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"Tayeun Kim"

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"Tayeun Kim"

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Brain disorders

Changes in Function and Muscle Strength of Encephalitis Survivors After Inpatient Rehabilitation
Tayeun Kim, In Yae Cheong
Ann Rehabil Med 2021;45(6):422-430.   Published online December 31, 2021
DOI: https://doi.org/10.5535/arm.21133
Objective
To investigate the clinical demographics and rehabilitative assessments of encephalitis survivors admitted to a rehabilitation center, and to confirm the effects of inpatient rehabilitation manifested by changes in muscle strength and function after hospitalization.
Methods
Data of encephalitis survivors who received rehabilitation at our institution from August 2009 to August 2019 were reviewed. Medical charts were retrospectively reviewed, and motor, functional, and cognitive assessments were collected. Manual muscle testing (MMT), Fugl-Meyer Assessment (FMA), Berg Balance Scale (BBS), Functional Ambulation Category (FAC), Korean version of Modified Barthel Index (K-MBI), grip strength, Box and Block Test (BBT), and Korean version of Mini-Mental State Examination (K-MMSE) were performed, and the results upon admission and discharge were compared and analyzed.
Results
Most of the patients with encephalitis admitted to our institution had viral or autoimmune etiologies. The assessment results of 18 encephalitis patients upon admission and discharge were compared. The total K-MBI score, FAC, grip strength, and BBT significantly improved, but not the MMT and FMA. Subgroup analysis was performed for viral and autoimmune encephalitis, which are the main causes of the disease, but there was no difference in items with significant changes before and after hospitalization.
Conclusion
Encephalitis survivors showed a significant improvement in functional assessment scale during their hospital stay through rehabilitation, without significant changes in motor strength. Hence, we can conclude that encephalitis survivors benefit from inpatient rehabilitation, targeting functional gains in activities of daily living training more than motor strength.

Citations

Citations to this article as recorded by  
  • Activated Microglia Mediate the Motor Neuron‐, Synaptic Denervation‐ and Muscle Wasting‐Changes in Burn Injured Mice
    Jingyuan Chen, Yoshinori Kitagawa, Fei Xie, Haobo Li, William R. Kem, Zerong You, Shingo Yasuhara, J. A. Jeevendra Martyn
    Journal of Cachexia, Sarcopenia and Muscle.2025;[Epub]     CrossRef
  • Handgrip strength and upper limb functional performance measures in people over 18 years old: Analysis of relationships and influencing factors
    Julio Ernesto Pérez-Parra, Claudia Patricia Henao-Lema, Anyi Vanesa Arcos-Rodríguez, Natalia López-Ocampo, Carolina Castaño-García, Olga Patricia Pérez-Gamboa
    Journal of Hand Therapy.2024; 37(1): 101.     CrossRef
  • Outcome and Sequelae of Autoimmune Encephalitis
    Kathryn A. Kvam, Jean-Paul Stahl, Felicia C. Chow, Ariane Soldatos, Pierre Tattevin, James Sejvar, Alexandra Mailles
    Journal of Clinical Neurology.2024; 20(1): 3.     CrossRef
  • Effect of Timing of Rehabilitation Nursing Intervention on Children with Acute Viral Encephalitis
    Haiyan Zhang, Shuangying Huang, Biyun He, Lingming Shen, Xiaoqing Li, Chen Shen, Bo Chen
    Iranian Journal of Pediatrics.2024;[Epub]     CrossRef
  • State of the Art: Acute Encephalitis
    Karen C Bloch, Carol Glaser, David Gaston, Arun Venkatesan
    Clinical Infectious Diseases.2023; 77(5): e14.     CrossRef
  • 5,911 View
  • 126 Download
  • 5 Web of Science
  • 5 Crossref
Prevalence and Characteristics of Neuropathic Pain in Patients With Spinal Cord Injury Referred to a Rehabilitation Center
Hae Young Kim, Hye Jin Lee, Tae-lim Kim, EunYoung Kim, Daehoon Ham, Jaejoon Lee, Tayeun Kim, Ji Won Shin, Minkyoung Son, Jun Hun Sung, Zee-A Han
Ann Rehabil Med 2020;44(6):438-449.   Published online December 31, 2020
DOI: https://doi.org/10.5535/arm.20081
Objective
To identify the prevalence and characteristics of neuropathic pain (NP) in patients with spinal cord injury (SCI) and to investigate associations between NP and demographic or disease-related variables.
Methods
We retrospectively reviewed medical records of patients with SCI whose pain was classified according to the International Spinal Cord Injury Pain classifications at a single hospital. Multiple statistical analyses were employed. Patients aged <19 years, and patients with other neurological disorders and congenital conditions were excluded.
Results
Of 366 patients, 253 patients (69.1%) with SCI had NP. Patients who were married or had traumatic injury or depressive mood had a higher prevalence rate. When other variables were controlled, marital status and depressive mood were found to be predictors of NP. There was no association between the prevalence of NP and other demographic or clinical variables. The mean Numeric Rating Scale (NRS) of NP was 4.52, and patients mainly described pain as tingling, squeezing, and painful cold. Females and those with below-level NP reported more intense pain. An NRS cut-off value of 4.5 was determined as the most appropriate value to discriminate between patients taking pain medication and those who did not.
Conclusion
In total, 69.1% of patients with SCI complained of NP, indicating that NP was a major complication. Treatment planning for patients with SCI and NP should consider that marital status, mood, sex, and pain subtype may affect NP, which should be actively managed in patients with an NRS ≥4.5.

