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"Kwang Jae Lee"

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"Kwang Jae Lee"

Original Articles

Brain disorders

Efficacy and Safety of Botulinum Toxin Type A (NABOTA) for Post-stroke Upper Extremity Spasticity: A Multicenter Phase IV Trial
Wonjae Hwang, Seong Min Kang, Sang Yoon Lee, Han Gil Seo, Yoon Ghil Park, Bum Sun Kwon, Kwang Jae Lee, Deog Young Kim, Hyoung Seop Kim, Shi-Uk Lee
Ann Rehabil Med 2022;46(4):163-171.   Published online August 31, 2022
DOI: https://doi.org/10.5535/arm.22061
Objective
To evaluate the efficacy and safety of Daewoong botulinum toxin type A (NABOTA) after its launch in South Korea.
Methods
This prospective, multicenter, open-label phase IV clinical trial included 222 patients with stroke. All patients visited the clinic at baseline and at weeks 4, 8, and 12 after injection of upto 360 units of NABOTA into the wrist, elbow, and finger flexor muscles at the first visit. The primary outcome was the change in Modified Ashworth Scale (MAS) score for the wrist flexor muscles between baseline and week 4. The secondary outcomes were the changes in MAS, Disability Assessment Scale (DAS), and Caregiver Burden Scale (CBS) scores between baseline and each visit, and the Global Assessment Scale (GAS) score at week 12.
Results
There was a statistically significant decrease in the MAS score for the wrist flexors between baseline and week 4 (-0.97±0.66, p<0.001). Compared with baseline, the MAS, DAS and CBS scores improved significantly during the study period. The GAS was rated as very good or good by 86.8% of physicians and by 60.0% of patients (or caregivers). The incidence of adverse events was 14.4%, which is smaller than that in a previous trial.
Conclusion
NABOTA showed considerable efficacy and safety in the management of upper limb spasticity in stroke patients.
  • 6,318 View
  • 159 Download
Transabdominal Functional Magnetic Stimulation for the Treatment of Constipation in Brain-Injured Patients: A Randomized Controlled Trial
Young-Cheol Yun, Yong-Soon Yoon, Eun-Sil Kim, Young-Jae Lee, Jin-Gyeong Lee, Won-Jae Jo, Kwang Jae Lee
Ann Rehabil Med 2019;43(1):19-26.   Published online February 28, 2019
DOI: https://doi.org/10.5535/arm.2019.43.1.19
Objective
To investigate the effects of the transabdominal functional magnetic stimulation (A-FMS) for constipation in stroke or brain-injured patients.
Methods
Twenty-four brain-injured patients (11 males and 13 females; median age, 65 years; 22 cases of stroke and 2 cases of traumatic brain injury) with constipation, who were admitted to the rehabilitation department, were enrolled and randomly divided into magnetic stimulation (MS) group and sham stimulation (Sham) group. Several parameters related with constipation such as total and segmental colon transit time (CTT), defecation frequency, and Bristol Stool Scale (BSS) before and after 2 weeks of A-FMS (5 times per week, total 10 times of A-FMS) were evaluated. The Korean version of the Modified Barthel Index (K-MBI) was also evaluated.
Results
A significant decrease in segmental CTT in the left colon (-8.2±3.9 vs. 4.1±2.5 hours; p<0.05 by paired sample t-test) and a significant increase in the frequency of defecation (1.5±0.2 vs 0.7±0.3; p<0.05 by paired sample t-test) were observed in the MS group compared with the Sham group. Stool hardness became significantly softer in the MS group compared with the Sham group (2.3–3.5 in the MS and 2.6–3.1 in the Sham; p<0.05 by chi-square test) as evaluated by BSS. No difference in the K-MBI was observed between the two groups.
Conclusion
The present study suggests that A-FMS can be an additional therapeutic tool for managing constipation in brain-injured patients with abnormal bowel movement, defecation frequency, and stool hardness.

