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"Hye Jin Lee"

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Spinal cord injury

Should We Delay Urodynamic Study When Patients With Spinal Cord Injury Have Asymptomatic Pyuria?
EunYoung Kim, Hye Jin Lee, Onyoo Kim, In Suk Park, Bum-Suk Lee
Ann Rehabil Med 2021;45(3):178-185.   Published online June 14, 2021
DOI: https://doi.org/10.5535/arm.20241
Objective
To assess the incidence of urinary tract infection (UTI) with post-urodynamic study (post-UDS) in patients with spinal cord injury (SCI) and study its relationship with pre-UDS pyuria.
Methods
Patients with SCI who were hospitalized and underwent UDS during a 4-year period were reviewed. Patients with pre-test lower urinary tract symptoms were excluded. Urinalysis and urine culture were performed before and 24 hours after UDS. Prophylactic antibiotics were administered for 5 days starting from the morning of the UDS. UTI was defined as bacteriuria with accompanying symptoms.
Results
Of 399 patients reviewed, 209 (52.4%) had pyuria in pre-UDS urinalysis, and 257 (64.4%) had bacteriuria in pre-UDS culture. Post-UDS UTI occurred in 6 (1.5%) individuals who all complained of fever: 5 (2.4%) of the post-UDS UTI cases occurred in patients with pre-UDS pyuria, and 1 (0.5%) in a person without. The differences between groups were not statistically significant (p=0.218). Of 221 patients with bacteriuria (gram-negative isolates) on pre-UDS culture, resistance to ciprofloxacin, cephalosporin, and trimethoprim/sulfamethoxazole (TMP/SMT) was noted in 52.9% (117 cases), 57.0% (126 cases), and 38.9% (86 cases), respectively.
Conclusion
No difference was found in the prevalence of post-UDS UTI based on the presence of pyuria in pre-UDS urinalysis. UDS may be performed even in SCI cases of pre-UDS pyuria without increasing the prevalence of post-UDS UTI if prophylactic antibiotics are administered. TMP/SMT could be used as a first-line antibiotic for the prevention of post-UDS UTI in Korea.
  • 5,298 View
  • 165 Download
Prevalence and Characteristics of Neuropathic Pain in Patients With Spinal Cord Injury Referred to a Rehabilitation Center
Hae Young Kim, Hye Jin Lee, Tae-lim Kim, EunYoung Kim, Daehoon Ham, Jaejoon Lee, Tayeun Kim, Ji Won Shin, Minkyoung Son, Jun Hun Sung, Zee-A Han
Ann Rehabil Med 2020;44(6):438-449.   Published online December 31, 2020
DOI: https://doi.org/10.5535/arm.20081
Objective
To identify the prevalence and characteristics of neuropathic pain (NP) in patients with spinal cord injury (SCI) and to investigate associations between NP and demographic or disease-related variables.
Methods
We retrospectively reviewed medical records of patients with SCI whose pain was classified according to the International Spinal Cord Injury Pain classifications at a single hospital. Multiple statistical analyses were employed. Patients aged <19 years, and patients with other neurological disorders and congenital conditions were excluded.
Results
Of 366 patients, 253 patients (69.1%) with SCI had NP. Patients who were married or had traumatic injury or depressive mood had a higher prevalence rate. When other variables were controlled, marital status and depressive mood were found to be predictors of NP. There was no association between the prevalence of NP and other demographic or clinical variables. The mean Numeric Rating Scale (NRS) of NP was 4.52, and patients mainly described pain as tingling, squeezing, and painful cold. Females and those with below-level NP reported more intense pain. An NRS cut-off value of 4.5 was determined as the most appropriate value to discriminate between patients taking pain medication and those who did not.
Conclusion
In total, 69.1% of patients with SCI complained of NP, indicating that NP was a major complication. Treatment planning for patients with SCI and NP should consider that marital status, mood, sex, and pain subtype may affect NP, which should be actively managed in patients with an NRS ≥4.5.

