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Spinal cord injury

Correction: Effects of Resistance Circuit Training on Health-Related Physical Fitness in People With Paraplegia: A Pilot Randomized Controlled Trial
Minkyoung Son, Hyejin Lee, Bum-Suk Lee, EunYoung Kim, Hyeyeong Yun, Seck Jin Kim, JaeHak Kim, Seung-Mo Jin, Seon-Deok Eun
Ann Rehabil Med 2022;46(4):219.   Published online August 31, 2022
DOI: https://doi.org/10.5535/arm.22012.e
Corrects: Ann Rehabil Med 2022;46(2):87
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Original Articles

Spinal cord injury

Effects of Resistance Circuit Training on Health-Related Physical Fitness in People With Paraplegia: A Pilot Randomized Controlled Trial
Minkyoung Son, Hyejin Lee, Bum-Suk Lee, EunYoung Kim, Hyeyeong Yun, Seck Jin Kim, JaeHak Kim, Seung-Mo Jin, Seon-Deok Eun
Ann Rehabil Med 2022;46(2):87-96.   Published online April 30, 2022
DOI: https://doi.org/10.5535/arm.22012
Correction in: Ann Rehabil Med 2022;46(4):219
Objective
To evaluate the efficacy and safety of 8 weeks of resistance circuit training in people with paraplegia due to spinal cord injury.
Methods
Participants were randomized into experimental and control groups. Although the intensity and sequence of movements of the exercise programs were identical in both groups, the resting time between sets was limited to 1 minute in the experimental group. In the control group, the participants were allowed to rest until they were comfortable. Both groups received 8 weeks of training twice per week. Before and after the program, muscle mass, body fat percentage, fat mass, blood pressure, heart rate, muscle strength and muscular endurance were evaluated, and 6-minute propulsion test was conducted. Additionally, the safety of the program was assessed.
Results
Twenty-two individuals with paraplegia were enrolled (11 in each group). After the training program, the experimental group showed a significant decrease in the resting blood pressure and improvement in the upper extremity muscle mass, strength, and endurance (p<0.05). Each variable showed significant inter-group differences (p<0.05). Furthermore, none of the participants showed autonomic adverse events, musculoskeletal side effects, or discomfort.
Conclusion
The results show that resistance circuit training programs with short resting intervals are superior to the usual resistance exercise programs in improving the blood pressure and physical strength and are safe for people with upper thoracic level injuries at T6 or higher.

Citations

Citations to this article as recorded by  
  • Effectiveness of a Community-Based Exercise Program for Ambulatory Individuals With Spinal Cord Injury: A Randomized Controlled Trial
    Sungchul Huh, Yuna Kim, Hyun-Yoon Ko, Mi Sook Yun, Yong Il Shin, Jung Lim Lee, Sung-Hwa Ko
    Archives of Physical Medicine and Rehabilitation.2025; 106(4): 481.     CrossRef
  • A three-arm randomized controlled trial of aerobic and resistance training in women with spinal cord injuries: Effects on physical fitness and pulmonary function
    Amir Hossein Haghighi, Atefeh Ahmadi, Roya Askari, Hadi Shahrabadi, Jeremy A. Moody, Joshua M. Miller, Filipe Clemente, Paulo Gentil
    Heliyon.2024; 10(13): e32538.     CrossRef
  • Effectiveness of Circuit and Fartlek Exercises to Increase Aerobic Endurance in Adolescent Futsal Players
    M Haris Satria, Juhanis Juhanis, Mohamad Da'i, Lalu Moh Yudha Isnaini, Khaerul Anam, Karlina Dwijayanti
    International Journal of Disabilities Sports and Health Sciences.2024; 7(4): 782.     CrossRef
  • Multicomponent Training in Progressive Phases Improves Functional Capacity, Physical Capacity, Quality of Life, and Exercise Motivation in Community-Dwelling Older Adults: A Randomized Clinical Trial
    Emilio Jofré-Saldía, Álvaro Villalobos-Gorigoitía, Cristián Cofré-Bolados, Gerson Ferrari, Gemma María Gea-García
    International Journal of Environmental Research and Public Health.2023; 20(3): 2755.     CrossRef
  • Evaluation of a Physical-Psychological Integrative (PPI) intervention for community-dwelling spinal cord injury survivors: Study protocol of a preliminary randomized controlled trial
    Yan Li, Arnold Wong, Wai Man Chung, Mengqi Li, Alex Molasiotis, Daniel Bressington, Christina Zong-Hao Ma, Patrick Pui Kin Kor, Wing Fai Yeung, Victor Afamefuna Egwuonwu
    PLOS ONE.2023; 18(3): e0282846.     CrossRef
  • 7,596 View
  • 181 Download
  • 3 Web of Science
  • 5 Crossref