Citations

Citations to this article as recorded by  
  • The Effect of Magnetic Therapy on Postoperative Urinary Retention in Patients Undergoing Surgery: A Randomized Clinical Trial
    Ghasem Zarei, Sorour Mosleh, Soraya Zare, Mohammad Sadegh Abotalebi
    Iranian Journal of Nursing and Midwifery Research.2024; 29(4): 417.     CrossRef
  • Conservative, physical and surgical interventions for managing faecal incontinence and constipation in adults with central neurological diseases
    Claire L Todd, Eugenie E Johnson, Fiona Stewart, Sheila A Wallace, Andrew Bryant, Sue Woodward, Christine Norton
    Cochrane Database of Systematic Reviews.2024;[Epub]     CrossRef
  • High-Frequency Repetitive Magnetic Stimulation at the Sacrum Alleviates Chronic Constipation in Parkinson’s Patients
    Mei Huang, Bofang Zheng, Wanfei Zhou, Huaili Fu, Xinrun Chen, Heyong Wu, Jianguo Zhang, Xianju Zhou
    Annals of Indian Academy of Neurology.2023; 26(3): 235.     CrossRef
  • Bowel dysfunctions after acquired brain injury: a scoping review
    Matteo Zandalasini, Laura Pelizzari, Gianluca Ciardi, Donatella Giraudo, Massimo Guasconi, Stefano Paravati, Gianfranco Lamberti, Antonio Frizziero
    Frontiers in Human Neuroscience.2023;[Epub]     CrossRef
  • The effect of the therapy of “combination 3 methods progression” in patients with neurogenic bowel dysfunction (constipated type)
    Qing Li, Yin-Li Shen, Yun-Lan Jiang, Dong-Shuang Li, Song Jin
    Medicine.2021; 100(7): e24662.     CrossRef
  • Efficacy of functional magnetic stimulation in improving upper extremity function after stroke: a randomized, single-blind, controlled study
    Xiaowei Chen, Xuncan Liu, Yinxing Cui, Guoxing Xu, Lu Liu, Xueru Zhang, Kun Jiang, Zhenlan Li
    Journal of International Medical Research.2020;[Epub]     CrossRef
  • Dose–response of rPMS for upper Limb hemiparesis after stroke
    Shoji Kinoshita, Kumi Ikeda, Shinji Yasuno, Sho Takahashi, Naoki Yamada, Yumi Okuyama, Nobuyuki Sasaki, Takuya Hada, Chiaki Kuriyama, Shin Suzuki, Midori Hama, Naoto Ozaki, Shu Watanabe, Masahiro Abo
    Medicine.2020; 99(24): e20752.     CrossRef
  • 7,922 View
  • 163 Download
  • 7 Web of Science
  • 7 Crossref
A New Instrument for Measuring Tibial Torsion in Pediatric Patients
Ji Hyun Jeon, Yong-Soon Yoon, Kwang Jae Lee, Ki Pi Yu, Jong Hoo Lee, Tae Yong Seog, EunJi Son
Ann Rehabil Med 2017;41(3):441-449.   Published online June 29, 2017
DOI: https://doi.org/10.5535/arm.2017.41.3.441
Objective

To develop and test the validity and reliability of a new instrument for measuring the thigh-foot angle (TFA) for the patients with in-toeing and out-toeing gait.

Methods

The new instrument (Thigh-Foot Supporter [TFS]) was developed by measuring the TFA during regular examination of the tibial torsional status. The study included 40 children who presented with in-toeing and out-toeing gaits. We took a picture of each case to measure photographic-TFA (P-TFA) in the proper position and to establish a criterion. Study participants were examined by three independent physicians (A, B, and C) who had one, three and ten years of experience in the field, respectively. Each examiner conducted a separate classical physical examination (CPE) of every participant using a gait goniometer followed by a TFA assessment of each pediatric patient with or without the TFS. Thirty minutes later, repeated in the same way was measured.

Results

Less experienced examiner A showed significant differences between the TFA values depending on whether TFS used (left p=0.003 and right p=0.008). However, experienced examiners B and C did not show significant differences. Using TFS, less experienced examiner A showed a high validity and all examiner's inter-test and the inter-personal reliabilities increased.

Conclusion

TFS may increase validity and reliability in measuring tibial torsion in patients who has a rotational problem in lower extremities. It would be more useful in less experienced examiners.

Citations

Citations to this article as recorded by  
  • Rotational anomalies in patients with hallux valgus .Observational Study
    Rosana Giménez López
    Revista Española de Podología.2023;[Epub]     CrossRef
  • Comparison of multiple flatfoot indicators in 5–8-year-old children
    Saidas Žukauskas, Vidmantas Barauskas, Emilis Čekanauskas
    Open Medicine.2021; 16(1): 246.     CrossRef
  • 6,415 View
  • 116 Download
  • 2 Web of Science
  • 2 Crossref
Effect of Epidural Electrical Stimulation and Repetitive Transcranial Magnetic Stimulation in Rats With Diffuse Traumatic Brain Injury
Yong-Soon Yoon, Kang Hee Cho, Eun-Sil Kim, Mi-Sook Lee, Kwang Jae Lee
Ann Rehabil Med 2015;39(3):416-424.   Published online June 30, 2015
DOI: https://doi.org/10.5535/arm.2015.39.3.416
Objective

To evaluate the effects of epidural electrical stimulation (EES) and repetitive transcranial magnetic stimulation (rTMS) on motor recovery and brain activity in a rat model of diffuse traumatic brain injury (TBI) compared to the control group.