Citations

Citations to this article as recorded by  
  • Mechanisms and Therapeutic Prospects of Microglia-Astrocyte Interactions in Neuropathic Pain Following Spinal Cord Injury
    Yinuo Liu, Xintong Cai, Bowen Shi, Yajie Mo, Jianmin Zhang, Wenting Luo, Bodong Yu, Xi Li
    Molecular Neurobiology.2025; 62(4): 4654.     CrossRef
  • Comparative outcomes of microsurgical dorsal root entry zone lesioning (DREZotomy) for intractable neuropathic pain in spinal cord and cauda equina injuries
    Bunpot Sitthinamsuwan, Tanawat Ounahachok, Sawanee Pumseenil, Sarun Nunta-aree
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Efficacy of neuromodulation and rehabilitation approaches on pain relief in patients with spinal cord injury: a systematic review and meta-analysis
    Simona Portaro, Angelo Alito, Giulia Leonardi, Nicola Marotta, Adriana Tisano, Daniele Bruschetta, Umile Giuseppe Longo, Antonio Ammendolia, Demetrio Milardi, Alessandro de Sire
    Neurological Sciences.2025;[Epub]     CrossRef
  • Correlation of Severity of Neuropathic Pain in Traumatic Spinal Cord Injury Patients with Sociodemographic and Clinical Characteristics Including Depression and Quality of Life: A Cross-sectional Study
    Arun Yadav, Mrinal Joshi, Shivangi Yadav
    Indian Journal of Physical Medicine and Rehabilitation.2025; 35(2): 128.     CrossRef
  • Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels
    Maryam Hadadi, Mohammad Mojtaba Farazi, Mehrnaz Mehrabani, Mahsa Tashakori-Miyanroudi, Zahra Behroozi
    Scientific Reports.2025;[Epub]     CrossRef
  • Clinical Characteristics of Adults Living with a Spinal Cord Injury Across the Continuum of Care: A Population-Based Cross-Sectional Study
    Matteo Ponzano, Anja Declercq, Melissa Ziraldo, John P. Hirdes
    Journal of Clinical Medicine.2025; 14(9): 3060.     CrossRef
  • Occurrence of neuropathic pain and its characteristics in patients with traumatic spinal cord injury
    Arun Yadav, Mrinal Joshi
    The Journal of Spinal Cord Medicine.2024; 47(6): 952.     CrossRef
  • Post-discharge follow-up of patients with spine trauma in the National Spinal Cord Injury Registry of Iran during the COVID-19 pandemic: Challenges and lessons learned
    Zahra Azadmanjir, Moein Khormali, Mohsen Sadeghi-Naini, Vali Baigi, Habibollah Pirnejad, Mohammad Dashtkoohi, Zahra Ghodsi, Seyed Behnam Jazayeri, Aidin Shakeri, Mahdi Mohammadzadeh, Laleh Bagheri, Mohammad-Sajjad Lotfi, Salman Daliri, Amir Azarhomayoun,
    Chinese Journal of Traumatology.2024; 27(3): 173.     CrossRef
  • Randomised, double-blind, placebo-controlled, parallel-group, multicentric, phase IIA clinical trial for evaluating the safety, tolerability, and therapeutic efficacy of daily oral administration of NFX88 to treat neuropathic pain in individuals with spin
    Pablo V. Escribá, Ángel M. Gil-Agudo, Joan Vidal Samsó, Judith Sánchez-Raya, Sebastián Salvador-de la Barrera, Vanesa Soto-León, Natacha León-Álvarez, Bosco Méndez Ferrer, Miguel David Membrilla-Mesa, Carolina Redondo Galán, Jesús Benito-Penalva, Antonio