Citations

Citations to this article as recorded by  
  • Mechanisms and Therapeutic Prospects of Microglia-Astrocyte Interactions in Neuropathic Pain Following Spinal Cord Injury
    Yinuo Liu, Xintong Cai, Bowen Shi, Yajie Mo, Jianmin Zhang, Wenting Luo, Bodong Yu, Xi Li
    Molecular Neurobiology.2025; 62(4): 4654.     CrossRef
  • Comparative outcomes of microsurgical dorsal root entry zone lesioning (DREZotomy) for intractable neuropathic pain in spinal cord and cauda equina injuries
    Bunpot Sitthinamsuwan, Tanawat Ounahachok, Sawanee Pumseenil, Sarun Nunta-aree
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Efficacy of neuromodulation and rehabilitation approaches on pain relief in patients with spinal cord injury: a systematic review and meta-analysis
    Simona Portaro, Angelo Alito, Giulia Leonardi, Nicola Marotta, Adriana Tisano, Daniele Bruschetta, Umile Giuseppe Longo, Antonio Ammendolia, Demetrio Milardi, Alessandro de Sire
    Neurological Sciences.2025;[Epub]     CrossRef
  • Correlation of Severity of Neuropathic Pain in Traumatic Spinal Cord Injury Patients with Sociodemographic and Clinical Characteristics Including Depression and Quality of Life: A Cross-sectional Study
    Arun Yadav, Mrinal Joshi, Shivangi Yadav
    Indian Journal of Physical Medicine and Rehabilitation.2025; 35(2): 128.     CrossRef
  • Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels
    Maryam Hadadi, Mohammad Mojtaba Farazi, Mehrnaz Mehrabani, Mahsa Tashakori-Miyanroudi, Zahra Behroozi
    Scientific Reports.2025;[Epub]     CrossRef
  • Clinical Characteristics of Adults Living with a Spinal Cord Injury Across the Continuum of Care: A Population-Based Cross-Sectional Study
    Matteo Ponzano, Anja Declercq, Melissa Ziraldo, John P. Hirdes
    Journal of Clinical Medicine.2025; 14(9): 3060.     CrossRef
  • Occurrence of neuropathic pain and its characteristics in patients with traumatic spinal cord injury
    Arun Yadav, Mrinal Joshi
    The Journal of Spinal Cord Medicine.2024; 47(6): 952.     CrossRef
  • Post-discharge follow-up of patients with spine trauma in the National Spinal Cord Injury Registry of Iran during the COVID-19 pandemic: Challenges and lessons learned
    Zahra Azadmanjir, Moein Khormali, Mohsen Sadeghi-Naini, Vali Baigi, Habibollah Pirnejad, Mohammad Dashtkoohi, Zahra Ghodsi, Seyed Behnam Jazayeri, Aidin Shakeri, Mahdi Mohammadzadeh, Laleh Bagheri, Mohammad-Sajjad Lotfi, Salman Daliri, Amir Azarhomayoun,
    Chinese Journal of Traumatology.2024; 27(3): 173.     CrossRef
  • Randomised, double-blind, placebo-controlled, parallel-group, multicentric, phase IIA clinical trial for evaluating the safety, tolerability, and therapeutic efficacy of daily oral administration of NFX88 to treat neuropathic pain in individuals with spin
    Pablo V. Escribá, Ángel M. Gil-Agudo, Joan Vidal Samsó, Judith Sánchez-Raya, Sebastián Salvador-de la Barrera, Vanesa Soto-León, Natacha León-Álvarez, Bosco Méndez Ferrer, Miguel David Membrilla-Mesa, Carolina Redondo Galán, Jesús Benito-Penalva, Antonio
    Spinal Cord.2024; 62(8): 454.     CrossRef
  • Low back pain classifications and their associations with disability, quality-of-life, and sociodemographic factors: a comprehensive examination using the PainDETECT questionnaire
    Zachary Gan, Stone Sima, Samuel Lapkin, Ashish D. Diwan
    Current Medical Research and Opinion.2024; 40(8): 1379.     CrossRef
  • Research progress in neuropathic pain after spinal cord injury: a bibliometric study from 2013 to 2024
    Qin Huiqing, Lin Weishan, Gui Yuchang, Tang Yun, Xu Jianwen
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Prevalence and Determinants of Pain in Spinal Cord Injury During Initial Inpatient Rehabilitation: Data From the Dutch Spinal Cord Injury Database
    Tim C. Crul, Marcel W.M. Post, Johanna M.A. Visser-Meily, Janneke M. Stolwijk-Swüste
    Archives of Physical Medicine and Rehabilitation.2023; 104(1): 74.     CrossRef
  • Ectopic expression of Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model
    Yan Fu, Liting Sun, Fengting Zhu, Wei Xia, Ting Wen, Ruilong Xia, Xin Yu, Dan Xu, Changgeng Peng