Methods

Thirty rats weighing 270-285 g with diffuse TBI with 45 kg/cm2 using a weight-drop model were assigned to one of three groups: the EES group (ES) (anodal electrical stimulation at 50 Hz), the rTMS group (MS) (magnetic stimulation at 10 Hz, 3-second stimulation with 6-second intervals, 4,000 total stimulations per day), and the sham-treated control group (sham) (no stimulation). They were pre-trained to perform a single-pellet reaching task (SPRT) and a rotarod test (RRT) for 14 days. Diffuse TBI was then induced and an electrode was implanted over the dominant motor cortex. The changes in SPRT success rate, RRT performance time rate and the expression of c-Fos after two weeks of EES or rTMS were tracked.

Results

SPRT improved significantly from day 8 to day 12 in the ES group and from day 4 to day 14 in the MS group (p<0.05) compared to the sham group. RRT improved significantly from day 6 to day 11 in ES and from day 4 to day 9 in MS compared to the sham group. The ES and MS groups showed increased expression of c-Fos in the cerebral cortex compared to the sham group.

Conclusion

ES or MS in a rat model of diffuse TBI can be used to enhance motor recovery and brain activity.

Citations

Citations to this article as recorded by  
  • Neurophysiological Markers of Reward Processing Can Inform Preclinical Neurorehabilitation Approaches for Cognitive Impairments Following Brain Injury
    Miranda Francoeur Koloski, Reyana Menon, Victoria Krasnyanskiy
    Brain Sciences.2025; 15(5): 471.     CrossRef
  • Neuromodulation techniques in traumatic brain injury: a narrative review of the current state
    Mrinmoy Kundu, Vallabh Shet, Tariq Janjua, Luis Rafael Moscote
    Acta Neurologica Belgica.2024;[Epub]     CrossRef
  • Repetitive transcranial magnetic stimulation promotes neurological functional recovery in rats with traumatic brain injury by upregulating synaptic plasticity-related proteins
    Fang-Fang Qian, You-Hua He, Xiao-Hui Du, Hua-Xiang Lu, Ren-Hong He, Jian-Zhong Fan
    Neural Regeneration Research.2023; 18(2): 368.     CrossRef
  • Neuromodulation Therapies in Pre-Clinical Models of Traumatic Brain Injury: Systematic Review and Translational Applications
    Shanan Surendrakumar, Thallita Kelly Rabelo, Ana Carolina P. Campos, Adriano Mollica, Agessandro Abrahao, Nir Lipsman, Matthew J. Burke, Clement Hamani
    Journal of Neurotrauma.2023; 40(5-6): 435.     CrossRef
  • Electrical stimulation methods and protocols for the treatment of traumatic brain injury: a critical review of preclinical research
    D. Ziesel, M. Nowakowska, S. Scheruebel, K. Kornmueller, U. Schäfer, R. Schindl, C. Baumgartner, M. Üçal, T. Rienmüller
    Journal of NeuroEngineering and Rehabilitation.2023;[Epub]     CrossRef
  • The Rehabilitation Potential of Neurostimulation for Mild Traumatic Brain Injury in Animal and Human Studies
    M. Windy McNerney, Gene G. Gurkoff, Charlotte Beard, Marian E. Berryhill
    Brain Sciences.2023; 13(10): 1402.     CrossRef
  • Repetitive transcranial magnetic stimulation in traumatic brain injury: Evidence from animal and human studies
    Raffaele Nardone, Luca Sebastianelli, Viviana Versace, Francesco Brigo, Stefan Golaszewski, Paolo Manganotti, Leopold Saltuari, Eugen Trinka
    Brain Research Bulletin.2020; 159: 44.     CrossRef
  • Transcranial magnetic stimulation in the correction of consequences of minor traumatic brain injury
    I. V. Litvinenko, A. A. Yurin
    Marine Medicine.2020; 6(2): 36.     CrossRef
  • Motor cortex stimulation does not lead to functional recovery after experimental cortical injury in rats
    Lisa-Maria Schönfeld, Ali Jahanshahi, Evi Lemmens, Matthias Bauwens, Sarah-Anna Hescham, Sandra Schipper, Melanie Lagiere, Sven Hendrix, Yasin Temel
    Restorative Neurology and Neuroscience.2017; 35(3): 295.     CrossRef
  • Effect of Intermediate-Frequency Repetitive Transcranial Magnetic Stimulation on Recovery following Traumatic Brain Injury in Rats
    Leticia Verdugo-Diaz, Francisco Estrada-Rojo, Aron Garcia-Espinoza, Eduardo Hernandez-Lopez, Alejandro Hernandez-Chavez, Carlos Guzman-Uribe, Marina Martinez-Vargas, Adan Perez-Arredondo, Tomas Calvario, David Elias-Viñas, Luz Navarro
    BioMed Research International.2017; 2017: 1.     CrossRef
  • MAGNETIC STIMULATION IN DIAGNOSIS AND TREATMENT OF DISEASES AND INJURIES OF THE NERVOUS SYSTEM
    Igor V Litvinenko, Anton A Yurin, Daria N Frunza, Tatyana V Bodrova
    Bulletin of the Russian Military Medical Academy.2017; 19(3): 49.     CrossRef
  • Vagus Nerve Stimulation and Other Neuromodulation Methods for Treatment of Traumatic Brain Injury
    Daniel Neren, Matthew D. Johnson, Wynn Legon, Salam P. Bachour, Geoffrey Ling, Afshin A. Divani
    Neurocritical Care.2016; 24(2): 308.     CrossRef
  • 6,091 View
  • 73 Download
  • 9 Web of Science
  • 12 Crossref