Spinal cord injury

Should We Delay Urodynamic Study When Patients With Spinal Cord Injury Have Asymptomatic Pyuria?
EunYoung Kim, Hye Jin Lee, Onyoo Kim, In Suk Park, Bum-Suk Lee
Ann Rehabil Med 2021;45(3):178-185.   Published online June 14, 2021
DOI: https://doi.org/10.5535/arm.20241
Objective
To assess the incidence of urinary tract infection (UTI) with post-urodynamic study (post-UDS) in patients with spinal cord injury (SCI) and study its relationship with pre-UDS pyuria.
Methods
Patients with SCI who were hospitalized and underwent UDS during a 4-year period were reviewed. Patients with pre-test lower urinary tract symptoms were excluded. Urinalysis and urine culture were performed before and 24 hours after UDS. Prophylactic antibiotics were administered for 5 days starting from the morning of the UDS. UTI was defined as bacteriuria with accompanying symptoms.
Results
Of 399 patients reviewed, 209 (52.4%) had pyuria in pre-UDS urinalysis, and 257 (64.4%) had bacteriuria in pre-UDS culture. Post-UDS UTI occurred in 6 (1.5%) individuals who all complained of fever: 5 (2.4%) of the post-UDS UTI cases occurred in patients with pre-UDS pyuria, and 1 (0.5%) in a person without. The differences between groups were not statistically significant (p=0.218). Of 221 patients with bacteriuria (gram-negative isolates) on pre-UDS culture, resistance to ciprofloxacin, cephalosporin, and trimethoprim/sulfamethoxazole (TMP/SMT) was noted in 52.9% (117 cases), 57.0% (126 cases), and 38.9% (86 cases), respectively.
Conclusion
No difference was found in the prevalence of post-UDS UTI based on the presence of pyuria in pre-UDS urinalysis. UDS may be performed even in SCI cases of pre-UDS pyuria without increasing the prevalence of post-UDS UTI if prophylactic antibiotics are administered. TMP/SMT could be used as a first-line antibiotic for the prevention of post-UDS UTI in Korea.
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Prevalence and Characteristics of Neuropathic Pain in Patients With Spinal Cord Injury Referred to a Rehabilitation Center
Hae Young Kim, Hye Jin Lee, Tae-lim Kim, EunYoung Kim, Daehoon Ham, Jaejoon Lee, Tayeun Kim, Ji Won Shin, Minkyoung Son, Jun Hun Sung, Zee-A Han
Ann Rehabil Med 2020;44(6):438-449.   Published online December 31, 2020
DOI: https://doi.org/10.5535/arm.20081
Objective
To identify the prevalence and characteristics of neuropathic pain (NP) in patients with spinal cord injury (SCI) and to investigate associations between NP and demographic or disease-related variables.
Methods
We retrospectively reviewed medical records of patients with SCI whose pain was classified according to the International Spinal Cord Injury Pain classifications at a single hospital. Multiple statistical analyses were employed. Patients aged <19 years, and patients with other neurological disorders and congenital conditions were excluded.
Results
Of 366 patients, 253 patients (69.1%) with SCI had NP. Patients who were married or had traumatic injury or depressive mood had a higher prevalence rate. When other variables were controlled, marital status and depressive mood were found to be predictors of NP. There was no association between the prevalence of NP and other demographic or clinical variables. The mean Numeric Rating Scale (NRS) of NP was 4.52, and patients mainly described pain as tingling, squeezing, and painful cold. Females and those with below-level NP reported more intense pain. An NRS cut-off value of 4.5 was determined as the most appropriate value to discriminate between patients taking pain medication and those who did not.
Conclusion
In total, 69.1% of patients with SCI complained of NP, indicating that NP was a major complication. Treatment planning for patients with SCI and NP should consider that marital status, mood, sex, and pain subtype may affect NP, which should be actively managed in patients with an NRS ≥4.5.