    Frontiers in Molecular Neuroscience.2023;[Epub]     CrossRef
  • Precision neuromodulation: Promises and challenges of spinal stimulation for multi-modal rehabilitation
    Maria F. Bandres, Jefferson L. Gomes, Gerson N. Moreno Romero, Avery R. Twyman, Jacob Graves McPherson
    Frontiers in Rehabilitation Sciences.2023;[Epub]     CrossRef
  • A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury
    Mu-Lan Xu, Xiang-Bo Wu, Ying Liang, Ning Li, Xu Hu, Xiao-Dong Lin, Miao-Qiao Sun, Chun-Qiu Dai, Dan Niu, Yan-Rong Zhang, Hui Cao, Chen-Guang Zhao, Xiao-Long Sun, Hua Yuan
    Journal of Pain Research.2023; Volume 16: 2619.     CrossRef
  • Feasibility of using remotely delivered Spring Forest Qigong to reduce neuropathic pain in adults with spinal cord injury: a pilot study
    Ann Van de Winckel, Sydney T. Carpentier, Wei Deng, Lin Zhang, Angela Philippus, Ricardo Battaglino, Leslie R. Morse
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • An Exploratory EEG Analysis on the Effects of Virtual Reality in People with Neuropathic Pain Following Spinal Cord Injury
    Yvonne Tran, Philip Austin, Charles Lo, Ashley Craig, James W. Middleton, Paul J. Wrigley, Philip Siddall
    Sensors.2022; 22(7): 2629.     CrossRef
  • Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury
    Zefu Li, Huiying Bai, Ruoyu Zhang, Bohan Chen, Junmin Wang, Bohan Xue, Xiuhua Ren, Jiarui Wang, Yanjie Jia, Weidong Zang, Jian Wang, Xuemei Chen
    European Journal of Neuroscience.2022; 56(2): 3991.     CrossRef
  • Phenotypes of Motor Deficit and Pain after Experimental Spinal Cord Injury
    Volodymyr Krotov, Volodymyr Medvediev, Ibrahim Abdallah, Arseniy Bozhenko, Mykhailo Tatarchuk, Yevheniia Ishchenko, Leonid Pichkur, Serhii Savosko, Vitaliy Tsymbaliuk, Olga Kopach, Nana Voitenko
    Bioengineering.2022; 9(6): 262.     CrossRef
  • Peripheral Immune Dysfunction: A Problem of Central Importance after Spinal Cord Injury
    Marisa Jeffries, Veronica Tom
    Biology.2021; 10(9): 928.     CrossRef
  • 5,785 View
  • 186 Download
  • 22 Web of Science
  • 20 Crossref
Changes in the Trend in Bladder Emptying Methods in Patients With Spinal Cord Injury: A 20-Year Single-Center Retrospective Study
Sang-Wook Oh, Joo Hwan Jung, In Kyoung Cho, Hye Jin Lee, Seung Hyun Kwon, Bum Suk Lee
Ann Rehabil Med 2020;44(3):228-237.   Published online June 30, 2020
DOI: https://doi.org/10.5535/arm.19107
Objective
To review trends in bladder emptying methods over a 20-year period in patients with spinal cord injury (SCI) by severity according to the American Spinal Injury Association impairment scale (AIS).
Methods
Medical records of patients with SCI from 1994 to 1998 (group 1) and from 2012 to 2016 (group 2) were retrospectively reviewed. We classified bladder emptying methods according to the International Spinal Cord dataset. We grouped patients with normal voiding, bladder reflex triggering, and bladder expression as those using voiding without catheter.
Results
A total of 667 patients were included in the analysis. The proportion of patients using voiding without catheter and intermittent catheterization decreased from 67.0% to 30.0% and increased from 26.8% to 54.8%, respectively. In patients with AIS-A and AIS-B, the proportion of patients with intermittent catheterization increased from 32.8% to 73.3%. In patients with AIS-D, the proportion of patients using voiding without catheter and intermittent catheterization decreased from 88.5% to 68.9% and increased from 11.5% to 26.8%, respectively. In group 2, among 111 patients with AIS-D using voiding without catheter at admission, 8 (7.2%) switched to intermittent catheterization at discharge due to decreased bladder volume, increased post-voiding residual urine, or incontinence.
Conclusion
Over the past 20 years, trends in bladder emptying methods in patients with SCI changed from voiding without catheter to intermittent catheterization in Korea. This was especially prominent in patients with AIS-A, AIS-B, and AIS-C. Even in patients with AIS-D, the use of intermittent catheterization at hospital discharge increased.