Case Report

Balloon Dilatation for an Esophageal Stricture by Long-Term Use of a Nasogastric Tube: A Case Report
Yong-Soon Yoon, Jong Yun Kim, Kwang Jae Lee, Ki Pi Yu, Mi Sook Lee
Ann Rehabil Med 2014;38(4):581-584.   Published online August 28, 2014
DOI: https://doi.org/10.5535/arm.2014.38.4.581

In the present report, we describe a case of long-term follow-up esophageal stricture occurring in a patient with nasogastric tube use. A 63-year-old man who had experienced dislocation of the 6th and 7th cervical vertebrae as the result of an external injury received treatment at another hospital and was admitted to the rehabilitation department of our hospital. After he exhibited normal swallowing in a videofluoroscopic swallowing test, the nasogastric tube was removed and oral feeding with a dysphagia diet was initiated. However, during oral feeding, the patient complained of swallowing difficulties in his lower throat. An esophagogastroduodenoscopy was performed to examine the lesions below the pharynx and a 2-mm stricture was observed. A balloon dilatation was performed for a total of 9 times to extend the stricture. After the procedure, the patient was able to easily swallow a normal diet through the esophagus and the vomiting symptoms disappeared. An esophagography showed that the diameter of the esophageal stricture was 11 mm.

  • 4,204 View
  • 33 Download
  • 1 Web of Science
Original Article
Development and Application of a Newly Designed Massage Instrument for Deep Cross-Friction Massage in Chronic Non-Specific Low Back Pain
Yong-Soon Yoon, Ki-Pi Yu, Kwang Jae Lee, Soo-Hyun Kwak, Jong Yun Kim
Ann Rehabil Med 2012;36(1):55-65.   Published online February 29, 2012
DOI: https://doi.org/10.5535/arm.2012.36.1.55
Objective

To introduce a newly designed massage instrument, the Hand Grip T-bar (HT-bar) and use it to relieve chronic non-specific low back pain (nLBP) through deep cross-friction massage (roptrotherapy).

Method

22 subjects (9 males and 13 females, aged 51.6±6.7) with chronic nLBP were allocated randomly to a Roptrotherapy group (n=12) and a Transcutaneous Electrical Nerve Stimulation (TENS) group (n=10). The Roptrotherapy group received deep cross-friction massage with the HT-bar, which was made of metal and had a cylinder for increasing weight and grooves for an easy grip. It was applied across the middle and lower back for 20 minutes a day, 3 days a week for 2 weeks. The TENS group received TENS for 20 minutes a day, 5 days a week for 2 weeks. The outcome was measured on the pain numeric rating scale (PNRS), by the Oswestry disability index (ODI), and by the Roland & Morris Disability Questionnaire (RMDQ) at pre-treatment, at immediate post-treatment and 2 weeks later. The application of the HT-bar was assessed by a questionnaire to 19 therapists.

Results

At post-treatment, immediately and 2 weeks later, both groups showed significant improvement in PNRS, ODI and RMDQ. During the two weeks after post-treatment, however, the Roptrotherapy group improved in PNRS, ODI and RMDQ, but the TENS group did not. Over 80% of the therapists responded that the HT-bar was useful and comfortable.

