenced. To investigate the association of polymorphisms and the development, and National Institutes of Health Stroke Scale (K-NIHSS), logistic regression models were analyzed.

Results

Polymorphism of the untranslational region of CASP3 (rs1049216, UTR C/T) has been associated with the development of ischemic stroke—in codominant1 model (odds ratio [OR], 0.51; 95% confidence interval [CI], 0.29–0.88; p=0.017), in dominant model (OR, 0.57; 95% CI, 0.34–0.97; p=0.034), and in the overdominant model (OR, 0.50; 95% CI, 0.29–0.87; p=0.011). A missense SNP of CASP9 gene (rs1052571, Ser/Val T/C) was associated with the development of ischemic stroke (OR, 1.93; 95% CI, 1.05–3.55; p=0.034 in recessive model).

Conclusion

These results indicate the possibility that CASP3 and CASP9 genes are markers for the development of ischemic stroke.

Citations

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  • Genetic Associations of Clonal Hematopoiesis With Cardioembolic Stroke: Insights From Genome‐Wide Mendelian Randomization, Bulk RNA, Single‐Cell RNA Sequencing
    Haozhou Tan, Feng Zhu, Han Yan, Fangfang Li, Yang Yao, Ying Li, Qian Feng
    CNS Neuroscience & Therapeutics.2025;[Epub]     CrossRef
  • Very early environmental enrichment protects against apoptosis and improves functional recovery from hypoxic–ischemic brain injury
    Hoo Young Lee, Suk-Young Song, Jihye Hwang, Ahreum Baek, Dawoon Baek, Sung Hoon Kim, Jung Hyun Park, Sungchul Choi, Soonil Pyo, Sung-Rae Cho
    Frontiers in Molecular Neuroscience.2023;[Epub]     CrossRef
  • Pathogen-driven nucleotide overload triggers mitochondria-centered cell death in phagocytes
    Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel, Anders P. Hakansson
    PLOS Pathogens.2023; 19(12): e1011892.     CrossRef
  • Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts
    Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Dere
    Journal of Thrombosis and Haemostasis.2022; 20(10): 2255.     CrossRef
  • Integrated LC-MS/MS Method and Network Pharmacology for Exploring the Mechanism of Neuroprotective Effect of Ginsenoside Rc in Oxygen-Glucose Deprivation/Reperfusion Injury
    Mingmin Huang, Shaoru Chen, Kening Zheng, Qu Liu, Kening Li, Minghua Xian, Shumei Wang
    Revista Brasileira de Farmacognosia.2021; 31(2): 207.     CrossRef
  • Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease
    Maria I. Avrutsky, Carol M. Troy
    Frontiers in Pharmacology.2021;[Epub]     CrossRef
  • To explore the Radix Paeoniae Rubra-Flos Carthami herb pair's potential mechanism in the treatment of ischemic stroke by network pharmacology and molecular docking technology
    Xingyu Chen, Yue Wang, Ying Ma, Ruonan Wang, Dexi Zhao
    Medicine.2021; 100(49): e27752.     CrossRef
  • Association Study of the Caspase Gene Family and Psoriasis Vulgaris Susceptibility in Northeastern China
    Xinyu Yao, Siyu Hao, Pei Yu
    BioMed Research International.2019; 2019: 1.     CrossRef
  • A multi-ancestry genome-wide study incorporating gene–smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
    Yun Ju Sung, Lisa de las Fuentes, Thomas W Winkler, Daniel I Chasman, Amy R Bentley, Aldi T Kraja, Ioanna Ntalla, Helen R Warren, Xiuqing Guo, Karen Schwander, Alisa K Manning, Michael R Brown, Hugues Aschard, Mary F Feitosa, Nora Franceschini, Yingchang
    Human Molecular Genetics.2019; 28(15): 2615.     CrossRef
  • 7,392 View
  • 44 Download
  • 9 Web of Science
  • 9 Crossref
The Relationship Between Tongue Pressure and Oral Dysphagia in Stroke Patients
Jong Ha Lee, Hee-Sang Kim, Dong Hwan Yun, Jinmann Chon, Yoo Jin Han, Seung Don Yoo, Dong Hwan Kim, Seung Ah Lee, Hye In Joo, Ji-su Park, Jin Chul Kim, Yunsoo Soh
Ann Rehabil Med 2016;40(4):620-628.   Published online August 24, 2016
DOI: https://doi.org/10.5535/arm.2016.40.4.620
Objective

To evaluate the relationships between tongue pressure and different aspects of the oral-phase swallowing function.

Methods

We included 96 stroke patients with dysphagia, ranging in age from 40 to 88 years (mean, 63.7 years). Measurements of tongue pressure were obtained with the Iowa Oral Performance Instrument, a device with established normative data. Three trials of maximum performance were performed for lip closure pressure (LP), anterior hard palate-to-tongue pressure (AP), and posterior hard palate-to-tongue pressure (PP); buccal-to-tongue pressures on both sides were also recorded (buccal-to-tongue pressure, on the weak side [BW]; buccal-to-tongue pressure, on the healthy side [BH]). The average pressure in each result was compared between the groups. Clinical evaluation of the swallowing function was performed with a videofluoroscopic swallowing study.

Results

The average maximum AP and PP values in the intact LC group were significantly higher than those in the inadequate lip closure group (AP, p=0.003; PP, p<0.001). AP and PP showed significant relationships with bolus formation (BF), mastication, premature bolus loss (PBL), tongue to palate contact (TP), and oral transit time (OTT). Furthermore, LP, BW, and BH values were significantly higher in the groups with intact mastication, without PBL and intact TP.