Citations

Citations to this article as recorded by  
  • Mechanisms and Therapeutic Prospects of Microglia-Astrocyte Interactions in Neuropathic Pain Following Spinal Cord Injury
    Yinuo Liu, Xintong Cai, Bowen Shi, Yajie Mo, Jianmin Zhang, Wenting Luo, Bodong Yu, Xi Li
    Molecular Neurobiology.2025; 62(4): 4654.     CrossRef
  • Comparative outcomes of microsurgical dorsal root entry zone lesioning (DREZotomy) for intractable neuropathic pain in spinal cord and cauda equina injuries
    Bunpot Sitthinamsuwan, Tanawat Ounahachok, Sawanee Pumseenil, Sarun Nunta-aree
    Neurosurgical Review.2025;[Epub]     CrossRef
  • Efficacy of neuromodulation and rehabilitation approaches on pain relief in patients with spinal cord injury: a systematic review and meta-analysis
    Simona Portaro, Angelo Alito, Giulia Leonardi, Nicola Marotta, Adriana Tisano, Daniele Bruschetta, Umile Giuseppe Longo, Antonio Ammendolia, Demetrio Milardi, Alessandro de Sire
    Neurological Sciences.2025; 46(7): 2995.     CrossRef
  • Correlation of Severity of Neuropathic Pain in Traumatic Spinal Cord Injury Patients with Sociodemographic and Clinical Characteristics Including Depression and Quality of Life: A Cross-sectional Study
    Arun Yadav, Mrinal Joshi, Shivangi Yadav
    Indian Journal of Physical Medicine and Rehabilitation.2025; 35(2): 128.     CrossRef
  • Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels
    Maryam Hadadi, Mohammad Mojtaba Farazi, Mehrnaz Mehrabani, Mahsa Tashakori-Miyanroudi, Zahra Behroozi
    Scientific Reports.2025;[Epub]     CrossRef
  • Clinical Characteristics of Adults Living with a Spinal Cord Injury Across the Continuum of Care: A Population-Based Cross-Sectional Study
    Matteo Ponzano, Anja Declercq, Melissa Ziraldo, John P. Hirdes
    Journal of Clinical Medicine.2025; 14(9): 3060.     CrossRef
  • Astrocytic Inducible Nitric Oxide Synthase Upregulation Contributes to Chronic Below‐Level Neuropathic Pain Following Spinal Cord Injury in Male Rats
    Youngkyung Kim, Hyunggoo Kang, Young Wook Yoon
    European Journal of Pain.2025;[Epub]     CrossRef
  • Long-term dynamics of the spinal cord injury neuroinflammatory response and sensory dysfunction in female mice
    Neal J. Wrobel, Quan Shen, Dustin H. Kim, Bahar Adavoody, Daniela Garcia Prada, Richard G. Fessler, Brian T. David
    Brain, Behavior, and Immunity.2025; 129: 143.     CrossRef
  • Analysis of electroencephalography oscillation characteristics in spinal cord injury patients with neuropathic pain
    Dezheng Wang, Xinting Zhang, Shouwei Yue, Dongju Guo, Lei Jiang, Chao Feng, Jiancai Leng, Shaolei Huang, Yang Zhang, Fangzhou Xu
    Brain Research Bulletin.2025; 229: 111438.     CrossRef
  • Occurrence of neuropathic pain and its characteristics in patients with traumatic spinal cord injury
    Arun Yadav, Mrinal Joshi
    The Journal of Spinal Cord Medicine.2024; 47(6): 952.     CrossRef
  • Post-discharge follow-up of patients with spine trauma in the National Spinal Cord Injury Registry of Iran during the COVID-19 pandemic: Challenges and lessons learned
    Zahra Azadmanjir, Moein Khormali, Mohsen Sadeghi-Naini, Vali Baigi, Habibollah Pirnejad, Mohammad Dashtkoohi, Zahra Ghodsi, Seyed Behnam Jazayeri, Aidin Shakeri, Mahdi Mohammadzadeh, Laleh Bagheri, Mohammad-Sajjad Lotfi, Salman Daliri, Amir Azarhomayoun,
    Chinese Journal of Traumatology.2024; 27(3): 173.     CrossRef
  • Randomised, double-blind, placebo-controlled, parallel-group, multicentric, phase IIA clinical trial for evaluating the safety, tolerability, and therapeutic efficacy of daily oral administration of NFX88 to treat neuropathic pain in individuals with spin