Citations

Citations to this article as recorded by  
  • Changes in bladder emptying during inpatient rehabilitation after spinal cord injury and predicting factors: data from the Dutch Spinal Cord Injury Database
    Claire G. Poublon, Eline W. M. Scholten, Michel I. A. Wyndaele, Marcel W. M. Post, Janneke M. Stolwijk-Swüste
    Spinal Cord.2023; 61(11): 624.     CrossRef
  • Should We Delay Urodynamic Study When Patients With Spinal Cord Injury Have Asymptomatic Pyuria?
    EunYoung Kim, Hye Jin Lee, Onyoo Kim, In Suk Park, Bum-Suk Lee
    Annals of Rehabilitation Medicine.2021; 45(3): 178.     CrossRef
  • 5,213 View
  • 114 Download
  • 2 Web of Science
  • 2 Crossref
Energy Efficiency and Patient Satisfaction of Gait With Knee-Ankle-Foot Orthosis and Robot (ReWalk)-Assisted Gait in Patients With Spinal Cord Injury
Seung Hyun Kwon, Bum Suk Lee, Hye Jin Lee, Eun Joo Kim, Jung Ah Lee, Sung Phil Yang, Tae Young Kim, Han Ram Pak, Hyun Ki Kim, Hae Young Kim, Joo Hwan Jung, Sang Wook Oh
Ann Rehabil Med 2020;44(2):131-141.   Published online April 29, 2020
DOI: https://doi.org/10.5535/arm.2020.44.2.131
Objective
To compare the energy efficiency of gait with knee-ankle-foot orthosis (KAFO) and robot-assisted gait and to develop a usability questionnaire to evaluate the satisfaction of walking devices in paraplegic patients with spinal cord injuries.
Methods
Thirteen patients with complete paraplegia participated and 10 completed the evaluation. They were trained to walk with KAFO (KAFO-gait) or a ReWalk robot (ReWalk-gait) for 4 weeks (20 sessions). After a 2-week wash-out period, they switched walking devices and underwent 4 additional weeks of training. Two evaluations were performed (after 2 and 4 weeks) following the training periods for each walking device, using the 6-minute walking test (6MWT) and 30-minute walking test (30MWT). The spatiotemporal variables (walking distance, velocity, and cadence) and energy expenditure (heart rate, maximal heart rate, the physiologic cost index, oxygen consumption, metabolic equivalents, and energy efficiency) were evaluated duringthe 6MWT and 30MWT. A usability evaluation questionnaire for walking devices was developed based on the International Organization for Standardization/International Electrotechnical Commission guidelines through expert consultation.
Results
The ReWalk-gait presented significant advantages in energy efficiency compared to KAFO-gait in the 6MWT and 30MWT; however, there were no differences in walking distance or speed in the 30MWT between ReWalk-gait and KAFOgait. The usability test demonstrated that ReWalk-gait was not superior to KAFO-gait in terms of safety, efficacy, efficiency, or patient satisfaction.
Conclusion
The robot (ReWalk) enabled patients with paraplegia to walk with lower energy consumption compared to KAFO, but the ReWalk-gait was not superior to KAFO-gaitin terms of patient satisfaction.