Conclusion

These findings indicate that the tongue pressure appears to be closely related to the oral-phase swallowing function in post-stroke patients, especially BF, mastication, PBL, TP and OTT.

Citations

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    Shu‐Hua Kao, Hsin Chu, Kondwani Joseph Banda, Chien‐Mei Sung, Ruey Chen, Li‐Fang Chang, Kai‐Jo Chiang, Li‐Chung Pien, Kuei‐Ru Chou
    Journal of Oral Rehabilitation.2026; 53(2): 402.     CrossRef
  • Increasing tongue pressure with CAD/CAM palatal augmentation plate for tongue cancer patients with glossectomy
    Yi-Fang Huang, Chih-Hung Lin, Yu-Fang Liao, Wei‐Han Chang
    Supportive Care in Cancer.2026;[Epub]     CrossRef
  • Textural considerations in the design of transitional foods for dysphagia
    Suk Meng Goh, Katsuyoshi Nishinari, Seh Ling Kwong
    Translational Food Sciences.2026;[Epub]     CrossRef
  • Optimized transcranial direct current stimulation for post-stroke dysphagia with small electrodes: a double-blind, randomized, feasibility study protocol
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    Frontiers in Neurology.2026;[Epub]     CrossRef
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    Arzucan Toksal Uçar, Bilge Piri Çınar, Banu Alıcıoğlu, Geylan Bostan, Sevil Bilgin
    Journal of Oral Rehabilitation.2025; 52(3): 320.     CrossRef
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    Trịnh Minh Trí Trịnh Minh Trí , Văn Hồng Phượng Văn Hồng Phượng, Phạm Nguyên Quân Phạm Nguyên Quân
    Tạp Chí Khoa học Trường Đại học Quốc tế Hồng Bàng.2025; : 35.     CrossRef
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    Journal of Oral Rehabilitation.2025; 52(6): 817.     CrossRef
  • Swallowing Therapy Effects on Oral Muscle Mass, Tongue Function, Swallowing, and Nutrition in Stroke Patients with Dysphagia
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    NeuroRehabilitation: An International, Interdisciplinary Journal.2025; 56(2): 164.     CrossRef
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    Mila Bunijevac
    Srpski arhiv za celokupno lekarstvo.2025; 153(1-2): 78.     CrossRef
  • Dysphagia Prevention Strategies for Community‐Dwelling Older Adults: A Scoping Review
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    Journal of Oral Rehabilitation.2025; 52(5): 722.     CrossRef
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    Journal of Speech, Language, and Hearing Research.2025; 68(05): 2318.     CrossRef
  • A tongue resistance training program improves strength, endurance, and swallowing in frail older adults with mild cognitive impairment: a double-blind randomized controlled trial
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    GeroScience.2025;[Epub]     CrossRef
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    Amna S. Mira, Anna K. Hopkins, Meredith E. Tabangin, Mekibib Altaye, Brittany N. Krekeler
    American Journal of Speech-Language Pathology.2025; 34(4): 2072.     CrossRef
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    Yung-Sheng Huang, Hen-Hong Chang, John Y. Chiang, Po-Chi Hsu, Lun-Chien Lo
    Frontiers in Neurology.2025;[Epub]     CrossRef
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    Journal of Oral Rehabilitation.2024; 51(11): 2270.     CrossRef
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    Jiahua lyu, Yue Su, Hansong Bai, Hao Kuang, Churong Li, Xiumei Zheng, Long Liang, Lu li, Diou Cheng, Tao Li
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  • Application of Ultrasonography in Neurogenic Dysphagia: A Systematic Review
    Paola Potente, Alex Buoite Stella, Monica Vidotto, Michelle Passerini, Giovanni Furlanis, Marcello Naccarato, Paolo Manganotti
    Dysphagia.2023; 38(1): 65.     CrossRef
  • Perioperative Decrease in Tongue Pressure is an Intervenable Predictor of Aspiration After Esophagectomy
    Kazuhiro Kojima, Takuya Fukushima, Daisuke Kurita, Aiko Matsuoka, Koshiro Ishiyama, Junya Oguma, Hiroyuki Daiko
    Dysphagia.2023; 38(4): 1147.     CrossRef
  • Maximum lingual pressure impacts both swallowing safety and efficiency in individuals with amyotrophic lateral sclerosis
    Raele Donetha Robison, Lauren DiBiase, Amber Anderson, James P. Wymer, Emily K. Plowman
    Neurogastroenterology & Motility.2023;[Epub]     CrossRef
  • Effects of Device-Facilitated Lingual Strengthening Therapy on Dysphagia Related Outcomes in Patients Post-Stroke: A Randomized Controlled Trial
    Brittany N. Krekeler, Joanne Yee, Atsuko Kurosu, Fauzia Osman, Rodolfo Peña-Chávez, Glen Leverson, Brittany Young, Justin Sattin, Molly Knigge, Susan Thibeault, Nicole Rogus-Pulia
    Dysphagia.2023; 38(6): 1551.     CrossRef
  • Evaluation of usefulness of tongue pressure measurement device for dysphagia associated with treatment of patients with head and neck cancer (ELEVATE)
    Akihisa Tanaka, Hirokazu Uemura, Takahiro Kimura, Ari Nishimura, Kumiko Aoki, Shintaro Otsuka, Keita Ueda, Tadashi Kitahara
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