    Spinal Cord.2024; 62(8): 454.     CrossRef
  • Low back pain classifications and their associations with disability, quality-of-life, and sociodemographic factors: a comprehensive examination using the PainDETECT questionnaire
    Zachary Gan, Stone Sima, Samuel Lapkin, Ashish D. Diwan
    Current Medical Research and Opinion.2024; 40(8): 1379.     CrossRef
  • Research progress in neuropathic pain after spinal cord injury: a bibliometric study from 2013 to 2024
    Qin Huiqing, Lin Weishan, Gui Yuchang, Tang Yun, Xu Jianwen
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Prevalence and Determinants of Pain in Spinal Cord Injury During Initial Inpatient Rehabilitation: Data From the Dutch Spinal Cord Injury Database
    Tim C. Crul, Marcel W.M. Post, Johanna M.A. Visser-Meily, Janneke M. Stolwijk-Swüste
    Archives of Physical Medicine and Rehabilitation.2023; 104(1): 74.     CrossRef
  • Ectopic expression of Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model
    Yan Fu, Liting Sun, Fengting Zhu, Wei Xia, Ting Wen, Ruilong Xia, Xin Yu, Dan Xu, Changgeng Peng
    Frontiers in Molecular Neuroscience.2023;[Epub]     CrossRef
  • Precision neuromodulation: Promises and challenges of spinal stimulation for multi-modal rehabilitation
    Maria F. Bandres, Jefferson L. Gomes, Gerson N. Moreno Romero, Avery R. Twyman, Jacob Graves McPherson
    Frontiers in Rehabilitation Sciences.2023;[Epub]     CrossRef
  • A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury
    Mu-Lan Xu, Xiang-Bo Wu, Ying Liang, Ning Li, Xu Hu, Xiao-Dong Lin, Miao-Qiao Sun, Chun-Qiu Dai, Dan Niu, Yan-Rong Zhang, Hui Cao, Chen-Guang Zhao, Xiao-Long Sun, Hua Yuan
    Journal of Pain Research.2023; Volume 16: 2619.     CrossRef
  • Feasibility of using remotely delivered Spring Forest Qigong to reduce neuropathic pain in adults with spinal cord injury: a pilot study
    Ann Van de Winckel, Sydney T. Carpentier, Wei Deng, Lin Zhang, Angela Philippus, Ricardo Battaglino, Leslie R. Morse
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • An Exploratory EEG Analysis on the Effects of Virtual Reality in People with Neuropathic Pain Following Spinal Cord Injury
    Yvonne Tran, Philip Austin, Charles Lo, Ashley Craig, James W. Middleton, Paul J. Wrigley, Philip Siddall
    Sensors.2022; 22(7): 2629.     CrossRef
  • Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury
    Zefu Li, Huiying Bai, Ruoyu Zhang, Bohan Chen, Junmin Wang, Bohan Xue, Xiuhua Ren, Jiarui Wang, Yanjie Jia, Weidong Zang, Jian Wang, Xuemei Chen
    European Journal of Neuroscience.2022; 56(2): 3991.     CrossRef
  • Phenotypes of Motor Deficit and Pain after Experimental Spinal Cord Injury
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  • Peripheral Immune Dysfunction: A Problem of Central Importance after Spinal Cord Injury
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    Biology.2021; 10(9): 928.     CrossRef
  • 5,799 View
  • 186 Download
  • 22 Web of Science
  • 20 Crossref
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