Citations

Citations to this article as recorded by  
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    Journal of Shanghai Jiaotong University (Science).2025; 30(1): 197.     CrossRef
  • Consumer views of functional electrical stimulation and robotic exoskeleton in SCI rehabilitation: A mini review
    Yalian Pei, Mari Tobita, Benjamin Dirlikov, Dannae Arnold, Candace Tefertiller, Ashraf Gorgey
    Artificial Organs.2025; 49(5): 729.     CrossRef
  • Flexible exoskeleton-assisted training enhances lower limb motor function after stroke: a systematic review and meta-analysis
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    Journal of Neurology.2025;[Epub]     CrossRef
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    Journal of Shanghai Jiaotong University (Science).2024; 29(1): 1.     CrossRef
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    Axel Ruetz, Tom DiBello, Chris Toelle, Bea Hemmen, Jason Wening, Eric Weber, Frank Braatz, Tobias Winkler, Friedemann Steinfeldt, Marina Umari, Rüdiger Rupp, Sascha Kluge, Alexander Krebs, Shane R. Wurdeman
    Disability and Rehabilitation.2024; 46(17): 4019.     CrossRef
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    Hye Suk Kim
    Textile Research Journal.2024; 94(3-4): 390.     CrossRef
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    Jiwon Chung, Wujun Tang, Jeong Eun Yoon, Suhyun Ha, Ju Young Kang, Sumin Helen Koo, Sathishkumar Veerappampalayam Easwaramoorthy
    PLOS ONE.2024; 19(3): e0299434.     CrossRef
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    Wei Meng, Chang Zhu, Haojie Liu, Quan Liu, Sheng Xie
    IEEE Transactions on Medical Robotics and Bionics.2024; 6(2): 384.     CrossRef
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    Journal of NeuroEngineering and Rehabilitation.2024;[Epub]     CrossRef
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    Smart Materials and Structures.2024; 33(8): 085041.     CrossRef
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    Jiwon Chung, Jung Eun Yoon, Soah Park, Hyunbin Won, Suhyun Ha, Sumin Helen Koo
    International Journal of Industrial Ergonomics.2024; 103: 103616.     CrossRef
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    Guo-Shing Huang, Meng-Hua Yen, Chia-Chun Chang, Chung-Liang Lai, Chi-Chun Chen
    Biomedical Physics & Engineering Express.2024; 10(5): 055039.     CrossRef
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    Journal of Industrial Textiles.2024;[Epub]     CrossRef
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    Healthcare.2023; 11(5): 643.     CrossRef
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    Wenjie Ling
    Sustainable Energy Technologies and Assessments.2023; 56: 103123.     CrossRef
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    Francesco Zanatta, Patrizia Steca, Cira Fundarò, Anna Giardini, Guido Felicetti, Monica Panigazzi, Giovanni Arbasi, Cesare Grilli, Marco D’Addario, Antonia Pierobon, Walid Kamal Abdelbasset
    PLOS ONE.2023; 18(3): e0282925.     CrossRef
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    Chaoyang Zhang, Ning Li, Xiali Xue, Xia Lu, Danjie Li, Qiaomei Hong
    Gait & Posture.2023; 102: 64.     CrossRef
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  • The Cardiorespiratory Demands of Treadmill Walking with and without the Use of Ekso GT™ within Able-Bodied Participants: A Feasibility Study
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    International Journal of Environmental Research and Public Health.2022; 19(10): 6176.     CrossRef
  • The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications
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  • Comparing walking with knee-ankle-foot orthoses and a knee-powered exoskeleton after spinal cord injury: a randomized, crossover clinical trial
    Antonio Rodríguez-Fernández, Joan Lobo-Prat, Rafael Tarragó, Diego Chaverri, Xavier Iglesias, Lluis Guirao-Cano, Josep M. Font-Llagunes
    Scientific Reports.2022;[Epub]     CrossRef
  • Gait robot-assisted rehabilitation in persons with spinal cord injury: A scoping review
    Giulia Stampacchia, Valeria Gazzotti, Matteo Olivieri, Elisa Andrenelli, Donatella Bonaiuti, Rocco Salvatore Calabro, Simona Maria Carmignano, Anna Cassio, Cira Fundaro, Isabella Companini, David Mazzoli, Simona Cerulli, Carmelo Chisari, Valentina Colombo
    NeuroRehabilitation.2022; 51(4): 609.     CrossRef
  • A Study on Energy Efficiency in Walking and Stair Climbing for Elderly Wearing Complex Muscle Support System
    Jang-hoon Shin, Hye-Kang Park, Joonyoung Jung, Dong-Woo Lee, Hyung Cheol Shin, Hwang-Jae Lee, Wan-Hee Lee
    Physical Therapy Rehabilitation Science.2022; 11(4): 478.     CrossRef
  • Effects of Wearable Powered Exoskeletal Training on Functional Mobility, Physiological Health and Quality of Life in Non-ambulatory Spinal Cord Injury Patients
    Hyeon Seong Kim, Jae Hyeon Park, Ho Seok Lee, Jae Young Lee, Ji Won Jung, Si-Bog Park, Dong Jin Hyun, Sangin Park, JuYoung Yoon, Hyunseop Lim, Yun Young Choi, Mi Jung Kim
    Journal of Korean Medical Science.2021;[Epub]     CrossRef
  • The Effects of Powered Exoskeleton Gait Training on Cardiovascular Function and Gait Performance: A Systematic Review
    Damien Duddy, Rónán Doherty, James Connolly, Stephen McNally, Johnny Loughrey, Maria Faulkner
    Sensors.2021; 21(9): 3207.     CrossRef
  • Effectiveness of powered exoskeleton use on gait in individuals with cerebral palsy: A systematic review
    Lucinda Rose Bunge, Ashleigh Jade Davidson, Benita Roslyn Helmore, Aleksandra Daniella Mavrandonis, Thomas David Page, Tegan Rochelle Schuster-Bayly, Saravana Kumar, Peter Schwenkreis
    PLOS ONE.2021; 16(5): e0252193.     CrossRef
  • 10,836 View
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Effects of Combined Upper Limb Robotic Therapy in Patients With Tetraplegic Spinal Cord Injury
Joo Hwan Jung, Hye Jin Lee, Duk Youn Cho, Jung-Eun Lim, Bum Suk Lee, Seung Hyun Kwon, Hae Young Kim, Su Jeong Lee
Ann Rehabil Med 2019;43(4):445-457.   Published online August 31, 2019
DOI: https://doi.org/10.5535/arm.2019.43.4.445
Objective
To confirm the effects of combined upper limb robotic therapy (RT) as compared to conventional occupational therapy (OT) in tetraplegic spinal cord injury (SCI) patients and to suggest the optimized treatment guidelines of combined upper limb RT.
Methods
After subject recruitment and screening for eligibility, the baseline evaluation for outcome measures were performed. We evaluated the Graded and Redefined Assessment of Strength, Sensibility, and Prehension (GRASSP), the American Spinal Injury Association upper extremity motor score, grip and pinch strength, and the Spinal Cord Independence Measurement III (SCIM-III). In this study, the pre-tested participants were divided randomly into the RT and OT group. The utilized interventions included combined upper limb RT using ArmeoPower and Amadeo (RT group), or conventional OT (OT group) in addition to daily inpatient rehabilitation program. The participants underwent 40 minutes×3 sessions×5 weeks of interventions.
Results
A total of 30 tetraplegic SCI patients completed entire study program. After 5 weeks of intervention, both groups demonstrated increases in GRASSP-strength and SCIM-III. The manual muscle test scores of elbow flexion, elbow extension, 2-5th metacarpophalangeal extension, and SCIM-III subscores of bathing-upper, dressing-upper, and grooming as well as the GRASSP-qualitative prehension score were noted to have been significantly increased in the RT group as evaluated. The OT group showed improvements in the GRASSP-quantitative prehension score and some items in grip and pinch strength. There was no significant difference between the two groups in almost all measurements except for the SCIM-III bathing-upper subscore.
Conclusion
Combined upper limb RT demonstrated beneficial effects on the upper limb motor function in patients with tetraplegic SCI, which were comparable with conventional OT.

