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Journal of the Korean Academy of Rehabilitation Medicine 1996;20(4):37.
Quadriplegia Secondary to Organophosphate Intoxication -Case report-
Jun Min Park, M.D., Kwang Su Kim, M.D., Min Ho Chun, M.D. , Sang Bae Ha, M.D.
Department of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine
유기인제재 중독으로 사지마비를 보였던 증례 보고 -증례 보고-
박준민, 김광수, 전민호, 하상배
울산의대 서울중앙병원 재활의학과
Abstract

Organophosphate has three major applications; insecticides, petroleum additives, and modifiers of plastic. According to the latent period, orgaophosphate intoxication is classified by acute syndrome, intermediate syndrome, organophasphate induced delayed polyneuropathy(OPIDP). Acute syndrome, occurring shortly after exposure, due to an excessive acetylcholine effect on muscarinic receptors, is characterized by gastrointestinal distress, miosis, lacrimation, and no weakness. As a treatment, atropinization is effective. Intermediate syndrome, occurring 12 to 96 hours after exposure, due to an acetylcholine effect on nicotinic receptors, results in limb and respiratory muscle weakness. There is no effective treatment. OPIDP is less common than the cholinergic reaction and occurs after a latent period of 7 to 21 days. The initial neurological symptom of OPIDP include cramping calf pain, tingling, burning sensations in the feet and occasionally in the hands. Weakness is an early and invariable finding. Spasticity and ataxia can be seen in the case of involving the central nervous system. There is also no specific treatment. The prognosis, in mild affected individuals, presumably with less exposure, has been good. They generally make a nearly complete recovery. Others with more severe initial deficit are left with varing degrees of morbidity, which include sequalae of both peripheral, central nervous system damage, and recovery is slow and usually incomplete.

We experienced a case of organophosphate intoxication which included acute syndrome, intermediate syndrome, and OPIDP. At the time of transfer to rehabilitation department, he was a quadriplegia, who had the delayed symptome of organophosphate intoxication.

We report an example of the quadriplegia which results from organophosphate intoxication.

Key Words: OPIDP, Organophosphate, Intoxication, OPIDP, Quadriplegia


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