Most studies concerning congenital mirror movements (CMMs) have been focused on the motor organization in the distal hand muscles exclusively. To the best of our knowledge, there is no data on motor organization pattern of lower extremities, and a scarcity of data on the significance of forearm and arm muscles in CMMs. Here, we describe the case of a 19-year-old boy presenting mirror movements. In these terms, a 10-year transcranial magnetic stimulation study demonstrated that the motor organization pattern of the arm muscles was different from that of distal hand and forearm muscles even in the same upper extremity, and that the lower extremities showed the same pathways as healthy children. Moreover, in this case, an ipsilateral motor evoked potentials (MEPs) for distal hand muscles increased in amplitude with age, even though the intensity of mirror movements decreased. In the arm muscles, however, it was concluded that the contralateral MEPs increased in amplitude with age.
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Neurophysiology in the mirror: A tri-layer model of mirror movements informed by TMS evidence Luca Sebastianelli, Viviana Versace, Davide Ferrazzoli, Paola Ortelli, Eugen Trinka, Johann Sellner, Raffaele Nardone Clinical Neurophysiology.2026; 184: 2111692. CrossRef
Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines Simone Rossi, Andrea Antal, Sven Bestmann, Marom Bikson, Carmen Brewer, Jürgen Brockmöller, Linda L. Carpenter, Massimo Cincotta, Robert Chen, Jeff D. Daskalakis, Vincenzo Di Lazzaro, Michael D. Fox, Mark S. George, Donald Gilbert, Vasilios K. Kimiskidis, Clinical Neurophysiology.2021; 132(1): 269. CrossRef
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Mirror Movements in Acquired Neurological Disorders: A Mini-Review Ping Liu, Yuan Yuan, Ning Zhang, Xiaoyan Liu, Lihua Yu, Benyan Luo Frontiers in Neurology.2021;[Epub] CrossRef
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