Citations

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  • Anxiety and Depression in Pediatric-Onset Traumatic Spinal Cord Injury: A Systematic Review
    Mohammad Mofatteh, Mohammad Sadegh Mashayekhi, Saman Arfaie, Yimin Chen, Armaan K. Malhotra, Georgios P. Skandalakis, Mohammed Ali Alvi, Fardad T. Afshari, Shakila Meshkat, Famu Lin, Ebtesam Abdulla, Ayush Anand, Xuxing Liao, Roger S. McIntyre, Carlo Sant
    World Neurosurgery.2024; 184: 267.     CrossRef
  • Technology-Assisted Upper Limb Therapy (TAULT): Evaluation of Clinical Practice at a Specialised Centre for Spinal Cord Injury in Switzerland
    Daniela B. Kuchen, Beatrice Hubacher, Andris Ladner, Inge-Marie Velstra, Mario Widmer
    Healthcare.2023; 11(23): 3055.     CrossRef
  • Reliability Validity and Responsiveness of the Spinal Cord Independence Measure 4th Version in a Multicultural Setup
    Amiram Catz, Malka Itzkovich, Keren Elkayam, Dianne Michaeli, Ilana Gelernter, Yoav Benjamini, Harvinder Singh Chhabra, Luigi Tesio, Einat Engel-Haber, Emiliana Bizzarini, Claudio Pilati, Giulio Del Popolo, Ilaria Baroncini, Nan Liu, Paulo Margalho, Thaba
    Archives of Physical Medicine and Rehabilitation.2022; 103(3): 430.     CrossRef
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    Lorna C. Kahn, Adam G. Evans, Elspeth J. R. Hill, Ida K. Fox
    Spinal Cord Series and Cases.2022;[Epub]     CrossRef
  • The Impact of Robotic Therapy on the Self-Perception of Upper Limb Function in Cervical Spinal Cord Injury: A Pilot Randomized Controlled Trial
    V. Lozano-Berrio, M. Alcobendas-Maestro, B. Polonio-López, A. Gil-Agudo, A. de la Peña-González, A. de los Reyes-Guzmán
    International Journal of Environmental Research and Public Health.2022; 19(10): 6321.     CrossRef
  • The Outcomes of Robotic Rehabilitation Assisted Devices Following Spinal Cord Injury and the Prevention of Secondary Associated Complications
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    Tao Zhang, Kang Li, Zi-Lu Zhang, Kai Gao, Chao-Liang Lv
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    Lisa A. Harvey, Joanne V. Glinsky, Jackie Chu
    Spinal Cord.2021; 59(7): 705.     CrossRef
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    Muhammad Ahsan Gull, Shaoping Bai, Jakob Udby Blicher, Tobias Glaston Staermose
    Journal of Medical Devices.2021;[Epub]     CrossRef
  • Upper Limb Robotic Rehabilitation for Patients with Cervical Spinal Cord Injury: A Comprehensive Review
    Giovanni Morone, Alessandro de Sire, Alex Martino Cinnera, Matteo Paci, Luca Perrero, Marco Invernizzi, Lorenzo Lippi, Michela Agostini, Irene Aprile, Emanuela Casanova, Dario Marino, Giuseppe La Rosa, Federica Bressi, Silvia Sterzi, Daniele Giansanti, Al
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    Drug Metabolism and Personalized Therapy.2020;[Epub]     CrossRef
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Clinical Characteristics of Proper Robot-Assisted Gait Training Group in Non-ambulatory Subacute Stroke Patients
Soo Jeong Kim, Hye Jin Lee, Seung Won Hwang, Hannah Pyo, Sung Phil Yang, Mun-Hee Lim, Gyu Lee Park, Eun Joo Kim
Ann Rehabil Med 2016;40(2):183-189.   Published online April 25, 2016
DOI: https://doi.org/10.5535/arm.2016.40.2.183
Objective

To identify the clinical characteristics of proper robot-assisted gait training group using exoskeletal locomotor devices in non-ambulatory subacute stroke patients.

Methods

A total of 38 stroke patients were enrolled in a 4-week robotic training protocol (2 sessions/day, 5 times/week). All subjects were evaluated for their general characteristics, Functional Ambulatory Classification (FAC), Fugl-Meyer Scale (FMS), Berg Balance Scale (BBS), Modified Rankin Scale (MRS), Modified Barthel Index (MBI), and Mini-Mental Status Examination (MMSE) at 0, 2, and 4 weeks. Statistical analysis were performed to determine significant clinical characteristics for improvement of gait function after robot-assisted gait training.

Results

Paired t-test showed that all functional parameters except MMSE were improved significantly (p<0.05). The duration of disease and baseline BBS score were significantly (p<0.05) correlated with FAC score in multiple regression models. Receiver operating characteristic (ROC) curve showed that a baseline BBS score of '9' was a cutoff value (AUC, 0.966; sensitivity, 91%–100%; specificity, 85%). By repeated-measures ANOVA, the differences in improved walking ability according to time were significant between group of patients who had baseline BBS score of '9' and those who did not have baseline BBS score of '9'

Conclusion

Our results showed that a baseline BBS score above '9' and a short duration of disease were highly correlated with improved walking ability after robot-assisted gait training. Therefore, baseline BBS and duration of disease should be considered clinically for gaining walking ability in robot-assisted training group.