Conclusion

This study suggests that deep cross-friction massage can be a beneficial therapeutic technique and that the HT-bar can be a useful instrument in deep cross-friction massage for chronic nLBP patients.

Citations

Citations to this article as recorded by  
  • Physiotherapeutic and non-conventional approaches in patients with chronic low-back pain: a level I Bayesian network meta-analysis
    Alice Baroncini, Nicola Maffulli, Luise Schäfer, Nicola Manocchio, Michela Bossa, Calogero Foti, Alexandra Klimuch, Filippo Migliorini
    Scientific Reports.2024;[Epub]     CrossRef
  • Clinical Impact of Thermotherapy and Spinal Twisting Massage on Chronic Non-Specific Spinal Pain
    Syung Hyun Cho, Un Mo Jeong, Sung Hoon Kim
    Medicina.2024; 60(6): 976.     CrossRef
  • Prognostic Factors in Patients Undergoing Physiotherapy for Chronic Low Back Pain: A Level I Systematic Review
    Alice Baroncini, Nicola Maffulli, Marco Pilone, Gennaro Pipino, Michael Kurt Memminger, Gaetano Pappalardo, Filippo Migliorini
    Journal of Clinical Medicine.2024; 13(22): 6864.     CrossRef
  • Bibliometric Analysis of Research Trends on Manual Therapy for Low Back Pain Over Past 2 Decades
    Lele Huang, Jiamin Li, Baiyang Xiao, Yin Tang, Jinghui Huang, Ying Li, Fanfu Fang
    Journal of Pain Research.2023; Volume 16: 3045.     CrossRef
  • The Effect of Massage Force on Relieving Nonspecific Low Back Pain: A Randomized Controlled Trial
    Pei-Chun Chen, Li Wei, Chung-Yu Huang, Feng-Hang Chang, Yen-Nung Lin
    International Journal of Environmental Research and Public Health.2022; 19(20): 13191.     CrossRef
  • ACUTE EFFECTS OF INTRAMUSCULAR STRETCHING AND PASSIVE STRETCHING ON SPASTICITY IN CHILDREN WITH CEREBRAL PALSY
    Kamile UZUN AKKAYA, Bülent ELBASAN
    Türk Fizyoterapi ve Rehabilitasyon Dergisi.2021; 32(1): 60.     CrossRef
  • Randomized Trial of Modified Stretching Exercise Program for Menstrual Low Back Pain
    Huei-Mein Chen, Hsou-Mei Hu
    Western Journal of Nursing Research.2019; 41(2): 238.     CrossRef
  • Abstracts of Low Back Pain Trials Are Poorly Reported, Contain Spin of Information, and Are Inconsistent With the Full Text: An Overview Study
    Dafne P. Nascimento, Leonardo O.P. Costa, Gabrielle Z. Gonzalez, Christopher G. Maher, Anne M. Moseley
    Archives of Physical Medicine and Rehabilitation.2019; 100(10): 1976.     CrossRef
  • Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain: A Clinical Practice Guideline From the American College of Physicians
    Amir Qaseem, Timothy J. Wilt, Robert M. McLean, Mary Ann Forciea
    Annals of Internal Medicine.2017; 166(7): 514.     CrossRef
  • Nonpharmacologic Therapies for Low Back Pain: A Systematic Review for an American College of Physicians Clinical Practice Guideline
    Roger Chou, Richard Deyo, Janna Friedly, Andrea Skelly, Robin Hashimoto, Melissa Weimer, Rochelle Fu, Tracy Dana, Paul Kraegel, Jessica Griffin, Sara Grusing, Erika D. Brodt
    Annals of Internal Medicine.2017; 166(7): 493.     CrossRef
  • The neuromotor effects of transverse friction massage
    Haris Begovic, Guang-Quan Zhou, Snježana Schuster, Yong-Ping Zheng
    Manual Therapy.2016; 26: 70.     CrossRef
  • Massage for low-back pain
    Andrea D Furlan, Mario Giraldo, Amanda Baskwill, Emma Irvin, Marta Imamura
    Cochrane Database of Systematic Reviews.2015;[Epub]     CrossRef
  • Effectiveness of a Stretching Exercise Program on Low Back Pain and Exercise Self-Efficacy Among Nurses in Taiwan: A Randomized Clinical Trial
    Huei-Mein Chen, Hsiu-Hung Wang, Chung-Hey Chen, Hsou-Mei Hu
    Pain Management Nursing.2014; 15(1): 283.     CrossRef
  • 6,335 View
  • 78 Download
  • 13 Crossref
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