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Ann Rehabil Med 2013 Apr; 37(2): 295-299
Lofgren's Syndrome—Acute Onset Sarcoidosis and Polyarthralgia: A Case Report
Chan Woo Byun, MD, Seung Nam Yang, MD, Joon Shik Yoon, MD, Se Hwa Kim, MD
Department of Physical Medicine and Rehabilitation, Korea University Guro Hospital, Seoul, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Lofgren's syndrome is an acute form of sarcoidosis characterized by erythema nodosum, bilateral hilar lymphadenopathy (BHL), and polyarthralgia or polyarthritis. This syndrome is common among Caucasians but rare in the Korean population. A 44-year-old woman was admitted to our hospital complaining of polyarthralgia. A chest radiograph revealed BHL and nodular shadows. Angiotensin-converting enzyme levels were within the normal range. Tissue biopsy from a mediastinum lymph node showed noncaseating granulomas. We diagnosed her with Lofgren's syndrome, an acute form of sarcoidosis.
Sarcoidosis, Arthritis, Lymph node
Ann Rehabil Med 2013 Apr; 37(2): 295-299

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