Citations

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  • Maximizing stroke recovery with advanced technologies: A comprehensive assessment of robot-assisted, EMG-Controlled robotics, virtual reality, and mirror therapy interventions
    Faisal Amin, Asim Waris, Javaid Iqbal, Syed Omer Gilani, M. Zia Ur Rehman, Shafaq Mushtaq, Niaz Bahadur Khan, M. Ijaz Khan, Mohammed Jameel, Nissren Tamam
    Results in Engineering.2024; 21: 101725.     CrossRef
  • Factors affecting the efficiency of walking independence in patients with subacute stroke following robot-assisted gait training with conventional rehabilitation
    Yoshiaki Maki, Takuma Ii, Masanari Yamada, Shigeo Tanabe
    International Journal of Rehabilitation Research.2024; 47(1): 26.     CrossRef
  • Identifying the characteristics of patients with stroke who have difficulty benefiting from gait training with the hybrid assistive limb: a retrospective cohort study
    Shingo Taki, Takeshi Imura, Tsubasa Mitsutake, Yuji Iwamoto, Ryo Tanaka, Naoki Imada, Hayato Araki, Osamu Araki
    Frontiers in Neurorobotics.2024;[Epub]     CrossRef
  • Effects of robot-assisted walking training on balance, motor function, and ADL depending on severity levels in stroke patients
    Soo Yong Lee, Yu Sik Choi, Min Hyuk Kim, Woo Nam Chang
    Technology and Health Care.2024; 32(5): 3293.     CrossRef
  • Gait Performance and Brain Activity Are Improved by Gait Automatization during Robot-Assisted Gait Training in Patients with Burns: A Prospective, Randomized, Single-Blinded Study
    Seung Yeol Lee, Jisu Seo, Cheong Hoon Seo, Yoon Soo Cho, So Young Joo
    Journal of Clinical Medicine.2024; 13(16): 4838.     CrossRef
  • Therapeutic Effect of High-Definition Transcranial Direct Current Stimulation Combined with Suspension Exercise Training on Lower Limb Motor Function of Stroke Patients
    Haiquan ZHANG, Chuan HU, Lei HUANG, Wei LU, Xin WANG
    Rehabilitation Medicine.2024; 34(2): 110.     CrossRef
  • Control strategies used in lower limb exoskeletons for gait rehabilitation after brain injury: a systematic review and analysis of clinical effectiveness
    Jesús de Miguel-Fernández, Joan Lobo-Prat, Erik Prinsen, Josep M. Font-Llagunes, Laura Marchal-Crespo
    Journal of NeuroEngineering and Rehabilitation.2023;[Epub]     CrossRef
  • Optimal Intervention Timing for Robotic-Assisted Gait Training in Hemiplegic Stroke
    Lingchao Xie, Bu Hyun Yoon, Chanhee Park, Joshua (Sung) H. You
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  • Effect of Robot Assisted Gait Training on Motor and Walking Function in Patients with Subacute Stroke: A Random Controlled Study
    Dong-Xia Li, Fu-Bing Zha, Jian-Jun Long, Fang Liu, Jia Cao, Yu-Long Wang
    Journal of Stroke and Cerebrovascular Diseases.2021; 30(7): 105807.     CrossRef
  • Exoskeleton for post-stroke recovery of ambulation (ExStRA): study protocol for a mixed-methods study investigating the efficacy and acceptance of an exoskeleton-based physical therapy program during stroke inpatient rehabilitation
    Dennis R. Louie, William B. Mortenson, Melanie Durocher, Robert Teasell, Jennifer Yao, Janice J. Eng
    BMC Neurology.2020;[Epub]     CrossRef
  • Effectiveness of robot-assisted gait training on patients with burns: a preliminary study
    So Young Joo, Seung Yeol Lee, Yoon Soo Cho, Kuem Ju Lee, Sang-Hyun Kim, Cheong Hoon Seo
    Computer Methods in Biomechanics and Biomedical Engineering.2020; 23(12): 888.     CrossRef
  • Assessing Stiffness, Joint Torque and ROM for Paretic and Non-Paretic Lower Limbs during the Subacute Phase of Stroke Using Lokomat Tools
    Betsy D. M. Chaparro-Rico, Daniele Cafolla, Paolo Tortola, Giuseppe Galardi
    Applied Sciences.2020; 10(18): 6168.     CrossRef
  • Robot-assisted gait training for balance and lower extremity function in patients with infratentorial stroke: a single-blinded randomized controlled trial
    Ha Yeon Kim, Joon-Ho Shin, Sung Phil Yang, Min A. Shin, Stephanie Hyeyoung Lee
    Journal of NeuroEngineering and Rehabilitation.2019;[Epub]     CrossRef
  • Effect of ankle-foot orthosis on functional mobility and dynamic balance of patients after stroke
    Gabriela Vieira de Paula, Taís Regina da Silva, Juli Thomaz de Souza, Gustavo José Luvizutto, Silméia Garcia Zanati Bazan, Gabriel Pinheiro Modolo, Fernanda Cristina Winckler, Letícia Cláudia de Oliveira Antunes, Luís Cuadrado Martin, Rafael Dalle Molle d
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    Sung Il Hwang
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    Bio-Algorithms and Med-Systems.2017; 13(1): 37.     CrossRef
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Comparison of Fat Mass Percentage and Body Mass Index in Koreans With Spinal Cord Injury According to the Severity and Duration of Motor Paralysis
Sang Hoon Han, Bum-Suk Lee, Hyun Soo Choi, Min-Soo Kang, Bo Ra Kim, Zee-A Han, Hye Jin Lee
Ann Rehabil Med 2015;39(3):384-392.   Published online June 30, 2015
DOI: https://doi.org/10.5535/arm.2015.39.3.384
Objective

To analyze the relationship of the change in fat mass percentage (FMP) and body mass index (BMI) with the change in obesity rate according to gender, extent of spinal cord injury (SCI) and the duration.

Methods

The retrospective study was conducted with medical records of 915 patients. FMP was calculated with BMI and bioelectrical impedance analysis (BIA). Statistical analysis of the relationship between FMP and gender, extent of SCI and the duration after SCI was done.