    Pablo V. Escribá, Ángel M. Gil-Agudo, Joan Vidal Samsó, Judith Sánchez-Raya, Sebastián Salvador-de la Barrera, Vanesa Soto-León, Natacha León-Álvarez, Bosco Méndez Ferrer, Miguel David Membrilla-Mesa, Carolina Redondo Galán, Jesús Benito-Penalva, Antonio
    Spinal Cord.2024; 62(8): 454.     CrossRef
  • Low back pain classifications and their associations with disability, quality-of-life, and sociodemographic factors: a comprehensive examination using the PainDETECT questionnaire
    Zachary Gan, Stone Sima, Samuel Lapkin, Ashish D. Diwan
    Current Medical Research and Opinion.2024; 40(8): 1379.     CrossRef
  • Research progress in neuropathic pain after spinal cord injury: a bibliometric study from 2013 to 2024
    Qin Huiqing, Lin Weishan, Gui Yuchang, Tang Yun, Xu Jianwen
    Frontiers in Neurology.2024;[Epub]     CrossRef
  • Prevalence and Determinants of Pain in Spinal Cord Injury During Initial Inpatient Rehabilitation: Data From the Dutch Spinal Cord Injury Database
    Tim C. Crul, Marcel W.M. Post, Johanna M.A. Visser-Meily, Janneke M. Stolwijk-Swüste
    Archives of Physical Medicine and Rehabilitation.2023; 104(1): 74.     CrossRef
  • Ectopic expression of Nav1.7 in spinal dorsal horn neurons induced by NGF contributes to neuropathic pain in a mouse spinal cord injury model
    Yan Fu, Liting Sun, Fengting Zhu, Wei Xia, Ting Wen, Ruilong Xia, Xin Yu, Dan Xu, Changgeng Peng
    Frontiers in Molecular Neuroscience.2023;[Epub]     CrossRef
  • Precision neuromodulation: Promises and challenges of spinal stimulation for multi-modal rehabilitation
    Maria F. Bandres, Jefferson L. Gomes, Gerson N. Moreno Romero, Avery R. Twyman, Jacob Graves McPherson
    Frontiers in Rehabilitation Sciences.2023;[Epub]     CrossRef
  • A Silver Lining of Neuropathic Pain: Predicting Favorable Functional Outcome in Spinal Cord Injury
    Mu-Lan Xu, Xiang-Bo Wu, Ying Liang, Ning Li, Xu Hu, Xiao-Dong Lin, Miao-Qiao Sun, Chun-Qiu Dai, Dan Niu, Yan-Rong Zhang, Hui Cao, Chen-Guang Zhao, Xiao-Long Sun, Hua Yuan
    Journal of Pain Research.2023; Volume 16: 2619.     CrossRef
  • Feasibility of using remotely delivered Spring Forest Qigong to reduce neuropathic pain in adults with spinal cord injury: a pilot study
    Ann Van de Winckel, Sydney T. Carpentier, Wei Deng, Lin Zhang, Angela Philippus, Ricardo Battaglino, Leslie R. Morse
    Frontiers in Physiology.2023;[Epub]     CrossRef
  • An Exploratory EEG Analysis on the Effects of Virtual Reality in People with Neuropathic Pain Following Spinal Cord Injury
    Yvonne Tran, Philip Austin, Charles Lo, Ashley Craig, James W. Middleton, Paul J. Wrigley, Philip Siddall
    Sensors.2022; 22(7): 2629.     CrossRef
  • Systematic analysis of critical genes and pathways identified a signature of neuropathic pain after spinal cord injury
    Zefu Li, Huiying Bai, Ruoyu Zhang, Bohan Chen, Junmin Wang, Bohan Xue, Xiuhua Ren, Jiarui Wang, Yanjie Jia, Weidong Zang, Jian Wang, Xuemei Chen
    European Journal of Neuroscience.2022; 56(2): 3991.     CrossRef
  • Phenotypes of Motor Deficit and Pain after Experimental Spinal Cord Injury
    Volodymyr Krotov, Volodymyr Medvediev, Ibrahim Abdallah, Arseniy Bozhenko, Mykhailo Tatarchuk, Yevheniia Ishchenko, Leonid Pichkur, Serhii Savosko, Vitaliy Tsymbaliuk, Olga Kopach, Nana Voitenko
    Bioengineering.2022; 9(6): 262.     CrossRef
  • Peripheral Immune Dysfunction: A Problem of Central Importance after Spinal Cord Injury
    Marisa Jeffries, Veronica Tom
    Biology.2021; 10(9): 928.     CrossRef
  • 6,135 View
  • 187 Download
  • 24 Web of Science
  • 23 Crossref
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