Results

FMP increased in relation to the duration. The mean FMP was higher in the motor complete tetraplegia group, as compared to the motor incomplete group. The rate of obesity was 69.8% with cutoff FMP values of over 22% and 35% for male and female patients, respectively. Rate of obesity was correlated with the duration after SCI and degree of paralysis. The rate of obesity was 17.1% with a cutoff value of BMI 25 kg/m2 and 51.3% with a cutoff value of 22 kg/m2. For evaluation of the diagnostic value of BMI to predict obesity according to FMP standards, a cutoff value of 25 kg/m2 showed a sensitivity level of 22.3% and specificity level of 94.9%. When the cutoff level for BMI was set at 22 kg/m2, the sensitivity and specificity were 59.3% and 67.0%, respectively.

Conclusion

In Korean SCI patients, FMP showed good correlation with the duration of SCI and the extent of SCI, while BMI did not. Especially in the motor complete tetraplegia group, the diagnostic value of BMI decreased as the duration after SCI increased. This study suggested that FMP could be used complementarily when evaluating the obesity of SCI patients.

Citations

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  • Association Between Sarcopenic Obesity and Activities of Daily Living in Individuals with Spinal Cord Injury
    Ryu Ishimoto, Hirotaka Mutsuzaki, Yukiyo Shimizu, Ryoko Takeuchi, Shuji Matsumoto, Yasushi Hada
    Journal of Clinical Medicine.2024; 13(23): 7071.     CrossRef
  • Prevalence of Sarcopenic Obesity and Factors Influencing Body Composition in Persons with Spinal Cord Injury in Japan
    Ryu Ishimoto, Hirotaka Mutsuzaki, Yukiyo Shimizu, Hiroshi Kishimoto, Ryoko Takeuchi, Yasushi Hada
    Nutrients.2023; 15(2): 473.     CrossRef
  • Body Composition and Metabolic Assessment After Motor Complete Spinal Cord Injury: Development of a Clinically Relevant Equation to Estimate Body Fat
    David R. Gater, Gary J. Farkas, David R. Dolbow, Arthur Berg, Ashraf S. Gorgey
    Topics in Spinal Cord Injury Rehabilitation.2021; 27(1): 11.     CrossRef
  • Pathophysiology of Neurogenic Obesity After Spinal Cord Injury
    David R. Gater, Gary J. Farkas, Eduard Tiozzo
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  • Body Composition According to Spinal Cord Injury Level: A Systematic Review and Meta-Analysis
    Peter Francis Raguindin, Alessandro Bertolo, Ramona Maria Zeh, Gion Fränkl, Oche Adam Itodo, Simona Capossela, Lia Bally, Beatrice Minder, Mirjam Brach, Inge Eriks-Hoogland, Jivko Stoyanov, Taulant Muka, Marija Glisic
    Journal of Clinical Medicine.2021; 10(17): 3911.     CrossRef
  • Classification of obesity, cardiometabolic risk, and metabolic syndrome in adults with spinal cord injury
    Amy M. Yahiro, Brooks C. Wingo, Sujit Kunwor, Jason Parton, Amy C. Ellis
    The Journal of Spinal Cord Medicine.2020; 43(4): 485.     CrossRef
  • Are Body Composition, Strength, and Functional Independence Similarities Between Spinal Cord Injury Classifications? A Discriminant Analysis
    Rodrigo Rodrigues Gomes Costa, Rodrigo Luiz Carregaro, Frederico Ribeiro Neto
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  • Body Composition in Swiss Elite Wheelchair Athletes
    Joelle Leonie Flueck
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    Gary J. Farkas, David R. Gater
    The Journal of Spinal Cord Medicine.2018; 41(4): 378.     CrossRef
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Nerve Conduction Studies of Median Motor Nerve and Median Sensory Branches According to the Severity of Carpal Tunnel Syndrome
Hye Jin Lee, Hee Kyu Kwon, Dong Hwee Kim, Sung Bom Pyun
Ann Rehabil Med 2013;37(2):254-262.   Published online April 30, 2013
DOI: https://doi.org/10.5535/arm.2013.37.2.254
Objective

To evaluate each digital branch of the median sensory nerve and motor nerves to abductor pollicis brevis (APB) and 2nd lumbrical (2L) according to the severity of carpal tunnel syndrome (CTS).

Methods

A prospective study was performed in 67 hands of 41 patients with CTS consisting of mild, 23; moderate, 27; and severe cases, 17. Compound muscle action potentials (CMAPs) were obtained from APB and 2L, and median sensory nerve action potentials (SNAPs) were recorded from the thumb to the 4th digit. Parameters analyzed were latency of the median CMAP, latency difference of 2L and first palmar interosseous (PI), as well as latency and baseline to peak amplitude of the median SNAPs.

Results

The onset and peak latencies of the median SNAPs revealed significant differences only in the 2nd digit, according to the severity of CTS, and abnormal rates of the latencies were significantly lower in the 2nd digit to a mild degree. The amplitude of SNAP and sensory nerve conduction velocities were more preserved in the 2nd digit in mild CTS and more affected in the 4th digit in severe CTS. CMAPs were not evoked with APB recording in 4 patients with severe CTS, but obtained in all patients with 2L recording. 2L-PI showed statistical significance according to the severity of CTS.

Conclusion

The branch to the 4th digit was mostly involved and the branch to the 2nd digit and 2L were less affected in the progress of CTS. The second digit recorded SNAPs and 2L recorded CMAPs would be valuable in the evaluation of severe CTS.

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    PLOS ONE.2024; 19(4): e0300044.     CrossRef
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